6 months use in 2014 of B5 high doses and l-carnitine worsened accutane sides effects, especially sexual problems and muscle mass

i read that b5 in high doses deplete other vitamine B, Bcomplex gave me a small recovery, what happened with high doses of l-carnitine?it is possible to recover at least from this

Accutane ruined many of our lives. We are trying our best with what we have, desperately seeking a cure. As Oli Girl pointed out, this thread VERY CLEARLY implies that it is for those struggling with severe side effects after taking the drug. It has helped some, and for those who are fortunate, that is great. My brother is one of those people. But please, get off of this forum. You have no place here unless you have something to contribute. Every time someone comes on here and provides the same "Accutane revelation" it invalidates all of us as a community and contributes to the despair associated with side effects. I want to say so many other things, but alas, that wouldn't be nice.

this discussion speak about accutane damage not other medication...

no before accutane my life was not ruined! before my c*** worked very well, now NO!!! stop bullshit

read this topic, you don't understand us life with these sides

@idiot who states"Your life was also ruined before accutane too because of acne. This kind of stuff happens alot with other prescription medications, not just accutane."

Stop projecting your feelings onto others. YOU ARE INCORRECT. Everyone here is unique. I had mild acne, could have easily lived with it. Many teenagers have mild acne. I ran varsity track and XC, and that was taken away from as well as my youth. A stupid hack-job of a dermatologist prescribed me something that he shouldn't have due to being a bad doctor. I didn't have cystic acne/never did, which I am fortunate for. But now I have a slue of other problems. You are just offending people here. So please leave.

Is there someone who can moderate this? Kick this person out?

Looking back my acne wasn't bad at all either. I just wanted "perfect" skin. Meanwhile I was living off of frozen pizzas, ice cream and fast food. What kills me is that right before I was going to take Accutane I read about the connection between diet and acne. I decided I would ask my derm. about this connection and that would be my final deciding factor on whether or not to take Accutane. When I brought it up she said "As a doctor, I am telling you there is no link between diet and acne". So I agreed to try Accutane (the antibiotics weren't working). Speaking for myself this is total bullshit.I had too much trust and respect for doctors. I was very ignorant.My skin is clear, but if I eat sugary foods or consume dairy I break out - every time. Eat clean and back to clear skin. I realize not all people can control acne through just diet but it seems the majority of mild to moderate acne can be. But where is the money in that? 9 years later and here I am spending my free time looking for clues to get my health back on acne forums!

Great video I just found:

short summary I typed up:
The key to getting rid of accutane based side effects is to cure both bile flow issues and successfully remove excess Accutane out of the body. These two things both have to happen before your side effects can be stopped.

Reduce the load of crammed bile caused by cholestasis by supplementing with
bile acids
ox bile
granulated lecithin
chinese bitters

TUDCA on a regular basis to regenerate the cells in the liver and saves the liver from toxicity
Even helps restore bile flow

Eat natural & clean foods to prevent toxicity build-up

Consider using MSM supplement every day
to prevent hardening and calcification
increases passability of nutrients into the cells

coconut oil - absorption occurs without bile or pancreatic enzymes
allows absorption with fat & fat-soluble toxins. Only 3-4 tbsp needed per day

Calcium-D-Glucarate taken 2x per day can prevent accutane reabsorption

Stay away from retinol until bile flow is well taken care of
People react to vit A bc they have too much retinoic acid in their body than they need. More vit A just pushes the accutane into the blood stream leading to a toxic shock.
Consider slowly building up to a liquid form of Vit A which will stil be easily digested by the body. Since there is not enough bile in the intestines, you won't be able to digest fat-soluble vitamins but when in liquid form, it can be easily be digested. Take it little by little until the body gets used to it. This will help replace accutane in the body.

Supplementing with Vit C every night will alkalinize the body and help the body's anti-oxidant capacities.

---

EDIT: this is why liver flushes cure so many people from accutane side effects. I can even feel the congestion in my liver.

I should also add that Chelidonium majus seems to be powerful for stimulating bile
--

Also a testimionial from a forum user:
and1:
"

and1

Hey, I used to post here and bile flow is also the one thing or the most important thing to get going in order to get healthy. I could write a couple of pages why it is so important, you probably already know. From my understanding the most underappreciated function that bile flow brings online is the elimination of heavy metals. For instance mercury elimination is largely achieved via the bile and you may know how disruptive this mercury is to our system.

What helps to promote bile flow and unplug the bile ducts?

Heavy hitters:

- UDCA, take at your own risk, I have experimented with it and it helped a lot, I posted about it on this forum, so...

- liver flushing, it is in the same league as UDCA as far as my experience goes, but it takes a lot more effort and preparation than swallowing a pill, however in my judgement you have less downside risks

- exercise like jump-roping, rowing, anything that stimulated you gallbladder

All-Stars - They may work best in combination, you have to experiment a little, some may take a few weeks (4-8) until you notice that the color of your feces is gradually normalizing etc. and in consequence you get better, symptoms gradually disappear:

- Silymarin

- TMG/Betain

- NAC

- Taurine

- Liv52

I head very good experiences with TMG, Silymarin and Liv52. I overdosed Liv52. Looked at how bodybuilders like to dose this stuff and than dosed accordingly. Lately I have had great success with NAC, it raises glutathion. I would cycle 1200 to 1800 mg taken throughout the day, highly diluted in water, for 2 to 3 months at a time and than get off for a few months.

I'd recommend against taking anything for longer than 3 months at a time and would advice cycling the supplements.

Breaking the enterohepatic cycle is also very critical, I am still working on this part once your bile flow is back online. Hope this helps."

5 hours ago, yetanotheraccutanevictim said:

Great video I just found:

Top 8 Tips For Reversing Accutane Side Effects

short summary I typed up:
The key to getting rid of accutane based side effects is to cure both bile flow issues and successfully remove excess Accutane out of the body. These two things both have to happen before your side effects can be stopped.

Reduce the load of crammed bile caused by cholestasis by supplementing with
bile acids
ox bile
granulated lecithin
chinese bitters

TUDCA on a regular basis to regenerate the cells in the liver and saves the liver from toxicity
Even helps restore bile flow

Eat natural & clean foods to prevent toxicity build-up

Consider using MSM supplement every day
to prevent hardening and calcification
increases passability of nutrients into the cells

coconut oil - absorption occurs without bile or pancreatic enzymes
allows absorption with fat & fat-soluble toxins. Only 3-4 tbsp needed per day

Calcium-D-Glucarate taken 2x per day can prevent accutane reabsorption

Stay away from retinol until bile flow is well taken care of
People react to vit A bc they have too much retinoic acid in their body than they need. More vit A just pushes the accutane into the blood stream leading to a toxic shock.
Consider slowly building up to a liquid form of Vit A which will stil be easily digested by the body. Since there is not enough bile in the intestines, you won't be able to digest fat-soluble vitamins but when in liquid form, it can be easily be digested. Take it little by little until the body gets used to it. This will help replace accutane in the body.

Supplementing with Vit C every night will alkalinize the body and help the body's anti-oxidant capacities.

---

EDIT: this is why liver flushes cure so many people from accutane side effects. I can even feel the congestion in my liver.

I should also add that Chelidonium majus seems to be powerful for stimulating bile
--

Also a testimionial from a forum user:
and1:
"

and1

Hey, I used to post here and bile flow is also the one thing or the most important thing to get going in order to get healthy. I could write a couple of pages why it is so important, you probably already know. From my understanding the most underappreciated function that bile flow brings online is the elimination of heavy metals. For instance mercury elimination is largely achieved via the bile and you may know how disruptive this mercury is to our system.

What helps to promote bile flow and unplug the bile ducts?

Heavy hitters:

- UDCA, take at your own risk, I have experimented with it and it helped a lot, I posted about it on this forum, so...

- liver flushing, it is in the same league as UDCA as far as my experience goes, but it takes a lot more effort and preparation than swallowing a pill, however in my judgement you have less downside risks

- exercise like jump-roping, rowing, anything that stimulated you gallbladder

All-Stars - They may work best in combination, you have to experiment a little, some may take a few weeks (4-8) until you notice that the color of your feces is gradually normalizing etc. and in consequence you get better, symptoms gradually disappear:

- Silymarin

- TMG/Betain

- NAC

- Taurine

- Liv52

I head very good experiences with TMG, Silymarin and Liv52. I overdosed Liv52. Looked at how bodybuilders like to dose this stuff and than dosed accordingly. Lately I have had great success with NAC, it raises glutathion. I would cycle 1200 to 1800 mg taken throughout the day, highly diluted in water, for 2 to 3 months at a time and than get off for a few months.

I'd recommend against taking anything for longer than 3 months at a time and would advice cycling the supplements.

Breaking the enterohepatic cycle is also very critical, I am still working on this part once your bile flow is back online. Hope this helps."

Excellent post here about cleaning liver and gallbladder - I like the supplements you've mentioned and the way to go about detoxing!!

However, correct me if I'm wrong but none of these supplements will do much for parasites and infections which many people posting here believe to be one of the major problems they facepost tane!?

So it's one thing to try and get the liver clean and bile flowing again, this makes sense but what about also addressing parasite infections etc - do we do this simultaneously with cleaning up the liver or do we try to kill off the parasites first??

And once all that's done, what about our gut health? Surely we need to strengthen lining etc to restrict further infections? See how it gets complicated!

Thanks again for your post, there's a couple of supplements you've mentioned that I'm keen to look at!

@TrueJusticeOnce the bile is flowing, that takes care of a lot of nasty bugs in the intestines. Bile alkalizes the GI tract. One cause of SIBO is the bile flow is obstructed. Once the bile is flowing and the accutane is out of the body, I'd imagine the immune system would also greatly strengthen. This would be the step I'd take first: get the tane out of the body and get the liver decongested. This will achieve a lot of results.

Unfortunately, I didn't cleanse and decongest my liver soon enough so my body became LOADED with infections. I'm going to be simultaneously lowering the microbial burden with herbs AND liver & gallbladder flushing while possibly taking TUDCA.

EDIT: Also, I should note that I've done 12 liver flushes and my liver is STILL congested. I can feel intrahepatic gallstones dropping down in my liver area sometimes when eating a fatty meal.
My digestion has GREATLY improved since doing these flushes. I do one every 4 weeks. Incredibly simple.
This is how you do them:
link

EDIT2:
Found a few users who have been helped by UDCA.
Check out the profiles of "and1" and "JosephBuchignani"
Read through their past posts.
and1 post from 2012:
"I know that liver and gallbladder are the root to my complete recovery, this is why I hope to get my hands on UDCA in the coming months. I have tried tons of products and have never been this confident about the potential benefits of a product. It will dissolve cholesterol stones, thereby rejuvenate your liver and gallbladder, it helps your body to detox, reduces inflammation etc. It sounds to good to be true, but it will provide your body simply with the very natural substance it was lacking in order to regain its equilibrium, which is bile. Together with the continued supplementation of artichoke and peppermint supplements, which I cycle, I expect to see the greatest improvement I have experienced in a long long time.

--

EDIT3: another...

Along the TUDCA lines.... its the T in Tudca thats important imo. Totally right about the SIBO. this was my point about parasites, worms, candida , SIBO. etc etc etc. these are just secondary side effects from the root cause. you can treat 100s of these side effects and not cure yourself. fix the underlying issue, and all of these go away.

here is what i believe is the best practice for me right now.

1. copper
2. Taurine
3. Vitamin D/K mag

reasoning... accutane depletes the very things needed to metabolize itself. two of the known substances that get upregulated for this, without a doubt are Copper and Taurine. Without copper, we cantmethylateto produce taurine... without taurine, the bile gets thick and viscous, and we lose the ability to absorb fats and fat soluble vitamins like D and K. We also lose the ability to detoxify thru normal bile excretion. severe Vitamin D deficiency causes massive losses of taurine. so that defines the endless loop for me.

1. Without Copper, retinoids build up in the liver. copper can reverse this is normal people. we arent normal due to bile problems/copper depletion. copper is also needed to produce the cofactor needed to absorb Vitamin D from the sun. I believe this is without a doubt the most important paper for our situation. http://www.ncbi.nlm.nih.gov/pubmed/3679695
Also, if you take copper by itself and mobilize the retinoids, without a way to get rid of it thru the bile, it probably wont do any good, and would cause even more side effects? it will never be just one supplement.

2. This is where Taurine comes into play. Not only does taurine cause the bile to become more fluid, and increases stomach acidity, bile pool size, but it LITERALLYbinds retinoic acid for excretion. Taurine and bile Taurine and retinoic acid conjugation TAURINE and GALLSTONES

3. Vitamin D is needed to reestablish Taurine levels. Vitamin D also upregulates the CYP3A4 enzyme needed for accutane metabolites.

So my theory is this.... Get the stored Retinoid from the liver back into the bloodstream with copper and vigorous exercise. Once in the bloodstream, introduce the cofactors needed to bind it and excrete it, AND replace it in the liver. this would be the Taurine and Vitamin D

http://www.bodyenergyclub.com/aor-taurine-nutritional-amino-acid-supplements.html#.V0B-kpErKUl

Pharmacological properties / Clinical Applications
Taurine is abundantly present in mother's milk, is necessary for normal growth, and present in high concentration in the platelets, lymphocytes, and retina.

(1) Antioxidant. Taurine reacts with hypochlorous acid (HOCI) produced in the retina and certain white cells during the "respiratory burst" to combat infection, thereby protecting the host from oxidative damage. Taurine is also a cell-membrane stabilizer and has been shown to protect against retinol toxicity and lipid peroxidation.

(2) Immunostimulant. Taurine significantly increases lymphocyte viability in a dose-dependent manner. Taurine was also found to be an activator of natural-killer cells and stimulated the release of interleukin (IL-I) from macrophages.

(3) Detoxifying agent. Detoxifying agents render toxic substances more water soluble since, for the most part, such substances are poorly soluble. The increased solubility allows excretion through the kidneys. The amino group of taurine can react with carboxylic acid group of toxins to form amide linkages, e.g. retinoic acid reacts with taurine to form retinotaurine.

RETINOTAURINE http://www.ncbi.nlm.nih.gov/pubmed/7097369 "The low biological activity of this recently identified biliary metabolite suggests that it represents an excretory form of retinoic acid."

A patent by someone using Taurine to reduce 13-cis retinoic acid side effects http://www.google.com/patents/US4545977

so an example would be:

2-3mg copper early am by itself with water.

breakfast 2 grams Taurine
2000iu-6000iu Vitamin D (depending on sun exposure)
1mg K2 mk4
200mg Mag glycinate (also supply extra glycine for bile)

Lunch w/ 1 gram Taurine
Dinner w/ 1gram Taurine

Taurine is sulfur & antagonistic with copper...so its very important to take the copper in the am and eat foods rich in copper as well, so as to avoid deficiency

GET TESTED FOR COPPER AND VITAMIN D LEVELS!!!

@tryingtohelp2014 Thanks for posting the above

Based on JosephBuchignani's post below, I wouldn't say the taurine is the main thing in TUDCA healing accutane victims. Joseph seems to have healed himself with UDCA, not TUDCA.
"UDCA has already fixed my chronic fatigue, now it looks like I'll kiss the cramps goodbye as well. Finally I can eat! Mmm pizza. (Well in 120ish days anyway.)"

On 5/21/2016 at 7:58 AM, yetanotheraccutanevictim said:

this is why liver flushes cure so many people from accutane side effects. I can even feel the congestion in my liver.

This is very interesting. Several months ago I did the Jon Barron cleanse. It involved taking a product called KGP Flush, which is for "temporary relief of kidney and gallstone symptoms". It contains many herbs, here is product page:KGP Flush. I had a very noticeable improvement in my fatigue and mood for the several days that I consumed this tincture. I have another bottle that I will experiment with next week.

On 5/21/2016 at 11:02 PM, SCOTT242 said:

This is very interesting. Several months ago I did the Jon Barron cleanse. It involved taking a product called KGP Flush, which is for "temporary relief of kidney and gallstone symptoms". It contains many herbs, here is product page: KGP Flush . I had a very noticeable improvement in my fatigue and mood for the several days that I consumed this tincture. I have another bottle that I will experiment with next week.

Thanks for sharing! That has a lot of good stuff in it. d-Limonene oil, and the homeopathic remedy, Nux Vomica are excellent for the liver. The other things all seem to focus on dissolving calcifications and increasing urine output. The homeopathic remedy, Nux Vomica, is supposed to be good for a drug overdose. I suggest everyone here go look in their local Wal-Mart for homeopathic remedies. They're cheap. Get one that is for the liver and see how you feel. Comfora 200C can reverse antibiotic damage.
Aethusa 200C cures any sort of dairy intolerance in 80-85% of the population.
Nux Phos 6x or 3x helps for acid reflux/indigestion.

Gold Coin Grass is another excellent herb for the liver. It helps soften gallstones. And of course the classic castor oil packs. Heard great things about them.

introduction to liver congestion
@tryingtohelp2014in this video (on part 3) they talk about glycine, taurine, and phosphatidylcholine to prevent bile from becoming thick and viscous (and thus forming stones). We already knew this. BUT did you know that you can get those ingredients delivered straight to the liver for maximum effectiveness by using a suppository? You may want to try that with the stuff you have on hand. It's easy to make a suppository at home with coconut oil or cocoa butter.

16 hours ago, yetanotheraccutanevictim said:

Great video I just found:

Top 8 Tips For Reversing Accutane Side Effects

short summary I typed up:
The key to getting rid of accutane based side effects is to cure both bile flow issues and successfully remove excess Accutane out of the body. These two things both have to happen before your side effects can be stopped.

Reduce the load of crammed bile caused by cholestasis by supplementing with
bile acids
ox bile
granulated lecithin
chinese bitters

TUDCA on a regular basis to regenerate the cells in the liver and saves the liver from toxicity
Even helps restore bile flow

Eat natural & clean foods to prevent toxicity build-up

Consider using MSM supplement every day
to prevent hardening and calcification
increases passability of nutrients into the cells

coconut oil - absorption occurs without bile or pancreatic enzymes
allows absorption with fat & fat-soluble toxins. Only 3-4 tbsp needed per day

Calcium-D-Glucarate taken 2x per day can prevent accutane reabsorption

Stay away from retinol until bile flow is well taken care of
People react to vit A bc they have too much retinoic acid in their body than they need. More vit A just pushes the accutane into the blood stream leading to a toxic shock.
Consider slowly building up to a liquid form of Vit A which will stil be easily digested by the body. Since there is not enough bile in the intestines, you won't be able to digest fat-soluble vitamins but when in liquid form, it can be easily be digested. Take it little by little until the body gets used to it. This will help replace accutane in the body.

Supplementing with Vit C every night will alkalinize the body and help the body's anti-oxidant capacities.

---

EDIT: this is why liver flushes cure so many people from accutane side effects. I can even feel the congestion in my liver.

I should also add that Chelidonium majus seems to be powerful for stimulating bile
--

Also a testimionial from a forum user:
and1:
"

and1

Hey, I used to post here and bile flow is also the one thing or the most important thing to get going in order to get healthy. I could write a couple of pages why it is so important, you probably already know. From my understanding the most underappreciated function that bile flow brings online is the elimination of heavy metals. For instance mercury elimination is largely achieved via the bile and you may know how disruptive this mercury is to our system.

What helps to promote bile flow and unplug the bile ducts?

Heavy hitters:

- UDCA, take at your own risk, I have experimented with it and it helped a lot, I posted about it on this forum, so...

- liver flushing, it is in the same league as UDCA as far as my experience goes, but it takes a lot more effort and preparation than swallowing a pill, however in my judgement you have less downside risks

- exercise like jump-roping, rowing, anything that stimulated you gallbladder

All-Stars - They may work best in combination, you have to experiment a little, some may take a few weeks (4-8) until you notice that the color of your feces is gradually normalizing etc. and in consequence you get better, symptoms gradually disappear:

- Silymarin

- TMG/Betain

- NAC

- Taurine

- Liv52

I head very good experiences with TMG, Silymarin and Liv52. I overdosed Liv52. Looked at how bodybuilders like to dose this stuff and than dosed accordingly. Lately I have had great success with NAC, it raises glutathion. I would cycle 1200 to 1800 mg taken throughout the day, highly diluted in water, for 2 to 3 months at a time and than get off for a few months.

I'd recommend against taking anything for longer than 3 months at a time and would advice cycling the supplements.

Breaking the enterohepatic cycle is also very critical, I am still working on this part once your bile flow is back online. Hope this helps."

Thanks for posting! I'd be very interested to know the background to this. This sounds almost like the outcome of a study specifically on the persistent side effects of accutane, and sounds like it's had input from people with a professional medical understanding, as oppose to someone who's read some pubmed studies and some articles online, like most of us on these forums.

I've cycled TUDCA a couple of times, and I definitely felt better for it - one thing I noticed was I started to sweat again, which is something that tane pretty much stopped. I.e I'll never get underarm sweat patches, even on a hot day, whereas taking TUDCA made me start again. The reason I stopped it though was I started getting pains in my liver. I'll probably restart after watching that though, and I've got some different brands to try as well now.

Also worth noting TUDCA was pretty much the basis of Mario Vitali's recovery (from Finasteride sides, but the same old symptoms obviously) http://forums.phoenixrising.me/index.php?threads/unfolded-protein-response-and-a-possible-treatment-for-cfs.37244/

25 minutes ago, tanedout said:

Thanks for posting! I'd be very interested to know the background to this. This sounds almost like the outcome of a study specifically on the persistent side effects of accutane, and sounds like it's had input from people with a professional medical understanding, as oppose to someone who's read some pubmed studies and some articles online, like most of us on these forums.

I've cycled TUDCA a couple of times, and I definitely felt better for it - one thing I noticed was I started to sweat again, which is something that tane pretty much stopped. I.e I'll never get underarm sweat patches, even on a hot day, whereas taking TUDCA made me start again. The reason I stopped it though was I started getting pains in my liver. I'll probably restart after watching that though, and I've got some different brands to try as well now.

Also worth noting TUDCA was pretty much the basis of Mario Vitali's recovery (from Finasteride sides, but the same old symptoms obviously) http://forums.phoenixrising.me/index.php?threads/unfolded-protein-response-and-a-possible-treatment-for-cfs.37244/

Same here; I'd love to know who did the research behind that video's content.

Thanks for sharing your TUDCA experience. Your liver was probably having pain because stuff was moving through and out of it. I get liver pain a couple days after doing liver flushes sometimes.

If anyone else here has experience with using it, do share. Share dosages and timelines as well if possible.
Also, please share brands. We need to find the purest most effective source.

On 5/22/2016 at 3:04 AM, yetanotheraccutanevictim said:

Same here; I'd love to know who did the research behind that video's content.

Thanks for sharing your TUDCA experience. Your liver was probably having pain because stuff was moving through and out of it. I get liver pain a couple days after doing liver flushes sometimes.

when looking at improving bile salt composition,a dose of around 15-20 mg/kg bodyweightTUDCA seems best.
1,750 mg per day is the highest you'd ever want to go based off a study they did on fatty liver disease.
My safe dose would be around 1,100 mg daily.
Based off the opinions of anabolic steroid users, they say 200-500 mg per day is plenty to prevent liver damage.

If anyone else here has experience with using it, do share. Share dosages and timelines as well if possible.
Also, please share brands. We need to find the purest most effective source.

If I remember correctly Joseph Buchignani who was a member on here and contributed to this thread took TDUCA! I believe he posted what helped him. Though I can't say it would help others 100% ( what he did outside of TUDCA)!

You can look on previous pages and on this website for his story and advice especially on TUDCA.

[Edited link out]

This is a long story, and one where I literally don't know what to do. But I feel it's relevant on this topic

So here goes.

So about 2 years ago I started taking Accutane(Roaccutane) I had exhausted all options had tried numerous face washes, benzoyl peroxide antibiotics and even Lazers. I eventually had enough and started investigating measures to permanently reduce/destroy my acne. My skin was incredibly oily and has hundreds of little bumps all over my face that would become inflamed.
I started investigating success stories on the Internet and came across Roaccutane. I continued to research this and went through the pros and cons extensively. I knew that if I went to a doctor or dermatologist it would not be prescribed and would be back at square 1.
So I took the plunge and ordered some Roaccutane online at a relatively low dose of of just 5mg.
It initially started well it took time and I had read about the initial breakout which I had ,and flushed all my spots out so I knew it was working.
I can't remember why but I eventually decided to up the dose to 20mg daily( maybe for better results.
All while doing this only washing with water to avoid irritation and then using a moisturiser.
This worked amazingly and gave me the clear complexion I had longed for and finally my life back.
I had originally planned to do this for a 6 month course and I did as I planned and stopped the course.
I remember it quite clearly it was a week after I stopped and was out with friends I touched my face and felt a huge spot on the side of my face, I was mortified and didn't want to go through acne again, so immediately restarted taking 20mg again and proceeded to have the best year of my life.
Socialising regularly eating what ever I like established a good job and more importantly not worrying about my skin and just generally having a life.
I knew that I should of stopped at some point but didn't want to risk the acne coming back.
Some time in 2015 I picked up a case of Molluscum contagiosum which I had diagnosed from a derm but I'm not sure if that is connected to what I'm about to tell you.
In November whilst continuing my 20mg daily regime I looked in the mirror and saw a array of small bumps on my face this continued for a week and I was totally confused why this had happened
And I didn't know what to do.
So I did a bit of research and decided to up my dose to 40mg
And then to 80mg which cleared my acne perfectly over Christmas.
After Christmas I moved in with my Girlfriend my face exploded it was like a rash across my forehead and spots all over my face aswell it came after a hot bath and a visit to the gym.flaky dry skin all over my face. This happened twice and was almost like a allergic reaction, I had never had this before.
I have literally become a recluse didn't want to go out and didn't want my girlfriend seeing me I pretty much think my life is over.
My skin was at its worse it had ever been in some time I decided to stop the accutane and use a exfoliator on my face to get rid of some of the dead skin this worked ok and cleared up some of the acne/blocked pores on the lower half of my face with the problem being on my my forehead.
So I have rash like load of spots present on my forehead with flaky dry skin and a slight itch particular on the right side of my hairline, I can feel the oil coming back already on the bridge of my nose.
I went to the GP and had a blood test and everything was normal and he told me talk to someone and said I had to sort my own derm visit out myself if that's what I wanted.
I don't know why but I've started taking 5mg a day again to try and cure this and get my life back but I think this is making it worse.

I don't know what to do and am having horrible thoughts as i see no way out of this nightmare.

Do I have hypervitamintosis ( to much vitamin a in my body) from taking accutane for so long.

I know I've got myself into this mess but I'm at a loss as to what to do?

Sent from my iPhone

On 5/25/2013 at 9:50 PM, JosephBuchignani said:

I'm still doing reasonably well. Current foci are going to bed earlier, controlling overeating, and increasing / being regular with UDCA dosage. Later I will try to comprehensively hack my apparent absence of bile / pancreatic production.

On 5/27/2013 at 5:51 PM, JosephBuchignani said:

Major breakthrough. Doubled dose of UDCA to something ridiculous like 2g per day. Massive improvement. Definitely had cholestasis. Detox and digestive systems were not working, no matter how perfect the regimine, still life was difficult. Now is easy.

More UDCA/TUDCA encouragement!

Listen to the first few minutes of this interview to see how poor bile flow screws up everything.

EDIT
Wow.. did anyone know SAMe helps with cholestasis (bile duct congestion)!?
https://www.ncbi.nlm.nih.gov/pubmed/2081476

Could someone here please purchase Seeking Health SAMe and Glytamins suppositories and TUDCA and see how you do after a couple weeks? I am short on cash at the moment. If I had $, I would be doing this asap.
Again, please share TUDCA brands we should try.

Someone should study this patent: (Glytamins suppository)
https://www.google.com/patents/US20070264360

Also, this is a patent that Tryingtohelp2014 shared a while back on how to rid the body of retinoid toxicity:
https://www.google.com/patents/US4649040

EDIT2:
Has anyone ever tried Klinghardt's liver compression technique?
http://www.sophiahi.com/videos/

[Edited link out]

"As a major carrier of toxins from the body, proper bile flow is a critical final step in the metabolic detoxification process. Impairment of bile flow (cholestasis), resulting from dysfunction within the liver or blockage of the bile duct, can result in the buildup of liver toxins and liver injury. Cholestasis can also be the result of the detoxification process itself; there is increasing evidence that the detoxification and excretion of clinical drugs into the bile can produce cholestatic liver disease.

Artichoke has been used for centuries in folk medicine as a liver protectant and to stimulate bile flow (choleresis), and is the best-studied herbal choleretic agent.

Artichoke contains several antioxidants that can protect against oxidative liver damage, as well as caffeoylquinic acids, which have been shown to stimulate bile flow in animal models.

Caffeoylquinic acids may also be responsible for the choleretic properities of yarrow, fennel, and dandelion."

EDIT:
Person who restored bile flow with liver flushes:
http://www.curezone.org/forums/fm.asp?i=1983501#i

Where are all the people who were saying Liver flushes were a waste of time 12 to 16 months ago??

Well done on setting people back - I knew it, it was the one thing that cured people and isn't that hard to do. I'm now at number 4 which I'll start next week. Even the lady who runs the colon hydrotherapy clinic I go to said to me she didn't get a real rush of energy till cleanse #7 and she hasn't touched accutane, so there's hope for all of us. Remember thoughto do it by the book i.e colon flushes before and after the actual liver cleanse.

Its time to get those livers/gallbladders clean as can be!!

Best of luck.

I got blood tests done but vitamin D wasn't on it.Sorry for the miscommunication

Sunlight in warm weather continues to help my situation.30-45 mins. Building toward 1 hour a day, eventual exercise out there as joints reach a certain level of improvement.Hopefully this can do as much for others as it has for me.

Having a tough time finding UDCA online? For those that have, could you point me in the right direction. Seems like TUDCA will be easier to get ahold of, but I'm worried it won't be as effective.

On 5/23/2016 at 4:00 AM, yetanotheraccutanevictim said:

More UDCA/TUDCA encouragement!

Listen to the first few minutes of this interview to see how poor bile flow screws up everything.

EDIT
Wow.. did anyone know SAMe helps with cholestasis (bile duct congestion)!?
https://www.ncbi.nlm.nih.gov/pubmed/2081476

Could someone here please purchase Seeking Health SAMe and Glytamins suppositories and TUDCA and see how you do after a couple weeks? I am short on cash at the moment. If I had $, I would be doing this asap.
Again, please share TUDCA brands we should try.

Someone should study this patent: (Glytamins suppository)
https://www.google.com/patents/US20070264360

Also, this is a patent that Tryingtohelp2014 shared a while back on how to rid the body of retinoid toxicity:
https://www.google.com/patents/US4649040

EDIT2:
Has anyone ever tried Klinghardt's liver compression technique?
http://www.sophiahi.com/videos/

More info from:
[Edited link out]

"As a major carrier of toxins from the body, proper bile flow is a critical final step in the metabolic detoxification process. Impairment of bile flow (cholestasis), resulting from dysfunction within the liver or blockage of the bile duct, can result in the buildup of liver toxins and liver injury. Cholestasis can also be the result of the detoxification process itself; there is increasing evidence that the detoxification and excretion of clinical drugs into the bile can produce cholestatic liver disease.

Artichoke has been used for centuries in folk medicine as a liver protectant and to stimulate bile flow (choleresis), and is the best-studied herbal choleretic agent.

Artichoke contains several antioxidants that can protect against oxidative liver damage, as well as caffeoylquinic acids, which have been shown to stimulate bile flow in animal models.

Caffeoylquinic acids may also be responsible for the choleretic properities of yarrow, fennel, and dandelion."

EDIT:
Person who restored bile flow with liver flushes:
http://www.curezone.org/forums/fm.asp?i=1983501#i

Ive written extensively on this forum about SAM-E Taurine is the end metabolite from SAM-E that will help us.

Ive tried the Glytamins. they are Glycine based. Glycine doesnt bond with retinoic acid. We need a Taurine based product. Taurine specifically binds with retinoic acid

In that Patent, methionine was the main rescuing agent cited. again, Taurine is an end metabolite of methionine that will help us.

Just need to take a bunch of it 3x a day.

http://www.holistichelp.net/blog/what-are-oxalates-and-how-can-they-affect-your-health/

1. Too much fat in the diet can contribute to elevated levels of oxalate, if the individual is not absorbing fatty acids properly, such is the case if there is a bile salt deficiency. Fatty acids that arent absorbed inhibit calciums ability to bind with oxalates, which is needed to move them out through the stool. Bile salt may be deficient for a variety of reasons, including taurine insufficiency, SIBO, reduced function of liver or gallbladder, antibiotics, insufficient gut bacteria, some pharmaceutical medications, low pH, and genetic impairments. Additionally, oxalates oxidize your fats, making them rancid.

On 5/23/2016 at 8:39 AM, TrueJustice said:

Even the lady who runs the colon hydrotherapy clinic I go to said to me she didn't get a real rush of energy till cleanse #7 and she hasn't touched accutane, so there's hope for all of us. Remember thoughto do it by the book i.e colon flushes before and after the actual liver cleanse.
Its time to get those livers/gallbladders clean as can be!!

2

Hear hear! Yeah, I also didn't get ANY results until flush #4. Every flush after that produced results! I'm on flush #12. I'm on a completely different level of health compared to before flushing. I suggest doing them every 3 weeks for best results. Also, I use 6-8 oz of olive oil per flush instead of 4 oz. Lemon juice is my preferred citrus juice.

On 5/23/2016 at 4:46 PM, QuietSoldier said:

Having a tough time finding UDCA online? For those that have, could you point me in the right direction. Seems like TUDCA will be easier to get ahold of, but I'm worried it won't be as effective.

UDCA is a prescription. From what I've read, it looks like TUDCA is exactly the same with a taurine molecule attached (which we need to conjugateretinoic acid out of our bodies).

Here are two brands I'm looking at that seem to be the lowest in excipients & fillers compared to other brands:

I wish good companies like Thorne Research, Pure Encapsulations, Seeking Health, Designs For Health, etc.. carried TUDCA. Someone share what you find. There was one brand people were sharing on this forum a couple months ago. Can't find it.

On 5/23/2016 at 8:41 PM, tryingtohelp2014 said:

Ive written extensively on this forum about SAM-E Taurine is the end metabolite from SAM-E that will help us.

Ive tried the Glytamins. they are Glycine based. Glycine doesnt bond with retinoic acid. We need a Taurine based product. Taurine specifically binds with retinoic acid

In that Patent, methionine was the main rescuing agent cited. again, Taurine is an end metabolite of methionine that will help us.

Just need to take a bunch of it 3x a day.

4

Glytamins didn't make any difference? Perhaps you are too clogged up with stones.
I'd say we are still in great need of glycine as accutane upregulates GNMT and causes glycine deficiency.
https://www.ncbi.nlm.nih.gov/pubmed/12054489
http://jn.nutrition.org/content/133/12/4090.long
The glycine will also help thin out the bile to get it moving again. I think that's the main thing we are looking to accomplish. That's why TUDCA is so important.

Are you ever going to do liver flushes? I don't think we can be cured without them. I had so much crap clogged up in my biliary system. I don't think anything could get that out biochemically. The thick cholesterol stones must be forcefully pushed out with a gigantic squeeze of bile.

--
How is everyone's digestion?
Anyone here have floating stools?
Stool white, gray, tan, or green in color?
Food seems to sit in the stomach?
Reflux?
Indicative of not enough bile entering the intestine.

Who here has ever had back pain near their right shoulder blade? That is gallbladder or liver congestion.
Eat 2 large avocados on an empty stomach in the morning and see what happens (post results).

Note:
We should all be ingesting bone broth on a daily basis.
[Edited link out] (excellent product) - has glycine. Listen to the podcast.

EDIT: lol, if this person doesn't have MAJOR problems later, it'd be a miracle.
http://www.acne.org/messageboard/topic/359370-what-im-doing-for-my-acne-right-nowmy-experience-with-accutane-and-bcp/#comment-3524925

Hi Guys,

I would like to do something about my hairloss and my hairthinning after my Accutane course because I really miss the way my hair used to be. I went to the drugstore and got 'Minoxidil' and a vitamin supplement to stop hairloss.
Has anyone experience with Minoxidil against hairloss?
One "positive thing" that Accutane taught me is that I won't take drugs anymore before really knowing what damage it can cause. The vitamin supplement is with Vitamin B3, B6, B8 and zinc.. So I don't think that can really do harm, but I'm more afraid of the 'Minoxidil' because it seems kinda serious. The last thing I want is regretting taking another drug...

Thanks!

9 hours ago, HideAndSeek said:

Hi Guys,

I would like to do something about my hairloss and my hairthinning after my Accutane course because I really miss the way my hair used to be. I went to the drugstore and got 'Minoxidil' and a vitamin supplement to stop hairloss.
Has anyone experience with Minoxidil against hairloss?
One "positive thing" that Accutane taught me is that I won't take drugs anymore before really knowing what damage it can cause. The vitamin supplement is with Vitamin B3, B6, B8 and zinc.. So I don't think that can really do harm, but I'm more afraid of the 'Minoxidil' because it seems kinda serious. The last thing I want is regretting taking another drug...

Thanks!

Liver flushes dude - get your liver/gallbladder clean.

I wouldn't go taking any other powerful drugs - it's gonna fuck your liver up even more!!

I have thinning damaged hair, prob a result from just how much the tane dried out my entire body all those years ago - I'm gonna clean up the liver and after that work on somehow bringing more moisture back into the body!!

I think I did about 6 liver flushes 2 years ago and didn't notice any dramatic changes

I then found a bunch of information backed up with studies about how they don't really work to get rid of gallstones

so im on the fence about them at the moment. I will probably do another 5 or so just to say I've done a sufficient number