Acne.org Products
8 hours ago, hatetane said:By a leading doctor, sorry I can't say who!!
The issue is how we deal with a probable drug induced side effect, similar to what we see with antidepressants and finasteride where effects can last for years afterwards. Do we wait for the body to recover with time or do we give more medication to reverse these changes (given that these problems are rare)?Giving Sildenafil (daily Cialis better) is quite reasonable , as the penis needs regular oxygenation and deterioration occurs if morning erections are lost. There are no risks with this.Low Oestradiol increases the risk of osteoporosis in the long term and should not be ignoredTreatmentwould involve "unlicensed" medication. Clomid would increase both T and Oestradiol and potentiate recovery of the pituitary, but opinions would differ as there are no trials or guidelines to help us here. Some doctors today feel totally restrained by guidelines.......................
Regarding Clomid. I was on Clomid in order to overcome the permanent accutane sides. But this Clomid makes you feel horrible. I only could take for a couple of days and then I stopped. Has anyone of you ever tried this for a longer period of time?
10 hours ago, hatetane said:I would suspect low as well as below range.By a leading doctor, sorry I can't say who!!
The issue is how we deal with a probable drug induced side effect, similar to what we see with antidepressants and finasteride where effects can last for years afterwards. Do we wait for the body to recover with time or do we give more medication to reverse these changes (given that these problems are rare)?Giving Sildenafil (daily Cialis better) is quite reasonable , as the penis needs regular oxygenation and deterioration occurs if morning erections are lost. There are no risks with this.Low Oestradiol increases the risk of osteoporosis in the long term and should not be ignoredTreatmentwould involve "unlicensed" medication. Clomid would increase both T and Oestradiol and potentiate recovery of the pituitary, but opinions would differ as there are no trials or guidelines to help us here. Some doctors today feel totally restrained by guidelines.......................This iswhy talking with Dr goldstein, Dr Shippen, Dr jacobs and other might be useful. I don't know why they don't
record and share their findings.
We definitely need more data!So you had HGH, SHGB, Adiol - G and many other tests done - have you ever shared these results?
I don't think my endocrinologist tested those things. I'd be happy to get another test next year and if there's a trend amongst us that indicates those things are low, great we've found something common that we can work on.
It won't be till next year though, this year all the colonoscopy, endoscopy, blood tests for this & that, the multiple tests for copper etc when at was the big thing to focus on. The ultrasounds on the liver, the multiple liver flushes - All these things that took time, cost money amounted to jack shit for me in the end.
You can see how I might be reluctant to race out and do an do any more tests at this stage.
On 11/23/2016 at 7:47 AM, TrueJustice said:When you google "Pituitary supplement" heaps of stuff comes up.One in particular is Raw Pituitary glandular by Swanson - that looks interesting.
In terms of testing, been there and done it - nothing conclusive ever comes from it. Waste of time and money - we are on our own with this mess constantly self diagnosing and experimenting.
Thats the reality for me after 20 years. It's like we've been left with Parkinson's or something which as you know there is no cure for....
Those 'glandular' supplements are also a waste of time and money, with zero evidence. I thought you were talking about things like Clomid.
On 11/23/2016 at 4:14 AM, ehohel said:MK-677 (growth hormone secretagogue) (I will most likely be trying this soonish)
RAD140 (This compound provides is being studied for neuroprotection as well; an important neural action of endogenous androgens that is relevant to neural health and resilience to neurodegenerative diseases, and to be as effective as testosterone in reducing cell death induced by apoptotic insults.) Sounds interesting
Be careful. I follow the post history of a former vendor of SARMS (and related compounds), and recently, there have been legal/payment processor pressures that have caused many reliable suppliers to pull out. No one really knows who to trust anymore. Most MK-677 on the market is impure because it is pricey to synthesize. (Start reading at "Fake MK-677.") If one vendor denies an impure batch from a lab, then the lab just sells it to some other vendor for unsuspecting buyers to eat up, lol. Even Certificates of Quality are meaningless in the absence of more information. If you are determined to buy it anyway, this thread may have some more useful information.
That aside, I'd try things like RAD140 and LGD-4033 as a last resort. Here is an account of someone who suffered from enduring fatigue and sexual dysfunction after messing with LGD-4033. Here is an account of someone who got their blood tested before RAD140 and then while on RAD140. SARMS suppress your testosterone. It could be the case that most people bounce back, but what is the point of messing with a compound that only gives short term benefits at the expense of potential long-term issues?!
On 11/23/2016 at 4:14 AM, ehohel said:Anastrozole (aromatase inhibitor)
If you suffer from cognitive impairment, this should be on the "do not touch" list, right up there with Accutane and Propecia. Aromatase inhibitors are literally more associated with post-chemotherapy cognitive impairment than chemotherapy itself. As absurd as that sounds, it appears true: "Using a math formula, the researchers determined that hormonal therapy seemed to be the only factor linked to cognitive problems. . . .Still, a small number of women continue to have problems for a year or more after treatment ends." Once you start messing with hormones and SARMS, you REALLY have to know what you're doing.
I have a little list for you guys , take a wild guess which DRUG is on top of the list ....
http://prescriptiondrugs.procon.org/view.resource.php?resourceID=005528
On 11/24/2016 at 7:09 AM, ACCUiTy_drANE said:Be careful. I follow the post history of a former vendor of SARMS (and related compounds), and recently, there have been legal/payment processor pressures that have caused many reliable suppliers to pull out. No one really knows who to trust anymore. Most MK-677 on the market is impure because it is pricey to synthesize. (Start reading at "Fake MK-677.") If one vendor denies an impure batch from a lab, then the lab just sells it to some other vendor for unsuspecting buyers to eat up, lol. Even Certificates of Quality are meaningless in the absence of more information. If you are determined to buy it anyway,this thread may have some more useful information.
That aside, I'd try things like RAD140 and LGD-4033 as a last resort.Here is an account of someone who suffered from enduring fatigue and sexual dysfunction after messing with LGD-4033.Here is an account of someone who got their blood tested before RAD140 and then while on RAD140. SARMS suppress your testosterone. It could be the case that most people bounce back, but what is the point of messing with a compound that only gives short term benefits at the expense of potential long-term issues?!
If you suffer from cognitive impairment, this should be on the "do not touch" list, right up there with Accutane and Propecia. Aromatase inhibitors are literally more associated with post-chemotherapy cognitive impairment than chemotherapy itself. As absurd as that sounds, it appears true: "Using a math formula, the researchers determined that hormonal therapy seemed to be the only factor linked to cognitive problems. . . .Still, a small number of women continue to have problems for a year or more after treatment ends." Once you start messing with hormones and SARMS, you REALLY have to know what you're doing.
Interesting info thanks. Yeah I'll probably give MK-677 still a try from a trusted vendor and take my chances with impurity for a month. But probably after I try LDN. If I find some success with MK-677 I might just give HGH a shot at lower doses.
Yesterday I have finished my Epitalon experience. First bottle was the NA version, 10mg/daily second bottle was the N version 10mg/daily. Took no break, went directly for 20 days.
I think that I have slightly more energy in the day time. (Maybe like a 10-20%) increase. I think I can assume this is because of the better sleep quality. Other than that I haven't really noticed anything else like decrease in inflammation from a strengthened immune system. Unless telomere lengthening takes multiple weeks or months after dosage to effect the majority of your cells/glands/organs. I don't think I will use it again, unless once my Telomere results come in (1-2 more weeks) and they are obnoxiously short for my age.
Has anybody has adverse reactions to putting antioxidants, specifically vitamin a, on their face? I'm looking at using olive oil to fight the severe dryness I still have but it has lots of vitamin a in it, which is usually okay, but is it okay for us? Especially since I have severe facial blushing and extremely thin skin?
5 hours ago, helpmeoutbuddies11 said:Has anybody has adverse reactions to putting antioxidants, specifically vitamin a, on their face? I'm looking at using olive oil to fight the severe dryness I still have but it has lots of vitamin a in it, which is usually okay, but is it okay for us? Especially since I have severe facial blushing and extremely thin skin?
I don't want to steer you away from Vit A per say but why not try Vit E. You can get it in a lotion easily enough and it is known ( E Vit ) to be an antidote to Vit A toxicity which essentially is what we are dealing with!?
On 11/23/2016 at 5:02 PM, hatetane said:Those Fin guys have every test under the sun and some of them do recover.
I know side effects of accutane are many and varied but if you have sexual side you have all your sex hormones tested.
Can someone tell me - is it fear, lack of doctor support, self denial or just pure laziness?
All the research papers I read say that androgens are not affected by Finasteride and accutane; the recent PFS report also says this.
But it just isn't right, Longterm testosterone is greatly decreased and for some below a healthy range.
I repeat myself - most of you are within range although on the lowish side so your doctor says it ok. Well no it isn't because it is having a knock on effect on all your other hormones. GET TESTED!
True justice: Dubya (lasting sides and this forum) had clomid treatment. I don't know what his full protocol was but overall I don't believe
it worked for him.
Hey buddy
The thing is that the results I'm getting are not getting me anywhere. No libido since 10 years. Just needed to stop having sex with my gf because I was so empty with no emotions that got soft... 3rd time since 12 days of our so-awaited holidays..........
Spent good part of last 10 years visiting doctors and testing myself. Nothing relevant has been found as yet.
Yes, I had very low free testosterone and very low DHT.
Did a clomid treatment, took shots of testosterone, took dhea....it's all poitnless. Had scores over the top after clomid yet still was as miserable sexually as ever.
Now I have mid-lowish T - feel the same as ever.
Obviosuly, I'm all in the "get tested" camp however it's so fucking depressing that with all that money and time invested it's not getting anywhere...
Let me give you an example. Nowadays the only result which looks dodgy is my catecholamin test (btw @hatetanespoke about dopamine test - that's this one).
Posted the results here. [Edited link out]
Tried to find a doctor who would be interested in this case and willing to spend some time thinking about it. Every single one didn't want my case.
Eventually found an experienced scientist with whom I'm working but hopefully you see my point.
That said, I'm willing to take any test that is needed and get any treatment necessary to get me sex drive back. Fortunatey, money's not an issue and can spend a lot if this will get my life back.
Any suggestions?
Btw, as someone was discussing this above - did an MRI of my pituitary as well and it's perfectly fine.
5 hours ago, Nick Ryan said:
Great post - all those side effects even 20 years on ring true!!
I will shortly in consultation with my gastroenterologist be doing a 'poo transplant' to finally I hope fix all stomach issues. I honestly believe it's not possible to benefit from any supplement or drug whilst stomach lining is screwed.
I also believe other organs cannot sufficiently heal whilst stomach is in poor health, we just aren't absorbing things correctly.
Its prob the first thing that got fucked up when I took this shit poison 20 years ago. It's high time I fixed gut health and I'm hoping after that my organs will start to heal too once I fix it.
@Nick Ryan
I see similarities in your signature to my condition. And also in your engineer's mindset.
FYI: White rice is fundamental to my diet. LDN was the lynchpin of my recovery.
Carry on!
On 2016-11-24 at 2:48 AM, TrueJustice said:Great post - all those side effects even 20 years on ring true!!I will shortly in consultation with my gastroenterologist be doing a 'poo transplant' to finally I hope fix all stomach issues. I honestly believe it's not possible to benefit from any supplement or drug whilst stomach lining is screwed.
I also believe other organs cannot sufficiently heal whilst stomach is in poor health, we just aren't absorbing things correctly.
Its prob the first thing that got fucked up when I took this shit poison 20 years ago. It's high time I fixed gut health and I'm hoping after that my organs will start to heal too once I fix it.
Acumulative dosage? Your stomach issues are more likely related to previous antibiotics use.
Thank you guys and Hatetane as usual for your information and support. I met with my family doctor this morning and discussed with her my motivation for further hormonal testing. She gave me the *you must be crazy* eyes and we ended up in a debate whereas she believes my *issues* are either mental or inherited. It sucked a bit as I could see we're on totally different spheres, but I nevertheless understand how hard it would be for her to doubt her whole profession based on how a little pill could ruin me as much, so.. well, let's just say I won't go there again for support.
She referred me to andrology specialists. I'll meet with one in January and see from there what might be wrong with my hormones. I'll have to find new avenues for non-hormonal related testing as my family doc seems unwilling to test as I've already had *too many* tests done just 6 months ago. Guess I'll have to go private and pay the price for quality service. I hate to go through this, but I trust that as I move forward I will find professionals and experts who are willing to consider my issues as true and treat me accordingly.
Going back to Iodine, little story to share.
I went to the spa yesterday and thought that I might as well use this occasion as an excuse to dose more Iodine, seeing as I've definitely been exposed to loads of Chlorine. I didn't take this much, probably around 10mg, but I felt like a totally different person for the next few hours. Crazy energy levels, much more emotional and talkative, and somewhat sharper and more vibrant than usual. Was also extremely tingly, like impossible to touch me (was with a friend and uh.. yeah). It was something I'm not at all used to anymore. I haven't experimented much with Iodine since discussing it here a month ago, besides taking 1-2mg every so often, but I maintain my belief that more people should attempt Iodine protocols and megadoses. You guys here are now talking about the Pituitary Gland, which Iodine very much affects too. I feel there's just a lot of things Iodine and Accutane share. It might not be a complete cure, but I figure there are merits to trying more Iodine. More of you ought to try it.
@comishcfI've stopped taking CdG while I'm on my Ostarine trial. There is also one part about CdG that I didn't particularly like, and it's that ~10% of it is calcium (12.5% where I source it from actually). Megadosing 3g to 6g a day for 2 months helped me a lot I feel, and I miss it right now, but I believe that was too much Calcium for my long term good. For this reason, I find Glucuronolactone to be a very attractive alternative. The issue is there is little information available on it. I THINK it acts just about the same as CdG, but I'm no pro at it and honestly I've no idea how to be sure of it.
The three? times I tried glucuronolactone, I took the same 3g dose and had the same effects as with CdG. Acne coming back every time without fail too.
-
In regards to my MK-2866 (Ostarine) trial, I'm now 20 days in. Strength has gone up as expected from eating more, and I have 0 sides, except the same side fat tingling and bloating I've had since day one. I hate it, and I feel it might have to do with some form of Estrogen dominance while I'm on it. Pretty sure I gained fat. I can't wait to be done honestly.
The more I read up on SARMs, the more worried I am. They're apparently derived from the same compound that makes up Finasteride, a 5-ARI. Seems to be that the reason they're not considered to be proper steroids is just because they prevent DHT related issues. Doesn't sound very good for a post-Accutane candidate.
14 hours ago, Kynarr said:Thank you guys and Hatetane as usual for your information and support. I met with my family doctor this morning and discussed with her my motivation for further hormonal testing. She gave me the *you must be crazy* eyes and we ended up in a debate whereas she believes my *issues* are either mental or inherited. It sucked a bit as I could see we're on totally different spheres, but I nevertheless understand how hard it would be for her to doubt her whole profession based on how a little pill could ruin me as much, so.. well, let's just say I won't go there again for support.
She referred me to andrology specialists. I'll meet with one in January and see from there what might be wrong with my hormones. I'll have to find new avenues for non-hormonal related testing as my family doc seems unwilling to test as I've already had *too many* tests done just 6 months ago. Guess I'll have to go private and pay the price for quality service. I hate to go through this, but I trust that as I move forward I will find professionals and experts who are willing to consider my issues as true and treat me accordingly.
I didn't think you would find it easy. So frustrating I know! Referring doctors to this forum is a waste of time. Unless they have a personal investment they just don't have the time or inclination. What might help is finding a group of accutane suffers from your area(unlikely) or your country.
It's shocking that there is not an accutane action group anywhere in the world that I know of.There was one in Ireland/UK at one time but no more.
So only suggestion I have is to print of complete histories/stories of this forum and others and leave them with your andrologist to look at.
He won't be able to read them there and then but ask him to give you feedback once he has read them. Also take a copy of Dr Healy's report.
Try being tougher with doctors - don't take no for an answer. This is your life and you have a right to be tested.
Also apply to your local/national health provider for freedom of information act to get a report on:
All reported affected side side effects of accutane.
All side effects that people have attributed to having taken accutane.
Any legal action taken and the outcomes including pending cases.
How many people reported sexual side and anything else specific you want to know about
Anything else you can think of just add it in.
I though this would be a difficult process it was so easy - just a quick email.
Will share when i get the result within the next couple of months.
You can see that if much info come to light it may give some the opportunity to take legal action.
Which would in turn highlight the dangers of accutane.
Kynarr - At least you tried - thanks
On 11/23/2016 at 5:48 PM, Roland1968 said:Regarding Clomid. I was on Clomid in order to overcome the permanent accutane sides. But this Clomid makes you feel horrible. I only could take for a couple of days and then I stopped. Has anyone of you ever tried this for a longer period of time?
Thanks for your response.
On 11/23/2016 at 8:00 PM, TrueJustice said:I don't think my endocrinologist tested those things. I'd be happy to get another test next year and if there's a trend amongst us that indicates those things are low, great we've found something common that we can work on.It won't be till next year though, this year all the colonoscopy, endoscopy, blood tests for this & that, the multiple tests for copper etc when at was the big thing to focus on. The ultrasounds on the liver, the multiple liver flushes - All these things that took time, cost money amounted to jack shit for me in the end.
You can see how I might be reluctant to race out and do an do any more tests at this stage.
I know it's tough and a lot of you guys have worked incredibly hard to find answers. We got to keep fighting though and what really makes me sad is that no one is trying to get accutane of the market. I know some have tried but it defies belief that anyone would prescribe this obscenity to
anyone especially young innocent teenagers - it's an utter outrage!
An easy email requesting freedom of information regarding accutane might bring to light something we can work with.
You live in Australia - this would really be helpful.
I have made the request in the UK.
Accuity in the USA?
If kynarr does it in Canada who knows what we will discover.
There is power in knowledge.
Apologies for the rants recently, I just want to find a way forward.
We do know tests take so far have revealed something, even if it hasn't yet given us the full picture.
I believe that we have to look into deeper testing. Has anyone had pregnelonone or progesterone tested for instance?
We know:
High brubilin (sp) = liver
High cortisol which will lead to low cortisol
Low Vit D
Lowered T
Low E(fact) but many report high as well especially Fin guys.
High urine output with high dopemine result(fact)
So to say test results yield nothing isn't quite true.
I ask that everyone, even if you have done it before, to share your test results to date.
Anyone had a fullsex hormone panel test done? Please share these results.
Thanks everyone.
It's interesting isn't it the frustration we experience in talking to the average doctor.
How do they explain though when Accutane pops up on those most dangerous drugs list at No.1 no less!!?? And how do they explain all the millions of dollars given out by Roche in lawsuit payouts??
I mean is is it really hard to fathom that the rest of us lucky enough to not need our bowel removed might be suffering from depression or fatigue or any number of health conditions!?
the mind boggles.....
On 11/23/2016 at 8:00 PM, TrueJustice said:I don't think my endocrinologist tested those things. I'd be happy to get another test next year and if there's a trend amongst us that indicates those things are low, great we've found something common that we can work on.It won't be till next year though, this year all the colonoscopy, endoscopy, blood tests for this & that, the multiple tests for copper etc when at was the big thing to focus on. The ultrasounds on the liver, the multiple liver flushes - All these things that took time, cost money amounted to jack shit for me in the end.
You can see how I might be reluctant to race out and do an do any more tests at this stage.
I know it's tough and a lot of you guys have worked incredibly hard to find answers. We got to keep fighting though and what really makes me sad is that no one is trying to get accutane of the market. I know some have tried but it defies belief that anyone would prescribe this obscenity to
anyone especially young innocent teenagers - it's an utter outrage!
An easy email requesting freedom of information regarding accutane might bring to light something we can work with.
You live in Australia - this would really be helpful.
I have made the request in the UK.
Accuity in the USA?
If kynarr does it in Canada who knows what we will discover.
There is power in knowledge.
Apologies for the rants recently, I just want to find a way forward.
We do know tests take so far have revealed something, even if it hasn't yet given us the full picture.
I believe that we have to look into deeper testing. Has anyone had pregnelonone or progesterone tested for instance?
We know:
High brubilin (sp) = liver
High cortisol which will lead to low cortisol
Low Vit D
Lowered T
Low E(fact) but many report high as well especially Fin guys.
High urine output with high dopemine result(fact)
So to say test results yield nothing isn't quite true.
I ask that everyone, even if you have done it before, to share your test results to date.
Anyone had a fullsex hormone panel test done? Please share these results.
Thanks everyone.
34 minutes ago, TrueJustice said:It's interesting isn't it the frustration we experience in talking to the average doctor.
How do they explain though when Accutane pops up on those most dangerous drugs list at No.1 no less!!?? And how do they explain all the millions of dollars given out by Roche in lawsuit payouts??
I mean is is it really hard to fathom that the rest of us lucky enough to not need our bowel removed might be suffering from depression or fatigue or any number of health conditions!?
the mind boggles.....
Too true. You would think that a young man walks in and says he has serious sexual side that an y doctor would step through every hoop to help that kid. That poor kid goes away and pos commits suicide - do they give a f*** do they hell!
Did you know Fin guys even now get the same response!!
So I've been on nsi-189 for about a month now and while I have seen some vague improvements, little else has changed. My libido came back out of nowhere for a day or two a week ago, but then went away.
Honestly, I don't care how many people would be devestated, but I'm not going to live a whole life either finding bullshit supplements and doctors who won't help, and I sure as hell am not the kind of person who just blindly accepts negative change for a lifetime either.
On 11/26/2016 at 5:28 AM, cnb30 said:So I've been on nsi-189 for about a month now and while I have seen some vague improvements, little else has changed. My libido came back out of nowhere for a day or two a week ago, but then went away.
Honestly, I don't care how many people would be devestated, but I'm not going to live a whole life either finding bullshit supplements and doctors who won't help, and I sure as hell am not the kind of person who just blindly accepts negative change for a lifetime either.
Good!! Be strong and get yourself back to college next year.
Eat healthy and exercise.
do you think you are strong enough to demand your doctor to order complete blood tests like the one Kynarr wanted to get?
We do need to get as many people to have these tests as possible but most doctors jut won't agree to it!
QUOTE :
The physiological loss of sodium occurs when energy metabolism fails, as in diabetes, hypothyroidism, hyperestrogenism, and starvation. What these conditions have in common is an increased level of free fatty acids in the blood. Increased free fatty acids impair the use of glucose. The consumption of carbohydrate, like an increase of thyroid hormone, insulin, or progesterone, increases the retention of sodium; fructose is the most effective carbohydrate (Rebello, et al., 1983).
[removed]
Anyone looked into this?
There has been some talk about fundraising scientists to look our case. What happened to that idea? I can't see them working for charity on this. We can try to do our own research, but I feel that it isn't taking us anywhere. Atleast it's taking too much of time and in best case someone gets his symptoms cured, but I don't think that's enough. The pharma industry needs to pay somehow for ruining our lives. Because of that we need scientists to work on this sooner or later and I rather choose the sooner option.