On 9/17/2016 at 11:47 AM, helpmeoutbuddies11 said:

Has anyone had significant success with cannabis oil? Is it just hemp oil? A specific kind of oil? How do you take it? Where do you buy it?

[removed]

You are looking for Rick Simpson Oil.
try getting your hands on that, very expensive but it has some major healing effects.

On 16/9/2016 at 0:37 AM, tryingtohelp2014 said:

check your estrogen?

A lot of libido ED symptoms match up with "Estrogen Dominance" google it

you can have a normal testosterone reading.. yes be very high in other free hormones. This calcium D glucarate helps with that as well.

thank you, dosage and time for calcium d glucarate?

I read that CBD oil produces the same benefits, has no high and is legal. It has different THC levels but provides all the same benefits. It's almost exactly the same and its potency is the same. It is also much cheaper. Do we simply take it orally? Has anyone had success with this?

[removed]

On 9/17/2016 at 9:47 AM, MovingOnMusicGal said:

I just want to share that I've been taking LDN for 2 years and it hasn't cured anything for me. It just helps with some nighttime inflammation and mood some.

Cannabis oil on the other hand, well that's starting to look promising. Will keep you guys updated.

Since accutane I have had fairly bad problems with redness and flushing. Could LDN potentially help flushing?

CBD oil has benefits and you don't get high off it bonus.

Vitamin A turnover in the liver is increased when the liver stores of vitamin A are ample.
When the vitamin A in the liver is low, turnover is decreased.

In other words, we should ingest more vitamin A to hopefully turnover the accutane from the liver (if it's stored there, which it most likely is).
I recommend eating pasture-raised liver (MUST be organic).
[Edited link out]

On 9/17/2016 at 1:47 AM, helpmeoutbuddies11 said:

Has anyone had significant success with cannabis oil? Is it just hemp oil? A specific kind of oil? How do you take it? Where do you buy it?

I used it for approximately one month and did not notice anything. Specifically, I use Cannabidiol at 20 mg per day. I didn't notice a thing, although maybe slight relaxation at 50 mg. Cannabidiol is a (researched) compound found in the marijuana plant. It is the non-psychoactive component, contrary to THC. It has been found to have all sorts of cognitive, anti-inflammatory, and anti-cancer benefits. Hemp oil is simply made from hemp seeds. It contains little to no Cannabidiol. To make matters confusing, sometimes Cannabidiol is legally sold as hemp in order to make marketing easier. This practice is permissible under U.S. law as long as the THC content is below .3%. In that case, the compound Cannabidiol is completely legal in most areas of the world, in fact. So if you decide to buy Cannabidiol, you should ask the vendor to provide proof that their product actually contains substantial amounts of this compound. The difference between hemp oil and Cannabidiol is in the chemistry, not the name. You probably won't find genuine Cannabidiol at your local grocery store or Amazon. I Googled around and found a grower in Colorado who breeds his plants to be naturally low in THC (below .3%), and extremely high in Cannabidiol. I was essentially taking medical Cannabidiol (orally), but again, I noticed nothing. If you want more details on acquiring this legal product, PM me.

On 9/16/2016 at 11:47 PM, helpmeoutbuddies11 said:

Has anyone had significant success with cannabis oil? Is it just hemp oil? A specific kind of oil? How do you take it? Where do you buy it?

My son has had success with RSO. After several months of 0 erections ever. Earlier in this forum and also on the "allthingsmale" forum, post accutane sufferers gave instructions on how to use it. My son was never able to get up to the amount that they said worked for them, but even taking it sporadically and in much smaller doses, he restored himself to several mornings a week back to the normal morning erections. PM me and I can give you specifics about how to get it if you'd like. I earlier speculated that maybe CBD alone would work, but I'm not so sure anymore.

cnb30 - if you're still around, and I hope you are! My son also suffered from the emotional deadness that accutane can cause. His zest for living and interest in previous things came back after a few weeks on RSO. Get somewhere where you can get it. Don't take an anti-depressant - there's too much risk involved and they can cause the same sexual sides accutane does.

10 hours ago, Justmom said:

My son has had success with RSO. After several months of 0 erections ever. Earlier in this forum and also on the "allthingsmale" forum, post accutane sufferers gave instructions on how to use it. My son was never able to get up to the amount that they said worked for them, but even taking it sporadically and in much smaller doses, he restored himself to several mornings a week back to the normal morning erections. PM me and I can give you specifics about how to get it if you'd like. I earlier speculated that maybe CBD alone would work, but I'm not so sure anymore.

cnb30 - if you're still around, and I hope you are! My son also suffered from the emotional deadness that accutane can cause. His zest for living and interest in previous things came back after a few weeks on RSO. Get somewhere where you can get it. Don't take an anti-depressant - there's too much risk involved and they can cause the same sexual sides accutane does.

What was your sons dosage , it's important because it gives me an idea on dosage vs long term damage .

Has anyone figured out how to overcome the cellular dehydration issue?

I actually feel better when I restrict fluid intake, because when I do drink water, it just comes out through my skin, eyes, bowels etc. Causing inflammation in these places.

It doesn't seem like water can penetrate my cells anymore.

On 17 September 2016 at 6:47 AM, helpmeoutbuddies11 said:

Has anyone had significant success with cannabis oil? Is it just hemp oil? A specific kind of oil? How do you take it? Where do you buy it?

There are some people who've recovered using RSO, but also a number who've tried and seen no benefits (including myself). Other than being very hard to obtain, I really had trouble functioning at work the day after taking it before bed, and there is no way I could get anywhere near the recommended dose - I was absolutely fcuked on much smaller amounts. Probably only managed to consume 5-10g over 6 months. The one benefit I got was improved orgasm, that was only when it was in my system though, presumably due to increased dopamine.

Also took loads of CBD oils, including RSHO at 1g per day for a month, and smaller amounts for longer. Got absolutely nothing from that stuff, so wouldn't recommend wasting loads of money on it.

Currently I've been following methylation protocols for the past couple of months. There is absolutely no doubt that accutane messes up biological processes involved with methylation, and just look at all the studies showing post 'treatment' you have low folate, excessive homocysteine etc.

This thread details some of the protocols, and is well worth following. I've tried to follow 'Freddds' protocol, but really struggle with ADB12 (one of the active forms of vitamin B12 that doesn't require enzymatic conversation to be used) - this stuff makes me extremely fatigued.

Have got some improvements with 2mg MB12 (the other active form of B12) and 1 x L-Carnitine Fumarate - much better mental clarity. I'm going to introduce methylfolate at some point as clearly that's pretty key.

Everyone should read this thread

http://howirecovered.com/active-b12-therapy-faq/

Rich Van K over on the CFS forum phoenix rising may well have been along the right lines with his theory of tane sides, but I can't find that anyone has actually tried his suggest of a high does of mehtylafolate (would probably require taking deplin (15mg) and a few mg of MB12.

This is his hypothesis;

You mentioned Roaccutane. I've probably heard from four PWMEs now who had this in their history. In the U.S., it's just called Accutane. I don't know if this is relevant to your case, but it is known that one of the effects of Roaccutane (also called isotretinoin or 13cis-retinoic acid) is to raise the expression of the gene that codes for glycine N-methyltransferase. This enzyme is the "safety valve" that normally prevents the SAMe to SAH ratio from going too high, and it works by taking methyl groups from SAMe and putting them on glycine to form sarcosine. The sarcosine then gives the methyl groups to tetrahydrofolate to form 5,10 methylene tetrahydrofolate, which can then be used to make thymidine for DNA production, or can be used to make methylfolate to drive the methionine synthase reaction.

When Roaccutane raises the activity of glycine N-methyl transferase, the result is that the ratio of SAMe to SAH goes too low, and the person's methylation capacity drops. This affects a large number of reactions in the cells that require methyl groups, and in particular, it affects the methylation of DNA. Methylation in general silences the expression of genes, so if the methylation capacity drops, I think we should expect higher gene expression to occur, which could cause many changes in the biochemistry as more copies of various enzymes and other proteins would be made.

In most people, when treatment with Roaccutane is stopped, the methylation apparently returns to normal. However, I suspect that in some cases, the methylation gets "stuck" in a positive feedback loop, i.e. a vicious circle mechanism, so that the expression of the glycine N-methyl transferase stays high, and the lowered methylation capacity prevents methylation and silencing of the gene expression for this enzyme.

Since methylfolate has the additional property that it downregulates glycine N-methyl transferase at the biochemical level, treatment with high dose methylfolate may be able to break this vicious circle. So far, this is just a hypothesis.

You mentioned that you have responded well to supplementing SAMe. I think that suggests that you do have a methylation deficit, and perhaps it started with the Roaccutane treatment. However, I understand that you did not respond well to methylfolate treatment or B12 treatment or the combination, and I don't know what to make of that. It could be that they actually were working to restore your methylation function, and that can cause symptoms. The cold sores suggest that your immune system was becoming more active, and this is an expected effect of restoring methylation, folates and glutathione. Perhaps it would help to start with lower dosages of B12 and methylfolate.

If it is feasible for you to do some lab testing, the combination of a Health Diagnostics methylation pathways panel and a 40 plasma amino acids test or a urine amino acids test would help to determine what's going on with your methylation cycle, folate metabolism, glutathione level and the amino acids associated with all of the above.

The fact that you benefited from zinc and B6 suggests that you might have HPU (also called KPU), though you might just have been low in these essential nutrients. Again, if testing is feasible, you might consider the Metametrix ION profile, which I believe is available in Australia, and which will give information about other possible deficiencies. There is a fatty acids panel included in this profile as well, and that may help in sorting out your response to fish oils and evening primrose oil. It will also give information about potassium and magnesium. As you may know, the cells tend to be low in both in ME/CFS. Both glutathione and B6 seem to be involved in maintaining the intracellular magnesium levels, and the potassium level requires ATP, which is low in ME/CFS because of the mito dysfunction.

Manganese is also on the ION profile.

Sounds as though you have fructose malabsorption. MSG is a big source of glutamate, and the fact that you are sensitive to it could mean low B6 (or B2) or a state of excitotoxicity because of glutathione depletion. The testing I mentioned would help to sort this out. I don't know if your other food sensitivities are allergies (type 1 sensitivity, involving IgE and histamine) or IgG food sensitivities due to a leaky gut. Do you have symptoms associated with the gut?

I don't know what is causing the muscle tension. It could be mito dysfunction, causing low ATP production. ATP is actually used to release contraction of the muscle fibers, and to "cock" them for the next contraction. This could also explain the problems with strength and endurance. If the above testing is done, it would be possible to see what is going on with the mitochondria.

The collapsed vertebra in your neck could also be affecting the nervous system and causing some of the symptoms you described.

I guess that's about all I have to offer, based on the available information. If it is feasible to run the tests I mentioned, I think you could know a lot more about your condition and some clues as to how to deal with it better.

Best regards,

Rich

http://forums.phoenixrising.me/index.php?threads/progress-is-getting-there-rich-can-you-pitch-in-on-this.16078/

One of the sides of tane is also significantly raised homocysteine, and this along could account for many side effects. To lower this you can take active B12 (MB12), methylfolate and TMG

Case study:lowering homocysteine 'saved my life' Chris K felt very unwell, with constant tiredness, worsening memory and concentration and little zest for life. He was depressed, had no sex drive and felt brain dead. His homocysteine score was 119. He changed his diet and took homocysteine-lowering nutrients and, within three months, his homocysteine level dropped to 19. After 6 months it had dropped to 11. He cannot believe how well he now feels. His memory and concentration are completely restored. He has boundless energy from 6am until 10pm He now exercises for an hour every day and has lost weight. "You have saved my life, or at least made it worth living again. Iam a new man and my love life has perked up," says Chris, who followed the supplement and dietary guidelines inThe H Factor. Nutrients and levels to supplement, depending on your homocysteine score

https://www.patrickholford.com/advice/how-to-lower-your-homocysteine-level

Methylation has been discussed many times on here, but never with the right supplements (I've tried before , and looking back was wasting my time). A significant number of people on the CFS board have had decent improvements, so its worth trying.

It sounds like you need to be careful supplementing with "methylfolate". How many have tried it and had a positive result?

Interesting that all the side effects one may experience with taking methylfolate are exactly what we all experience post accutane...what's that all about??

Didnt notice anything from taking TMG supplement but maybe I didn't give it long enough!? Or maybe I forgot to take it with Cannibas oil.....as usual it's all just a stab in the dark trying to get any relief with anything, such a joy isn't it......

20 hours ago, tanedout said:

There are some people who've recovered using RSO, but also a number who've tried and seen no benefits (including myself). Other than being very hard to obtain, I really had trouble functioning at work the day after taking it before bed, and there is no way I could get anywhere near the recommended dose - I was absolutely fcuked on much smaller amounts. Probably only managed to consume 5-10g over 6 months. The one benefit I got was improved orgasm, that was only when it was in my system though, presumably due to increased dopamine.

Also took loads of CBD oils, including RSHO at 1g per day for a month, and smaller amounts for longer. Got absolutely nothing from that stuff, so wouldn't recommend wasting loads of money on it.

Currently I've been following methylation protocols for the past couple of months. There is absolutely no doubt that accutane messes up biological processes involved with methylation, and just look at all the studies showing post 'treatment' you have low folate, excessive homocysteine etc.

This thread details some of the protocols, and is well worth following. I've tried to follow 'Freddds' protocol, but really struggle with ADB12 (one of the active forms of vitamin B12 that doesn't require enzymatic conversation to be used) - this stuff makes me extremely fatigued.

Have got some improvements with 2mg MB12 (the other active form of B12) and 1 x L-Carnitine Fumarate - much better mental clarity. I'm going to introduce methylfolate at some point as clearly that's pretty key.

Everyone should read this thread

http://howirecovered.com/active-b12-therapy-faq/

Rich Van K over on the CFS forum phoenix rising may well have been along the right lines with his theory of tane sides, but I can't find that anyone has actually tried his suggest of a high does of mehtylafolate (would probably require taking deplin (15mg) and a few mg of MB12.

This is his hypothesis;

You mentioned Roaccutane. I've probably heard from four PWMEs now who had this in their history. In the U.S., it's just called Accutane. I don't know if this is relevant to your case, but it is known that one of the effects of Roaccutane (also called isotretinoin or 13cis-retinoic acid) is to raise the expression of the gene that codes for glycine N-methyltransferase. This enzyme is the "safety valve" that normally prevents the SAMe to SAH ratio from going too high, and it works by taking methyl groups from SAMe and putting them on glycine to form sarcosine. The sarcosine then gives the methyl groups to tetrahydrofolate to form 5,10 methylene tetrahydrofolate, which can then be used to make thymidine for DNA production, or can be used to make methylfolate to drive the methionine synthase reaction.

When Roaccutane raises the activity of glycine N-methyl transferase, the result is that the ratio of SAMe to SAH goes too low, and the person's methylation capacity drops. This affects a large number of reactions in the cells that require methyl groups, and in particular, it affects the methylation of DNA. Methylation in general silences the expression of genes, so if the methylation capacity drops, I think we should expect higher gene expression to occur, which could cause many changes in the biochemistry as more copies of various enzymes and other proteins would be made.

In most people, when treatment with Roaccutane is stopped, the methylation apparently returns to normal. However, I suspect that in some cases, the methylation gets "stuck" in a positive feedback loop, i.e. a vicious circle mechanism, so that the expression of the glycine N-methyl transferase stays high, and the lowered methylation capacity prevents methylation and silencing of the gene expression for this enzyme.

Since methylfolate has the additional property that it downregulates glycine N-methyl transferase at the biochemical level, treatment with high dose methylfolate may be able to break this vicious circle. So far, this is just a hypothesis.

You mentioned that you have responded well to supplementing SAMe. I think that suggests that you do have a methylation deficit, and perhaps it started with the Roaccutane treatment. However, I understand that you did not respond well to methylfolate treatment or B12 treatment or the combination, and I don't know what to make of that. It could be that they actually were working to restore your methylation function, and that can cause symptoms. The cold sores suggest that your immune system was becoming more active, and this is an expected effect of restoring methylation, folates and glutathione. Perhaps it would help to start with lower dosages of B12 and methylfolate.

If it is feasible for you to do some lab testing, the combination of a Health Diagnostics methylation pathways panel and a 40 plasma amino acids test or a urine amino acids test would help to determine what's going on with your methylation cycle, folate metabolism, glutathione level and the amino acids associated with all of the above.

The fact that you benefited from zinc and B6 suggests that you might have HPU (also called KPU), though you might just have been low in these essential nutrients. Again, if testing is feasible, you might consider the Metametrix ION profile, which I believe is available in Australia, and which will give information about other possible deficiencies. There is a fatty acids panel included in this profile as well, and that may help in sorting out your response to fish oils and evening primrose oil. It will also give information about potassium and magnesium. As you may know, the cells tend to be low in both in ME/CFS. Both glutathione and B6 seem to be involved in maintaining the intracellular magnesium levels, and the potassium level requires ATP, which is low in ME/CFS because of the mito dysfunction.

Manganese is also on the ION profile.

Sounds as though you have fructose malabsorption. MSG is a big source of glutamate, and the fact that you are sensitive to it could mean low B6 (or B2) or a state of excitotoxicity because of glutathione depletion. The testing I mentioned would help to sort this out. I don't know if your other food sensitivities are allergies (type 1 sensitivity, involving IgE and histamine) or IgG food sensitivities due to a leaky gut. Do you have symptoms associated with the gut?

I don't know what is causing the muscle tension. It could be mito dysfunction, causing low ATP production. ATP is actually used to release contraction of the muscle fibers, and to "cock" them for the next contraction. This could also explain the problems with strength and endurance. If the above testing is done, it would be possible to see what is going on with the mitochondria.

The collapsed vertebra in your neck could also be affecting the nervous system and causing some of the symptoms you described.

I guess that's about all I have to offer, based on the available information. If it is feasible to run the tests I mentioned, I think you could know a lot more about your condition and some clues as to how to deal with it better.

Best regards,

Rich

http://forums.phoenixrising.me/index.php?threads/progress-is-getting-there-rich-can-you-pitch-in-on-this.16078/

One of the sides of tane is also significantly raised homocysteine, and this along could account for many side effects. To lower this you can take active B12 (MB12), methylfolate and TMG

Case study:lowering homocysteine 'saved my life' Chris K felt very unwell, with constant tiredness, worsening memory and concentration and little zest for life. He was depressed, had no sex drive and felt brain dead. His homocysteine score was 119. He changed his diet and took homocysteine-lowering nutrients and, within three months, his homocysteine level dropped to 19. After 6 months it had dropped to 11. He cannot believe how well he now feels. His memory and concentration are completely restored. He has boundless energy from 6am until 10pm He now exercises for an hour every day and has lost weight. "You have saved my life, or at least made it worth living again. Iam a new man and my love life has perked up," says Chris, who followed the supplement and dietary guidelines inThe H Factor. Nutrients and levels to supplement, depending on your homocysteine score

https://www.patrickholford.com/advice/how-to-lower-your-homocysteine-level

Methylation has been discussed many times on here, but never with the right supplements (I've tried before , and looking back was wasting my time). A significant number of people on the CFS board have had decent improvements, so its worth trying.

Nice post. I researched B12 deficiency and homocyteine in some detail but figured B12 level was good 450 so assumed H would be ok.
Do you think homocysteine needs testing independently of B12?

On 9/19/2016 at 9:14 AM, Gladiatoro said:

What was your sons dosage , it's important because it gives me an idea on dosage vs long term damage .

He took 40 mg 2x/day for, I think, 6 months. Total 14,400 mg.

The only side effect he complained about was sexual dysfunction. But blood tests show his billirubins high, and I know he still suffers from dryness, especially his lips.

3 hours ago, hatetane said:

Nice post. I researched B12 deficiency and homocyteine in some detail but figured B12 level was good 450 so assumed H would be ok.
Do you think homocysteine needs testing independently of B12?

I would say it's definitely worth getting homocysteine checked yeah, and if you do please post the result up. I'm planning on getting this done myself at some point, and would be surprised if it's not high. As I carry the MTHFR gene defect though (confirmed through 23andme), I'm recommended to take basically the same sups for that anyway.

There are loads of tests showing elevated homocysteine after accutane/isotreitinoin 'treatment';

Hcy levels are elevated in patients on Iso treatment for CA. It may be due to either the inhibition of cystathionine-beta-synthase, an enzyme required in the metabolism of Hcy, by the drug and/or the liver dysfunction. Daily supplementation with vitamin B12 and folate, which are the cofactors of the enzymatic reactions involved in Hcy metabolism, can lower plasma levels of Hcy

http://www.ncbi.nlm.nih.gov/pubmed/18608712

The benefit of methylcobalamin administration on lowering plasma tHcy levels in HD patients was remarkable. Our study suggested that both supplementations of high-dose folic acid and methylcobalamin are required for the remethylation pathway to regain its normal activity.

http://www.ncbi.nlm.nih.gov/pubmed/11981084

This has been mentioned before on this thread, and also I've seen it mentioned on other forums too, but there seems to be a real lack of understanding between the active forms of the vitamin, and other forms which only became active after an enzymatic reaction in the body (and this ability is almost certainly impaired). There is also the issue that methylfolate is fairly expensive to supplement in high doses.

On 9/21/2016 at 6:08 AM, tanedout said:

I would say it's definitely worth getting homocysteine checked yeah, and if you do please post the result up. I'm planning on getting this done myself at some point, and would be surprised if it's not high. As I carry the MTHFR gene defect though (confirmed through 23andme), I'm recommended to take basically the same sups for that anyway.

There are loads of tests showing elevated homocysteine after accutane/isotreitinoin 'treatment';

Hcy levels are elevated in patients on Iso treatment for CA. It may be due to either the inhibition of cystathionine-beta-synthase, an enzyme required in the metabolism of Hcy, by the drug and/or the liver dysfunction. Daily supplementation with vitamin B12 and folate, which are the cofactors of the enzymatic reactions involved in Hcy metabolism, can lower plasma levels of Hcy

http://www.ncbi.nlm.nih.gov/pubmed/18608712

The benefit of methylcobalamin administration on lowering plasma tHcy levels in HD patients was remarkable. Our study suggested that both supplementations of high-dose folic acid and methylcobalamin are required for the remethylation pathway to regain its normal activity.

http://www.ncbi.nlm.nih.gov/pubmed/11981084

This has been mentioned before on this thread, and also I've seen it mentioned on other forums too, but there seems to be a real lack of understanding between the active forms of the vitamin, and other forms which only became active after an enzymatic reaction in the body (and this ability is almost certainly impaired). There is also the issue that methylfolate is fairly expensive to supplement in high doses.

Thanks.

[Edited link out]

Just out of interest - how many of you have reported you side effects.

I must admit it baffles me that there are some people on this forum who haven't even had a blood test.

It is so important to get as much testing done as possible.
If possible get a diagnosis then report your sides.

Just looked at this website.Interesting to see other reported side effects that i wasn't aware of before.

Hello people,

I've been lurking in this topic for quite some time. However I've not seen anyone with my specific symptoms.
Long story short, I'm 20 years old, male and I took accutane for 9 months 20mg/day (very low I know). It worked wonders, acne dissapeared.
However I started to develop horrible dry eyes/mouth/skin in the last month. My skin thankfully healed after a year, however my dry eyes and mouth did not. Many fruitless visits to eye doctors later, my eyes are by far the worst issue now. I have 0 tear production, almost no oils and red veiny eyes. Other than that, I'm prefectly healthy.I've noticed symptoms tend to worsen when I eat a lot of fat. It's like the accutane reactivates the days after.

Does anyone recognize this? I'm getting desperate for some relief. Eye drops don't do much. I use them during the day/night to prevent any further damage to my eyes.

On 9/23/2016 at 12:26 AM, tyrantix said:

Hello people,

I've been lurking in this topic for quite some time. However I've not seen anyone with my specific symptoms.
Long story short, I'm 20 years old, male and I took accutane for 9 months 20mg/day (very low I know). It worked wonders, acne dissapeared.
However I started to develop horrible dry eyes/mouth/skin in the last month. My skin thankfully healed after a year, however my dry eyes and mouth did not. Many fruitless visits to eye doctors later, my eyes are by far the worst issue now. I have 0 tear production, almost no oils and red veiny eyes. Other than that, I'm prefectly healthy.I've noticed symptoms tend to worsen when I eat a lot of fat. It's like the accutane reactivates the days after.

Does anyone recognize this? I'm getting desperate for some relief. Eye drops don't do much. I use them during the day/night to prevent any further damage to my eyes.

You:
I've noticed symptoms tend to worsen when I eat a lot of fat. It's like the accutane reactivates the days after.

------------

Me:
Your symptoms get worse when you eat fat because that triggers bile to be released from your liver (along with stored accutane) and you reabsorb the bile as well as the accutane back into your body.

Sea buckthorn oil is great for the eyes.

" I'm forever grateful to this forum for helping me find the right method to treat my dry eyes. I was reading through every thread in the 'Dry Eye Triumphs' section, and came across a person who had a very natural yet promising treatment to her problem -- taking a combination of Omega 3 and seabuckthorn oil simultaneously which eliminated her dry eyes completely. She also had a similar condition as me (mid-20s sufferer, mgd, sudden dry eyes overnight, etc), though in my case my dry eyes were never as severe as hers.

At first I was a bit skeptical that something so... simple... would work, but I figured that it wouldn't hurt me to try it so I bought Provas Omega 3 (apparently the best Omega 3 in the world?) and Pharma Nord Omega 7 seabuckthorn oil and took double dosages for two weeks. Miraculously, within 3 days I could feel my symptoms reduce significantly and by one week, 90% of my symptoms were gone. In two weeks, I stopped using my eyedrops completely! I still can't believe it, I don't have dry eyes anymore!

My dry eyes were triggered from past usage of Accutane (which I took 5 years ago but only started getting dry eyes a few months ago), which probably wrecked havoc on my oil glands. I reckon the Omega 3 and 7 helped increase oil secretions in my eyelids? Don't really understand the mechanics but all I know it worked for me. And even though I don't feel the symptoms anymore, I'll still continue to take the capsules from now on, just so I won't relapse again.

The Dry Eye Triumphs section is definitely a life saver, I'd recommend anyone to take a walk in the threads and seek out something that would work for them. Don't lose hope!

- Fatin"

Great brand:

1 hour ago, yetanotheraccutanevictim said:

You:
I've noticed symptoms tend to worsen when I eat a lot of fat. It's like the accutane reactivates the days after.

Interesting to read that. Back in June I had a few days of massively improved side effects (sexual sides were 80% back to normal), which was after I'd been [very] ill with a binary duct obstruction.

I was basically feeling horrendous about 45-60 minutes after eating a meal with fat in. Racing heart, feeling really faint and shaky, like I was being poisoned - also very bad anxiety. As soon as I realised it was being triggered by eating fat, i stopped eating fat and just ate jacket potato, sauerkraut, quorn mince (a meat-free mince), yoghurt (1% fat) with prunes. This went on for about a week or so, and in the end I got an ultrasound and x-ray which were both clear, but my blood was acidic so clearly something had been very wrong. Obviously caught just the end of it, and it hasn't re-occured.

The sides returned after I started eating fat again, but I bought a load of coconut oil soon after as that doesn't trigger a release of bile, and planned to do 10 days or so virtually fat free, but haven't done so yet.

Has anyone tried fat-free/almost fat free diets for a time?!

3 hours ago, tanedout said:

Interesting to read that. Back in June I had a few days of massively improved side effects (sexual sides were 80% back to normal), which was after I'd been [very] ill with a binary duct obstruction.

I was basically feeling horrendous about 45-60 minutes after eating a meal with fat in. Racing heart, feeling really faint and shaky, like I was being poisoned - also very bad anxiety. As soon as I realised it was being triggered by eating fat, i stopped eating fat and just ate jacket potato, sauerkraut, quorn mince (a meat-free mince), yoghurt (1% fat) with prunes. This went on for about a week or so, and in the end I got an ultrasound and x-ray which were both clear, but my blood was acidic so clearly something had been very wrong. Obviously caught just the end of it, and it hasn't re-occured.

The sides returned after I started eating fat again, but I bought a load of coconut oil soon after as that doesn't trigger a release of bile, and planned to do 10 days or so virtually fat free, but haven't done so yet.

Has anyone tried fat-free/almost fat free diets for a time?!

7

Thanks so much for sharing. Others please share your experiences if this is the case for you as well.

A no-fat diet WILL NOT cure us. It will just temporarily prevent accutane from coming out of the liver into the intestines.
The cure is liver-gallbladder flushing, coffee enemas, urine therapy or homeopathy, and eating plenty of pastured liver.

Eating less fat for me didn't do much. At first I thought I had discovered something, maybe NAFLS, however liver function tests seemed to disprove this. Now I'm testing for SIBO, and a lactose intolerance. Primarily interested in GUT health at the moment. 

Yet, I have taken allochol, a Russian made bile stimulant that according to what I've read and watched is meant to trigger huge bile dumps. I've taken 8 tablets a day for over 2 weeks now and had no reaction?? Bile flow or the gallbladder is defiantly a key factor in our diminished health. 

Have also read a study from 2011 I beleive that links accutane to jump starting a gluten intolerance. So will test for that next. When I consume large amounts of gluten I have considerably noticeable symptoms

38 minutes ago, Iamme. said:

Eating less fat for me didn't do much. At first I thought I had discovered something, maybe NAFLS, however liver function tests seemed to disprove this. Now I'm testing for SIBO, and a lactose intolerance. Primarily interested in GUT health at the moment. 

Yet, I have taken allochol, a Russian made bile stimulant that according to what I've read and watched is meant to trigger huge bile dumps. I've taken 8 tablets a day for over 2 weeks now and had no reaction?? Bile flow or the gallbladder is defiantly a key factor in our diminished health. 

Have also read a study from 2011 I beleive that links accutane to jump starting a gluten intolerance. So will test for that next. When I consume large amounts of gluten I have considerably noticeable symptoms

 

SIBO testing is worthless. If you have SIBO, it's because of poor bile flow. Your liver is clogged if you have poor bile flow.
Liver health determines gut health. Liver health determines overall health.

Accutane can jump start a gluten intolerance because it messes up the liver.
Parasites can cause a gluten intolerance.  https://www.ncbi.nlm.nih.gov/pubmed/1885068
Accutane messes up liver which results in poor gut health. Poor gut health results in poor immunity.
Poor immunity allows parasites to flourish
Parasites = food intolerances, allergies, and poor absorption of nutrients & minerals

Also, be sure it's not glyphosate instead of the gluten. You could just be eating non-organic grains and reacting to the RoundUp (glyphosate) herbicide (is the most toxic poison on the planet almost).

If reacting to organic grains, it could be that they aren't the ancient kind of grains that we are evolved for (like einkorn or emmer).

*I feel sorry for the folks who won't do liver-gallbladder flushes & coffee enemas. They are the keys to recovery.
 

Gastroenterologist has put me on:
Rifaximin
Vancomycin

One week in and no noticeable results - so fucken disappointed. He said after this we might need to do a poo transplant - whatever the fuck that involves I couldn't tell you. This is all in relation to gut health improvement. This is all well and good but if our problems are liver related than I'm wasting my time. At this point in time I'll try anything as I can't feel worse!

Im so tired that I want go on LDN to see what happens but right now I can't overload on too much. I have to be on the antibiotics for 2 months to see it through.

Should I do more liver flushes? - probably. Like I've said before, I'm on track for starting my real life at 60!!

I have to agree with yetanotheraccutanevictum. I met with a Chinese herbalist a month ago and he told me he has seen many many patients over the years with accutane side effects. He said the main thing you have to fix is the liver. The stuff he knew about the drug blew my mind. He did say that liver flushes and coffee enemas are good but that you need herbs to rebalance the liver. The first 10 days on the herbs I felt incredibly good and my oil was starting to come back in my face and stools went dark again but then after 10 days things kind of went back to normal. He told me to give him 2 months and he thinks I'll be feeling a lot better.

The herb is xiao yan san by KPC herbs. He also has me on a liquid mixture of Solomon's seal, Oregon grape, dandelion, milk thistle, burdock root.

Oh and he said the drug is absolutely still in your body. It's in your joints, tissues ect... It all goes back to that video that was posted saying if you have side effects it means the drugs still in the body.

4 hours ago, yetanotheraccutanevictim said:

SIBO testing is worthless. If you have SIBO, it's because of poor bile flow. Your liver is clogged if you have poor bile flow.
Liver health determines gut health. Liver health determines overall health.

Accutane can jump start a gluten intolerance because it messes up the liver.
Parasites can cause a gluten intolerance. https://www.ncbi.nlm.nih.gov/pubmed/1885068
Accutane messes up liver which results in poor gut health. Poor gut health results in poor immunity.
Poor immunity allows parasites to flourish
Parasites = food intolerances, allergies, and poor absorption of nutrients & minerals

Also, be sure it's not glyphosate instead of the gluten. You could just be eating non-organic grains and reacting to the RoundUp (glyphosate) herbicide (is the most toxic poison on the planet almost).

If reacting to organic grains, it could be that they aren't the ancient kind of grains that we are evolved for (like einkorn or emmer).

*I feel sorry for the folks who won't do liver-gallbladder flushes & coffee enemas. They are the keys to recovery.

And yet my liver function tests returned normal results, as do many who suffered accutanes aftermath?

How many flushs/CE's have you done?

Id love to see results from anyone who has completed 30+ flushes, hundreds of CE's, herbs and every possible attempt to restore liver and even gallbladder health.