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So my Telomere results pre Epitalon have came in.. I guess I have the telomere length of a 90 year old?......
On 12/13/2016 at 3:25 AM, Kynarr said:Arguing trivial details I see.
Yes, I did meet with an andrologist. I don't care much for the title, if anything she was pretty incompetent, as are most health professionals. I didn't learn much, I just now have access to prescribed Steroids if I so desire to shut down what's left of my natural T production. My reason for meeting with one is as simple as can be; I have low T and high SHBG/Estradiol.
I guessed for years that I had low T. Hypersomnia, low energy, always tired, joints prone to aching, dry skin, inability to gain muscle. Doesn't this bear much resemblance to Accutane sides? I'm through working on an Accutane toxicity theory. It makes more sense to focus on what's proven to be abnormal. I fully expect not a single person here has proper hormone levels. I fully expect none of you here gets decent results from going to the gym.
Main focus right now is the pituitary gland / thyroid. Again, pointing back to Iodine. I don't know yet for sure but I'd guess my hormone levels have improved in the past month. We'll know for sure soon enough. My goal is to avoid going on Androgel. It will be hard to know for sure because I'm playing a lot with Iodine, but I believe the pituitary gland is too screwed up to send proper LH signaling for T production.
Any of you have clear fluorosis signs on your teeth?
For the record, I have a very high libido. The only thing that ever affected this is depression and anti-depressants. That's just not a concern for me. Not sure why.
https://www.ncbi.nlm.nih.gov/pubmed/25721216
https://www.ncbi.nlm.nih.gov/pubmed/21103844
Thanks kynaar. I'm with you, tyroid and hormones. Your right to be cautious and experiment with one thing at a time.
You may feel better with iodine but like you said - you need to get tested pre and post experiment. Just don't assume T has been raised when actually something else might be at play. It truly would be great if iodine pushed your T up.
Improving progesterone to balance hormones may be worth looking at next - I am sure PFS guys found this.
https://draxe.com/10-ways-balance-hormones-naturally/
will supplements be the answer to accutane problems - probably not.
However it makes sense for everyone to adapt to a healthy lifestyle with good diet, exercise and supplementing.
Testing for any deficiencies also makes sense.
Anyone who has chemo has to undergo life changes .
The crime is that chemo supposedly saves a persons life if they have cancer - giving it to a kid who has acne, that they will most likely
grow out off, truly is a crime against humanity.
Derms should be prosecuted and struck off for prescribing accutane knowing how toxic and life destroying it is.
Doctors are seen as healers - what a joke!!!
When will you receive the results from your test after trying Epitalon? This telomere length is very worrying for an 18yo. The post a member had posted on Reddit was showing the telomere length of a 55yo as he was 49, 0.58 basis I believe based on your chart. Your score is a little bit lower, yet you're much younger. I'll read more into it, but depending on your results I too might get my length tested soon. Can't wait to hear more from you, and thank you for doing this!
Got my hormones tested yesterday. I added Estradiol and FSH myself to the list, but I couldn't abuse the additions too much.. ;). I'll get the results within a week or two.
Like most people here, I got low libido/ED/hairloss/gyno from the tane. Started smoking marijuana again. BAM, morning wood + spontaneous erections. Lets see how long this lasts. If someone could explain why marijuana works for curing this please let me know or point me to a reference.
7 minutes ago, UnicornExcrement said:Like most people here, I got low libido/ED/hairloss/gyno from the tane. Started smoking marijuana again. BAM, morning wood + spontaneous erections. Lets see how long this lasts. If someone could explain why marijuana works for curing this please let me know or point me to a reference.
It's because it's a DHT inhibitor. I get the same thing. Improved libido, less ED and better orgasm. There are 3 people on this thread who've made full recoveries using cannabis oil (RSO), although I have tried that and found I could get nowhere near the recommended dosage as I was absolutely smashed on a fraction of it. THC is the component which inhibits DHT, but unfortunately is also the component responsible for the 'stoned effect'.
Seems like people with tane sides/PFS etc do fall into two categories - those who respond well to things that RAISE DHT like creatine, and those that respond well to things that LOWER DHT.
I'm in the latter group, and sounds like you are too. I have very oily skin which is a symptom of high DHT, bloods confirm very high DHT (despite low T..), and I do well with eating lots of pumpkin seeds which also inhibit DHT. Some people do well taking 50mg/day zinc. I seem to get a headache doing this, but may look to try another brand.
On this note, who was taking Saw Palmetto, and how are you getting on?
So Monday I began taking MK-677, agrowth hormone secretagogue. Today is my 4th day of taking it and I'm noticing good results in the sleep department. Since I started taking it I no longer wake up multiple times in the middle of the night and I'm getting much deeper sleep, I'm going to continue taking it for the coming months.
Yesterday I began my trial ofAnastrozole, anon-steroidal aromatase-inhibitor. This is where the magic happens, my goal of taking this drug is to reverse 5AR inhibition. On my first dose yesterday of 1mg after dinner, I didn't notice much except that my testes tingled quite a bit on and off for the rest of the day. Upon waking up today I noticed something different, its crazy, after only one day of taking this drug I've noticed a change. I woke up SORE. I usually wake up with all my joint pain, and tendon pain and aching, but today, I woke up feeling some pain, and mostly SORENESS in these locations. The sore feeling is the type you get the next day after a really good workout the previous day, a feeling I haven't felt in a long time. I can only imagine that these locations are starting to get some healing after some estrogen blockage is occurring, and now my body is allowing itself to heal. Also I noticed today everything it a lot brighter, I'm more aware of my surroundings instead of going through my day in full autopilot gloom. I can only imagine what the coming weeks have in store for me. I think Anastrozole is going to be a golden ticket to my recovery.
This coming Saturday I'm going to also add a 5 week trial of TB-500 to speed up the healing process of joints/tendons, this is good timing for me because of all the time off I'm going to have for the holidays to really allow myself some time to relax and heal, and it's healing properties are really enhanced by the MK-677.
Also I'm going to do another 100mg 10 day trial of Epitalon again given my Telomere results, wouldn't hurt to add to my stack.
Can anyone say for sure that MK-677 is the way to go? I just looked up one distributor who wants $235 for 30 capsules, half of it is made up with L-Arginine by the way which I can buy alone for $20.
I can't justify paying that amount if it's just another supplement that's no better than the rest.
Any feedback would be appreciated 
I hope this helps someone with some of their symptoms. I've had cystic acne on my face & scalp since age 13. I took a 5 month round of accutane in the early 90's. It had not been out long. During the course of the treatment, I had hip joint pain, dry hair, skin, lips- carmex for the lips worked the best- I told the derm doc that the hip pain was the worst; he asked if it kept me from working, I said no, I push through; so he said then you are doing ok. After accutane, my complexion was clear for about 1 year; then the cystic acne came back, including on my scalp. Back on antibiotics, which I was trying to get off of and that's why I took the accutane in the first place. I didn't want to become antibiotic resistant, which I now am. I developed diabetes (unrelated to the accutane) and a couple years ago, I was having trouble keeping my blood sugar down; so I read the Wheat Belly Diet (anti-inflammatory diet) and it recommended eliminating wheat (gluten). Within 3 days of being on the diet, my acne completely disappeared. I was shocked. I vaguely remembered him mentioning that gluten can cause acne, but I've tried just about everything- and I dismissed it. It took a couple of weeks to get over the withdrawal symptoms but as long as I stay off the wheat, I have NO acne. It seems to trigger the oil glands, because my forehead will be shiney after eating a cracker or some bread. I have not missed bread at all, I dropped 10 pounds and my blood sugar leveled out.
During the accutane treatment, the hip pains in the joints hurt like bursitis. After treatment, It didn't disappear completely, but it did get better for a few yrs; gradually over the years, the same painhas come backagain. I take glucosamine sulfate & condroitin daily, which helps my flexiblity (you won't see results for about 3 months). I have a friend who takes hyaluronic acid supplements and swears by it for arthritis, so I'm going to try that as soon as my order gets here. She says it also makes her hair thick.
I have Meibomianitis, dry eye from the accutane; I get corneal abrasions just from rubbing my itchy eyes. The eye doc gave me systane for that, and it works better than all the other over the counter eye drops I've tried. I remember my eyelids itching so badly, I would pinch and bend them, and get the thick oil clogs out, they would feel better. Doc says they don't function now.
IBS symptoms started a few years ago; alternating constipation & exploding diarrhea. My GI doc put me on miralax *generic works fine* and my gut feels much better. I don't like feeling bloated after I take it (2 caps in a cup of water at night) but my problem is so much better, I'll deal with the bloat. She said ok to use it, it attracts water, so it won't hurt you like other laxatives.
Chronic sinusitis; I started getting severe sinus infections; every year more and more frequent; until I was only staying well about 3 weeks after a 10 day round of antibiotics before getting deathly sick again. Always starts the same; I get very dry in my nasal passages. Ocean does nothing to prime it. When I swallow, my soft palate will stick painfully to the upper nasal cavity. 3 days of that and I'm severely sick, sinus pain body aches, then green mucous plugs start clogging up nasal cavities and my nose swells shut. Then it goes to my lungs, and I cough up the nasty green mucous. Sinus doc roto rooted everything. But no change in frequency of infections. I started using Nasalcrom, Zicam. She told me I could lose my sense of smell permanently. I told her didn't matter, I had to do something. Cortisone sprays did nothing. Allergy tests came back mildly allergic to the usual things, pets, dust, pollen. I did lose a lot of my ability to smell. My son suggested I try grapefruit seed extract in a sinus rinse. I had tried sinus irrigation with saline daily with no relief; so I gave up and looked for a nasal spray with grapefruit seed extract; found nutribiotic nasal spray plus with the extract and xylitol, which using morning & night has cut my infections to about 2x a year. Just use it about an hour bf bedtime or you will drain so much, you will wake up choking. The Nutribiotic spray makes my nose run after the 2 sprays, but it only lasts about an hour.
The scalp acne has been a toughie. I tried Neem oil, and lots of other remedies; eliminating gluten was very helpful, but I still have small breakouts. Sore cysts if I eat gluten. I think Neem oil helped, but what I finally did was just put about 2ml of 70% alcohol on my scalp and rub it in every day. Itching has stopped, and as long as I do the alcohol, I have very few scalp pimples. My hair is thinning, but this has only been gradual and the past few years. I think it's age.
I sure hope something will give some of you relief. It is a lot to deal with, and mine is so minor compared to some of you. I'm glad I found this forum. No more acne, but still dealing with the effects of the accutane. My son took a 4 month round, and I'm praying he never has any of these problems. He says he never tans anymore, just splotches since he took the accutane as a teen. You all are in my prayers.
Make sure you get liver function tests before you start that as a baseline, and during it.
I personally don't trust much from most online sites when it comes to research chems.
Has anyone tested their DHT? I finall had mine tested but came back smack in the middle of the range.
7 hours ago, TrueJustice said:Can anyone say for sure that MK-677 is the way to go? I just looked up one distributor who wants $235 for 30 capsules, half of it is made up with L-Arginine by the way which I can buy alone for $20.
I can't justify paying that amount if it's just another supplement that's no better than the rest.
Any feedback would be appreciated
I purchased mine from one of the most trusted vendors irc.bio
but like I said, I think GH release will only help speed up some healing, the real magic is with Anastrozole.
48 minutes ago, ehohel said:I purchased mine from one of the most trusted vendors irc.biobut like I said, I think GH release will only help speed up some healing, the real magic is withAnastrozole.
Excuse my ignorance but where are you headed taking Anastrozole??
Isnt it used for treating breast cancer?
Whats your plan? How long will you be on it, what does it treat specifically for us tane victims?
On 12/16/2016 at 8:13 PM, TrueJustice said:Excuse my ignorance but where are you headed taking Anastrozole??
Isnt it used for treating breast cancer?
Whats your plan? How long will you be on it, what does it treat specifically for us tane victims?
Other people affected by 5AR inhibition have found it to reverse that, lowers estrogen without massive rebound, boosts testosterone. It's been posted here before but no one jumped the gun but me. Take some time out of your day and read every page about this guys experience on it, recovery was very quick.
[Edited link out]
ill stay on it for maybe up to a couple months or when I notice low estrogen side effects. For this first week or two I'll stick to 1mg, then drop down to 0.5.
On 12/16/2016 at 10:14 PM, mikez said:I've never heard it affecting 5AR or boosting testosterone ? I am confused by your rationale to try it. What did your blood Estrogens show?
[Edited link out]
by not allowing t to convert to estrogen your natural t production goes up.
Fin is another more commonly used drug with 5AR inhibition properties and some fin guys have found massive success with anastrozole bringing back normal t production. I posted that swolesource forum link of guy stating his experience with it and eventually fully recovering from post fin.
My estrogen was 37 which isn't horrible, but I believe it was actually at a higher baseline cause I took the test after taking Indol3carbinol + dim for 2 months prior to the test.
im only 3 days in and already starting to feel much better, in 3 days I'm feeling a lot better than many months of thousands of dollars on supplements and various nootropics. My muscles aren't aching as bad and it feels like they're actually being used instead of putting on a lot of stress on my joints.
@ehohelI'm unsure I see the purpose of going through anastrozole, and most importantly, I feel like you're trying a lot things at once, which while not necessarily bad for you, will make it hard to determine what does what. I tried CdG and DIM most recently which most likely reduced my E levels, and while I generally felt better on CdG due to what I believe was a combination of detoxification and hormone flushing, it didn't change my world. DIM has done nothing for me, I'm just taking it as PCT with LongJack after going on MK-2866.
I feel like natural compounds would be enough to clear excess E and allow more free T, unless you're boosting yourself with steroids or have actual proven levels of dangerously high E. My Estrogen was double yours in June, but I guess my focus has been more on my total T being low, even though for sure, my SHBG/E is abnormally high for my age.
My view is that maybe this helps you to have more free T, but I don't see how this would impact your total/free T production long term unless you consistently take aromatase inhibitors. If anything, I believe this goes to prove that we should focus more on WHY we don't produce as much T, which as far as I'm concerned, seems to point to the pituitary gland.
Btw, I'm curious how you get to spend so much time and $ as a 18yo. It's good that you do this though, definitely helps! By pushing our experiments, we'll soon find something that consistently works.
1 hour ago, Kynarr said:@ehohelI'm unsure I see the purpose of going through anastrozole, and most importantly, I feel like you're trying a lot things at once, which while not necessarily bad for you, will make it hard to determine what does what. I tried CdG and DIM most recently which most likely reduced my E levels, and while I generally felt better on CdG due to what I believe was a combination of detoxification and hormone flushing, it didn't change my world. DIM has done nothing for me, I'm just taking it as PCT with LongJack after going on MK-2866.I feel like natural compounds would be enough to clear excess E and allow more free T, unless you're boosting yourself with steroids or have actual proven levels of dangerously high E. My Estrogen was double yours in June, but I guess my focus has been more on my total T being low, even though for sure, my SHBG/E is abnormally high for my age.
My view is that maybe this helps you to have more free T, but I don't see how this would impact your total/free T production long term unless you consistently take aromatase inhibitors. If anything, I believe this goes to prove that we should focus more on WHY we don't produce as much T, which as far as I'm concerned, seems to point to the pituitary gland.
Btw, I'm curious how you get to spend so much time and $ as a 18yo. It's good that you do this though, definitely helps! By pushing our experiments, we'll soon find something that consistently works.
I'm going off the success stories of a few post fin guys. Since I believe 5AR inhibition is the main culprit of our sides, which both accutane and fin are 5AR inhibitors, and some of these guys found success with anastrozole. And I'm already noticing massive change. Read through that swolesource forum post.
6 hours ago, ehohel said:I'm going off the success stories of a few post fin guys. Since I believe 5AR inhibition is the main culprit of our sides, which both accutane and fin are 5AR inhibitors, and some of these guys found success with anastrozole. And I'm already noticing massive change. Read through that swolesource forum post.
Im glad you're getting some results. Problem I have is where to go next, you say anastrozole, others are saying Iodine, someone else says CBD oil, then there's talk of LDN, calcium d glucarate etc etc.......
Why don't I just take every supplement/drug ever made in the hope that one of them does the trick.
Then I'll just deal with all the other side effects that come my way.
Your E2 is a bit high actually. Naturally, if you are converting too much T, you are right, it should raise T. What dose are you using?
I got confused for a sec as here in Aus, we use different units. Itested 60 most recently, but its pmol/ml which is only 16 pg/ml. Your '37' I'm assuming is in pg/ml?
Thats great you are feeling better as its way easier to take than many other things.
Best of luck.
Also wondering, did you happen to try Clomid for any reason in the past?
1 hour ago, mikez said:Your E2 is a bit high actually. Naturally, if you are converting too much T, you are right, it should raise T. What dose are you using?
I got confused for a sec as here in Aus, we use different units. Itested 60 most recently, but its pmol/ml which is only 16 pg/ml. Your '37' I'm assuming is in pg/ml?
Thats great you are feeling better as its way easier to take than many other things.
Best of luck.
Also wondering, did you happen to try Clomid for any reason in the past?
No I have not tried Clomid, but this is supposed to be a lot more effective than clomid.
I tried anastrozole.. definitely felt better on it, probably by far most successful thing I've tried thus far, but did not last more than a few weeks after stopping
That's what made me positive this is hormonal like a yr ago. Weightlifting is probably the second most successful thing I've tried.. the more muscle you put on, the more permanent improvement you create
Currently trying Sustain Alpha. Extremely positive results so far.. I suggest you try that before pharmaceuticals
Hello! I would like to share my story and I would like to get some advice from some of you guys because I just don't know what to do anymore.
I took Accutane last year around this period for 5 to 6 months and my side effects were:
- loss of libido and erectile disfunction
- hair loss and change of texture
- emotionel numbness: i lost all my feelings
- depression
- brain fog: i felt brain dead all the time, couldn't think straight anymore,..
- loss of personality
- depersonalization and derealization
- suicidal
- I basically lived like a zombie for months
Before I took this drug I never had any health issues, definetely not mentally.. So that's why I think the Roaccutane was the instigator of everything..
My side effects were actually more psychological then physical. After several months all these things disappeared and life was great again. I did not do anything specific. I did some blood tests and also went to therapy. I took some vitamins (B and D) and supplements and I guess I just gave it some time. But now a month ago everything came back.
I've been searching through this forum for hours last year when the side-effects hit me. It was super difficult for me to understand all the scientific theories and I found it very confusing because I didn't understand anything.
I would like to ask the opinion of some of you guys because I don't know who could help me in this... Do you guys think that it's possible to somehow recover from all these sides and that 6 months later everything comes back? Or should I stop blaming Roaccutane for all my problems and look further? And did someone take antidepressants after Roaccutane? Because I'm now seeing a therapist again and he really wants me to go on them.. But the last thing I want is risking my health again by taking another drug..