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On 2/23/2016 at 4:07 AM, hatetane said:A lot of fin guys talk about Bromelain - anyone tried it?
Also some of you have talked about excessive sweating and some not sweating at all. (Are you able to cry?)
It's my understanding that toxins are can be everywhere in the body.
So for the ones that don't sweat, what about taking hyaluronic acid and having some saunas.
Would have to consider loss of other vitamins but as some recoveries state saunas and exercise helped.I read an aticle about accutane and hylauronic acid was mentioned as being possibly helpful in alleviating chronic dryness.
Can't find the article but will post it if i find it.Found it.
[Edited link out]
Any one have any theories on this?
Found the article - pretty horrific reading. Very long so you may find it hard to find paragraph relating
to Hyaluronic acid supplement. At a guess around sentence 15 or soThanks Oli girl.
Found the article but it is very long so you may have trouble finding the bit bit referencing supplementing Hyaluronic Aid.
It's a horrific read - not for the feint hearted.At a guess I would say it is between 12 and 15 sentences down.
T
That is Nathan report! He eventually posted it on that webpage. He has been instrumental in the Accutane community, in fact we have meet and speak frequently! I will look for the name of the Hyaluronic acid brand that is good and let you know. I am not sure about the FIN guys, but I do know a lot of Accutane suffers in the past have tried Bromelain with some success. One of them is long time suffer Patti Lodes (20 something years)!
It doesn't hurt to try 
Gutairman01- no woman should ever get pregnant right after Accutane. Obgyns get so mad at woman who take this drug prior to having kids and it is suggested to wait at least 6 months. That's if you can even get pregnant, many woman including myself have suffered infertility after Accutane. Though no surprise when we know what chemo can do to a woman reproductive organs. Lovely!!!
On 2/23/2016 at 3:12 AM, pabpab said:for the record - I tried RSO (both sativa dominant and indica dominant) and if i ingested it (or took as suppoistories) it gave me anxiety/panic attacks+racing thoughts. Terrible. I tried also so called "tacking" method as shown here : here but my oil coudn;t adhere to the gums.''
Re comment about masturbation - I did 100 days of no fap/no sex. Erections were better but had no libido like always.
I did nofap and my libido did eventually come back, I literally withheld for about 8 months in total. There were some weeks when I would give up but most of the time I was good. Libido defiantly came back, however that may have been through a culmination of other stuff I tried. But for me I can 100% say I have wiped out sexual problems from my long list of symptoms.
I think there is a link between androgen receptors and accutane, perhaps you could look at ways to increase (unblock) there sensitivity.
4 hours ago, koikoi123 said:I did nofap and my libido did eventually come back, I literally withheld for about 8 months in total. There were some weeks when I would give up but most of the time I was good. Libido defiantly came back, however that may have been through a culmination of other stuff I tried. But for me I can 100% say I have wiped out sexual problems from my long list of symptoms.I think there is a link between androgen receptors and accutane, perhaps you could look at ways to increase (unblock) there sensitivity.
koikoi - we need that list of things! How long was ed a prob?
5 hours ago, oli girl said:That is Nathan report! He eventually posted it on that webpage. He has been instrumental in the Accutane community, in fact we have meet and speak frequently! I will look for the name of the Hyaluronic acid brand that is good and let you know. I am not sure about the FIN guys, but I do know a lot of Accutane suffers in the past have tried Bromelain with some success. One of them is long time suffer Patti Lodes (20 something years)!It doesn't hurt to try
Gutairman01- no woman should ever get pregnant right after Accutane. Obgyns get so mad at woman who take this drug prior to having kids and it is suggested to wait at least 6 months. That's if you can even get pregnant, many woman including myself have suffered infertility after Accutane. Though no surprise when we know what chemo can do to a woman reproductive organs. Lovely!!!
Thanks Oli - what a very small world. Can you give me Nathan's email? Don't understand why all of you wouldn't replenish with HA. I wouldn't expect it to cure anything but in terms of maintenance, longevity and skin - it seems so obvious and I would of thought harmless.
What I do know is that i will keep getting expert opinions on everything before trying - lesson learnt. Thanks for your import and appreciate you looking up that brand.
what about probiotics again? high dose of the right strain. maybe we are just sterile so to speak post accutane. what are retinoids/accutanes effects on bacteria? they effect bacteria in the skin, so if they effect this bacteria what about other bacteria? you know the gut, immune system. All these individual supplements seem like small fries and not the big picture. for example i just read a post where probiotics gave this girl horrible acne, oh here it is http://www.mywomenstuff.com/2012/06/can-taking-probiotics-cause-your-skin-to-break-out-and-develop-acne/
my skin got oily as hell the other day and my face almost started to sweat it was either riboflavin, culturelle 15bil over 2 days, or copper which ive taken 6 to 8mgs past couple days. but idk if its the copper. going to still get blood test though. but i say culturelle over vsl atm because its a pure strain, 1 strain the most studied. for example if i take lets say 60 bil per day of culturelle, that might top vsl in terms of 1 single pure strain because noone knows how much lacti gg or similar they put in vsl. i read some study that anything bifi might not be good for sibo if any of us have that. milk/yogurt causes acne cause of hormones, maybe its the bacteria as well. all i got to say is I took 30bill of culturelle not long ago and feel pretty damn good atm.
On 2/23/2016 at 11:40 AM, hatetane said:koikoi - we need that list of things! How long was ed a prob? Thanks Oli - what a very small world. Can you give me Nathan's email? Don't understand why all of you wouldn't replenish with HA. I wouldn't expect it to cure anything but in terms of maintenance, longevity and skin - it seems so obvious and I would of thought harmless.
What I do know is that i will keep getting expert opinions on everythingbefore trying - lesson le arnt. Thanks for your import and appreciate you looking up that brand.
I will pm you his email address. also the brand for Hyaluronic acid that many suffers have tried or take is Baxyl. Some have had relief. Though you probably won't learn anything new regarding Accutane here is a link to the the e-book from Bill Sardi and Matthew Hamilton (suffer) regarding Hyaluronic Acid. For some it has helped and other maybe not. My things is you have to try something for at least 6 months to see improvement. If you have a host of issues it may not just be one things. Outside of diet I had a host of deficiencies so I take quite a bit.
[Edited link out]
I am not sure either but those with fibromyalgia type symptoms or joint pain you can always look at Sheefa's posts. He saw the top derm in the U.K. that has treated some Accutane victims. For eye issues and body wide dryness you look at some of Lamarr1986 post or if you have flushing and hair loss. He had some success with some issues though no cure.
It truly is a shame that the old rag forum disappeared. It was very organized and beneficial. In fact many of these things that are being tried, theories etc. where on there...whether it be copper deficiency or something else.
Those you who aren't familiar with Max proboards on Accutane, you look through it! He was a suffer and was a member on here a long long time ago. I haven't been able to find his postshere on acne.org Spammers have taken over post wise, like most old timers we tend to get tired! I think his last post was in 2009!
I myself have permanent damage from Accutane...I will never get my height back, I will never get my pancreas back, part of my thyroid not to mention my lacrimal glands or the other eye problems. You just have to keep going and do the things you love life is to short!
On the Hyaluronic acid front (HA), I've come across quite a few good things about Baxyl too. Personally, I took HA in tablet form for just over two months and I don't feel I gained much. I purchased a copper supplement last week and Baxyl arrived from the US yesterday. Baxyl is a liquid form of HA which is apparently more bio-available. I took a teaspoon yesterday. As usual, I don't expect much, however, what I will say is that this morning my wakening joint pain wasn't too bad for the first time in about 12 weeks. Too early to say anything in particular though. It could just be part of the endless peak and trough of symptoms or could be related to the copper. If it was to work, it'd only be masking the problem though, as the indication would then be that my body isn't producing enough HA on its own, which would be pretty soul destroying.
I read up more on methylation last night, and it seems that it has the power to turn genes off and on (which is a big fear with accutane). It's primarily about cell proliferation, with various forms of B12 being a catalyst for optimizing processes. This is the reason that folic acid is recommended to pregnant women, because slow cell proliferation can cause defects like cleft palate and Spinebifida. Increased proliferation insures that the baby develops at a good rate. If it's that powerful, maybe it can bring any expression damage back in the right direction? It seems a lot of people are claiming that it has had quite marked effects. The researchers quote osteoperosis as a disease of slow proliferation, which it pains me to hear that you suffer from Oli Girl. If a lot of problems (like joint pain) are in anyway caused by slow proliferation, (which would make sense as one thing that is agreed about accutane is that it slows down the turn over of skin cells, making less dead cells present for bacteria to feed on). If these problems are a function of slow proliferation, then speeding up the proliferation pathways could only help, particularly in places such as the joints, where cell turnover is already low. Like I said, a lot of my own personal symptoms, I originally suspected a B12 issue (dry mouth, hairloss, dry eyes, joint pain), so it's definitely something I'll look into, on top of attempting to restore my gut flora.
33 minutes ago, dakiramir said:On the Hyaluronic acid front (HA), I've come across quite a few good things about Baxyl too. Personally, I took HA in tablet form for just over two months and I don't feel I gained much. I purchased a copper supplement last week and Baxyl arrived from the US yesterday. Baxyl is a liquid form of HA which is apparently more bio-available. I took a teaspoon yesterday. As usual, I don't expect much, however, what I will say is that this morning my wakening joint pain wasn't too bad for the first time in about 12 weeks. Too early to say anything in particular though. It could just be part of the endless peak and trough of symptoms or could be related to the copper. If it was to work, it'd only be masking the problem though, as the indication would then be that my body isn't producing enough HA on its own, which would be pretty soul destroying.
I read up more on methylation last night, and it seems that it has the power to turn genes off and on (which is a big fear with accutane). It's primarily about cell proliferation, with various forms of B12 being a catalyst for optimizing processes. This is the reason that folic acid is recommended to pregnant women, because slow cell proliferation can cause defects like cleft palate and Spinebifida. Increased proliferation insures that the baby develops at a good rate. If it's that powerful, maybe it can bring any expression damage back in the right direction? It seems a lot of people are claiming that it has had quite marked effects. The researchers quote osteoperosis as a disease of slow proliferation, which it pains me to hear that you suffer from Oli Girl. If a lot of problems (like joint pain) are in anyway caused by slow proliferation, (which would make sense as one thing that is agreed about accutane is that it slows down the turn over of skin cells, making less dead cells present for bacteria to feed on). If these problems are a function of slow proliferation, then speeding up the proliferation pathways could only help, particularly in places such as the joints, where cell turnover is already low. Like I said, a lot of my own personal symptoms, I originally suspected a B12 issue (dry mouth, hairloss, dry eyes, joint pain), so it's definitely something I'll look into, on top of attempting to restore my gut flora.
Thanks Dak, where are you from? Yetanotheraccutanevictim is a good person to speak to about methylation and I recommend you speak to Dr Jess Armine about methylation- you get a free 15 call with no obligation. Can you let me know how you get on with thre HA. I am looking more into this so will let you know what I find.
On 2/22/2016 at 9:48 AM, ViceCaz said:If you used CBD oil it would be not the way to go . Rick Simpson oil is nearly full of THC, with Indica strains .
RSO have cured many disease, Crohn, cancer, leukemia, glaucom etc. There is only benefits you can have from this oil. But this is really different compare to CBD oil.
moreover recent study have showed that high dose vitamin A can lead to cell death or cell damages. When there is so many people claiming free of disease like cancer after having used cannabis oil ( by Rick Simpson ) it makes sense..same question about tanedout, which oil did he use? How long?
Thanks for the information about Doneat16 and Crank92. I did not know about Crank
what side effects had Doneat16? Is he still ok recently?I dont know about Dave, but I dont think doing a 14/22 days water fast would be enaugh to recover. There is a lot to do , not only cannabis oil is a cure. Not only water fast is a cure . Not only diet change is a cure. It is the addition of it
the man who recovered in France really did a lot of things to recover. He is claiming that what have been the more effective is : kidney and liver flush. He performed two kidney flush and 10/12 liver flush .
He followed at least one year a really strict vegan diet with a lot of juice of fresh vegetables / fruits.
'He followed the 3 months protocol of Dr Morse, used glandular , sun exposure, sports, sauna, coconut oil, Isotherapy ( no one talking about this in this thread, is it only well known in France ? ) red skate liver oil, homeopathy for vaccine like hepatit B ..he also used many herbs like curcuma, desmodium, milk thistle, cascara saggrada etc.
He had taken accutane for six months at 40 mgs . What about you?
for the little story, i smoke a bit marijuanna in December, and the day after I got an erection for the first time since one year . I dont know if it is a coincidence or not but I dont think so.
I will try this oil next year. I cant before. I have to go in Colorado and be sure of the quality of the oil.
Is the french guy Victor?
16 hours ago, guitarman01 said:i think what alot of us are suffering is an indirect effect caused by accutane, maybe not a direct effect of the drug itself. I had no depression, eye sensitivity, hair loss, concentration problems, anxiety while on the drug. it wasnt till months off it, i started noticing diff things. and the drug would have been gone by this time. hell girls can get pregnant just days after stopping accutane i believe and not have problems.
this makes sense because i think some of our brain fog is due to over production of mucus and histimine
i aint saying much yet but im not ruling out a copper deficiency myself yet either, will get tested soon. alot of us have pale skin post tane, loss of hair color and quality, and histamine problems, copper can tie into alot of things including methylation. tryingtohelp is still pimping copper but he loves pimping his own research so we will see.I might be feeling good effects from copper, to soon to say for sure. also recent study that a copper defect may cause altogether nearsightedness .
Also, anyone have any true/accurate/informed theories as to how long accutane lasts in the body? I quote you here Guitarman because I read a study a while back about a lady who took substantial quantities of vitamin A and ended up with hypervitaminosis. She had a load of side effects that seemed to subside when she stopped, but it seems it took a while, and when they tested her vitamin A levels 18 months later, I remember the levels were still wayyyyyyy higher than normal, I'm sure it was like 4 times higher or something. I can't find the journal article which is driving me crazy.
I bring this up because I'm sure many of us with joint pains at times have wondered about (and been tested for) Lupus. I know Oli Girl says she tested positive for a while after stopping. And there have been other cases on acne.org alone. What I'm saying here is, if accutane is stored in any way similarly to vitamin A (in fat and in the liver), and accutane has been linked to DILE (drug induced lupus), then unlike other lupus inducing medications, that would leave the bloodstream fairly soon after stopping, accutane that was stored in the fat would almost drip feed the element that caused the lupus even after stopping. Especially for those six months when many derms often say the drug is still active. So if DILE occurred, would stopping the drug actually lead to an immediate improvement of symptoms? I ask this because it can sometimes take a long period of exposure to a drug to induce DILE, so if you were to stop taking the drug, but the drug was stored, then the exposure wouldn't end, and would reflect why there would be a latency in developing symptoms similar to lupus? I've seen that DILE can take up to a year after stopping to fully recover, so I have no idea how long it would take if you had to wait for stored levels of the instigating drug to dissipate first. Bear in mind that Lupus is a set of symptoms with a name. We're all dealing with various sets of symptoms that often don't have a name, so just because I'm using lupus as an example, doesn't mean that I'm referencing lupus involvement for everyone, just using it as a working example to ask how on earth you'd recover from a drug induced syndrome, if the drug had some capacity for storage?
In those that don't experience those sort of symptoms, maybe it's simply down to the effects of long term exposure to high levels of vit A after stopping (causing stress to the body/knocking minerals and vitamins out of whack etc). I've looked all over the web and I've heard some derms say it's gone in a few days, some say in a few weeks, some it takes a month, some it takes a few months, some it takes 6 months, another said it can take up to a year and I've seen a quote somewhere on here that their derm said that the beauty of it was that "it never really leaves". Whatever we're dealing with, if there's a capacity for storage, then recovery probably wouldn't really start until after levels lowered, and maybe only after that time would it start being possible to address the damage to various mineral and vitamin deficiencies within the body.
I have also started on copper and will report any improvement.
The above also ties in with Hatetane's methylation posts, in that as well as speeding up cell proliferation, there is also a pathway that is fundamental to detoxification and immune responses. The process uses Methionine to bind to toxins before they are excreted. I'm kind of coming with you on this Hatetane, because the science is getting behind this research, and the methylation pathways seem to tie in directly with the detoxification of fat soluable toxins (i've taken a simplified version and attached it below, rather than one of the huge pathway maps that are usually put together).
Dak
On 23 fevrier 2016 at 0:59 PM, hatetane said:Thanks Dak, where are you from? Yetanotheraccutanevictim is a good person to speak to about methylation and I recommend you speak to Dr Jess Armine about methylation- you get a free 15 call with no obligation. Can you let me know how you get on with thre HA. I am looking more into this so will let you know what I find. Is the french guy Victor?
I m confused, what do you mean?
my name is Victor, and the french man took accutane 6/8 years ago. He wrote a huge blog about his recovery from accutane.
He even wrote in this thread two years ago to share his story
13 hours ago, dakiramir said:If it was to work, it'd only be masking the problem though, as the indication would then be that my body isn't producing enough HA on its own, which would be pretty soul destroying.
I read up more on methylation last night, and it seems that it has the power to turn genes off and on (which is a big fear with accutane). It's primarily about cell proliferation, with various forms of B12 being a catalyst for optimizing processes.
B12 is not the only cataylst. a b12 + methylmalonic acid test can 100% rule out b12 deficiency.
forget everything you read on the interwebs about copper toxicity. youve taken accutane!! you dont have it! GET TESTED!
accutane does two things very well:
1. it raises the ATP7A enzyme (this has the opposite effect as ATP7B or wilsons disease) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634674/
2. 13-cis retinoic acid induces ceruloplasmin 4x the normal level during treatment http://www.ncbi.nlm.nih.gov/pubmed/3655940 and this process stops as you become deficient in copper
now #1 could very well be related to #2. 1. removes copper from the cell (efflux.) 2.could be the copper, that was removed from the cell, binding it for excretion.
both of these deplete or bind to copper. I REPEAT, this is why accutane is a chemotherapy drug. theyve found that by introducing other copper chelators while on accutane, cause cancer cells to stop proliferating even faster. This would also cause a methionine restriction by an indirect methionine synthase deficiency. this is a known cancer fighting strategy.... methionine restriction.
if you have any type of numbness after accutane, you probably have some type of peripheral neuropathy (yes this might be permanent nerve damage)...not too far away from full blown myelopathy
GET TESTED!
so by this chart, Methylation is greatly inhibited (by up to 80%) if you dont have the cofactors needed to produce methionine synthase. you would constantly have to introduce high amounts of SAM-E because the SAH doesnt get recycled back to methionine to naturally produce more SAM-E. now its also been WELL documented that accutance throws off the SAM/SAH balance. so this would fit.
then you could really go down the wormhole....
purine synthesis ---> NADH --->NADH is needed for---retinol dehydrogenase.....
"Some retinol dehydrogenases are in extra-ocular tissues, such as human retinol dehydrogenase-4 (RoDH-4), which converts retinol and 1-cis-retinol to different aldehydes in liver and skin. It was also found that 13-cis-retinoic acid (isotretinoin), 3,4-didehydroretinoic acid, and 3,4-didehydroretinol can act as competitive inhibitor of the 3±-hydroxysteroid dehydrogenase oxidative activity of the enzyme. This can potentially explain how isotretinoin, the active ingredient is Roaccutane (Accutane), can suppresssebaceous glands and be used for severe acne treatment.[15]
CH3CH2OH + NAD+ †’ CH3CHO + NADH + H+
.....
Remember vitamin A is an alcohol...so when you feel better after drinking, you are promoting an alcohol reducing detoxification pathway. Feeling noticeably better after drinking(in our specific accutane cases), would almost confirm a highly burdened body of retinyl esters.
....
This allows the consumption of alcoholic beverages, but its evolutionary purpose is probably the breakdown of alcohols naturally contained in foods or produced by bacteria in the digestive tract.[19]
Another evolutionary purpose may be metabolism of the endogenous alcohol vitamin A (retinol), which generates the hormone retinoic acid, although the function here may be primarily the elimination of toxic levels of retinol.[20][21]
it took them 10+ years to put a disclaimer in commercials for Nexium (that little purple pill)... that it depletes magnesium, causing all types of problems. people were breaking bones!! Accutane will be proven to be the same.
So taking copper 6 to 8mgs per day is really decongesting my nose. So much my nose hurts lol. this effect is stronger then any drug I've taken. Based on what I've noticed idk if I can go higher then 4mgs per day atm. Waiting to get blood tested atm. Shit the test said ceroplasim or something. Was this the wrong test? I told her rbc copper
Hi guys,
I've decided to stop taking isotretinoin tomorrow. My hair has been getting more diffuse on top, especially during this past month. I had MPB before taking isotretinoin, but I know the medication is making it much worse.
I was wondering if anyone has experience with hairloss, and if it did indeed get better after stopping the medication? I know that isotretinoin is an ex chemo drug, so this is all to be expected I suppose. I always get the bad side effects.
I will have taken isotretinoin for 175 days and my cumulative dose will be 11,530mg. I weigh 69kg.
5 hours ago, ViceCaz said:I m confused, what do you mean?
my name is Victor, and the french man I'm talking about is boris and took accutane 6/8 years ago. He wrote a huge blog about his recovery from accutane.
He even wrote in this thread two years ago to share his story
I m regularly talking with him , are u interested having his mail ?
5 hours ago, ViceCaz said:I m confused, what do you mean?
my name is Victor, and the french man I'm talking about is boris and took accutane 6/8 years ago. He wrote a huge blog about his recovery from accutane.
He even wrote in this thread two years ago to share his story
I m regularly talking with him , are u interested having his mail ?
LOL. The french guy is Victor Detraz - that's not you right? Yes, I want to talk to anyone who has recovered. Thanks.
6 hours ago, dakiramir said:Also, anyone have any true/accurate/informed theories as to how long accutane lasts in the body? I quote you here Guitarman because I read a study a while back about a lady who took substantial quantities of vitamin A and ended up with hypervitaminosis. She had a load of side effects that seemed to subside when she stopped, but it seems it took a while, and when they tested her vitamin A levels 18 months later, I remember the levels were still wayyyyyyy higher than normal, I'm sure it was like 4 times higher or something. I can't find the journal article which is driving me crazy.I bring this up because I'm sure many of us with joint pains at times have wondered about (and been tested for) Lupus. I know Oli Girl says she tested positive for a while after stopping. And there have been other cases on acne.org alone. What I'm saying here is, if accutane is stored in any way similarly to vitamin A (in fat and in the liver), and accutane has been linked to DILE (drug induced lupus), then unlike other lupus inducing medications, that would leave the bloodstream fairly soon after stopping, accutane that was stored in the fat would almost drip feed the element that caused the lupus even after stopping. Especially for those six months when many derms often say the drug is still active. So if DILE occurred, would stopping the drug actually lead to an immediate improvement of symptoms? I ask this because it can sometimes take a long period of exposure to a drug to induce DILE, so if you were to stop taking the drug, but the drug was stored, then the exposure wouldn't end, and would reflect why there would be a latency in developing symptoms similar to lupus? I've seen that DILE can take up to a year after stopping to fully recover, so I have no idea how long it would take if you had to wait for stored levels of the instigating drug to dissipate first. Bear in mind that Lupus is a set of symptoms with a name. We're all dealing with various sets of symptoms that often don't have a name, so just because I'm using lupus as an example, doesn't mean that I'm referencing lupus involvement for everyone, just using it as a working example to ask how on earth you'd recover from a drug induced syndrome, if the drug had some capacity for storage?
In those that don't experience those sort of symptoms, maybe it's simply down to the effects of long term exposure to high levels of vit A after stopping (causing stress to the body/knocking minerals and vitamins out of whack etc). I've looked all over the web and I've heard some derms say it's gone in a few days, some say in a few weeks, some it takes a month, some it takes a few months, some it takes 6 months, another said it can take up to a year and I've seen a quote somewhere on here that their derm said that the beauty of it was that "it never really leaves". Whatever we're dealing with, if there's a capacity for storage, then recovery probably wouldn't really start until after levels lowered, and maybe only after that time would it start being possible to address the damage to various mineral and vitamin deficiencies within the body.
I have also started on copper and will report any improvement.
The above also ties in with Hatetane's methylation posts, in that as well as speeding up cell proliferation, there is also a pathway that is fundamental to detoxification and immune responses. The process uses Methionine to bind to toxins before they are excreted. I'm kind of coming with you on this Hatetane, because the science is getting behind this research, and the methylation pathways seem to tie in directly with the detoxification of fat soluable toxins (i've taken a simplified version and attached it below, rather than one of the huge pathway maps that are usually put together).
Dak
Looks so simple - if only!
3 hours ago, deletemyacne said:Hi guys,
I've decided to stop taking isotretinoin tomorrow. My hair has been getting more diffuse on top, especially during this past month. I had MPB before taking isotretinoin, but I know the medication is making it much worse.
I was wondering if anyone has experience with hairloss, and if it did indeed get better after stopping the medication? I know that isotretinoin is an ex chemo drug, so this is all to be expected I suppose. I always get the bad side effects.
I will have taken isotretinoin for 175 days and my cumulative dose will be 11,530mg. I weigh 69kg.
Hi Deletemyacne - If you already had MPB before taking Accutane, then chances are it made it worse. Most that have recovered or gotten somewhat better from hair loss had hormonal issues or TE. You can look at some of Lamarr1986 and there is a hair loss thread you look on this link! I do know that there are some Accutane victims who have taken propecia etc. with success for MPB, but I would NOT recommend it as some have suffered worse etc.Also, someone mentioned about Accutane staying in the system...I don't know many theories out there vice versa. I do know Roche themselves claims that the medication continues to work up to 3 months after stopping your course. Of course they claim mechanisms unknown! Lovely I know!!!!!!!!!!!!
22 minutes ago, oli girl said:Also, someone mentioned about Accutane staying in the system...I don't know many theories out there vice versa. I do know Roche themselves claims that the medication continues to work up to 3 months after stopping your course. Of course they claim mechanisms unknown! Lovely I know!!!!!!!!!!!!
on Baxyl.... the dosage on the bottle says 30mg hyaluronan daily
From Wiki....
The average 70kg (154lb) person has roughly 15grams of hyaluronan in the body, one-third of which is turned over (degraded and synthesized) every day.[4]
you would have to take 5 grams of baxyl daily (166 doses a day, almost 3 full bottles.) on top of that, oral hyaluronic acid is poorly absorbed. thats if our bodies made 0. obviously we make some.
i remember looking at this... and then looking at probiotics , specifically ones withsubtilis bacillus. these guys actually produce hyaluronic acid in fermentation.
either copper or culturelle is making my skin at least forehead more oily, which I view as a good thing. I'll quit the probiotic and see if its the copper. im going to shoot for 6 to 8mg per day divided of copper. will have to wait a week for blood test results. but this copper is decongesting my nose and hopefully sinuses and ears like nothing else. so for this effect alone I have to say I feel pretty good about copper atm.
Just thought I'd throw in another symptom I've been suffering with lately: my brain burns when looking at a computer monitor for more than an hour. It burns right in the prefrontal cortex area. I've heard that this indicates mitochondrial strain/dysfunction - and seeing that the prefrontal cortex is one area of the body that concentrates a high number of mitochondria per cell, this would make sense.
Be cautious about copper:
Hopefully everyone here tests themselves before getting on high-dose copper. Some may suffer from kryptopyrroluria(KPU) which causes a high loss of zinc in the urine. Ingesting copper would only aggravate this problem.
Pay attention to the nails. Any white spots? How is your dream recall? Did you ever experience a trauma? Do you have Lyme symptoms? Any of these can indicate the presence of this condition. Just a word of warning.
*I must note, though, that according to what I've seen from Tryingtohelp2014 and others, we are almost all copper deficient, especially if Accutanehas ever been ingested.Don't start supplementing copper until you've been tested to be safe. Plus, it'd likely mess up the results if you started supplementing THEN you tested.
10 hours ago, guitarman01 said:happened to that dude that was using cyclodextrin ? walden15 was it? you alright my man? when I think about what he was doing that might have been
No man, I'm still doing pretty good. Just ordered my next batch because I think with every gram I put up my bum 1/10th is absorbed. I have to keep laying on my belly otherwise with walking Im losing some fluids.
I'm not very consistent with dosing most of the time I'm doing it before bed
As for the effects.
- Losing belly fat which I couldnt with cardio
- Increased nail growth
- ALOT of dreaming
And started with NoFap to give that Androgen/Hormone pathway some rest.
Good luck everybody on your endeavors
9 hours ago, Walden Rev said:No man, I'm still doing pretty good. Just ordered my next batch because I think with every gram I put up my bum 1/10th is absorbed. I have to keep laying on my belly otherwise with walking Im losing some fluids.
I'm not very consistent with dosing most of the time I'm doing it before bedAs for the effects.
- Losing belly fat which I couldnt with cardio
- Increased nail growth
- ALOT of dreamingAnd started with NoFap to give that Androgen/Hormone pathway some rest.
Good luck everybody on your endeavors
I found something VERY interesting and could be related.
accutane upregulates copper anime oxidase over 3x the normal level during treatment. WHY??? now when you start researching this oxidase.. it starts explaining what theyre used for. in plants , whenever they get wounded, the same oxidase gets upregulated as well. it mechanically heals wounds and strengthens cell walls. in mammals its used for detoxification....it binds to toxicants (xenobiotic animes) and is used in the formation of aldehydes.
in fact it gets upregulated the same exact amount as the P450 retinoid metabolizing enzyme. WHY??? If I could ask a "professional" researcher one question, this would be the one.
Amine oxidases and monooxygenases in the in vivo metabolism of xenobiotic amines in humans: has the involvement of amine oxidases been neglected? http://www.ncbi.nlm.nih.gov/pubmed/17868200
whats even more interesting is the structure of one of these copper oxidases....
look familiar to cyclo?! now what if this oxidase is upregulated to somehow bind with accutane, and in doing so, gets used up, depleting us of the intracellular copper?
ok so it might have been the probiotic that made my skin more oily not the copper. was taking 30bil of culturelle and damn this was only a couple days. imagine a higher dosage or use for at least a week. it seems like allergy type symptoms ie running nose go crazy with a little higher dosage copper still trying to determine if this is a good thing(decongesting) or bad thing. (irritating to the respiratory tract)
im going to forget about copper for the moment and just pump my self with a shit ton of culturelle at least 30 to 60bil total twice a day.
http://www.culturelle.com/blog/single-strain-probiotics-vs-multi-strain-options