Thats interesting and as it goes biofilms came up yesterday with kinesiologist.

Got to see the head practitioner and henow has me at the point where we can chuck more at my gut problems after months of calming the nervous system - very important process!!

Detectedone more parasite - this time worms ( yuck) has me on Tri Plex for this.Also has me on N-Acetyl Cysteine to break down biofilms in mouth - next will be the gut Im told and he assures me that in six weeks time my gut will finally feel the best its been in years - thats a big guarantee that you dont ordinarily get from a practitioner

Also put meon BaikalSkullcap, Ill have to check again exactly why he has me on this as it has many uses - everything from sleep to liver to OCD issues.

Lower back is playing up but he said thats expected as liver is clearing and it interacts with muscles in back, gave me these little wedges to put in between toes to trigger a point that holds the neck in place more strongly.

Anyway, these were the things found, right or wrong and I dont suspect hes just making shit up so Im trusting in the process. Ive certainly never had any comprehensive findings seeing a regular GP other than the odd blood test.

Just saying if you have the time and money you could do worse than working with a good kinesiologist imo

5 hours ago, User2 said:

Good catch - it wascreatinine. My mistake.

Thanks for clarifying. Tends to rise on Tane so wondering if things go haywire after treatment.

17 hours ago, Francisco..Blanquez said:

As much b12 you have...more acne you have.

Cafeine decrease the amout of b12 our body absorv.....

You're saying b12 causes acne? There are some studies to support this. Could be one reason that accutane works so well.

15 hours ago, guitarman01 said:

Speaking of tests, I tested positive for all candida antibodies. This was a pretty cheap test from walkinlabs where you can get your own blood tests. Something this simple could be a start. A Type of dysbiosis that never corrects itself. Youd maybe be talking about something that becomes a part of you, that forms highly resistant biofilms that can only be eradicated and replaced with beneficial biofilms, from beneficial microbes.

If this were true, I, along with current research doesn't quite know how to correct this if possible. Whats right, whats wrong.

I am heavily focused on the bifido species, being that this is dominant from birth, and happens to metabolise retinoic acid. In some this could almost be considered a type of birth defect if lacking. Again if true, what happens if you were only to figure this out 20 years later? or Since birth?

 

may

15 hours ago, guitarman01 said:

Speaking of tests, I tested positive for all candida antibodies. This was a pretty cheap test from walkinlabs where you can get your own blood tests. Something this simple could be a start. A Type of dysbiosis that never corrects itself. Youd maybe be talking about something that becomes a part of you, that forms highly resistant biofilms that can only be eradicated and replaced with beneficial biofilms, from beneficial microbes.

If this were true, I, along with current research doesn't quite know how to correct this if possible. Whats right, whats wrong.

I am heavily focused on the bifido species, being that this is dominant from birth, and happens to metabolise retinoic acid. In some this could almost be considered a type of birth defect if lacking. Again if true, what happens if you were only to figure this out 20 years later? or Since birth?

ma±±±±±±±±±±maybe that is why why we feel better on a free gluten and SUGAR diet. ca±nduida eat sugar...

±There is another ting, I experienced myself that when eating fermented red cabbage... my cra±ving for sugar ±decreased . It contains good bacteria ±, maybe they kill candida

8 minutes ago, gutskinaxis said:

You're saying b12 causes acne? There are some studies to support this. Could be one reason that accutane works so well.

of course, that is the why acutane Works.

@StopAccutane

I think intestinal permeability can play a role. I've possibly noticed this coincide with symptoms, along with gut dysmotility. HPA axis dysfunction, the eccentric nervous system regulating blood flow and gastric emptying.

people talk about not getting sick anymore, (same in CFS) immune regulation, meaning what the body decides to go after, what it leaves alone or tolerates.

Good bacteria vs bad bacteria, they are looking at this with parkinson's and other neurodegenerative diseases. Bad bacteria that outnumber the good and take hold.

How are they looking at modulating all of this?

Well it seems like just about everything you ingest from food to drugs can cause shifts, its when these shifts become more negative then positive and more permanent than temporary,this could become the bigger problem.

Also this probably plays a role in the aging process in general.

How are they looking at modulating this outside of diet alone?

Probiotics, prebiotics, antibiotics, antifungals.

On probiotics, they all say species and strains matter, the ability to form biofilms might matter.

duration, dosage, frequency all matter.

There is some newer research that some probiotics could permanently recolonize.

Stable Engraftment of Bifidobacterium longum AH1206 in the Human Gut Depends on Individualized Features of the Resident Microbiome.

https://www.ncbi.nlm.nih.gov/pubmed/27693307/

Live bacteria (such as probiotics) have long been used to modulate gut microbiota and human physiology, but their colonization is mostly transient. Conceptual understanding of the ecological principles as they apply to exogenously introduced microbes in gut ecosystems is lacking. We find that, when orally administered to humans, Bifidobacterium longum AH1206 stably persists in the gut of 30% of individuals for at least 6months without causing gastrointestinal symptoms or impacting the composition of the resident gut microbiota. AH1206 engraftment was associated with low abundance of resident B.longum and underrepresentation of specific carbohydrate utilization genes in the pre-treatment microbiome. Thus, phylogenetic limiting and resource availability are two factors that control the niche opportunity for AH1206 colonization. These findings suggest that bacterial species and functional genes absent in the gut microbiome of individual humans can be reestablished, providing opportunities for precise and personalized microbiome reconstitution.

These results demonstrate that a set of genes unique to AH1206 remained detectable in persisters for around 200days after consumption of the strain, confirming long-term persistence.

This is just one example of one strain of one species.

Good news. I can control my inflamatory levels. I just got the blood test result. ESR (VSG in Spanish) = 11. Very good level of colesterol and triglicerides. 197 and 71. That has been after avoiding any kind of sugar and gluten. I have give advise in others messages before.

Do not thust in any kind of proceded food or suplement... . I do not eat gluten, sugar and procesed food. I eat rice, potato, beens..... all natural foods

On 2/6/2019 at 3:34 AM, gutskinaxis said:

You're saying b12 causes acne? There are some studies to support this. Could be one reason that accutane works so well.

Just updating, although my hair is softer on B12 it may be making my folliculitis worse, maybe increased oil production not sure.

Took a while to happen but now I'm not too sure about b12.

Maybe only good in moderation.

here's more 

Probiotic, Prebiotic, and Brain Development

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707719/

Recently, a number of studies have demonstrated the existence of a link between the emotional and cognitive centres of the brain and peripheral functions through the bi-directional interaction between the central nervous system and the enteric nervous system.

The micro-organisms that inhabit the human gastrointestinal tract (GI) have been implicated in the development and functioning of a number of basic physiological processes, such as digestion, immunity, and the maintenance of homeostasis. The GI microbiota may also play a role in multiple diseases, ranging from inflammation to obesity [1,2]. Recently, many studies have shown that gut microbiota play a very important role in the development and function of the central nervous system (CNS) through specific channels, such as metabolic, neuroendocrine, and immune pathways [3]. In particular, these researchers have found bi-directional communication between the brain and the gut microbiota, denominated the microbiota“gut“brain axis [4,5,6].

On 2/8/2019 at 7:21 AM, guitarman01 said:

here's more 

Probiotic, Prebiotic, and Brain Development

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707719/

Recently, a number of studies have demonstrated the existence of a link between the emotional and cognitive centres of the brain and peripheral functions through the bi-directional interaction between the central nervous system and the enteric nervous system.

The micro-organisms that inhabit the human gastrointestinal tract (GI) have been implicated in the development and functioning of a number of basic physiological processes, such as digestion, immunity, and the maintenance of homeostasis. The GI microbiota may also play a role in multiple diseases, ranging from inflammation to obesity [1,2]. Recently, many studies have shown that gut microbiota play a very important role in the development and function of the central nervous system (CNS) through specific channels, such as metabolic, neuroendocrine, and immune pathways [3]. In particular, these researchers have found bi-directional communication between the brain and the gut microbiota, denominated the microbiota“gut“brain axis [4,5,6].

Hey guitarman, 

You might be interested listening to this podcast about the gut microbiome. [removed]

It™s from 2015 but still relevant to your thoughts above.

yea looks like a lot of good info @StopAccutane

Ill take a listen when I have the chance.

how many people here follow a strict gluten free diet?

Regarding dysbiosis/candida overgrowth/pseudo-celiac disease (potentially caused by the suppression of TLR-2 by Isotretinoin),

I've just finished taking a combination of VSL#3 and Bifidobacterium infantis 35624, but so far I haven't noticed any significant improvement.

And since I don't know any better probiotics, I will most likely have tofind a good gastroenterologist and ask him for antifungals or some anti-sibo drugs (small intestinal bacterial overgrowth is the first thing that comes to my mind when I think about my post-accutane symptoms).

Has anyone thought about the NAD+ anti aging pathway? And supplementing with nicotinamide riboside?

https://www.fightagainstacne.com/blog/anti-aging-compound-fights-acne

2 hours ago, VanceAstro said:

Regarding dysbiosis/candida overgrowth/pseudo-celiac disease (potentially caused by the suppression of TLR-2 by Isotretinoin),

I've just finished taking a combination of VSL#3 and Bifidobacterium infantis 35624, but so far I haven't noticed any significant improvement.

And since I don't know any better probiotics, I will most likely have tofind a good gastroenterologist and ask him for antifungals or some anti-sibo drugs (small intestinal bacterial overgrowth is the first thing that comes to my mind when I think about my post-accutane symptoms).

Hi VanceAstro,

Thanks for your comment! How many active cultures are you taking? 100billion? 400 billion? More?

Do you have a diet that allows these probiotics to flourish? How long have you been taking them?

I also read that you must first solve adrenal and thyroid issues for your gut to be repaired. Have you addressed these issues as well?

Thanks for your time

1 hour ago, gutskinaxis said:

Has anyone thought about the NAD+ anti aging pathway? And supplementing with nicotinamide riboside?

https://www.fightagainstacne.com/blog/anti-aging-compound-fights-acne

I just did a test on my Cholsterol and triglycerides. I found that my LDL is at 128 (normal range should be less than 100). Im thinking this is because of B12 not being able to be methylized through my MTRR polymorphism and increasing homocysteine levels -> causing fatty adipose tissue. I will try NAD to try to combat that LDL cholesterol levels. Ive read that typically LDL is not too dangerous UNLESS paired with a poor autoimmune system and poor gut. Endotoxins will bindto LDL and store in adipose tissue mainly liver.

26 minutes ago, StopAccutane said:

Hi VanceAstro,

Thanks for your comment! How many active cultures are you taking? 100billion? 400 billion? More?

Do you have a diet that allows these probiotics to flourish? How long have you been taking them?

I also read that you must first solve adrenal and thyroid issues for your gut to be repaired. Have you addressed these issues as well?

Thanks for your time

I took 224 billion of VSL#3 and2 billion ofBifidobacterium infantis 35624 daily for around one month.

Today I decided to give another chance toBifidobacterium infantis 35624 and I've ordered another 90 caps (1 billion each).

ButI'm really eager to try some antifungals.

2 hours ago, StopAccutane said:

Hi VanceAstro,

Thanks for your comment! How many active cultures are you taking? 100billion? 400 billion? More?

Do you have a diet that allows these probiotics to flourish? How long have you been taking them?

I also read that you must first solve adrenal and thyroid issues for your gut to be repaired. Have you addressed these issues as well?

 

Thanks for your time

I just did a test on my Cholsterol and triglycerides. I found that my LDL is at 128 (normal range should be less than 100). Im thinking this is because of B12 not being able to be methylized through my MTRR polymorphism and increasing homocysteine levels -> causing fatty adipose tissue. I will try NAD to try to combat that LDL cholesterol levels. Ive read that typically LDL is not too dangerous UNLESS paired with a poor autoimmune system and poor gut. Endotoxins will bindto LDL and store in adipose tissue mainly liver.

I think NAD+, or specifically nicotinamide riboside, is helpful for everyone.

I was curious if anyone here tried a prolonged water fast and had any results.

thx

4 hours ago, VanceAstro said:

Today I decided to give another chance toBifidobacterium infantis 35624 and I've ordered another 90 caps (1 billion each).

ButI'm really eager to try some antifungals.

Im not sure where you are, but here in the states a higher dosage of bifido 35624, which has actually been reclassified as longum not infantis became available at 5 billion cfu per pill.

Im taking 10 billion daily, this is still rather expensive at 60 dollars a month, but this dosage until now was not feasible with the 1 billion capsules.

This 10 billion per day was the same dosage they used in the CFS study that lowered inflammatory markers.

Ive also looked at this strain specifically because you can find wordage in recent studies that metabolizing retinoic acid was a key regulatory feature of this bacterium.

"Citing evidence that the microbes in the gut actually regulate the immune system outside of the gut, people with chronic fatigue syndrome were given sachets containing eitherBifidobacterium infantis 35264(110¹⁰CFU viable)or maltodextrin (5 grams) for eight weeks. At the end of eight weeks the three cytokine levels were measured to see if inflammation was indeed reduced."

https://www.healthrising.org/blog/2013/07/15/probioti-therapy-knocks-down-inflammation-in-chronic-fatigue-syndrome/

WithB. infantissignificantly reducing the levels of all three pro-inflammatory markers, it appeared that eight weeks ofB. infantissupplementation did reduce the inflammation present in this disorder.

as far as having other things going on simultaneously, I tested positive for all the Candida antibodies Mayo used to test.

Discontinued: Candida albicans Serology and Antigen Tests

http://lab.spectrumhealth.org/2018/07/30/discontinued-candida-albicans-serology-and-antigen-tests/

Candidaantibodies are detected in 20-30% of healthy individuals

you can also look at the flip side of this, 70 to 80 percent might have something going on.

Any positive results from this yet?

38 minutes ago, guitarman01 said:

Im not sure where you are, but here in the states a higher dosage of bifido 35624, which has actually been reclassified as longum not infantis became available at 5 billion cfu per pill.

Im taking 10 billion daily, this is still rather expensive at 60 dollars a month, but this dosage until now was not feasible with the 1 billion capsules.

This 10 billion per day was the same dosage they used in the CFS study that lowered inflammatory markers.

Ive also looked at this strain specifically because you can find wordage in recent studies that metabolizing retinoic acid was a key regulatory feature of this bacterium.

"Citing evidence that the microbes in the gut actually regulate the immune system outside of the gut, people with chronic fatigue syndrome were given sachets containing eitherBifidobacterium infantis 35264 (110¹⁰CFU viable) or maltodextrin (5 grams) for eight weeks. At the end of eight weeks the three cytokine levels were measured to see if inflammation was indeed reduced."

https://www.healthrising.org/blog/2013/07/15/probioti-therapy-knocks-down-inflammation-in-chronic-fatigue-syndrome/

WithB. infantis significantly reducing the levels of all three pro-inflammatory markers, it appeared that eight weeks ofB. infantis supplementation did reduce the inflammation present in this disorder.

 

as far as having other things going on simultaneously, I tested positive for all the Candida antibodies Mayo used to test.

Discontinued: Candida albicans Serology and Antigen Tests

http://lab.spectrumhealth.org/2018/07/30/discontinued-candida-albicans-serology-and-antigen-tests/

Candidaantibodies are detected in 20-30% of healthy individuals

you can also look at the flip side of this, 70 to 80 percent might have something going on.

 

Any positive results seen from this yet?

4 hours ago, guitarman01 said:

Im not sure where you are, but here in the states a higher dosage of bifido 35624, which has actually been reclassified as longum not infantis became available at 5 billion cfu per pill.

Im taking 10 billion daily, this is still rather expensive at 60 dollars a month, but this dosage until now was not feasible with the 1 billion capsules.

This 10 billion per day was the same dosage they used in the CFS study that lowered inflammatory markers.

Ive also looked at this strain specifically because you can find wordage in recent studies that metabolizing retinoic acid was a key regulatory feature of this bacterium.

"Citing evidence that the microbes in the gut actually regulate the immune system outside of the gut, people with chronic fatigue syndrome were given sachets containing eitherBifidobacterium infantis 35264 (110¹⁰CFU viable) or maltodextrin (5 grams) for eight weeks. At the end of eight weeks the three cytokine levels were measured to see if inflammation was indeed reduced."

https://www.healthrising.org/blog/2013/07/15/probioti-therapy-knocks-down-inflammation-in-chronic-fatigue-syndrome/

WithB. infantis significantly reducing the levels of all three pro-inflammatory markers, it appeared that eight weeks ofB. infantis supplementation did reduce the inflammation present in this disorder.

 

as far as having other things going on simultaneously, I tested positive for all the Candida antibodies Mayo used to test.

Discontinued: Candida albicans Serology and Antigen Tests

http://lab.spectrumhealth.org/2018/07/30/discontinued-candida-albicans-serology-and-antigen-tests/

Candidaantibodies are detected in 20-30% of healthy individuals

you can also look at the flip side of this, 70 to 80 percent might have something going on.

 

Actually,Bifidobacterium Longumexists in VSL#3.

As you work on gut, is it important to calm nervous system and also work on breaking downbiofilms in both mouth and gut? ( N Acetyl Cysteine )

And at the same time Ive beentold its advisable to take something like Baikal Skullcap - thishelps the body rid this bad bacteria once its broken down - or so Im told....

Anyone know anything about these processes and their importance before hitting asupplement or probiotic that may not be timed right in terms ofrebuilding the gut?

14 hours ago, GeRalt said:

I was curious if anyone here tried a prolonged water fast and had any results.

thx

I have done 3, 7, 14, and 20 day water fasts, they definitely help deplete stored vitamin A from tissues, following a low vitamin A diet post fast and refeed is important to continue the depletion.

1 hour ago, under_tow said:

 

I have done 3, 7, 14, and 20 day water fasts, they definitely help deplete stored vitamin A from tissues, following a low vitamin A diet post fast and refeed is important to continue the depletion.

 

have you experienced any improvements with dry skin and dry eyes after your water fasts. and if yes would you say that the improvements were permanent?

43 minutes ago, Roland1968 said:

 

have you experienced any improvements with dry skin and dry eyes after your water fasts. and if yes would you say that the improvements were permanent?

 

Just doing 16 hour fasts has helped me with dry eyes, general eye discomfort