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Repairing the long-term damage from Accutane

 
MemberMember
9
(@washer)

Posted : 02/18/2017 9:32 pm

3 hours ago, Nemesisbrady said:

Also quick question what about vitamin a now?

i juice veggies a lot
i don't eat eggs or dairy
but my protein organine drink has vitamin a palimate in it

do we avoid tbis? Or do we need more?
my levels were Normal

only iodine urine was low and zinc was low

Yes, you should avoid all synthetic vitamin A. It's very important, remember that. Start avoiding everything with synthetic vitamin A in it today!

You mention your thyroid a couple of times. Have you tried supplementing Lugols Iodine?

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MemberMember
15
(@nemesisbrady)

Posted : 02/18/2017 10:00 pm

No I haven't they gave me kelp supplement
no relief
and wait so I avoid fruits and veggies ???
alao need the weight gain and those drinks are best ones to do it
it has 25% a in it

thhis sucks feel so hopeless
my skin is so dry and rashy and eyes stuck together
nasal passages dry
scalp

No I haven't they gave me kelp supplement
no relief
and wait so I avoid fruits and veggies ???
alao need the weight gain and those drinks are best ones to do it
it has 25% a in it

thhis sucks feel so hopeless
my skin is so dry and rashy and eyes stuck together
nasal passages dry
scalp

alao does anyone have insomnia and waking up every hour-3 hours

its really ruining me the stress and not knowing
i have all sjorgens symptoms but told I don't have it

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MemberMember
148
(@oli-girl)

Posted : 02/18/2017 10:22 pm

19 minutes ago, Nemesisbrady said:

No I haven't they gave me kelp supplement
no relief
and wait so I avoid fruits and veggies ???
alao need the weight gain and those drinks are best ones to do it
it has 25% a in it

thhis sucks feel so hopeless
my skin is so dry and rashy and eyes stuck together
nasal passages dry
scalp

No I haven't they gave me kelp supplement
no relief
and wait so I avoid fruits and veggies ???
alao need the weight gain and those drinks are best ones to do it
it has 25% a in it

thhis sucks feel so hopeless
my skin is so dry and rashy and eyes stuck together
nasal passages dry
scalp

alao does anyone have insomnia and waking up every hour-3 hours

its really ruining me the stress and not knowing
i have all sjorgens symptoms but told I don't have it

did they do lab work and biopsy to confirm you don't have sjorgrens. though Accutane is known to cause sjrogrens like issues. possibly blepharitis? what labs have you had done, testing etc.

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MemberMember
1803
(@guitarman01)

Posted : 02/19/2017 12:42 am

Some info on retinoid induced hair loss. Not sure if this has been posted yet. Someone mentioned on a forum this is reversible.

Towards dissecting the pathogenesis of retinoid-induced hair loss: all-trans retinoic acid induces premature hair follicle regression (catagen) by upregulation of transforming growth factor-beta2 in the dermal papilla.

Abstract

Diffuse hair loss ranks among the most frequent and psychologically most distressing adverse effects of systemic therapy with retinoids, which severely limits their therapeutic use even where clinically desired. Since the underlying mechanisms of retinoid-induced effluvium are as yet unknown, we have investigated the influence of the prototypic retinoid all-trans retinoic acid (ATRA, tretinoin) on the growth of human scalp hair follicles (HF) in culture. HF in the anagen VI stage of the hair cycle were cultured in the presence of 10(-8) or 10(-10) M ATRA. Compared with controls, hair shaft elongation declined significantly already after 2 d in the ATRA-treated group, and approximately 80% of the ATRA-treated HF had prematurely entered catagen-like stage at day 6, compared with 30% in the control group. This corresponded to an upregulation of apoptotic and a downregulation of Ki67-positive cells in ATRA-treated HF. Since transforming growth factor (TGF)-beta has been implicated as a key inducer of catagen, we next studied whether ATRA treatment had any effect on follicular expression. TGF-beta2 immunoreactivity was detected in the outer root sheath of anagen VI scalp HF. In catagen follicles, TGF-beta2 was also expressed in the regressing epithelial strand. After 4 d of ATRA treatment, TGF-beta2 was significantly upregulated in anagen HF in the dermal papilla (DP) and the dermal sheath, 7, and TGF-beta neutralizing antibody partially abrogated at RA induced hair growth inhibition. Real-time PCR confirmed a significant upregulation of TGF-beta2 transcripts in ATRA-treated hair bulbs. This study is the first to provide direct evidence that ATRA can indeed induce a catagen-like stage in human HF and suggests that this occurs, at least in part, via upregulation of TGF-beta2 in the DP. Therefore, topical TGF-beta2/TGF-beta receptor II antagonists deserve to be explored for the prevention and management of retinoid-induced hair loss.

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MemberMember
15
(@nemesisbrady)

Posted : 02/19/2017 12:45 am

I've had a lot of blood aork
the tsh flagged 5.6 and ultra sound showed thyroiditis it was dying too much bloodflow
tbis was in 2012 was put on levothyroxine went from 150-119 pounds in two months so stopped told I was healed lol

lip biopsy in 2011 was negative
blood Ana was only speckled one time in 2010 negative all the other times

my current rheum said its drug induced sjorgens won't show up on blood aork
has me on dairy gluten wheat egg free diet and low zinc and iodine showed up
ferritin is normal but low in my opinion 

my current symptoms are
dry scalp
dry eyes (plugs restasis xiidra and more I've tried)
dry nasal oassages
dry flaky nose and facial skin
rashes dermatitis rosacea like skin
sleep issues
 Cold hands feet
night sweats nightmares (think my ex gave me PTSD she was a bad person and my issues didn't help)
urticaria hives can't treat cause dryness

ive seen countless docs and more

I've tried every med and hate side effects my family is falling apart 

and I still get acne here and there 

I have to rub olive oil alllll over face
my refining is before bed water on face scrape nose with towel so dry 
olive oil air dry
cocobut oil on eyes and nose

They claim aim seb Derm not sure how when I have no oil at all
ans blepharitis they did say
i may try lipiflo 
my eyes are crusted stringy discharge worse in morning 

These two pictures are after a hair cut
mind u I didn't wash face notning
my skins so sensitive now

But it's so dry olive oil barely helps it 
was told not rosacea
then told it could be
then told its Seb derm
kp
acne
dermatagrpahisim hives
dermstitis
one said periorial yet not even on my
mouth area 

I feel screwed
i can't get under eye bag surgery because it drys eyes
and my eyes are extremely dry Shrimers showed 0
ive had v beam smooth beam after accuPAIN
ive takin that poison twice 
18/19 years old
ill be 28 next month 
dont feel like this will change 

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MemberMember
1803
(@guitarman01)

Posted : 02/19/2017 1:04 am

Sometimes I feel the dermatologist is as much to blame as the drug itself. If not more.

Was looking at this hormone. It's involved in retinoid metabolism

3-HSD

Biological processcellular response to jasmonic acid stimulus
steroid metabolic process
daunorubicin metabolic process
doxorubicin metabolic process
androgen metabolic process
retinoid metabolic process
bile acid and bile salt transport
bile acid biosynthetic process
oxidation-reduction process

Variousantidepressants, including theSSRIsfluoxetine,fluvoxamine,sertraline, andparoxetine, theSNRIvenlafaxine, andmirtazapine, have been found to activate certain 3-HSD enzymes, resulting in a selective facilitation of5-dihydroprogesteroneconversion into allopregnanolone. This action has been implicated in their effectiveness in affective disorders, and has resulted in them being described asselective brain steroidogenic stimulants(SBSSs).

34 minutes ago, Nemesisbrady said:

urticaria hives can't treat cause dryness

Have you tried Zantac or pepcid? They are h2 blockers. They shouldn't cause much dryness. Your shit don't look too bad actually. I mean you don't look sickly or anything. Seem to have good color in your skin. I'd try to focus on the positives and try to not let it consume you too much. Know it's hard though,especially when people got daily reminders of their sides

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MemberMember
2
(@triedmanythings)

Posted : 02/19/2017 2:33 am

What if I juice everyday?? Like beetroots ? That contains a bit vitamin A??? Is that a no-go??

I am affraid of eating carrots... Haven't Eat or juice for long time !

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MemberMember
299
(@macleod)

Posted : 02/19/2017 3:00 am

Not too sure about that. In the case of this teenage Indian boy who lost his night vision after a week of Isotretinoin. Protocol by the doctors was to discontinue use and supplement 20,000 iu of Vitamin A for 4-6 weeks "even if serum vitamin A reads normal". His night vision recovered completely. They proposed that people who have inherent deficiencies who take Isotretinoin develop the ocular side effects.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533586/table/T1/

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MemberMember
2
(@triedmanythings)

Posted : 02/19/2017 3:21 am

I am not on accutane now, been 3 years! Can I Then drink beetroots juice now and Then? 
Beetroot should nr healthy for your liver?

and what about coconut Oil :/ I know it has omega 3-6 ... Is that also a no-go... I just need to gain Weight after a among of lost Weight from a depression? :( and know coconut Oil is a good way..

sorry for all the questions.. :( 

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MemberMember
9
(@sacha_n)

Posted : 02/19/2017 3:32 am

@Nemesisbrady,
your symptoms are similar to mine (dry eyes, cold hands and feet) Your face pic looks like classic rosacea type 1 (mine is more severe)
Had night sweats some time ago, not anymore. (Maybe they're helpful, who knows?) Never tested for sjogren or thyroid (TSH in range).
Good thing you don't have hairloss and look younger than 28.

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MemberMember
15
(@nemesisbrady)

Posted : 02/19/2017 4:48 am

Yea thanks earlier to who said color don't look to bad
it's weird I'm extremely pale
lioe hands and my face just gets pink during sex shower heat nerves and exercise 
i also am housebound much of my days
ttied to go to bed at 1:30 woke up at 4am seeating
always have these night sweats now everyday 
not hot in here and in boxers dunno why

and I haven't tried those would those work? They gave me one med
and it's so drying he even said it def will but it'll help the hives

also afraid of vitamin a 
but I'm told to juice beets and all these 
I doubt doing all this will restore shrunk oil glands
but who knows 

I eat coconut oil here and there and use it cooking 
olive oil also

@sacha_n yea it's very weird
my skin looks different like that's when it flares up
i also have when I was using this moisturiser
and then days when it's just patchy and old acne marks laser marks u can see where it doesn't get red since v beam

I remember my hair was thinning for awhile the crown
i stopped wearing hats and all that
and that's when they gave me the levothyroxine 
my eyebrows fall out easily and eye lashes 
hair is dry 
but I'm thankful that hasn't happend and I'm so sorry to u that it has
i really hate what this drug has done
ans I feel I look really old
maybe this pic not so much I must have moisturizer in it 

I have very big bags under eyes from sleep issues
so bad I can provide pics but yea

and I have like lines under eyes and near mouth
pores are huge near t zone

 

Here's so pics 
:(

the first one I may have exfoliated on some
spots 

but u can see where it spares the pinkness jawline
shaving is almost impossible 

the second is typical spot it gets 
laser helped some spots 

ehhhh the last two excuse it
i feel I look 70 with those bags
not sure if it's thyroid causing them
but I've got them at 19
and I average maybe 3 hours solid sleep and then wake up every 2 hours and lay in bed about 13 hours lately

but for those wondering about tanning
i couldn't tan good either until recently 
I wouldn't say I tan where I want 
but there's hope u can tan
im a white Irish Italian 
my hands don't tan 
but that's my face with just the sun and I didn't go out much summer

but the main focus of last two is to show the pics
and how I feel Accutane aged me

To be be fair I haven't slept 7-9 hours straight in 10-11 years
so maybe that don't help
i was told sleep apnea before when I was 165
im 130 and adenoids small and tonsils
i was told I snore from people
but the machine dries out nasal passages :(
likw I feel like anything I do I'm screwed 

i I know it can be worse
just I'm light skinned so the pinkness and flaky and bumps are more pronounced in lighting in stores or outside 
and then I flush when anxious over this
rigjt now the dry eyes and sleep and skin stuff my main issues

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MemberMember
0
(@abi72)

Posted : 02/19/2017 5:17 am

http://www.mothering.com/forum/45-women-s-health/1091794-iodine-thread-3.html

Guys, many PFS claim to have recovered because of iodine.
Washer has used it for a while and recommends it.

https://www.scribd.com/doc/222400050/The-Secret-That-Doubles-Testosterone

I have seen that some of you have tried but not noticed a difference. We are not talking a few months here, 6 months plus is what is needed.
We have all learnt that the quick and easy approach in not going to work. Chopping and changing protocols every five minutes won't work either.
This protocol looks good for so many reasons - who wouldn't want to higher T naturally.
I read somewhere that accutane robs iodine out of cells but I can't find the article - has anyone seen it?

Ideally, for anyone who wants to give this a go - discuss with your doctor. Tell then you are DOING the protocol and you want to be monitored.
Get your bloods taken before and during protocol.

Healthy diets and exercise can only help.
Remember low carbs are recommended for PFS recovery.

If anyone has used iodine and wants to discuss it can they state dosage, duration, sides good and bad and co factors used.
It would be good if we got 2 or 3 guys who are willing to buy the supplements, start protocol at the same time and discuss and share progress.
Yes, we are looking at 6 months or more but how long have some of you been looking for answers!

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MemberMember
15
(@nemesisbrady)

Posted : 02/19/2017 5:21 am

@hatetane I was tested and my iodine urine levels were low normal like 45
they said to take kelp which I do now for 3 months
have to get rechecked
i did gain some weight back I noticed on a gluten dairy free diet? Not sure if it's bagels and frozen pizza I know bad but needed some food lol

onky difference I noticed
still cold and dry though
maybe not as many hot flashes?? When anxious I do
not really sure though
i do believe iodine is key
I will have to see

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MemberMember
0
(@abi72)

Posted : 02/19/2017 5:43 am

On 2/19/2017 at 6:21 PM, Nemesisbrady said:

@hatetane I was tested and my iodine urine levels were low normal like 45
they said to take kelp which I do now for 3 months
have to get rechecked
i did gain some weight back I noticed on a gluten dairy free diet? Not sure if it's bagels and frozen pizza I know bad but needed some food lol

onky difference I noticed
still cold and dry though
maybe not as many hot flashes?? When anxious I do
not really sure though
i do believe iodine is key
I will have to see

Hi and thanks for responding. I am not sure that iodine testing is that reliable. Also the home test is considered a bit lame as well.
Having said that I believe in as much testing as possible and always get a printout of you results. Doctors might say something looks ok
but do your own research and you will see that things may not be ok after all. T is a fine example - they give you a range but they don't consider your age. What young guy wants to have the same T as as 60 year old! I can tell you now that no average doctor understands the importance of estrogen in males. So take charge of your results and do your own research.

Cold hands and feet could be low B12.
Raised homocysteine in the brain is very serious and can be caused by low B12.
Also it is very well documented that accutane causes raised homocysteine.
I am not sure if it is possible to have normal B12 level but still have raised homocysteine (anyone researched this)
It is possible to test homocysteine levels so if you want to try and get your doctor to agree to it - print out an article reporting accutane and homocysteine association plus list all your side effects and you may get lucky.

Look up B12 and homocysteine and let me know what you think. There is a really good youtube film about low B12 - you might find it in my posts.

On 2/19/2017 at 6:43 PM, hatetane said:

[Removed Content]

 

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MemberMember
15
(@nemesisbrady)

Posted : 02/19/2017 6:00 am

@hatetane thank u I will look into this
i am on gluten free diet now so I lack b vitamins

my levels were normal but I'll bring this up

i think my t levels few years ago were actually sky high believe it or not like 900
i think it was the ssri and more messing with sex drive
because I got off those and my erections when by myself were still 60%-70%
but when I found a girl who I really loved and were
compatible she was very much into sex
my erections off the meds
meets least 80% better
maybe not like 18
but I do know anxiety plays roles and masturbation
i recently decided to
quit all that see if it helps
and maybe if I wasn't anxious over weight loss and this rashy flushing and dry eyes
i could actually perform
better again
i believe the erectile issues can improve they did for me
hope to god I didn't jinx myself
that girls gone now so I may have trouble down the road....
but needless to say
I believe sole
stuff
can get better
but this dryness no oil
gland issue I don't

what's everyone's symptoms
maybe we should all come together meet
up and go ambush docs and Accutane ppl for help

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MemberMember
47
(@walden-rev)

Posted : 02/19/2017 6:09 am

5 hours ago, guitarman01 said:

Some info on retinoid induced hair loss. Not sure if this has been posted yet. Someone mentioned on a forum this is reversible.

Towards dissecting the pathogenesis of retinoid-induced hair loss: all-trans retinoic acid induces premature hair follicle regression (catagen) by upregulation of transforming growth factor-beta2 in the dermal papilla.

Abstract

Diffuse hair loss ranks among the most frequent and psychologically most distressing adverse effects of systemic therapy with retinoids, which severely limits their therapeutic use even where clinically desired. Since the underlying mechanisms of retinoid-induced effluvium are as yet unknown, we have investigated the influence of the prototypic retinoid all-trans retinoic acid (ATRA, tretinoin) on the growth of human scalp hair follicles (HF) in culture. HF in the anagen VI stage of the hair cycle were cultured in the presence of 10(-8) or 10(-10) M ATRA. Compared with controls, hair shaft elongation declined significantly already after 2 d in the ATRA-treated group, and approximately 80% of the ATRA-treated HF had prematurely entered catagen-like stage at day 6, compared with 30% in the control group. This corresponded to an upregulation of apoptotic and a downregulation of Ki67-positive cells in ATRA-treated HF. Since transforming growth factor (TGF)-beta has been implicated as a key inducer of catagen, we next studied whether ATRA treatment had any effect on follicular expression. TGF-beta2 immunoreactivity was detected in the outer root sheath of anagen VI scalp HF. In catagen follicles, TGF-beta2 was also expressed in the regressing epithelial strand. After 4 d of ATRA treatment, TGF-beta2 was significantly upregulated in anagen HF in the dermal papilla (DP) and the dermal sheath, 7, and TGF-beta neutralizing antibody partially abrogated at RA induced hair growth inhibition. Real-time PCR confirmed a significant upregulation of TGF-beta2 transcripts in ATRA-treated hair bulbs. This study is the first to provide direct evidence that ATRA can indeed induce a catagen-like stage in human HF and suggests that this occurs, at least in part, via upregulation of TGF-beta2 in the DP. Therefore, topical TGF-beta2/TGF-beta receptor II antagonists deserve to be explored for the prevention and management of retinoid-induced hair loss.

So what are some TGF- Beta 2 antagonists?

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MemberMember
19
(@justdry)

Posted : 02/19/2017 7:55 am

1 hour ago, Nemesisbrady said:

@hatetane thank u I will look into this
i am on gluten free diet now so I lack b vitamins

my levels were normal but I'll bring this up

i think my t levels few years ago were actually sky high believe it or not like 900
i think it was the ssri and more messing with sex drive
because I got off those and my erections when by myself were still 60%-70%
but when I found a girl who I really loved and were
compatible she was very much into sex
my erections off the meds
meets least 80% better
maybe not like 18
but I do know anxiety plays roles and masturbation
i recently decided to
quit all that see if it helps
and maybe if I wasn't anxious over weight loss and this rashy flushing and dry eyes
i could actually perform
better again
i believe the erectile issues can improve they did for me
hope to god I didn't jinx myself
that girls gone now so I may have trouble down the road....
but needless to say
I believe sole
stuff
can get better
but this dryness no oil
gland issue I don't

what's everyone's symptoms
maybe we should all come together meet
up and go ambush docs and Accutane ppl for help

Sounds like you struggle with the same issue i have. Everything is fine except no oil on face. Mines just as red as yours looks in the pictures. Have to cover it before i can leave the house or see anyone. Struggling big time lately.

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MemberMember
15
(@nemesisbrady)

Posted : 02/19/2017 8:19 am

Yea mine gets worse if I touch it heat 
some days it's not as bad it's still pink but not inflamed I'm not sure
it's really annoying though 

heres recent blood aork well 8/12/16

may have more will look 
i know they checked iodine and b12

they checked a lot

not sure about my other hormones

im mainly extremely dry rashy sleep issues cold hands feet flushing anxiety depression 

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Following are more blood work
forgot this flagged not sure what it was

looks as if vitamin d is low normal
and dhea low normal
zinc was low
and iodine can't find that lab result
 

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MemberMember
1803
(@guitarman01)

Posted : 02/19/2017 9:40 am

3 hours ago, Walden Rev said:
So what are some TGF- Beta 2 antagonists?

T-flavanone might be one at first glance. looks like it might be in some expensive shampoos and serums.

trans-3,4'-Dimethyl-3-hydroxyflavanone, a hair growth enhancing active component, decreases active transforming growth factor beta2 (TGF-beta2) through control of urokinase-type plasminogen activator (uPA) on the surface of keratinocytes.

trans-3,4'-Dimethyl-3-hydroxyflavanone (t-flavanone) is a synthetic compound with hair growth enhancing activity that is effective against male pattern alopecia. t-Flavanone was designed as a derivative of astilbin, the active hair growth enhancing component of Hypericum perforatum extracts. This study was designed to elucidate the mechanism of hair growth enhancement by t-flavanone. We investigated the effects of t-flavanone on transforming growth factor beta (TGF-beta), a known catagen-inducing factor induced in hair papilla cells by male hormone. When t-flavanone was added to cocultures of human hair papilla cells and human keratinocytes, there was no change in the total level of TGF-beta2. However, levels of active TGF-beta2 were reduced, suggesting the involvement of t-flavanone in the activation pathway of TGF-beta2. In order to investigate the effects of t-flavanone on TGF-beta2 activation by human keratinocytes, we evaluated the level of active TGF-beta2 converted from the inactive form in t-flavanone-treated human keratinocytes. The amount of active TGF-beta2 was reduced compared with controls suggesting that t-flavanone suppresses the TGF-beta2 activation cascade in human keratinocytes. We then examined the activity of urokinase-type plasminogen activator (uPA), the rate-limiting enzyme in the TGF-beta2 activation cascade, in t-flavanone-treated human keratinocytes. We found that t-flavanone reduces uPA activity on the keratinocyte surface. t-Flavanone is a hair growth enhancing component that has a novel mechanism of action which suppresses TGF-beta2 activation, and thereby is expected to have therapeutic effects on other types of alopecia in addition to male pattern alopecia.

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MemberMember
1803
(@guitarman01)

Posted : 02/19/2017 1:16 pm

not sure if this has been posted as well. Seems like it could be a important study on the hormonal effects of accutane.

13-cis-retinoic acid competitively inhibits 3 alpha-hydroxysteroid oxidation by retinol dehydrogenase RoDH-4: a mechanism for its anti-androgenic effects in sebaceous glands?

Abstract

Retinol dehydrogenase-4 (RoDH-4) converts retinol and 13-cis-retinol to corresponding aldehydes in human liver and skin in the presence of NAD(+). RoDH-4 also converts 3 alpha-androstanediol and androsterone into dihydrotestosterone and androstanedione, which may stimulate sebum secretion. This oxidative 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSD) activity of RoDH-4 is competitively inhibited by retinol and 13-cis-retinol. Here, we further examine the substrate specificity of RoDH-4 and the inhibition of its 3 alpha-HSD activity by retinoids. Recombinant RoDH-4 oxidized 3,4-didehydroretinol-a major form of vitamin A in the skin-to its corresponding aldehyde. 13-cis-retinoic acid (isotretinoin), 3,4-didehydroretinoic acid, and 3,4-didehydroretinol, but not all-trans-retinoic acid or the synthetic retinoids acitretin and adapalene, were potent competitive inhibitors of the oxidative 3 alpha-HSD activity of RoDH-4, i.e., reduced the formation of dihydrotestosterone and androstandione in vitro. Extrapolated to the in vivo situation, this effect might explain the unique sebosuppressive effect of isotretinoin when treating acne.

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MemberMember
13
(@sclippers)

Posted : 02/19/2017 3:00 pm

I'll preface this by saying this will most likely be my last post ever on this subject. My parents and doc let me down, I absolutely regret having ever taken this. With age and perspective it's clear as day why the product appeals to so many people. The worst part is they're taking advantage of a very vulnerable age group, it was pure vanity on my end and insecurities. I also despise the fact doctors and vested interests 'objectively' present side effects %'s. It isn't you, just go in assuming there's a 50% chance you may have a serious short term or long term reaction to the meds and you'll more times than not make the right decision.

This is purely anecdotal of course. I'm 95% healed and I'm perfectly fine with whatever lingering side effects I have now. I'm not happy with my hair but that's life, I made a decision and in all honesty I'm way better for it. I'm now in charge of my health and I make it a point to act the part of an adult. If you can't take nothing away from this experience please make it that, you are your own caretaker. I'm 100% confident I could have waited it out and fixed my diet.

Some side effects went away with time but the joint+memory+hair issues didn't at least for me. I had a huge break through recently and I honestly can't attribute it to 1 thing so here's a list of things I have done:

Mental clarity and up and down feelings - PM me for that. I can't say here. But what I can say is regularly practicing yoga and meditation have netted huge gains for me.
4L water per day
Cut out all supplements. The biggest running scam there is that people who are looking for any answer succumb to every day. The only things I take supplement wise are ZMA (very noticeable benefits), Vitamin D and Fish oil. No B Vitamins or anything else. The body work as a unit and unless you're super deficient in something you'd probably be better off looking elsewhere.
Stress - I think the one thing everyone on here has in common is we felt like acne was taking a hold of our lives. It's the only reason you'd resort taking the drug willfully ignoring the laundry list of warnings and side effects. If you do suffer from hair loss I think this is one of the biggest reasons it continues to persist. And I'm not talking about traditional worry stress either, if you're suffering from back pain or are sick this can wreck havoc on your system. I don't know what accutane did to our bodies but I suspect it makes us more susceptible to the effects of stress and I've noticed this during exam periods and layoffs.

And I left this for last as I did reference a 'huge personal breakthrough.' For years I made a conscious decision to avoid all Vitamin A rich foods and I suspect that was a huge mistake. Over the past 6 months I've cleaned up my diet and start adding more plant based foods and juicing and the effect have been tremendous. Why should any of us avoid eating plant based foods? I was an idiot for ever doing so. If anything avoid eating over processed garbage and consume everything else in moderation.

How significant? Dry skin and brittle hair are a thing of the past. Even the joint issues! I sometimes wake up with my face as oily as it was during my teenage years.

Night and day difference my friends. I can't attribute my recovery to one thing but I can tell you doctors and DM's were a complete and colossal waste of time. And frankly they didn't care. They had no problem prescribing me this poison and did nothing to help me when I needed it.

I guess I'll stick around to answer any PM's but this is it for me. I'd like to thank oli girl and anyone else who who was compassionate enough to talk to me and try and help me out during my early years.

Am I jaded towards the medical community? A bit but at the end of the day this experience taught me to subscribe to self blame and self accountability first. It's something most adults lack in general as they're comfortable displacing blame and shifting the decision making process onto outside parties be it their significant other or doc.

Should you really get back surgery if you weren't in car crash?
Are the risks of chemo worth it?
Should you jump on thyroid medication if you're someone who already leads a very unhealthy lifestyle?

Don't jump to the first thing you're presented with in life. Take a deep breath and take some time.

You're allowed to be skeptical of what's going in your body and I hope Accutane has taught all of us that. There's obviously a time and place to seek professional help, but please take the time out to listen to your own body. It's what I did and it's worked wonders. It is after all your body and the changes are tangible, you'll know.

I got nothing but love for all of you and I hope you guys all the best in all of your future endeavors. If anyone ever wants to talk or shoot the shit PM me. I'm a very different mental space and it would be rude to not give back to a community that tried it's best to help me out when I felt hopeless.

Edit: I also posted this because it would be easy to not come back now that I'm recovered. There aren't too many feel good stories posted on here. I also debated making this post into a thread and fielding Q&A for a short period.

I also had some blood done work recently and all of my levels are not only in the normal range but at the top. Confusing but I'll take it. Especially my hormones+thyroid, they tanked right after I took accutane and stayed suppressed for years. There is hope and I think 'm one of the lone success stories.

It was a complete lifestyle change. That's my take home message.

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exitrade, Justdry, Chris16 and 15 people reacted
MemberMember
15
(@nemesisbrady)

Posted : 02/19/2017 3:09 pm

@sclippers

i agree reed with U on the medical field waste of time and not giving a shit

i just started juicing and more

zma will this help wth sleep??
and 4ltr of water does this help?

did u have dry eyes?? I feel so happy readings u wake up oily

how can I get oily skin and eyes back and sleep?

god bless u I'm sorry u have linger effects as well
i wish we all recovered
shame all this for acne because we wanted to fit in

now we don't fit in with ppl
least I dont

but I do on this
God bless everyone

Please se tell me how u got oily skin baxk
how long
did u take this poison twice???

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MemberMember
13
(@sclippers)

Posted : 02/19/2017 3:24 pm

19 minutes ago, Nemesisbrady said:

@sclippers

i agree reed with U on the medical field waste of time and not giving a shit

i just started juicing and more

zma will this help wth sleep??
and 4ltr of water does this help?

did u have dry eyes?? I feel so happy readings u wake up oily

how can I get oily skin and eyes back and sleep?

god bless u I'm sorry u have linger effects as well
i wish we all recovered
shame all this for acne because we wanted to fit in

now we don't fit in with ppl
least I dont

but I do on this
God bless everyone

Please se tell me how u got oily skin baxk
how long
did u take this poison twice???

I can't give you an accurate list of my side effects but this is what I remember:

Very annoying joint issues and aches
Dry eyes
Dry very brittle hair
No facial hair (100% back. I didn't think I Was capable of growing one until I looked in the mirror the other day and saw a full beard looking back at me.) From 20-27, nothing. I'm in my late 20's and I refuse to believe it's a sheer coincidence.
Some erectile issues but my hormones and thyroid were also shot. So were a lot of my other readings, I forget what exactly which sucks.
Some gut issues
Memory lapses
Incessant rumination. I couldn't break certain thoughts no matter what I did
Very strong up and downs, the highs and lows kind of stunted me as a person.

I'm probably forgetting a lot but I have next to no side effects left. I don't have any answers, I can only share my experience. I did so many things at once, and I simply did it for me not so much trying to cure my side effects. It was just a pleasant reaction, an unexpected one but one that I'll definitely accept haha.

If I can somehow find my blood tests from a couple of years ago, I'll post those coupled with my my new readings. My doctor was completely baffled. As was I to be honest.

Edit: I should also add that I've had various stages of recovery. Every single time I thought I was almost symptom free, more and more of my side effects would get better. I never thought I'd be here....

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MemberMember
15
(@nemesisbrady)

Posted : 02/19/2017 3:31 pm

So glad to hear this wow amazing
thank u soooooo much for posting this
i agree not a lot of success stories
i was literally at the end of my rope until I saw this
thank u man 
I'm 28
i have dry eyes scalp nose skin badly
and rashes
cold hands feet and sleep issues memory issues
and I get stuck in thoughts can't get out of them :(

ive been on dairy gluten wheat egg free diet 3-4 months
no change yet

@sclippers 
I'm really happy for u 
gives me hope I hope this goes away
it started at 19
second course did me in 

stress lack of sleep and staying in a room all day depressed anxious I'm sure doesn't  help me 

hope ow this dryness shit gets better

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MemberMember
13
(@sclippers)

Posted : 02/19/2017 3:39 pm

3 minutes ago, Nemesisbrady said:

So glad to hear this wow amazing
thank u soooooo much for posting this
i agree not a lot of success stories
i was literally at the end of my rope until I saw this
thank u man 
I'm 28
i have dry eyes scalp nose skin badly
and rashes
cold hands feet and sleep issues memory issues
and I get stuck in thoughts can't get out of them :(

ive been on dairy gluten wheat egg free diet 3-4 months
no change yet
 

@sclippers 
I'm really happy for u 
gives me hope I hope this goes away
it started at 19
second course did me in 

stress lack of sleep and staying in a room all day depressed anxious I'm sure doesn't  help me 

hope ow this dryness shit gets better

All of our bodies are unique which is why I try not to speak in absolutes. I still have cold hands and feet but I may have always had cold hands and feet. The accutane rabbit hole can go as long as you want it to. you can literally attribute break ups to accutane if you wanted to.

Experiment and jot down the changes. Ill be honest, I had no expectations and I simply did things to become a better athlete. It was never with the mindset of trying to recover from accutane, I didn't think it was possible.

Go for walks, be social, hit the gym and manage your stress. You still have a soul man. If you have an issue ask yourself if you can do something about it. If you can't let it be. If you can, work at it and give it time. Nothing happens over night.

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