32 minutes ago, hatetane said:

So, I know this is nothing new but given that there are several doctors that I know of who treat accutane ED with cortisol. Dr Irwin Goldstein and
Dr Alan Jacobs - Has anyone had this treatment and if not why isn't it an option for you?

I also know it is the choice treatment given to young men with low testoterone.

• Mental and psychological ailments such as depression
• Faintness and dizziness
• Weakness and fatigue
• Heart palpitations
• Emotional hypersensitivity
• Inability to cope with stress
• Social anxiety
• Muscle weakness
• Headache, scalp ache, or general body ache
• Severe or dull lower back pain
• Extremely sensitive skin
• Nausea, diarrhea, and vomiting
• Abdominal pain and hunger pain despite an empty stomach
• Extreme craving for salty foods
• Anxiety and jitters
• Clumsiness and confusion
• Motion sickness
• Insomnia and dark circles under the eyes
• Low bladder capacity and symptoms of IBS
• Irregular or non-existent menstrual period

I know this has probably been discussed at length but as it seems like it is the only treatment likely on offer would like an up-to-date
perspective on this.

actually nasonex has helped with alot of this stuff i could put a checkmark next too. a steroid is a funny thing though it can make you feel happy, sad, angry.
i need to almost start keeping a journal or something of positive/negatives of all this stuff i tried. because i forget. and then im like oh yea thats why i stopped taking that. the problem is i have some bad effects from something or crash and i get worried something is doing more harm then good so i quit it.

^ the key here is that nasonex contains cortisol. i made the correlation with both guitarmans experience using nasonex and the feeling post tane and finasteride users get after a night of copious alcohol consumption, the increase in cortisol levels. mental clarity lifted. anxiety dissipates. erections full on. As well as the scientific papers discussing 13-cis-ra potentialatrophy of the pituitary and hypothalamus gland. these glands are largely responsible for homeostasis. and theyalsoplay a large rolein the digestive system too. everything really.

13 minutes ago, guitarman01 said:

actually nasonex has helped with alot of this stuff i could put a checkmark next too. a steroid is a funny thing though it can make you feel happy, sad, angry.
i need to almost start keeping a journal or something of positive/negatives of all this stuff i tried. because i forget. and then im like oh yea thats why i stopped taking that. the problem is i have some bad effects from something or crash and i get worried something is doing more harm then good so i quit it.

Thanks Guitarman - I will check nasonex out now. So you got experience of clomid and cortisol? Sorry I know this is probably old news for you but an update for all the newbies wi be really helpful. I know a 20 year old boy just been offered cortisol treatment - is this good or bad? T levels very low?

18 minutes ago, hatetane said:

31 minutes ago, guitarman01 said:

actually nasonex has helped with alot of this stuff i could put a checkmark next too. a steroid is a funny thing though it can make you feel happy, sad, angry.
i need to almost start keeping a journal or something of positive/negatives of all this stuff i tried. because i forget. and then im like oh yea thats why i stopped taking that. the problem is i have some bad effects from something or crash and i get worried something is doing more harm then good so i quit it.

Thanks Guitarman - I will check nasonex out now. So you got experience of clomid and cortisol? Sorry I know this is probably old news for you but an update for all the newbies wi be really helpful. I know a 20 year old boy just been offered cortisol treatment - is this good or bad? T levels very low?

no sry have only tried nasal steroids. my allergist told me nasonex is the strongest best. i have to agree its had more positive, profound effects on me then flonase, nasocort, or rhinocort, though these are otc in the us and easier to get.nasonex is the only one that i believe has had a effect on any ed type symptoms. i believe they are all alittle different but spose to have the same effect when it comes to allergies. my t levels were normal dhea was normal as well i believe.

1 hour ago, tryingtohelp2014 said:

lol go thru my posts.... i posted as hard for manganese and longer( a year ago) as i am for copper now . they are related. and they are also antagonistic. manganese is a cofactor for one of the two ways accutane is metabolized thru glucurondiantion. its calledUDP-glucuronosyltransferase 2B7. I used it for a long time for possible tendons and ligament connections. i still think it will be valuable. helped a bit with some inflammation symptoms. not the cure though.

MANGANESE (Mn) Manganese is called the "maternal mineral" because manganese deficiency in females causes a reduced maternal caring for her young. Mn is necessary for the production of manganese superoxide dismutase, one of the key antioxidants in the body. Enzymes involved in cholesterol synthesis are manganese dependent, so a manganese deficiency can decrease sex drive. Mn is required for normal thyroid and adrenal gland activity. Manganese seems to work with iron and is therefore necessary for proper iron metabolism. Excessive iron or copper supplementation can decrease manganese and excessive manganese can deplete iron and copper. Therefore it is important to supplement manganese (and it's partner chromium) when supplementing iron and copper.

like your link stated, its a"byproduct of themitochondrial electron transport chain" the actual electron transport chain comes first.

could you find out the exact levels in your ceruloplasim test after a week of supplementation?

A possible explanation is it could get worse before it gets better... the dryness could be a symptom of something being mobilized from the liver. that whole inverse copper/vitamin A relationship. it actually could be a good sign.

also for the sake of trying everything here when it comes to vitamins and minerals. so no one else needs to waste their time and money
what hasnt been tried? excluding copper atm.and i dont mean some small benefit but big picture. and it might not be a nutrient problem in the first place, but i want to move on from this so people know. i could maybe only still put a question mark next to selenium? its about the only one i havent trialed for a period of time. also assuming vitamin a is still in the body, then yea copper makes sense. but if not what else?

vit a
vit c
vit d
vit e
vit k
thiamin
riboflavin
niacin
b6
folic acid
b12
biotin
pantothenic acid
calcium
phosphorus
iodine
magnesium
zinc
selenium
copper
manganese
chromium
molybdenum
chloride
potassium

4 minutes ago, guitarman01 said:

also for the sake of trying everything here when it comes to vitamins and minerals. so no one else needs to waste their time and money
what hasnt been tried? excluding copper atm.and i dont mean some small benefit but big picture. and it might not be a nutrient problem in the first place, but i want to move on from this so people know. i could maybe only still put a question mark next to selenium? its about the only one i havent trialed for a period of time. also assuming vitamin a is still in the body, then yea copper makes sense. but if not what else?

vit a blood test years ago normal
vit c
vit d blood test normal
vit e blood test normal
vit k
thiamin
riboflavin
niacin
b6
folic acid blood test normal
b12 blood test normal
biotin
pantothenic acid
calcium blood test normal
phosphorus
iodine
magnesium was rbc tested normal
zinc
selenium
copper blood test normal
manganese
chromium
molybdenum
chloride
potassium

il give my quick thoughts on each one

also testosterone free 23 value range 9-30ng/dl
testosterone 738 range 240-950 ng/dl
dhea 5.9 range <13ng/ml

every single lab im looking at is pretty much perfect so far.

http://www.lifeextension.com/magazine/2006/5/report_blood/page-01

The 10 Most Important Blood Tests

On 3/3/2016 at 5:24 PM, Modeaa said:

maybe by killing some pathogens(by taking antibioic,copper, etc)

have you been taking copper btw? what is your opinion on this at the moment? has anyone else been taking copper ?

7 hours ago, macleod said:

Growth Hormone

sylvester stallone swears by this. im not kidding. and look at him. hes jacked and still has a full head of hair and hes old as hell.
http://www.today.com/id/22728530/ns/today-entertainment/t/sylvester-stallone-discusses-hgh-charge/#.Vts97vkrJmM
Although associated with sports, HGH is said to be very popular in Hollywood among stars trying to stave off the effects of age. Doctors in anti-aging clinics also prescribe it because of its reported ability to add thickness and elasticity to skin, improve vision, and make it easier to recover after physical exercise

yea, a lot of people swear by it. and that's all good to note or whatever. but this is the protocol when dealing with glandular issues such as the thyroid. you balance the hormone levels and add GH on the side which assists in the repair process seemingly on a dna transcription level. it may be our best shot at getting the glands to respond again back to life.

For those who are always speaking in a pessimistic way, even for those who are 10 years post accutane side effetcs. Please stop. Because it is always hard to read, especially for the new comers who took this drug recently and havent realized yet what is going on: if they came to this thread and read at first that there is no hope blablabla, that we're all screwed etc , imagine how hopeless they'll be , whereas there is actually hope.

there is enough recovery stories and science evidence to attest that we can get cured.

Personally I think that accutane will eventually be a bless once I'll recover.
It made me interested in so many things.I learned things I never would have learned without Roaccutane.
What does not kill you make you stronger. Sooner or later

and once again, our body do have the ability to heal by itself. Do not waste Time trying to cure symptoms .

3 minutes ago, macleod said:

yea, a lot of people swear by it. and that's all good to note or whatever. but this is the protocol when dealing with glandular issues such as the thyroid. you balance the hormone levels and add GH on the side which assists in the repair process seemingly on a dna transcription level. it may be our best shot at getting the glands to respond again back to life.

Has a doctor suggesteted Clomid or cortisol to you?

5 hours ago, tryingtohelp2014 said:

lol go thru my posts.... i posted as hard for manganese and longer

how high a dose of manganese did you take for how long?
like you said antagonist. copper made my left eye twitch worse that ive had for awhile now.
just a quick google and 2 different forums are saying manganese deficiency.
calcium supplement caused my eye twitch in the first place. another manganese antagonist or interferes with absorption. so just wondering.

2 hours ago, guitarman01 said:

how high a dose of manganese did you take for how long?
like you said antagonist. copper made my left eye twitch worse that ive had for awhile now.
just a quick google and 2 different forums are saying manganese deficiency.
calcium supplement caused my eye twitch in the first place. another manganese antagonist or interferes with absorption. so just wondering.

and youre taking way too much.  bad things happen when you take way too much of anything.

8mg per day of copper= only 12% absorbed (but stops other things, and throw off other nutrients)

1.5mg per dose = 56% absorption rate

if youre going to overdose on anything... go get drunk on hard liquor and see if you feel better. more than one anecdote says people feel much better after drinking... would also suggest a retinoic acid backup.

Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P4502E1.

http://www.ncbi.nlm.nih.gov/pubmed/11208727

P4502E1 is an Iron based cytochrome btw

Effects of acute overdose of vitamin A on the hepatic content of K, Na, Mg, Fe, Cu and Zn, in rats.  http://www.ncbi.nlm.nih.gov/pubmed/8883741 While Na and Zn increased, the other cations decreased its concentrations in the whole liver. 

2 hours ago, tryingtohelp2014 said:

and youre taking way too much.  bad things happen when you take way too much of anything.

8mg per day of copper= only 12% absorbed (but stops other things, and throw off other nutrients)

1.5mg per dose = 56% absorption rate

if youre going to overdose on anything... go get drunk on hard liquor and see if you feel better. more than one anecdote says people feel much better after drinking... would also suggest a retinoic acid backup.

Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P4502E1.

http://www.ncbi.nlm.nih.gov/pubmed/11208727

P4502E1 is an Iron based cytochrome btw

 

 

Effects of acute overdose of vitamin A on the hepatic content of K, Na, Mg, Fe, Cu and Zn, in rats.  http://www.ncbi.nlm.nih.gov/pubmed/8883741 While Na and Zn increased, the other cations decreased its concentrations in the whole liver. 

 

 

(faceplants head on palm).uh thanks for the response but at no point did you ever answer my question , but i already knew this was the kind of answer i was going to get. you've done this twice now lol.  if it came down to drinking my retinol stores would be -1000. i dont want to have to browse all your posts to get the answer and i see you knew about vitamin b2 as well. communication is key. if it was me id be like yea i took this much manganese for this long but i dont think that was it. instead you just go right back into copper lol. i didnt OD on copper the upper limit is 10mgs for a reason, i was just asking how much manganese you took for how long. I can see why people get a little frustrated . it seems like ive basically been trailing everything you have studied so just tell people some things to save the time and effort, damn. and what happens when copper is or isnt it?  we still need to keep an open mind to everything to solve this shit . no tunnel vision. 

I got my my plan, nutritional balancing. M0fo, sarahvictoria, and a few others have all testified to feeling mostly better. Interesting how a few of them are not posting anymore, probably living an easy, hassle free life.

Im done with this thread for awhile. Will create a reminder on my phone to check my pm's and where I left off on this thread in about 6 months.

Plan an is nutritional balancing, complete program with saunas, enemas etc. I don't know if the idea is to get copper out, or copper in. It's all wack. The supplement program that propecia guy went on to improve his micro biome a few pages back is in sync with NB.

7 hours ago, guitarman01 said:

also for the sake of trying everything here when it comes to vitamins and minerals. so no one else needs to waste their time and money
what hasnt been tried? excluding copper atm.and i dont mean some small benefit but big picture. and it might not be a nutrient problem in the first place, but i want to move on from this so people know. i could maybe only still put a question mark next to selenium? its about the only one i havent trialed for a period of time. also assuming vitamin a is still in the body, then yea copper makes sense. but if not what else?

vit a
vit c
vit d
vit e
vit k
thiamin
riboflavin
niacin
b6
folic acid
b12
biotin
pantothenic acid
calcium
phosphorus
iodine
magnesium
zinc
selenium
copper
manganese
chromium
molybdenum
chloride
potassium il give my quick thoughts on each one

Glutathione ,vit C, vit E and Selenium together might be worth a try. (see previous article)
You say rule these out - not sure that you can actually say that, just because you tried them without success. For many reasons: duration, dosage, combinations. Also, some may have slowed damage down or even halted it but you may not have noticed this. Some people for sure have seen improvements with some of these - depends on individual ailments. I agree that maybe none offer a magic formula for one pill fits all - but in terms of health benefits, some of these could and probably are helpful. In general I agree that something much more radical is needed but I do believe many many baby steps is definitely the way to go for now.

Guys, how bad and how long are your hangovers from a night of drinking??

Mine for example have gone from only a few hours after i wake up too having a buzzed hangover where i struggle to sleep for 3 days after

Copper study. no changes after 10mgs for 12 weeks.
http://m.ajcn.nutrition.org/content/42/4/681.abstract

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099351/#!po=58.6957
You guys should read this about sibo. This can also cause fat and protein malabsorption

Also read this
http://www.psoriasisdietplan.com/2015/04/probiotics-are-useless-saccharomyces-boulardii-as-sibo-cure/
I think align just caught up with me tonight. This article could be right. You don't fight bacteria with more bacteria. I felt like absolute shit tonight after taking align. My head was on fire

Are there any good benefits if you drink just one glass of wine per day? Or do you have to get schnockered to feel normal for a bit?

3 hours ago, Justmom said:

Are there any good benefits if you drink just one glass of wine per day? Or do you have to get schnockered to feel normal for a bit?

Yes, I am looking into Isotretinoin's role in attenuating (reduce the force of) Nitric Oxide production in the body. Reservatrol, which is in red wine, is a huge NO booster which is crucial for endolitheal function.

The "benefits" of drinking a huge amount of alcohol that us post tane/finasteride users have is thought to be either the cortisol (steroid hormone) increase or byinducing allopregnanolone synthesis. We're not sure which. But, of course, the negatives of alcohol in large amounts outweigh the temporary "gains" that we see. And they are very short lived. So, yes to a glass of wine or two a day. Big no to binge drinking.

I have a few theories backed by scientific research that I will be posting on here soon, but I believe I am really close to, at the very least, coming up with a band-aid for the damage 13-cis-ra has caused. And the general specifics are 1. hormone balancing 2. glandular repair 3. diet and exercise

In the mean time, follow a healthy diet, exercise, and include some of these listed supplements:

http://www.anabolicmen.com/boost-nitric-oxide-naturally/

http://www.thehealthyhomeeconomist.com/say-no-to-accutane/

12 hours ago, guitarman01 said:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099351/#!po=58.6957
You guys should read this about sibo. This can also cause fat and protein malabsorption

Also read this
http://www.psoriasisdietplan.com/2015/04/probiotics-are-useless-saccharomyces-boulardii-as-sibo-cure/
I think align just caught up with me tonight. This article could be right. You don't fight bacteria with more bacteria. I felt like absolute shit tonight after taking align. My head was on fire

You should definitely get tested for SIBO before going on probitocs. Taking probitocs while having SIBO is like adding gasoline to a fire. I remember my symptoms where really bad sinus pressure/headaches when taking probitocs while I had SIBO.

I had that phenomenon again where I gained mental clarity after drinking. I had about 4 drinks (first time drinking since last Aug) a couple nights ago. I wasn't completely clear headed like I've experienced before but I did feel alot better. Only lasted for about 2-3 hours before the hangover kicked in.

39 minutes ago, Bobby.Digital said:

You should definitely get tested for SIBO before going on probitocs. Taking probitocs while having SIBO is like adding gasoline to a fire. I remember my symptoms where really bad sinus pressure/headaches when taking probitocs while I had SIBO.

I had that phenomenon again where I gained mental clarity after drinking. I had about 4 drinks (first time drinking since last Aug) a couple nights ago. I wasn't completely clear headed like I've experienced before but I did feel alot better. Only lasted for about 2-3 hours before the hangover kicked in.

yea i might make an appointment with a gastro dr soon to get tested for sibo. i think i could make the connection too between gut health and how my face, head sinuses, and even ear fullness is effected. there are alot of supplements in the past that seem to effect my ear fullness that leads to the heavy head and brain fog feeling. this tells me some symptoms are coming from the gut. but if it reaches all the way to my ears and sinuses, this is almost some kind of acid reflux then. or causing some inflammatory trigger reaction that inflames my sinuses and ears or has them create more mucus?
im going to try florastor for the moment, it works differently in that it is a yeast. im also going to get tested for sibo. if I have this, this would make the 3rd or 4th person that i know of to be diagnosed with this on this forum.

Using probiotics or garlic when you have SIBO.Ive written previously about the digestively miserable condition calledhttp://health.usnews.com/health-news/blogs/eat-run/2014/03/25/sibo-a-four-letter-word-for-bloatin g">Small Intestinal Bacterial Overgrowth,in which normal colonic-type bacteria take up residenceen massefurther upstream in the small intestine. A common misconception is that SIBO involves overgrowth of bad or disease causing bacteria, and this misconception leads many patients to believe they should start supplementing themselves with a variety ofhttp://health.usnews.com/health-products/top-rec-probiotic-dietary-supplements-10 9">probiotics, or good bacteria to help fight the bad bacteria and restore balance to the gut ecosystem.

In reality, theres nothing inherently "bad" about the bacteria in SIBO other than that theyre colonizing the wrong neighborhood; rather, SIBO is typically caused by good bacteria living in an inappropriate location. So by pouring billions of extra colony-forming units of would-be neighbors into a small bowel thats proven itself so hospitable to overgrowing them, youre literally replenishing the population youre trying to eradicate. Taking a (bacterial) probiotic when you have SIBO or frankly, even when you have a past history of SIBO is therefore likely to be more hurtful than helpful. If and when your doctor prescribes an antibiotic to treat your SIBO, a yeast-based probiotic likeSaccharomyces boulardii(commonly marketed as Florastor) can be helpful to prevent antibiotic associated diarrhea and maintain some semblance of balance in the gut without contributing to the risk of bacterial overgrowth.

The things that I am 99% sure have worked at helping symptoms are:

All for now forum    

1 hour ago, Fchawk said:

I still think having sufficient quantities of vitamin A is needed to flush the residue Isotretinion from out bodies. I also experienced very few side effects at less than 100,000 iu day

im not sure about this. you might be able to deal with vitamin a/accutane all together differently then some people on here to begin with. hence there really arent too many people that have grazed this forum compared to the millions that have taken accutane. i have also dabbled in higher dose vitamin a, and think it did more harm then good.still have eye floaters from it. so anyone else considering this proceed with caution. but if we did have vitamin a stuck in our cells/liver i would think this would only compound the problem. glad your doing well though.