Acne.org Products
11 minutes ago, SCOTT242 said:Hey I haven't been following the forum for a while but just wanted to report that weekly IV injections of glutathione is the only thing that has made me feel good in YEARS. It took 4-5 weeks to start feeling good. Was doing them weekly for maybe 10 weeks before we decided to stretch it out to every two weeks. I got busy and it turned into 3-4 weeks between IV's and I started feeling crappy again. So back to once a week for me, totally worth it. I am also now on Low Dose Naltrexone (LDN). I saw this mentioned in some earlier posts. It really makes my sleep terrible. I sleep ok but when I wake up I feel like I could sleep another 6 hours. I am on 2nd month. Started at 1.5mg, now at 3mg. In the beginning I had a stiff neck and headaches daily. The purpose of the glutathione and LDN for me is to increase my regulatory T-cells. This will help keep my immune system from attacking myself which is my primary (only?) issue at this point post tane.
Injections of Glutathione- is that something you discuss with Doctor?? Haven't heard of that method before. Pls explain what you gain from it i.e less tired, more hydrated? I know it helps immune system buthow would you sum up the feeling from taking it?
Does the LDN help with energy??
Thx for your post!!
21 hours ago, cnb30 said:What is LDN?
also, has anyone here tried death yet? That seems like the best option. After all, it's not like we're already partially murdered or anything.
also, does anyone here know of any drugs that REALLY alter your brain so atleast I can be somewhere else?
Well if you're serious you can look into NSI-189 I've been taking it for 2 weeks now, working well.
58 minutes ago, ehohel said:22 hours ago, cnb30 said:What is LDN?
also, has anyone here tried death yet? That seems like the best option. After all, it's not like we're already partially murdered or anything.
also, does anyone here know of any drugs that REALLY alter your brain so atleast I can be somewhere else?
Well if you're serious you can look into NSI-189 I've been taking it for 2 weeks now, working well.
Interesting; Would you mind elaborating? What effects have you noticed?
1 hour ago, john86 said:Interesting; Would you mind elaborating? What effects have you noticed?
It's basically an anti-depressant that's not done with trials yet, but the trails look very very successful right now. It won't remove accutane from your body or anything like that, but as for depression I'm having great results 2 weeks in, while the trials show it starts working usually almost a month in. It literally grows your hippocampus section of your brain, so the effects remain when you're not taking the drug. Obviously, venture at your own risk, since it's not completed its medical trials. But we know the side effects it gives usually go away after you stop taking it, unlike SSRI's.
On 10/18/2016 at 12:43 AM, john86 said:Interesting; Would you mind elaborating? What effects have you noticed?
Sorry, I have to hijack this. I took NSI-189 for five months this past year. It helped with some of my cognitive issues. It made it so I had the attention span to read again, and certainly helped with emotional depth as well. My vision improved, which is a textbook sign of antidepressant effects. There were many days where I felt much bigger capacity for pleasure and excitement. Results were not always consistent, but I think it left me sharper, less depressed in the end. To this day, I feel deeper when the emotions are there. I was able to partially recapture the feeling of getting lost in a preferred activity again (granted, not at pre-Accutane levels). I do plan to return to this substance again.
So one side effect was increased anxiety, which made sense since it enhances every emotion. I welcomed this, as an anhedonic. I also experienced nerve pain, which is really what inspired me take a break. This drug's effects are not acute. They are cumulative. You cannot get high off of it.
That being said, there are lower risk substances that cause neurogensis, some of which I take regularly. Examples: Tianeptine (on it), Lion's Mane (on it), Curcumin, Semax. Dare I mention SSRIs?! Yep, they cause neurogensis too. Don't get hung up on this forbidden fruit. 
But I will say that NSI-189 is one of the few substances capable of touching my anhedonia.
On 10/18/2016 at 2:26 AM, ehohel said:IIt literally grows your hippocampus section of your brain, so the effects remain when you're not taking the drug. Obviously, venture at your own risk, since it's not completed its medical trials.
The rat studies were excellent, as healthy rats saw a 20% increase in hippocampal size. In humans, the effect does not appear as significant, but it does seem to help depression nonetheless. [Edited link out] are the posted results from Phase 1b clinical trials. " The post hoc repeated measures analysis of variance suggested a modest but not statistically significant increase in the left hippocampal volume in the NSI-189-treated patients ." And: " In the control site, the trend was non-significant on the left side (b=ˆ’0.03, P=0.74), and significant on the right side (b=0.32, P=0.049). Peculiar. So a part of brain that wasn't even intended to be targeted by the drug (amygdala in this case) saw more growth than the hippocampus! All in all, I'm not sure what to make of it. Perhaps this finding explains the anxiety more than it discredits the ability for NSI to cause neurogenesis in the hippocampus! lol.
Post accutane, are our problems more to do with hippocampus or pituitary??
There are pituitary supplements that I'm yet to try, plus I haven't tried oxygen therapy just yet. For me I'll explore other avenues before jumping on a drug that's still being trailed. Also, at some point you'll have to come off that drug - what's the plan after that??
Can I moisturize with sunflower oil? Or would that be bad because of the vitamin A in it? Does it even matter if I put a drop or two of oil on my face if it has vitamin A in it? Could it bring more symptoms back? Make blushing and flushing worse? I was hoping it could help thicken my skin barrier... I've heard it can do that.
7 hours ago, TrueJustice said:Post accutane, are our problems more to do with hippocampus or pituitary??
There are pituitary supplements that I'm yet to try, plus I haven't tried oxygen therapy just yet. For me I'll explore other avenues before jumping on a drug that's still being trailed. Also, at some point you'll have to come off that drug - what's the plan after that??
People report the effects stay after getting off NSI, it seems like a permanenttreatment. In fact most feel better after getting off cause the anxiety goes away, but everything good stays. Of course we don't know the long term effects right now. So I obviously cannot endorse taking it, I was simply announcing my current success with it.
[Edited link out]
I've been trying another approach to my issues through a forum that doesn't deal specifically with post-Accutane issues. Many things were recommended to me that I definitely suggest you guys look over.
I've tried Iodine supplementation for the first time last night and had crazy vivid dreams, which prompted me to research a bit, and I found this. Funny. First link I click, solely regarding Iodine and Dreams, and the first reply speaks of Finasteride. I haven't gone through the 400+ pages here. How has Iodine affected you long term? I feel very different this morning.
[removed]
4 hours ago, ehohel said:People report the effects stay after getting off NSI, it seems like a permanenttreatment. In fact most feel better after getting off cause the anxiety goes away, but everything good stays. Of course we don't know the long term effects right now. So I obviously cannot endorse taking it, I was simply announcing my current success with it.
This is encouraging and I appreciate you posting about it. I know some people have researched brain changes after tane which is why I asked if hippocampus or pituitary is more affected - be good to do a brain scan of someone after tane, then again after taking NSI, see if there's any positive changes???
I'm still on the search for something that hydrates the body? I have no doubt that tane dried up everything including our brains!!
Baxyl is the only thing be offered up at this point.
Still, its good to know there is something that can take away anxiety, I could sure use something to help with that at the moment. Thx for info on NSI
On 10/19/2016 at 7:34 AM, ACCUiTy_drANE said:That being said, there are lower risk substances that cause neurogensis, some of which I take regularly. Examples: Tianeptine (on it), Lion's Mane (on it), Curcumin, Semax. Dare I mention SSRIs?! Yep, they cause neurogensis too. Don't get hung up on this forbidden fruit.
Have you tried Noopept? One of the guys who recovered his sexual side using RSO earlier on this thread found he could function normally mentally when taking noopept and astaxanthin. I've tried the latter, but didn't notice much on it's own.
For mental clarity methyl B12 and l-carnitine fumarate definitely help me without a doubt. l-carnitine fumarate probably has more effect than the B12.
3 hours ago, tanedout said:Have you tried Noopept?
Yes, I've tried intranasal Noopept a few times, but I never felt much. The fact some people report short-term memory loss on it has scared me away from using it more. Then again, one of my friends loved its effects on vision and mood. Since we're on the topic of Russian peptides sold by nootropic vendors, I will say I had moderately good effects from Selank. It helped promote a feeling of awakeness and slight increased feeling of well-being, but nothing to go crazy over.
I am planning to fill a prescription for low-dose Naltrexone in the coming weeks. Seeing as LDN upregulates the body's production of endorphins, I will be curious to combine it with Selank or Semax at some point. Both of these peptides are enkephalinase inhibitors, meaning they halt the break down of your body's natural opioids. So the combination of LDN and Selank/Semax could be synergistic (or disrupt LDN's action entirely, haha). In any case, all of the peptides we have talked about appear to helpful for some people. The science backs it up. I think it's important to try and stick to one thing for a while before quitting, especially when dealing with these areas health science (i.e., neurogenesis and immune correction).
3 hours ago, tanedout said:For mental clarity methyl B12 andl-carnitine fumarate definitely help me without a doubt.l-carnitine fumarate probably has more effect than the B12.
I've tried l-Carnitine and Acetyl-l-Carnitine. The latter provides focus, but I still feel physical fog. In fact, I've felt effects from many supplements, but it often (not always) feels like "background noise" to the greater problem of my mental haze. Fingers crossed for LDN.
My disc degeneration and joint pain/arthritis is killing me. Is there a way to fix or correct this at all? Like I'm not saying the damage that has been done can be corrected, but I just want to find a way to halt it. I know its my own immune system doing it. I also know I can't be the only one here having these problems.
I would really appreciate it someone could shed some light whether its from dealing with these symptoms to suggestions about dealing with them. I feel for everyone who has been affected by this horrible drug. I feel like I've been robbed of my teens and early adulthood.
Welcome to the club. Been dealing with with countless 'itis' diseases ever since cessation of accutane. Some come and go, but the main ones that stay are arthritis, tendonitis, gingivitis, tinnitius, pancreatitis (3 years in), and currently a random occurence of Blepharitis (inflammation of the eyelid). Fun stuff. It's clearly systemic. And our Immune system (or what's left of it).
Hello all!
I'm really struggling with this facial redness and blushing thing. It is way bad. Anyone have any ideas/thoughts/experiences? Please...
BTW, I had pretty bad digestive problems from accutane and drinking a little bentonite clay helped, but drinking real kefir everyday has completely healed my digestive system. All of you with digestive troubles, look it up! It's way good for you.
Hi guys, I recently came off Accutane about 4 months ago.
My symptoms are:
- decreased sex drive
- erectile dysfunction
- feeling dehydrated (e.g. dry mouth, etc) even after drinking lots of water
- needing to urinate a lot (a definite cause from accutane and has sometimes been very bad)
- I get headaches easily
I had some tests done and was found to have low testosterone. I plan to go to a different doctor (perhaps a hormone specialist) and get a full sex hormone test done so I can see my estrogen levels.
I have read some of this thread but missed a lot. I believe that the only thing everyone seems to be recommending so far is Calcium DGlucarate. Can anyone confirm that taking this has helped any similar symptoms to mine??
And are there any other supplements or treatments, etc that have worked on similar symptoms?
Thanks
49 minutes ago, UnevenPetal said:Hi guys, I recently came off Accutane about 4 months ago.
My symptoms are:
- decreased sex drive
- erectile dysfunction
- feeling dehydrated (e.g. dry mouth, etc) even after drinking lots of water
- needing to urinate a lot (a definite cause from accutane and has sometimes been very bad)
- I get headaches easily
I had some tests done and was found to have low testosterone. I plan to go to a different doctor (perhaps a hormone specialist) and get a full sex hormone test done so I can see my estrogen levels.
I have read some of this thread but missed a lot. I believe that the only thing everyone seems to be recommending so far is Calcium DGlucarate. Can anyone confirm that taking this has helped any similar symptoms to mine??
And are there any other supplements or treatments, etc that have worked on similar symptoms?Thanks
All those symptoms will absolutely 100% be down to Accutane. If I were you I'd be eating a really clean diet with plenty of (ideally organic) vegetables, meats and completely avoid processed foods and fizzy drinks etc, maybe go paleo if you can. Some people have had symptoms for some months after stopping the drug, then recovered.
On 19 octobre 2016 at 6:05 PM, Kynarr said:'ve tried Iodine supplementation for the first time last night and had crazy vivid dreams, which prompted me to research a bit, and I found this. Funny. First link I click, solely regarding Iodine and Dreams, and the first reply speaks of Finasteride. I haven't gone through the 400+ pages here. How has Iodine affected you long term? I feel very different this morning.
Hi, what is your iodine supplement? Iodoral is so expensive. One or two weeks ago I have had a few nights with very vivid dreams, they were closer to nightmares but I think I was feeling better/different the day after. Maybe I was getting some more iodine from my food..
Helpmeoutbuddies11- You can read through and check out this thread that a couple years ago some Accutane suffers made in the Rosacea forum. Do youhave flushing and blushing consistently or just at random times?
http://www.acne.org/messageboard/topic/193804-post-accutaneminocycline-facial-flushing/
22 hours ago, Dheid1 said:I was only on accutane for 1 month & stopped taking it.. I have experienced a lot of bad symptoms.. With only being on it 1 month should my body recover or am I a lost cause?
The dosage is almost certainly irrelevant - some people have got persistent sides from taking a single pill - the same as with finasteride, saw palmto etc. I only took 10mg/day for 30 days but still have persistent sides 6+ years later.
If you only stopped one month ago just make sure you're eating a really clean diet, no alcohol etc and give your body its best shot at recovering.