Well if yall wanna trial Finasteride by all means go for it! The only way Id get near it is if it truly works for everyone who has tried.

2 hours ago, tanedout said:

So you think that people may have been able to avoid getting stuck with side effects if they tapered the dosage when stopping, to let the receptors re-adjust? Like going from 20mg, then 10mg then 5mg etc?

I believe so.
it is easier for the body to adjust the receptors with less 10 to 5 mg at a time than to stop taking 80 or 40 mg of accutane from scratch, the receptors lose sensitivity to something with high dose much faster than that when you take little to increase, especially if it is something that your body did not depend on before

A simple example is caffeine, in 5 to 7 days your receptors are already weak, but to regain sensitivity you need practically double or triple the time without taking caffeine, as it is something that your body did not need before and you just started to ingest

But I may be wrong if this would work with accutane, it's just a way I thought

35 minutes ago, Colinboko said:

Well if yall wanna trial Finasteride by all means go for it! The only way Id get near it is if it truly works for everyone who has tried.

Yes, I was very scared to start this, but I decided to try after seeing some recoveries
it is complicated to use something that causes practically the same effects that accutane caused to me with several cases scattered around the world

1 hour ago, namelk said:

I believe so.
it is easier for the body to adjust the receptors with less 10 to 5 mg at a time than to stop taking 80 or 40 mg of accutane from scratch, the receptors lose sensitivity to something with high dose much faster than that when you take little to increase, especially if it is something that your body did not depend on before

A simple example is caffeine, in 5 to 7 days your receptors are already weak, but to regain sensitivity you need practically double or triple the time without taking caffeine, as it is something that your body did not need before and you just started to ingest

But I may be wrong if this would work with accutane, it's just a way I thought
Yes, I was very scared to start this, but I decided to try after seeing some recoveries
it is complicated to use something that causes practically the same effects that accutane caused to me with several cases scattered around the world

Well keep us updated on how it goes!!!

Had a CRP test and neoplastic-somethin done on Thursday!

Will keep yall updated.

Hoping I have some low grade inflammation going on. Would make a lot of sense for me. Hence never getting sick

Low t > more estrogen > more inflammation

Also have you guys seen the page of the guy who had gyno from Accutane amongst other symptoms (depression, fatigue, aching muscles) ? He repaired his sex hormones with estrogen blockers I believe. Just curious if anyone had seen it. Heres the link

https://www.heart-health-guide.com/causes-of-hormonal-imbalance.html

1 hour ago, Colinboko said:

Had a CRP test and neoplastic-somethin done on Thursday!

Will keep yall updated.

Hoping I have some low grade inflammation going on. Would make a lot of sense for me. Hence never getting sick

Low t > more estrogen > more inflammation

Also have you guys seen the page of the guy who had gyno from Accutane amongst other symptoms (depression, fatigue, aching muscles) ? He repaired his sex hormones with estrogen blockers I believe. Just curious if anyone had seen it. Heres the link

https://www.heart-health-guide.com/causes-of-hormonal-imbalance.html

Good find - I think Id entertain the idea of going on an Estrogen Blocker over say Finasteride.

What I would ask though, how do you get a prescription from a doctor when your blood levels are within range?? ( I think most of us are always within range albeit sometimes low but not necessarily out of range )

This guy got lucky in a sense, his blood work actually showed something which he was able to leverage!!!

Edit

3 hours ago, Colinboko said:

Had a CRP test and neoplastic-somethin done on Thursday!

"neoplastic" what kind of test was this? Thats not a good word. what ever happened with that other test result and then finding protein in your urine? was it a high number? Did they just chalk this up to dehydration? If you havent, id sign up to look at all your test results online. Sometimes they leave out information.

Heres something odd. Ive made notes over the past few months of having a pressure behind my left eye. Over the last few weeks this pressure has shifted to behind my right eye. Today it isnt as bad as it has been over the last week.

however, last night I was laying in bed, I realised my right eye is very noticeably lesserperforming as my left eye is in low light conditions. The room was significantly darker if I held my left eye closed. How bizarre. Wtf is this. How did this pressure that has shifted places cause limited vision?

Side note: I am a week through my allochol 2 week detox attempting a bile dump. Nothing drastic to report as of yet. I dont believe there is a correlation between the allochol and the pressure I am experiencing.

3 hours ago, guitarman01 said:

6 hours ago, Colinboko said:

Had a CRP test and neoplastic-somethin done on Thursday!

"neoplastic" what kind of test was this? Thats not a good word. what ever happened with that other test result and then finding protein in your urine? was it a high number? Did they just chalk this up to dehydration? If you havent, id sign up to look at all your test results online. Sometimes they leave out information.

I believe the neoplasm one was when they found an abnormal protein on my electrophoresis and wanted to test for myeloma. I didnt have a ridiculously high amount of protein in my urine but because I did have some they wanted to test my CRP levels and see if it could be inflammation related. And when I went to get my CRP checked the nurse told me I had another request that my doc wanted which was the neoplasm one. So to be honest, not really sure..

On 15.12.2017 at 3:44 AM, pimple pimp said:

jesus christ youre 42!? wtf was ur dose and how long were u on??

have you tried increasing sodium and carb intake ?

im talking in the range of 30+ grams of salt a day

I am 49 
 

1 hour ago, Roland1968 said:

I am 49 
 

What year were you poisoned??

Of course there were computers around when I took in late 90™s but I didn™t have one, stuff like the Internet was in its infancy......regardless you trust that doctors know what they™re doing right!!

They™ve got our best interests at heart, they™d never harm us.....

5 hours ago, TrueJustice said:

What year were you poisoned??

Of course there were computers around when I took in late 90s but I didnt have one, stuff like the Internet was in its infancy......regardless you trust that doctors know what theyre doing right!!

Theyve got our best interests at heart, theyd never harm us.....

It was in 2001. There was actually a forum, where accutane was discussed. Unfortunately reviews were mostly positive.

12 hours ago, Iamme. said:

Heres something odd. Ive made notes over the past few months of having a pressure behind my left eye. Over the last few weeks this pressure has shifted to behind my right eye. Today it isnt as bad as it has been over the last week.

however, last night I was laying in bed, I realised my right eye is very noticeably lesserperforming as my left eye is in low light conditions. The room was significantly darker if I held my left eye closed. How bizarre. Wtf is this. How did this pressure that has shifted places cause limited vision?

I posted something a while back that could be related to this.Tiny muscle like tissues behind the eye that expand and contract and regulate blood flow and hence oxygen. If there is a some muscle weakness here, maybe it stays in a contracted state and this is where you feel a little bit of pressure.

Contractile proteins in pericytes at the blood-brain and blood-retinal barriers.

https://www.ncbi.nlm.nih.gov/pubmed/11577244
There are tissues that have muscle like property that are capable of contracting that can regulate the tiniest of blood flow.

Evidence from a variety of sources suggests that pericytes have contractile properties and may therefore function in the regulation of capillary blood flow.
results add support for a contractile role in pericytes of the CNS microvasculature, similar to that of vascular smooth muscle cells.

Looking at if this applies to the brain. Which could include Vascular constriction, reduced cerebral blood flow.
One of the tests to look into this if anyone ever gets to that point.
arterial spin labeling MRI
http://fmri.research.umich.edu/research/main_topics/asl.php

Now looking what I have been looking at,

Vitamin K - Page 195 - Google Books Result

Gas6 and protein S. Vitamin K-dependent ligands for the Axl receptor ...

Gas6-Axl system to regulate cell survival, proliferation, migration, adhesion and phagocytosis. Consequently, altered activity/expression of its components has been detected in a variety of pathologies such as cancer and vascular, autoimmune and kidney disorders

4 hours ago, Roland1968 said:

It was in 2001. There was actually a forum, where accutane was discussed. Unfortunately reviews were mostly positive.

The problem is naturally people will look for the positives, and try and avoid the negatives. I remember looking at side effects (2010) and essentially coming to the conclusion that the main issue was it potentially causing depression, but only in those who were prone to it.

What's crazy though is propecia has pretty much all the sides on the packet, including ED etc but people still take it. There are guys on propeciahelp who've been on that forum, reading all the stories, then risking it anyway - and then getting hit with the sides.

I also read something recently with SSRI's, and it reckoned as many as 10% of users get stuck with sides (PSSD), but with these often being sexual sides these go under-reported due to the stigma. Think how many people go on SSRI's - hugely more than on accutane. There's also a whole host of other drugs causing the same sides as we get from accutane/propecia/ssri's too.

And that's before you even get started on opioids - tens of thousands of deaths per year, yet they're still being prescribed all the time?? Many people don't even know they've been given opioids, then end up addicted and ultimately end up dead.

WTF is going on?!

Big pharmaceutical companies have absolutely got the global healthcare industry by the balls, and it's all about profits.

Anyone had an amino acid panel done??

@tanedout what's an Amino acid panel?

Hey,

i havent visited this forum in a while because I found it extremely unhelpful, but I thought Id give my advice to those suffering from my symptoms.

After Accutane, I was diagnosed with:

Fibromyalgia
Sebhorric Dermatitis
Chronic Migraines
IBS
Major Depressive Disorder

if you have any of the above symptoms, this is what has helped the most:

Fibro: Cymbalta (SNRI), Accupuncture, CBD extract applied to sore muscles

Sebhorric Sernatitis: Ketoconazole Shampoo and Tea Tree oil, olive oil on the scalp too.

IBS: Peppermint Oil capsules

Depression: Therapy, Pain management therapy, meditation

Above everything else, healthy diet and excercise. Seriously, everything else just controls the symptoms but healthy eating and excercise is the only thing that can reverse its effects.

Lots of root vegetables, fruits, water, etc.

the only thing I will potentially try is Lyrica and LDN in the future, but so far my symptoms are manageable now with what I am doing.

Oh, and cannabis is truly a wonder drug that helps with a lot of symptoms.

20 minutes ago, Jorcruz24 said:

Hey,

i havent visited this forum in a while because I found it extremely unhelpful, but I thought Id give my advice to those suffering from my symptoms.

After Accutane, I was diagnosed with:

Fibromyalgia
Sebhorric Dermatitis
Chronic Migraines
IBS
Major Depressive Disorder

if you have any of the above symptoms, this is what has helped the most:

Fibro: Cymbalta (SNRI), Accupuncture, CBD extract applied to sore muscles

Sebhorric Sernatitis: Ketoconazole Shampoo and Tea Tree oil, olive oil on the scalp too.

IBS: Peppermint Oil capsules

Depression: Therapy, Pain management therapy, meditation

Above everything else, healthy diet and excercise. Seriously, everything else just controls the symptoms but healthy eating and excercise is the only thing that can reverse its effects.

Lots of root vegetables, fruits, water, etc.

the only thing I will potentially try is Lyrica and LDN in the future, but so far my symptoms are manageable now with what I am doing.

Oh, and cannabis is truly a wonder drug that helps with a lot of symptoms.

Thx for info.

can you please elaborate on the therapy for depression- what does that involve?
hopefully more than just talking to someone?

Also what brand of CBD oil? Something easily obtainable or the backyard stuff??

That™s what I use. It™s sold at most dispensaries in Oregon. I apply it to a sore muscle and within 5 min the pain is gone. I™m sure any other CBD oil will do the trick. 

I  did a ton of therapy. I have a pain management therapist and mental therapist. 

The two big concepts of therapy that helped the most were Radical Acceptance and Mindfulness. Radical acceptance is accepting your current situation for what it is. This was the hardest one for me. I had so much anger so much frustration so much regret but once you radically accept your situation for what it is you finally begin to heal and move forward. The other one was mindfulness. My flare ups come and go throughout the day, but now my reaction to the pain is much more different than it was before. before, when I would feel the pain I would tense up and completely shut down. Now, I™m mindful of the pain but I don™t let it consume me. I just go about my day normally. 

Its really the difference between  night  and day. 

But not sure, I™m only trying to help those with my side effects, not sure how to help those with depression still after 10 years or ED. I™m sure if you™re still depressed after this long it™s because you haven™t radically accepted your situation for what it is and your still in the denial- bargaining phase 

Thx Jorcruz

I dont know if Im depressed or just jaded beyond belief after 20 years.

Im very tired and that could in itself lead to depression. I mean I agree with the acceptance approach but I dont accept being this way forever, are you saying youve accepted youll never be the same again?

I work and function and do all thats in my power, I feel optimistic enough to think theres still time to change this condition.

18 hours ago, tanedout said:

Anyone had an amino acid panel done??

Yes I have. It was normal. I can show you the results if you like.
Also that heartbeat you say you feel in your head. That isn't normal. That literally sounds like some kind of blood vessel inflammation. Thats why its throbbing. Funny I was just watching ELF the other day and it reminded me of this. He had his finger pricked at the doctor's office and he was like " I can feel my heartbeat in my finger"
I think alot of people can attest to having some type of vascular effect going on at times. Some might not even be aware some of their symptoms could be vascular in nature. Some experts presume this can be hormone driven as well.

52 minutes ago, guitarman01 said:

Yes I have. It was normal. I can show you the results if you like.
Also that heartbeat you say you feel in your head. That isn't normal. That literally sounds like some kind of blood vessel inflammation. Thats why its throbbing. Funny I was just watching ELF the other day and it reminded me of this. He had his finger pricked at the doctor's office and he was like " I can feel my heartbeat in my finger"
I think alot of people can attest to having some type of vascular effect going on at times. Some might not even be aware some of their symptoms could be vascular in nature. Some experts presume this can be hormone driven as well.

homocysteine not elevated? Histidine and cysteine also normal?

2 hours ago, guitarman01 said:

Yes I have. It was normal. I can show you the results if you like.
Also that heartbeat you say you feel in your head. That isn't normal. That literally sounds like some kind of blood vessel inflammation. Thats why its throbbing. Funny I was just watching ELF the other day and it reminded me of this. He had his finger pricked at the doctor's office and he was like " I can feel my heartbeat in my finger"
I think alot of people can attest to having some type of vascular effect going on at times. Some might not even be aware some of their symptoms could be vascular in nature. Some experts presume this can be hormone driven as well.

I read low testosterone and even other hormones can cause circulation problems! When I do yoga and I have to put my feet up in the air, they lose blood flow so quickly and start throbbing I have to bring them back down. My yoga instructor was like wtf? Lol

For those of you with long term joint issues, did you take supplements like fish oil, glucosamine, chondroitin, calcium WHILE on Accutane or only after? Sorry if this is redundant as I havent read farther back than 10 pages

2 hours ago, 808toms said:

For those of you with long term joint issues, did you take supplements like fish oil, glucosamine, chondroitin, calcium WHILE on Accutane or only after? Sorry if this is redundant as I havent read farther back than 10 pages

Im going to say dont bother wasting money on any of those supplements, you are going to have to try something much stronger like CBD oil - everyone has only positive things to say about it!!

Getting into Yoga is also highly advisable regardless of your ability- you will get results over time