Hi everyone, I'm new here & am considering starting accutane... But after reading through this forum I am getting some serious second doubts...

Is accutane worth it? My brother and dad both took it without side effects (besides joint pain).

I don't want to suffer from long-lasting side effects such as depression or ED (if they are not quickly cureable).

Advice would be greatly appreciated!

It's frustrating isn't it. I remember the biggest test you had to have whilst on tane was with the liver. At the time results came back fine and yet tests since then have indicated at various times everything from raised enzyme levels to fatty liver!!??

Half these blood tests are total bullshit and inconclusive. Over the last 12 months I've been jumping one week to the next thinking this is all gut related then the next week it's liver. At the moment everything I'm working on is gut related but then someone gets on forum bringing up liver and I think yeah makes sense it's a liver/bile issue, that's what I've got to get on top of.

I also think or at least want to believe that any brain fog isn't damage as such but is just a result of bad fatigue and sluggish immune system, nothing more.

Next week someone will bring up parasites again and I'll go yeah yeah I've just got a candida problem. Who the hell would know!!??

I don't really buy the theory that 'accutane is still in the body'. I hardly took any, and some have taken just a single capsule and ended up with persistent sides. Is there supposed to be an unlimited store in the liver that just travels around the body, getting involved with many biochemical processes, but somehow not changing it's structure at all, and just going round and round? Even if some was stored in fat cells, it would only recirculate when you lost weight and those cells broken down for energy. It's just not feasible that sides many years later are due to accutane in the body.

IMO the root cause is impaired methylation, and everything is a consequence of this, and a down-stream effect.

I've tried tackling gut issues by getting gastrointestinal tests done (confirming a lack of certain specifies of good bacteria), and have taken probiotics for months to try and replenish the lacking species - eaten sauerkraut and kefir milk for months, while minimising sugar, got hold of a lot of 'Mutaflor' probiotic to try and replenish my 'good e.coli' species, along with many other probiotics such as 'prescript assist' etc but none of this really helped, because the issue is up-stream, however clearly poor gut health is not helping matters (in terms of absorbing nutrients), so it will always be important to try and promote good gut health.

Same goes for the liver, clearly there are issues there, but again due to methylation resulting in impaired function, however this is also a reason to try not to overburden it.

http://howirecovered.com/connections-between-methylation-toxicity-and-liver-function/

That's why I think the best route to trying to overcome sides is getting methylation working again properly. This isn't an easy one-size fits all approach, it's trial and error involving various supplements in differing amounts. Elevated homocysteine seems to be a real indictor of impaired methylation, anyone actually got test results for this?

Besides homocysteine levels what else does one check for methylation function??

I know B12 is important but recent blood work for me indicated B levels were fine.

I was curious to know if methylfolate supplement has worked for anyone but no one responded so I'll assume it hasn't been tried by anyone!!??

Certainly many of the conditions mentioned with poor methylation ring very true with what we all suffer from so yeah I'd agree we need the look at it. The only thing id say is - it's possible that at the same time we still have liver issues, gut health problems etc, so do you work on everything at once or tackle methylation first followed by gut followed by liver??

What causes methylation to get out of wack anyway??....besides tane

6 hours ago, Iamme. said:

And yet my liver function tests returned normal results, as do many who suffered accutanes aftermath?

How many flushs/CE's have you done?

Id love to see results from anyone who has completed 30+ flushes, hundreds of CE's, herbs and every possible attempt to restore liver and even gallbladder health.

Conventional lab testing is almost useless. However, if your AST or ALT is higher than 12 IU/L, you have liver problems most definitely.
If total bilirubin is higher than 1 mg/dL, you have liver problems most definitely.
If indirect bilirubin is higher than 0.8 mg/dL, you most likely have liver problems.
Sidenote: if Parathyroid Hormone is higher than 30 PG/mL, you are vit D deficient.

I've done 16 liver-gallbladder flushes and many dozens of coffee enemas.
I WILL NOT be able to heal myself without these therapies. I have made significant progress with them.
Read below to find out why I'm not cured yet (parasites).

4 hours ago, TrueJustice said:

It's frustrating isn't it. I remember the biggest test you had to have whilst on tane was with the liver. At the time results came back fine and yet tests since then have indicated at various times everything from raised enzyme levels to fatty liver!!??

Half these blood tests are total bullshit and inconclusive. Over the last 12 months I've been jumping one week to the next thinking this is all gut related then the next week it's liver. At the moment everything I'm working on is gut related but then someone gets on forum bringing up liver and I think yeah makes sense it's a liver/bile issue, that's what I've got to get on top of.

I also think or at least want to believe that any brain fog isn't damage as such but is just a result of bad fatigue and sluggish immune system, nothing more.

Next week someone will bring up parasites again and I'll go yeah yeah I've just got a candida problem. Who the hell would know!!??

Gut health is dependent upon liver health. Overall health is dependent upon liver health. I saw this having researched this particular issue for over 1000 hours.
Brain fog is from toxicity. No question about it. Fatigue is from immune hyperactivation which is from toxicity or pathogens. And toxicity can include antigens leaking into the blood from the gut. Fixing the liver fixes this issue.

By the way, I found out by zapping with Ken Presner's Ultimate Zapper QE2 model that I am INFESTED with large worms. Rope worms and ascarisroundworms. I can feel them in my liver, intestines, and muscles the night of me zapping. They are excreted the next morning.

Am starting turpentine, MMS (chlorine dioxide), colloidal silver, and a few other things really soon. Zapping with that zapper will most likely be plenty, though.

42 minutes ago, tanedout said:

I don't really buy the theory that 'accutane is still in the body'. I hardly took any, and some have taken just a single capsule and ended up with persistent sides. Is there supposed to be an unlimited store in the liver that just travels around the body, getting involved with many biochemical processes, but somehow not changing it's structure at all, and just going round and round? Even if some was stored in fat cells, it would only recirculate when you lost weight and those cells broken down for energy. It's just not feasible that sides many years later are due to accutane in the body.

IMO the root cause is impaired methylation, and everything is a consequence of this, and a down-stream effect.

I've tried tackling gut issues by getting gastrointestinal tests done (confirming a lack of certain specifies of good bacteria), and have taken probiotics for months to try and replenish the lacking species - eaten sauerkraut and kefir milk for months, while minimising sugar, got hold of a lot of 'Mutaflor' probiotic to try and replenish my 'good e.coli' species, along with many other probiotics such as 'prescript assist' etc but none of this really helped, because the issue is up-stream, however clearly poor gut health is not helping matters (in terms of absorbing nutrients), so it will always be important to try and promote good gut health.

Same goes for the liver, clearly there are issues there, but again due to methylation resulting in impaired function, however this is also a reason to try not to overburden it.

http://howirecovered.com/connections-between-methylation-toxicity-and-liver-function/

That's why I think the best route to trying to overcome sides is getting methylation working again properly. This isn't an easy one-size fits all approach, it's trial and error involving various supplements in differing amounts. Elevated homocysteine seems to be a real indictor of impaired methylation, anyone actually got test results for this?

Methylation is downstream. Ask yourself why is methylation not correcting itself. Something is continuing to mess it up (infections, toxins like accutane, and a clogged liver).

I can't keep answering peoples' questions. I'm sorry. I recommend researching things I've mentioned in my posts. Good luck.
If you REALLY need a response, private message me with short questions.

12 minutes ago, yetanotheraccutanevictim said:

Conventional lab testing is almost useless. However, if your AST or ALT is higher than 12 IU/L, you have liver problems most definitely.
If total bilirubin is higher than 1 mg/dL, you have liver problems most definitely.
If indirect bilirubin is higher than 0.8 mg/dL, you most likely have liver problems.
Sidenote: if Parathyroid Hormone is higher than 30 PG/mL, you are vit D deficient.

I've done 16 liver-gallbladder flushes and many dozens of coffee enemas.
I WILL NOT be able to heal myself without these therapies. I have made significant progress with them.
Read below to find out why I'm not cured yet (parasites).

Gut health is dependent upon liver health. Overall health is dependent upon liver health. I saw this having researched this particular issue for over 1000 hours.
Brain fog is from toxicity. No question about it. Fatigue is from immune hyperactivation which is from toxicity or pathogens. And toxicity can include antigens leaking into the blood from the gut. Fixing the liver fixes this issue.

By the way, I found out by zapping with Ken Presner's Ultimate Zapper QE2 model that I am INFESTED with large worms. Rope worms and ascarisroundworms. I can feel them in my liver, intestines, and muscles the night of me zapping. They are excreted the next morning.

Am starting turpentine, MMS (chlorine dioxide), colloidal silver, and a few other things really soon. Zapping with that zapper will most likely be plenty, though.

Methylation is downstream. Ask yourself why is methylation not correcting itself. Something is continuing to mess it up (infections, toxins like accutane, and a clogged liver).

I can't keep answering peoples' questions. I'm sorry. I recommend researching things I've mentioned in my posts. Good luck.
If you REALLY need a response, private message me with short questions.

I appreciate the posts coming from many of you who obviously do your research and know more than I do!!

One thing I do believe I'm right about though is that we all must work on problems similataneaosly, we know that tane potentially messed up the whole body. So in turn you must work on gut whilst working on liver whilst working on methylation etc etc, can't just concentrate on one area.

I think most of us who've tried to work on brain/mental conditions with supplements or perscription drugs have been disappointed in the results, WHY - because the liver and gut are still fucked!!!

51 minutes ago, TrueJustice said:

Besides homocysteine levels what else does one check for methylation function??

I know B12 is important but recent blood work for me indicated B levels were fine.

I was curious to know if methylfolate supplement has worked for anyone but no one responded so I'll assume it hasn't been tried by anyone!!??

Certainly many of the conditions mentioned with poor methylation ring very true with what we all suffer from so yeah I'd agree we need the look at it. The only thing id say is - it's possible that at the same time we still have liver issues, gut health problems etc, so do you work on everything at once or tackle methylation first followed by gut followed by liver??

What causes methylation to get out of wack anyway??....besides tane

B12 levels often test fine on a blood test, but people will CFS seem to have a deficiency in cerebrospinal fluid levels, and do much better when they're taking high doses of ACTIVE B12, not the forms you get in cheap multivits. 

Posted up before a few times, but people with similar conditions to ours (CFS namely) generally see improvements when they follow methylation protocols. This [acne.org] thread has many people posting up all sorts of  theories, but few actually get any real benefits from them. CFS forums have hundreds if not thousands following the similar protocols regards to methylation, with the majority getting at least some benefit (based on user polls I've seen on phoenix rising)

Try and read this whole thread, it contains many useful links too

http://howirecovered.com/active-b12-therapy-faq/

Regards methylfolate, I've started taking 1000mg/day now as I've been doing fine on 2000mg/day of methylB12 for a while, with improved mental clarity. 

From the link above, this is an extract regards gut issues;
 

Quote

 

Should I fix my digestive issues before starting methylation?

velha508: I have gut issues “ which I am currently working on. I worked on my methylation cycle first because 

1) I could not think clearly prior to getting my methylation cycle going 

2) The methylation block is likely the reason for the gut issues in the first place “ that is, contributes to the cascade of events that leads one to end up with dysbiosis (I think anyway). While some may think the opposite is true “ once you are in a CFS state your body will not have the energy needed to heal and maintain a healthy gut if you have a methylation block. 

3) Getting it going helped and is helping with clearing up my gut issues. With little effort on my part my digestive system has started to come around on it™s own after 4 months on Freddd™s protocol. 

I read Myhill™s whole approach about building a house from the ground up and I felt that the foundation was lifting the ˜methylation block™, not fixing my gut¦ Sunday: I™ve been on the methylation protocol for about 4 months. A few weeks ago, my constant nausea stopped. (Warning: it did get much worse on the B12s before it went away. This seems to be a pattern with my B12 reactions; a symptom gets worse for some weeks, then disappears or is reduced drastically. I still have the occasional bout of nausea, but it isn™t constant. So nice.)

Also, I have started digesting foods more normally, absorbing more of their nutrients. How do I know without extensive testing? Well, for the last year I lost weight no matter what I ate. Now I have started to gain it (never thought I™d be happy about that!). I™m also responding to foods and supplements more as I used to (e.g., I feel a boost of energy after eating protein; my mind clears when take a ginkgo biloba supplement), although I™m nowhere near back to my pre-CFS responses. And my elimination, which used to swing between diarrhea and constipation, is now easy and normal (that got more extreme, too, before it healed). 

My experience is that methylation IS the basis of at least a lot of my gut issues. I agree with velha, you might want to consider doing this as the basis of your gut healing, or along with other gut-healing stuff. Or at least just keep it in mind as you proceed. richvank: The best treatment sequence is not easy to determine even if one knows the sequence in the pathogenesis, because there can be interactions.

For example, the development of a partial methylation cycle block may be what leads to the gut dysfunction in many cases. However, when the gut dysfunction has developed, it can lead to poor digestion and absorption of substances that are important to get the methylation cycle running again, such as amino acids. So even though the methylation cycle block may have led to the gut dysfunction, it may be necessary in some cases to work on the gut first. In other cases, the gut may still be working well enough to bring in enough of the essential nutrients, and in those cases, of which yours might be two, fixing the methylation first works well.

Yesterday I had a conversation with Dr. Richard Kunin, the president of the Orthomolecular Health-Medicine Society, a person who has studied methylation issues for many years. He pointed out to me that when methylation goes down, one of the first things to suffer is the exocrine pancreas function, i.e. the part of the pancreas that normally produces digestive enzymes. I did a little literature searching, and he appears to be right. That might be one way (or maybe it™s THE way) that a partial methylation cycle block leads to gut dysfunction.

When you can™t digest food for lack of digestive enzymes, I think the bacteria are going to respond by consuming the food and overgrowing. This may account for low chymotrypsin or pancreatic elastase in some of the stool tests from PWCs that I™ve seen. In the past, I™ve suspected that this might be due to low stomach acid production, which would lead to lack of a signal to excrete the digestive enzymes from the pancreas when the food moves into the duodenum. But maybe the problem really is with the pancreas itself, because of the methylation cycle block. velha: My gut shut down at the same time I became very ill “ July/August 09. Digestion just stopped. So, mine has been short term also. 

It is hard to say what has helped my gut the most. I can say the I noticed no effect with increasing doses of mB12 and methylfolate (at least not immediate). My gut began to improve in late December. I did a number of things at that time, two being increasing my adB12 (to daily) and carnitine dosages (~4g/day). Suzy: I just wanted to share another possible reason for improvement of gut function on Rich™s or Freddd™s protocol. This abstract shows that oxidative stress can lead to pancreatitis and Rich™s protocol has been shown to raise glutathione in his study.

Superoxide dismutase and catalase: a possible role in established pancreatitis.
Guice KS, Miller DE, Oldham KT, Townsend CM Jr, Thompson JC.

The mechanism of cerulein-induced acute pancreatitis may involve the production of free radicals in excess of the capacity of endogenous intracellular scavengers. These radicals destroy the cellular membranes, releasing digestive enzymes and cellular proteins into the interstitium. Thereafter, a cascade of events, including polymorphonuclear infiltration and complement activation, leads to pancreatic destruction.

The present study demonstrates that superoxide dismutase and catalase reduce the ultrastructural and biochemical injury associated with cerulein-induced acute pancreatitis in rats. Pretreatment with superoxide dismutase and catalase 30 minutes before injury did not appear to be protective, presumably because the half-life of intravenous superoxide dismutase is only 6 minutes. This and similar studies suggest a potential clinical role for free radical scavengers in acute established pancreatitis.

 

46 minutes ago, TrueJustice said:

One thing I do believe I'm right about though is that we all must work on problems similataneaosly, we know that tane potentially messed up the whole body. So in turn you must work on gut whilst working on liver whilst working on methylation etc etc, can't just concentrate on one area.

4

Working on the liver is the key to restoring ANY area in the body. If you improve liver health, you improve gut health, brain health, eye health, toenail health, etc.. EVERYTHING. Please listen to my advice and focus all your attention on the liver, detoxification, and killing pathogens

I agree. Need to work on all areas. I forgot to mention that I also do take a b vitamin with the active form of folate because I have the MTHFR gene. I do not have high homocysteine. Chinese herbalist said you need to continue with the b vitamins for rest of life.

4 hours ago, Chris16 said:

I agree. Need to work on all areas. I forgot to mention that I also do take a b vitamin with the active form of folate because I have the MTHFR gene. I do not have high homocysteine. Chinese herbalist said you need to continue with the b vitamins for rest of life.

Don't take B complexes daily as it can feed infections. They use them as substrate for their metabolism.
I'd take it once a week.
If you eat plenty of raw vegetables, you get loads of B vits.

And food-based forms of supplements are best. The ratios between nutrients, phytonutrients, minerals, trace elements, anti-oxidants, etc.. matters greatly. That's one of the reasons accutane messed us up so bad. It threw our fat-soluble "vitamins" ratio off. We need to get TONS of sunshine now to rebalance the vit A to D. Also, eat plenty of vit K2 containing foods. Sauerkraut with Mercola's Kinetic culture probiotic is best.

1 hour ago, yetanotheraccutanevictim said:

Don't take B complexes daily as it can feed infections. They use them as substrate for their metabolism.
I'd take it once a week.
If you eat plenty of raw vegetables, you get loads of B vits.

The problem is that the form of B vitamins found in foods can be counterproductive for those of us with MTHFR mutations. The body cannot convert the vitamins properly no matter how healthy one's diet is. That being said, as someone with MTHFR mutations, I noticed no digestive or cognitive changes after supplementing with the active form of folate and B12 for two months. Perhaps I'll give it another go later.

Those well-versed in MTHFR mutation research seem to give highly specific advice based on each individual, genetic mutation. I should probably look into more. If I could pay someone to make sense of all of my mutations related to vitamin metabolism, I'd do it. Some of the advice attached to each mutation directly contradict what I should do in regards to another mutation. I don't know what to believe.

4 hours ago, ACCUiTy_drANE said:

The problem is that the form of B vitamins found in foods can be counterproductive for those of us with MTHFR mutations. The body cannot convert the vitamins properly no matter how healthy one's diet is. That being said, as someone with MTHFR mutations, I noticed no digestive or cognitive changes after supplementing with the active form of folate and B12 for two months. Perhaps I'll give it another go later.

Those well-versed in MTHFR mutation research seem to give highly specific advice based on each individual, genetic mutation. I should probably look into more. If I could pay someone to make sense of all of my mutations related to vitamin metabolism, I'd do it. Some of the advice attached to each mutation directly contradict what I should do in regards to another mutation. I don't know what to believe.

MTHFR is overhyped. Biochemical polymorphisms are useless compared to epigenetic influences. Physics is the answer. Biochemistry / Biology is not a fundamental science. Physics explains why the chemicals of lifedo the things they do at the most microscopic levels.

It's about the environment primarily, not your genes.

Again, if someone here is suffering and has not tried MMS, turpentine from diamondgforestproducts, colloidal silver, urine therapy, or zapping, WHAT ARE YOU WAITING FOR? Danny Glass (Sun Fruit Dan youtube channel) actually has a lot of decent videos where he gives quick overviews of some of these therapies. Will save you the long route of researching them yourself.

Positive for SIBO, not just candida. REally going HAM on this with enteric coated peppermint oil, SF722 formula, bone broth, glutamine, etc. I'm already more hydrated on a daily basis. CBN night oil is putting me to sleep, and CBD is helping saturate my tissues and joints. FEeling better little by little. Very slow progress, but noticeable. Been doing methylation now for almost 8-9 months. It helps with mental clarity and joint pain. I'm doing other things as well but am just too lazy to detail everything. Taking LDN for past 2-3 years. Anyone else have SIBO Dx? I've been slacking on liver flushes, did 10 and was still passing things, so I genuinely believe I'm still very congested still.

1 hour ago, yetanotheraccutanevictim said:

MTHFR is overhyped. Biochemical polymorphisms are useless compared to epigenetic influences. Physics is the answer. Biochemistry / Biology is not a fundamental science. Physics explains why the chemicals of lifedo the things they do at the most microscopic levels.

It's about the environment primarily, not your genes.

Again, if someone here is suffering and has not tried MMS, turpentine from diamondgforestproducts, colloidal silver, urine therapy, or zapping, WHAT ARE YOU WAITING FOR? Danny Glass (Sun Fruit Dan youtube channel) actually has a lot of decent videos where he gives quick overviews of some of these therapies. Will save you the long route of researching them yourself.

I just need to ask, how have you concluded that you need to take all these things to get results??
Why not just the MMS alone?

Thats what is confusing about this forum, everyone is quick to say take this and do that but how do you know what to eliminate along the way?

Ive tried colloidal silver - by itself nothing happened.

Like the post about Xiao Yao San and it helping the liver. Why isn't that alone good enough to work on liver? Who concluded you also need to take milk thistle and Solomon's seal etc??

Its all hit and miss as far as I'm concerned.

Hey everyone. Good stuff. Lots of good ideas being thrown out. We just need some people to start improving and seeing some success. Does anyone else have an extremely dry face still? I've been off accutane for 2 years and the worst part now is my extreme facial blushing and flushing that actually seems to be getting worse. Anyone else have a problem with that? Anyone do anything to fix or improve it? Any experience or help or advice would be greatly appreciated!

Anyone have these done?

Been advised to have this tests.
urinary organic acids.

also interested in the Fatty Acid Profile

3 hours ago, helpmeoutbuddies11 said:

Hey everyone. Good stuff. Lots of good ideas being thrown out. We just need some people to start improving and seeing some success. Does anyone else have an extremely dry face still? I've been off accutane for 2 years and the worst part now is my extreme facial blushing and flushing that actually seems to be getting worse. Anyone else have a problem with that? Anyone do anything to fix or improve it? Any experience or help or advice would be greatly appreciated!

Yes I still have this problem after 15 years. I have no clue how to fix this.

On 9/23/2016 at 1:15 PM, yetanotheraccutanevictim said:

On 9/23/2016 at 0:28 PM, TrueJustice said:

One thing I do believe I'm right about though is that we all must work on problems similataneaosly, we know that tane potentially messed up the whole body. So in turn you must work on gut whilst working on liver whilst working on methylation etc etc, can't just concentrate on one area.

4

Working on the liver is the key to restoring ANY area in the body. If you improve liver health, you improve gut health, brain health, eye health, toenail health, etc.. EVERYTHING. Please listen to my advice and focus all your attention on the liver, detoxification, and killing pathogens

yetanotheraccutanevictim - Hey, how did you conclude liver level? Bilirubin 4 umol/L (range 3 -20) serum ALT 23 IU/L (range5 -55)
Are you saying these numbers indicate a problem.

interestingly Albumin 48 (range 35 -50g/L)

13 hours ago, TrueJustice said:

I just need to ask, how have you concluded that you need to take all these things to get results??
Why not just the MMS alone?

Thats what is confusing about this forum, everyone is quick to say take this and do that but how do you know what to eliminate along the way?

Ive tried colloidal silver - by itself nothing happened.

Like the post about Xiao Yao San and it helping the liver. Why isn't that alone good enough to work on liver? Who concluded you also need to take milk thistle and Solomon's seal etc??

Its all hit and miss as far as I'm concerned.

Each one of the remedies I shared has the potential toheal us completely by itself. However, EVERYONE here should be doing coffee enemas and liver-gallbladder flushes in addition to one other SUPER powerful therapy like turpentine or MMS, etc..
And colloidal silver is probably the weakest of the things I've shared but it's still excellent. Brand matters.
It's not hit or miss tactics. Just do as many things as possible. Don't do ONE single thing like colloidal silver and hope to get well.

1 hour ago, hatetane said:

yetanotheraccutanevictim - Hey, how did you conclude liver level? Bilirubin 4 umol/L (range 3 -20) serum ALT 23 IU/L (range5 -55)
Are you saying these numbers indicate a problem.

interestingly Albumin 48 (range 35 -50g/L)

A few hundred hours of research. Yes, your liver is under stress and most likely congested. My numbers are lower than yours and my liver is almost completely clogged.

I really need some suggestions! I have been on Accutane for two months now and now am getting joint pains. Some people are suggesting omega 3 some are suggesting glucosamine. Can someone give me some suggestions on it?

2 hours ago, Sincere1212 said:

I really need some suggestions! I have been on Accutane for two months now and now am getting joint pains. Some people are suggesting omega 3 some are suggesting glucosamine. Can someone give me some suggestions on it?

Stop taking it is my best suggestion for you.

I have a dry face as well, and dry body, etc.  I don't get the flushing that everyone talks about though which is weird.  I get the opposite, lack of blood flow to the face.  I literally have to hang upside down to get blood into my head, face, and scalp.  Worst circulation goes to ME!

It's been much  better with exercise and CBD oil

6 hours ago, MovingOnMusicGal said:

I have a dry face as well, and dry body, etc.  I don't get the flushing that everyone talks about though which is weird.  I get the opposite, lack of blood flow to the face.  I literally have to hang upside down to get blood into my head, face, and scalp.  Worst circulation goes to ME!

It's been much  better with exercise and CBD oil

Where do you get CBD oil from?
Any brands you can recommend?

In relation to your dry face - do you put CBD oil on it? or do you use it just on the body?

My circulation is horrendous too, plus I have bad varicose veins. On top of the eye floaters and all that crap, I'd say it's all related.

Is it from a clogged liver??

On 02.03.2016 at 10:57 PM, MrErdem said:

2 years passed since my last pill. I took 40mg/day for two months in 2014 Jan/Feb..
This is the list of my problems:
-ED: Still no connection between penis and brain. Improved maybe %40 where I can achieve an erection but sensation got worse. I used to be very horny, now I am half the man I used to be (good song btw). My flaccid state is horrible. My orgasms got worse where I dont feel anything during ejaculation. 
- Tinnitus: still there
- Vision problems: floaters are gone by 90%. But I am still night blinded and have some visual snow and double vision. Not a big deal, can live with these.
- Tremors: gone by 99%
- Weak urine: still bothering me but ok.
- Hair: still thin and dry and I lost lots of hair, but I am still not bald and it stopped.
- Dry eyes, nose, mouth: I never had these, it is interesting that some sympthoms are not the same.
- Panic attacks, anxiety, suicidal state: gone, I feel depressed sometimes but mental I am pre-accutane
- Energy: Better %70
- Flexibility: I feel like an old man, I dont prefer to yawn. It hurts. But improved %40
- Stomach: my new problem, reflux and gastrit started 6-7 months ago.

Overall I am Ok. Soon I will start gym, I feel I can do it : )
But my biggest problem is the absence of libido. I just dont have it. When I see an attractive woman, i know that she is hot but I don't feel it. I want to feel like a man again. I think I will try Clomid and see if it works.

 

Ok, now it has been 6 months since I started gym. The best thing ever. I encourage everybody start moving. Just do it! 
But:
No matter hard I try, no matter I go every other day to gym, or everday, or sleep or nutrition.. I can not get in shape!
Nobody believes me that I go to gym. I think the androgen insensitivity theory fits to me. I checked my hormonal panel many times, levels are within ranges but on the low side. I tried tamoxifen (only a couple of pills cause I am scared) , tribulus tettretis, zinc, NO boosters, they wont help.  
This is my body shape still after 6 months: 

And this is my case, especialy two boxes on the bottom..

8 hours ago, MrErdem said:

Ok, now it has been 6 months since I started gym. The best thing ever. I encourage everybody start moving. Just do it! 
But:
No matter hard I try, no matter I go every other day to gym, or everday, or sleep or nutrition.. I can not get in shape!
Nobody believes me that I go to gym. I think the androgen insensitivity theory fits to me. I checked my hormonal panel many times, levels are within ranges but on the low side. I tried tamoxifen (only a couple of pills cause I am scared) , tribulus tettretis, zinc, NO boosters, they wont help.  
This is my body shape still after 6 months: 

And this is my case, especialy two boxes on the bottom..

What hormone panel did you get.. and what are the numbers?

Estrogen dominance mimic  the same EXACT  symptoms.    many people on here have had their testosterone numbers tested... soe come back high

its a specific test... im having a complete hormone panel... but you have to order a total estrogen count... not just the male estrodial number.  (you have to get a womens test.)   it would fit with the low libido, SIBO, Candida.

google candida and estrogen dominance (think eye floaters)
SIBO and estrogen dominance

calcium D glucarate    .. our livers are so backed up, that we cant eliminate estrogens the correct way anymore?  Gilberts disease would make it worse.

many people on these forums take DIM and calcium D glucarate for acne.  its mostly women... but the results are astounding.

I3C  indole 3 Carbinol or Zinc would do the same thing.... clear excess androgens and estrogens.

Estrogen and Cholestasis.....  i know we keep going to in circles about glucuronides of accutane being stuck.. but what about Estrogen not being able to be detoxified due to the drug as well?   causing a loop?  

Read these two paragraphs below...  is this why Calcium D Glucarate and UDCA are recommended in the solving the accutance problem video?

Estrogens[edit]

Estrogens, and particularly glucuronides such as estradiol-17²-D-glucuronide, have been shown to cause cholestasis in animal studies, by reducing bile acid uptake by hepatocytes.^[7]

Treatment[edit]

Upon diagnosis, many providers will prescribe Ursodeoxycholic Acid. While there is no cure for ICP, and no way to guarantee a successful outcome, studies have shown a slightly better fetal and maternal outcome from administration of Ursodeoxycholic Acid, whereas Cholestyramine appears to only relieve itching.^[7]

If additional blood tests to check clotting function identify a problem, giving Vitamin K may help avoid the risk of hemorrhage at delivery.

Delivery by 35“37 completed weeks may be important to fetal outcome as a recent study demonstrated that in severe ICP (defined as bile acids greater than 40 umol/L) the risk of stillbirth was 1.5% compared to 0.5% of uncomplicated pregnancies. This risk rose further if bile acids doubled,^[12]

Since estrogen is detoxified the same way as accutane... maybe accutane caused a block here...

http://onlinelibrary.wiley.com/doi/10.1002/hep.1840030422/abstract

So maybe  get a total estrogen test ... even a progesterone test as well.  i know these are for women...but maybe it will show something. (all 3, not just the one   E1 E2  E3) ...

then a treatment of:

Calcium D glucarate
DIM 
Indole 3 Carbinol
TUDCA