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15 hours ago, TrueJustice said:Just remember folks - as soon as you start looking at prescription medicine everything comes with its own list of side effects.But we're fucked cause supplements don't work so what choice do we have but to look at more drugs to get us out of this mess!
Thanks for posting - I may have to look at some of that stuff for brain fog - my career is at stake if I don't too!!!
More synthetic drugs NO thanks , the next time I take another prescription drug IS the day I die FACT.
2 hours ago, Gladiatoro said:More synthetic drugs NO thanks , the next time I take another prescription drug IS the day I die FACT.
Well, not all prescription drugs are the same... for exampleVSL#3 DS is on prescription and basically it's very powerful probiotic. Why prescription is needed for that is beyond me, maybe they(I leave to you to figure out who "they" really are) think that leaving OTC products that can really make a difference is dangerous(I mean getting people healthy? WTF, that would mean lose cash for pharma companies) so it's better to leave OTC only weak, not so effective probiotics.
Although I understand what you wanted to say. I agree over 90% of prescription drugs are prescribed unnecessary. But I don't thjink they are "bad", because even those synthetic have they place. Bad are pharma and doctors that push those drugs for those that don't need them.
53 minutes ago, Umas said:Well, not all prescription drugs are the same... for exampleVSL#3 DS is on prescription and basically it's very powerful probiotic. Why prescription is needed for that is beyond me, maybe they(I leave to you to figure out who "they" really are) think that leaving OTC products that can really make a difference is dangerous(I mean getting people healthy? WTF, that would mean lose cash for pharma companies) so it's better to leave OTC only weak, not so effective probiotics.
Although I understand what you wanted to say. I agree over 90% of prescription drugs are prescribed unnecessary. But I don't thjink they are "bad", because even those synthetic have they place. Bad are pharma and drugs that push those drugs for those that don't need them.
Have you tried DS? I have the regular VSL coming in, and I was just curious if there's any major difference.
1 hour ago, ehohel said:2 hours ago, Umas said:Well, not all prescription drugs are the same... for exampleVSL#3 DS is on prescription and basically it's very powerful probiotic. Why prescription is needed for that is beyond me, maybe they(I leave to you to figure out who "they" really are) think that leaving OTC products that can really make a difference is dangerous(I mean getting people healthy? WTF, that would mean lose cash for pharma companies) so it's better to leave OTC only weak, not so effective probiotics.
Although I understand what you wanted to say. I agree over 90% of prescription drugs are prescribed unnecessary. But I don't thjink they are "bad", because even those synthetic have they place. Bad are pharma and drugs that push those drugs for those that don't need them.Have you tried DS? I have the regular VSL coming in, and I was just curious if there's any major difference.
No, VSL DS is hard to get where i live. I only tried regular VSL. Right now I will try Atrantil because I have diagnosed SIBO and I will try to convice doctor to prescribe me LDN. I am also looking into iodine but I'm trying to change only one thing at a time - so I can discover what really can help.
BTW Something interesting to read
http://www.gidoctor.net/client_files/file/Naltrexone-Side-Effects-and-Efficacy-in-GI-Disorders.pdf
It concludes that Naltrexone is not so risk free as I thought before, but at the other hand it can really help.
> It concludes that Naltrexone is not so risk free as I thought before, but at the other hand it can really help
Considering how much difficulty sick people have merely grasping the concept of gradual dosage titration, much less correctly implementing it, plus the potential for side-effect misattribution, I'm skeptical of the gross side effect numbers.
I have yet to see anyone say: "I halved the dose whenever there was trouble, but just couldn't manage to gradually build up to the normal dosage range over a few months. I ran into a side-effect wall every time."
On 10/25/2016 at 2:22 AM, macleod said:This was an interesting read. I don't have complete sexual dysfunction but I did lose probably around 20% of my libido (only took tane for a month), however this deficiency mentioned lactic acid. And I find that interesting because I basically have no lactic acid sensation during exercise anymore and the muscles work to failure, not fatigue. I can run miles and miles and don't know when enough is enough, but only after years of trial and error, through stress buildup sensations in the bones and tendons, and common sense judgement. I can also lift for super sets (5-6) usually and several reps (15-20) and it is near impossible to reach a "pump" (blood flow peak) in the muscle. Needless to say delayed onset muscle soreness is completely different as well. Sometimes 48-96 hours later. Not the norm.My question is, since I clearly had none of this pre-accutane, was this an underlying issue or did the drug cause this deficiency?
Does anyone else out there have similar symptoms?
Also, this is just one of what? 100 symptoms. One of the least of my worries, but if it helps in tackling the others as well, I'll try and focus on it.
Hey I have never spoken to you before, but it's impossible for any of this to occur from a month of accutane. Sorry to hear about your sexual dysfunctions though, I hope it resolves! I doubt you have hundreds of symptoms from a month of accutane. I'm sorry to say but you might be an undiagnosed hypochondriac:/ you seem to be analyzing way too much much. Maybe you don't get as sore or fatigued because you have been exercising for years. Anyway, good luck buddy
13 minutes ago, JohnSmith21 said:Hey I have never spoken to you before, but it's impossible for any of this to occur from a month of accutane. Sorry to hear about your sexual dysfunctions though, I hope it resolves! I doubt you have hundreds of symptoms from a month of accutane. I'm sorry to say but you might be an undiagnosed hypochondriac:/ you seem to be analyzing way too much much. Maybe you don't get as sore or fatigued because you have been exercising for years. Anyway, good luck buddy
You better believe it. Good luck with your third course fam!
Thank you, thank you so much. After reading many post about the terrible side-effects of roaccutane. I'm gonna stop with it. I only took 2x 20 mg. The reason is that I don't want my life to be ruines by this so called wonder drug. I'm 17 and there are other less effective and slower ways to get a good skin. I hope you will find a way to lose your depression. But thank you so much for sharing your story. I have learned from it. Thank you!
On 10/29/2016 at 6:55 PM, Warrah said:Hi,
You could try using a daily regimen of washing your face with a sulphur soap (make sure to pick one with good reviews/ingredients, I use 'keep it clean' a 10% sulphur soap) and afterwards moisturize with unrefined raw shea butter.After accutane one of the problems I developed was progressively worsening rosacea and dermatitis on my face and scalp. For a long time I was able to keep it at bay using a carrier oil combined with oregano oil, I used this combination to kill the bacteria/fungi on my face that was part of the problem, but eventually the bacteria/fungi seemingly adapted and this was no longer effective. The sulphur/shea butter combination has been working for around 2years with no signs of diminished effectiveness.
I theorize that, in my case at least, there is some kind of autoimmune response going on. This is because the dermatitis would be worse if I consumed a trigger food such as milk. Likely my immune system was attacking the bacteria/fungi on my face whilst going after milk protein that had passed through my gut barrier into the blood stream.
I suffer from bacterial/fungal issues in other areas too but feel these are nearly resolved due to extensive work on my gut health, I say nearly as I have slipped at times and had the issues come back so the job cannot be finished.
To briefly address your mention of iodine in relation to facial flushing, I did 'the iodine protocol' for quite some time and it offered me no relief in that regard.
Perhaps your symptoms are too different to mine for my suggestion to be useful but I hope it helps you find some relief.
I have followed this thread for some years now and appreciate all of your relentless efforts in the face of such difficult struggles. Due to anxiety issues I find it difficult to talk in public forums but hope to be able to one day contribute something helpful from extensive self testing, as of now this is still a work in progress. I wish the best for all of you.
Thanks for the reply! I don't really have rosacea bumps or anything like that. I don't feel like mine is an exterior fungus problem. It's more like an interior inflammatory problem or something that gives me consistent flushing and blushing. I also have a very shiny face, but I use a good moisturizer and I'm not oily...
Looks like yet another guy suffering from AR5 inhibitor side effects is almost recovered now over on the Swole Source forum. I've been following the forum for a couple of years, and a number of guys have recovered following pretty much the same method which is;
- Cycling testosterone boosting herbs like tribulus, maca etc (cycling so you don't build up tolerance
- Clean diet and exercise
- Taking an aromatase inhibitor (I think this is key)
This guys recovered his finasteride side effects (all the usual - brain fog, sexual dysfunction, dry skin etc) using a low dose (0.5mg/day) of the aromatase inhibitorAnastrozole (Arimidex), and within weeks his brain fog had cleared and all sides were reduced. Over only something like 6 weeks he's also recovered from his sexual sides, got oily skin back, and went on to make complete recovery
QuoteI realised today that i feel bloody great, and last night my skin started getting oily again and has continued through today. Every symptom i had has now gone
[Edited link out]
His recovery is one of the quickest I've seen, and probably down to usingAnastrozole (Arimidex).
This guy has now pretty much fully recovered from Saw Palmetto sides (again its the usual AR5 inhibitor sides you get from finasteride, accutane, propecia, saw palmetto etc). He has used a DHT pro hormone (for body builders) which boosts DHT and is also a powerful aromatase inhibitor)
QuoteI'm coming to the finish of my second cycle of R-Andro Rx. I'm at a really good place right now to where I don't think about this near as much as I used to. In my previous posts months ago I mentioned being 70% or 80% recovered, but there's no way that was the case......compared to even those posts, I feel amazing today. I'm not back 100%, but I've made significant strides in the sexual ballpark lately and mentally I'm pretty much as I was before or damn close to it.
[Edited link out]
I'm pretty tempted to try a low dose ofAnastrozole (Arimidex), but it's just getting hold of it. I've tried many testosterone boosting herbs and have had decent benefits, but only up to a point. Tribulus resulted in an almost complete recovery mentally and sexually for me, but only for a couple of days, and I couldn't repeat it.
Pine pollen powder made me feel great for 4-5 weeks, much better sexual and mental sides, felt really confident and alpha-male like, but started to get high estrogen sides (very sensitive nipples etc), so stopped - clearly the testosterone was being aromatased into estrogen.
I've also tried Erase Plus (a natural aromatase inhibitor) and this also worked quite well, but no lasting benefit after stopping.
Anyone happen to have triedAnastrozole (Arimidex)?! I'm pretty impressed at just how quick this guy recovered on a low dose.
4 hours ago, Mike San said:Shouldn't you do a hormone test first to see if Estrogen is a problem for you? I wouldn't recommend taking a drug like Arimidex willy nilly, even if at low dosage.
If blood tests could identify the issues we're suffering from, we'd have been out of this mess long ago.
At best they give an indication of issues (testosterone is usually low-isa, but in range, mine is - free and total). I'm not necessarily saying to follow this method, I'm just pointing out that there are multiple recoveries following a similar protocols (raising testosterone, and taking an aromatase inhibitor to stop testosterone being converted into oestrogen)- the one using Arimidex is worth noting due to the very fast recovery time. The others have been more like months/years.
On 10/31/2016 at 5:55 AM, tanedout said:Looks like yet another guy suffering from AR5 inhibitor side effects is almost recovered now over on the Swole Source forum. I've been following the forum for a couple of years, and a number of guys have recovered following pretty much the same method which is;
- Cycling testosterone boosting herbs like tribulus, maca etc (cycling so you don't build up tolerance
- Clean diet and exercise
- Taking an aromatase inhibitor (I think this is key)
This guys recovered his finasteride side effects (all the usual - brain fog, sexual dysfunction, dry skin etc) using a low dose (0.5mg/day) of the aromatase inhibitorAnastrozole (Arimidex), and within weeks his brain fog had cleared and all sides were reduced. Over only something like 6 weeks he's also recovered from his sexual sides, got oily skin back, and went on to make complete recovery
[Edited link out]
His recovery is one of the quickest I've seen, and probably down to usingAnastrozole (Arimidex).This guy has now pretty much fully recovered from Saw Palmetto sides (again its the usual AR5 inhibitor sides you get from finasteride, accutane, propecia, saw palmetto etc). He has used a DHT pro hormone (for body builders) which boosts DHT and is also a powerful aromatase inhibitor)
[Edited link out]
I'm pretty tempted to try a low dose ofAnastrozole (Arimidex), but it's just getting hold of it. I've tried many testosterone boosting herbs and have had decent benefits, but only up to a point. Tribulus resulted in an almost complete recovery mentally and sexually for me, but only for a couple of days, and I couldn't repeat it.
Pine pollen powder made me feel great for 4-5 weeks, much better sexual and mental sides, felt really confident and alpha-male like, but started to get high estrogen sides (very sensitive nipples etc), so stopped - clearly the testosterone was being aromatased into estrogen.
I've also tried Erase Plus (a natural aromatase inhibitor) and this also worked quite well, but no lasting benefit after stopping.
Anyone happen to have triedAnastrozole (Arimidex)?! I'm pretty impressed at just how quick this guy recovered on a low dose.
everyone who can, should be tested for total estrogens (not just E2) and cortisol
Still one should always do hormone tests. That guy was on finasteride too, not tane. You can't really say the MOA of sides is the same , because, as you said, we don't know exactly what's wrong. That said, I still tested theory for myself by getting DHT tested...came back mid range.
Tane does something hormonal , its been proven in studies and could explain a lot of our sides. My T is low normal , but my cortisol is quite low. Regardless of causes, if one wants to 'optimize' hormone levels, taking Arimidex by itself, is unusual.
1 hour ago, Mike San said:Still one should always do hormone tests. That guy was on finasteride too, not tane. You can't really say the MOA of sides is the same , because, as you said, we don't know exactly what's wrong. That said, I still tested theory for myself by getting DHT tested...came back mid range.
Tane does something hormonal , its been proven in studies and could explain a lot of our sides. My T is low normal , but my cortisol is quite low. Regardless of causes, if one wants to 'optimize' hormone levels, taking Arimidex by itself, is unusual.
what cortisol tests did you get? and what were the numbers?
1 hour ago, tryingtohelp2014 said:2 hours ago, Mike San said:Still one should always do hormone tests. That guy was on finasteride too, not tane. You can't really say the MOA of sides is the same , because, as you said, we don't know exactly what's wrong. That said, I still tested theory for myself by getting DHT tested...came back mid range.
Tane does something hormonal , its been proven in studies and could explain a lot of our sides. My T is low normal , but my cortisol is quite low. Regardless of causes, if one wants to 'optimize' hormone levels, taking Arimidex by itself, is unusual.
what cortisol tests did you get? and what were the numbers?
Ive had over the years, saliva, blood , and 24 hr urine. I only have my bloods and urinary attached as the salivas were a long time ago.
On 10/26/2016 at 3:51 PM, MonsterDiesel said:Thanks for taking the time to reply. I've seen an instant improvement in concentration and motivation with inosine 500 mg once a day. It's supposed to improve your cognitive functions and motivation which it has for me. However, my memory still needs improvement. I'll stay on Lion's Mane for a few months and I'll report on improvements. I've used it before, years ago, and do remember it helped a little.
Tried Lion's mane for a few days. It gave me palpitations and now it goes in the bag with the others that didn't work for me. It did give me more energy though..
7 hours ago, tryingtohelp2014 said:everyone who can, should be tested for total estrogens (not just E2) and cortisol
Surely we've allnowconcluded that any test is a waste of time - the amount of blood tests this year that amounted to Nothing for me....what a waste of time!!
Its all just an experiment trying to get out of this mess - especially if there's irreversible damage involved!!??
14 minutes ago, JosephBuchignani said:> Surely we've allnowconcluded that any test is a waste of time
No. Fecal calprotectin test added years to my life, and hugely improved quality of life.
Im glad test helped you out. I've done more tests this year then ever before but have had no luck in pinpointing anything.
Even the colonoscopy and endoscopy concluding nothing.....nevermind. May the experiment continue I guess.....
You need to have your estrogen checked before you start trying to lower it.
Having low E can be as bad as having high E.
I have been on the swole source forum and believe that positive thinking, eating healthy, exercising and getting rid of stress will
all help. Everyone can only benefit from implementing all these things.
Testing is the next most single important thing you can do.
If your tests detect anything, hormone tweaking may be necessary using the most natural ways possible.
One thing I would say is get a copy of your tests and do your own research on them. I think doctors
are very dismissive and quick to right off below of above ranges, as not a problem.
I just started taking NSI-189. I'll be sure to post an update if I start to notice any positive results.
On 10/30/2016 at 4:55 PM, tanedout said:I'm pretty tempted to try a low dose ofAnastrozole (Arimidex), but it's just getting hold of it. I've tried many testosterone boosting herbs and have had decent benefits, but only up to a point. Tribulus resulted in an almost complete recovery mentally and sexually for me, but only for a couple of days, and I couldn't repeat it.
I thought I should mention again that I've also experienced such puzzling "micro-remissions" at times when taking those supposedly androgenic herbs like Maca and Tribulus. By this I mean the brain fog, feeling of mental drowsiness, and anhedonia disappear and I feel briefly like my old self with an actual personality (Obviously these are entirely subjective symptoms, and this will sound absolutely crazy to anyone who doesn't have to deal with this).
I've also noticed this effect has happened for me with three types of substances I've taken: the aforementioned herbal supplements, an OTC pregnenolone supplement, and (unexpectedly) prescription Doxycyline. I've noticed this usually only works one time, or at least very briefly, and then if I take a second dose anytime soon I don't receive any benefits, and if I keep taking it I "crash" and feel much worse for a while.
So I take it that guy's theory you mention is that the subsequent crashes are entirely caused by excess estrogen your body creates, and that taking a drug like Arimidex will entirely prevent this?
I doubt in my case that excess estrogen or a hormone imbalance is the only reason for the symptoms I've experienced, but I certainly wouldn't be surprised if it was one of the things Accutane screwed up, despite always having normal blood values.
Transferrin has been shown tointeractwithinsulin-like growth factor 2[15]andIGFBP3.[16]Transcriptional regulation of transferrin is upregulated by retinoic acid.[17]
https://en.wikipedia.org/wiki/Transferrin
I learn new things everyday.
Anyone has had constant high Iron levels since? I donate blood 3-4 times a year and yet, my iron levels are always high, especially Transferrin which is borderline high. Anything I'm missing?