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Repairing the long-term damage from Accutane

 
MemberMember
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(@manalesenicola)

Posted : 12/12/2015 9:51 am

About a week ago I got a prescription for 5 mg of Cipralex a selective serotonin reuptake inhibitor (SSRI). Cipralex is generally used to treat depression, OCD, and generalized anxiety disorder. I dumped all my nutritional supplements as well. I take one 5mg pill a day now.

After a week of being on anti depressants, and 3 weeks of NoFap (this helps with anxiety as well) I have noticed:

- No more hairloss

- Psoriasis/seb derm is the clearest it has ever been

- Rosacea is almost gone (im also using finacea gel)

- jaw and ankle popping have stopped popping

- skin feels moist

- I ate like shit these past couple days and have had the greatest most rewarding poos of my entire life. srsly.

- I am getting spontaneous erections in the day, and morning wood...my libido is back. (usually anti - depressants can have a lowering libido side effect)

- back pain/shoulder pain lowering it feels like i can hold my head up in a better position

- what I really notice and other friends as well is that my eyes are more "alive"... I no longer have white bumpy lines and dark patches underneath my eyes. I can open them more and I just look younger I think.

- and the best thing I have noticed...NO MORE DAM BRAIN FOG. I am optimistic about my future now...have fun talking to people etc.

I really stress that everyone here look into anti depressants. At first I thought i was in a manic funk from the SSRI, but people have commented on my appearance and my Dad was the one who told me my jaw stopped popping during meals. For me its starting to be happy mind = healthy body. We have been through a lot due to this drug so please look into anti depressants. I'm not claiming them to be a cure for all of our struggles but over the past week i can't believe what is happening to me, i'm almost in tears... it feels like i somewhat have my life back.

After telling my doctor of my accutane sides diminishing, she said that serotonin and collagen production can be linked together. If anyone wants to expand on that feel free = ) .

I will check back in to let you guys know if my symptoms are still diminishing.

Cheers

This is a Post from the past time from a guy who has used accutane, and curehis sides with ssri.

Think about it. Foxo1 is downregulated by serotonergic drugs maybe this would be the cause of his cure.

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MemberMember
231
(@fchawk)

Posted : 12/12/2015 10:02 am

This is in response to an email asking about what someone can do a year after taking a relatively small dose of Accutane (<200mg in total), and still having negative side effetcs. Primary concerns were long term sexual function, hormonal balance, and bone growth. I think we can all agree on the first paragraph

I would say the first two treatments I would take would be Taurine and Creatine, as well as BCAAs(Branched-Chain Amino Acids). I believe many of the symptoms of Isotretinoin (Accutane) are caused by our body struggling to manufacture these proteins. Height wise, there is not much I can recommend, and I am not knowledgable on the subject.(in relation to the possibility of stumped growth from accutane, keeping in mind they only had a few treatments)

Next bit is a bit more speculative

I took it when I was 16, but I was already 6'4, and grew 1 more inch after treatment, finishing at 6'5. Maybe I would have grown taller, But I think I was very close to finishing anyway. In any case I went on high dose for months, and I believe that growth problems that occur from Isotretinoin are from it attaching to retinoic acid receptors in your bones, changing the way your body metabolises calcium, etc. I think the dosage would need to be quite great to do that, and from my educated GUESS something you could to to counteract it would be to start supplementing Vitamin D at 3000 IU per day, as it encourages bone formation. Perhaps take 10,000IU of vitamin A per day as well, and this is the most I can recommend with a completely clear conscience, as after this it is not only completely speculative, but there are possible, albeit minor, health risks involved

An email to a different forum member asking how I was going with my treatment of megadosing vitamin A, which i would argue is the most promising cure to the damage caused by megadosing Isotretinoin. For the last 6 weeks I have been averaging ~100,000IU per day, which is 30mgRE(retinoic equivalent), or 45mg Retinyl Palmitate, keeping in mind Isotretinoin dosage was 80mg per day.(according to this it would take 1,000,000 IU per day to replicate the side effects of 1-2mg/kg/day  http://escholarship.org/uc/item/88t998r8 ) Also keep in mind the Acute effects of vitamin A toxicity don't have long term effects, the thing to watch out for is chronic toxicity, but it is generally accepted (4000IU/kg(100 for me))/day for 6 months is what it takes to induce that

(This is an email I sent to another forum member validating why I myself have taken more than 4 Million IU of vitamin A in the last 6 weeks. The main problem for you is extremely high vitamin A consumption can cause bone loss, which may not help your growth dilema, however, this should be combatable by increasing vitamin D intake as well. I usually only had 5-10,000 IU. Google:vitamin d "vitamin A" toxic, and educate yourself so you are completely aware of the risks, though I specifically got much out of this article, though the author is pro-vitamin A like me [Edited link out]

Anyway, read below, and remember, this is my opinion, I am still early days in my own experiment so I can't give any conclusive recommendation)

In the last 6 weeks since I have started supplementing vitamin A, the main change I have seen physically is slightly but noticeable increase in body hair growth. I have stopped applying vitamin A topically to see whether it was from consumption or topical application, and so far it does seem like it was the consumption causing it, though topical application may have helped as well

http://www.ncbi.nlm.nih.gov/pubmed/8175961  (Isotretinoin reduces DHT(androgen 5 alpha-reduction, not specifically DHT) production by 80% in skin and substantially in liver as well)

http://www.ncbi.nlm.nih.gov/pubmed/2943822 (Isotretinoin affects endogenous Vitamin A metabolism in the skin. Begs the question what it is doing in liver as well)

Personally, I do believe that Isotretinoin affects our bodies ability to metabolise vitamin A and its derivatives, whether by inducing sensitivity to some effects of it, or causing our body to process and excrete all retinoids quicker, causing a deficiency (can't be bothered looking it up, but it has to do something with increased enzyme levels that help process retinoids), or by attaching itself to retinoid receptors and being itself causing exaggerated or diminished effects, as supported by this study ( http://www.ncbi.nlm.nih.gov/pubmed/10951254 ).

 

Last but not least, I am of the opinion that having larger spikes of vitamin A consumption is the best way to make the body cleanse itself of Istretinoin, and allow a redistribution of retinoids on the retinoid acid receptors, hopefully allowing us to regain equilibrium.  http://www.ncbi.nlm.nih.gov/pubmed/16243460  (Showing single doses of 10,000 IU+ give a response in the levels of retinol, retinyl esters or retinoic acids in plasma, which is what I want, though I might take doses anywhere up to 4000 IU/KG, or 400,000 IU in one sitting)

 

Thats all, I think I agree with the majority of people here until I go on my Vitamin A train, whereby I happily distinguish myself as an extremist, and so I allow myself to potentially crash and burn in your place but hopefully I am on the right track (Would be happy in anyone was on the right track). Physically I am feeling stronger, fitter and healthier than ever, can't wait to get my hands on some taurine.

 

On 12/12/2015 at 10:51 PM, manalesenicola said:

About a week ago I got a prescription for 5 mg of Cipralex a selective serotonin reuptake inhibitor (SSRI). Cipralex is generally used to treat depression, OCD, and generalized anxiety disorder. I dumped all my nutritional supplements as well. I take one 5mg pill a day now.

After a week of being on anti depressants, and 3 weeks of NoFap (this helps with anxiety as well) I have noticed:

 

- No more hairloss

- Psoriasis/seb derm is the clearest it has ever been

- Rosacea is almost gone (im also using finacea gel)

- jaw and ankle popping have stopped popping

- skin feels moist

- I ate like shit these past couple days and have had the greatest most rewarding poos of my entire life. srsly.

- I am getting spontaneous erections in the day, and morning wood...my libido is back. (usually anti - depressants can have a lowering libido side effect)

- back pain/shoulder pain lowering it feels like i can hold my head up in a better position

 

- what I really notice and other friends as well is that my eyes are more "alive"... I no longer have white bumpy lines and dark patches underneath my eyes. I can open them more and I just look younger I think.

- and the best thing I have noticed...NO MORE DAM BRAIN FOG. I am optimistic about my future now...have fun talking to people etc.

 

I really stress that everyone here look into anti depressants. At first I thought i was in a manic funk from the SSRI, but people have commented on my appearance and my Dad was the one who told me my jaw stopped popping during meals. For me its starting to be happy mind = healthy body. We have been through a lot due to this drug so please look into anti depressants. I'm not claiming them to be a cure for all of our struggles but over the past week i can't believe what is happening to me, i'm almost in tears... it feels like i somewhat have my life back.

 

After telling my doctor of my accutane sides diminishing, she said that serotonin and collagen production can be linked together. If anyone wants to expand on that feel free = ) .

 

I will check back in to let you guys know if my symptoms are still diminishing.

 

Cheers

 

 

 

 

This is a Post from the past time from a guy who has used accutane, and cure his sides with ssri. 

Think about it. Foxo1 is downregulated by serotonergic drugs maybe this would be the cause of his cure. 

Good luck, keep it up!

We're all gonna make it :) 

On 12/4/2015 at 5:29 AM, SaffronAide said:

Is there any other safe DHT boosters ?

i have low semen volume problem and im scared to grow less.  I think my T and DHT decreased , because i have low semen volume and this problem directly associate with hormones ! 

is there any other advice for me ?

i dont want to use another drug , like antidepressants !

Safest DHT booster is creatine. I've heard boron can be good as well, but haven't  used it personally

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0
(@Anonymous)

Posted : 12/12/2015 10:21 am

My taurine arrived today, going to take 3g split into two doses. Will post updates.

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MemberMember
231
(@fchawk)

Posted : 12/12/2015 10:32 am

On 10 December 2015 5:07:47 am, sam1w2e said:

 

But are you certain it's vitamin A deficiency and not toxicity? Because the symptoms seem very similar for both, and I wouldn't want to go taking more vitamin A if I don't need it.

 

Yo, just read what I've written above. The things that are likely to help include Taurine(pivotal in vitamin A regulation), Creatine can increase DHT and testosterone, and BCAAs help as well, particularly Leucine. I am pro-vitamin A, having taken 4 million IU in the last 6 weeks, though if you do not want to have so much, at very least take a little, because I could take the amount I've taken over the last 6 weeks and have them in two weeks, and continue that level of consumptionfor 6-18 months before I will suffer from chronic toxicity. At the level I am taking them now I could continue for years, although I don't think I will need to because I feel I have already gained some small benefit in the last 6 weeks(see above)

 

http://www.ncbi.nlm.nih.gov/pubmed/10951254 (Isotretinoin can bind to retinoid acid receptors, and even though it usually has a lower affinity for those receptors, due to the massive concentrations of it, especially relative to its usual concentration, it is prioritised. Simplified, my theory is that by taking so much vitamin A, I can induce a "The world ain't big enough for the both of us" scenario where Isotretinoin is kicked out of my system by all the other retinoic acids)

http://escholarship.org/uc/item/88t998r8 (Isotretinoin can cause symptoms of Vitamin A deficiency).

Anyway, seems to be more life and optimism on the forum than I've seen before, keep it up!

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MemberMember
13
(@alantookaccutanewow)

Posted : 12/12/2015 10:41 am

Do NOT take antidepressants. You've been warned! They will mess with more chemicals in your brain and also generally leave you feeling more numb and unhuman in the end. This goes for most prescription drugs (as we've learned).

 

Do NOT take any pills.

 

You can with enough effort (shopping:knowing people, and of course hunting gathering skills) get every amino acid, vitamin, variety, that you need to wake up feeling refreshed, each day, and dealing with whatever comes your way on a totally awesome energeticlevel.

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MemberMember
231
(@fchawk)

Posted : 12/12/2015 10:48 am

5 minutes ago, AlanTookAccutaneWow said:

Do NOT take antidepressants. You've been warned! They will mess with more chemicals in your brain and also generally leave you feeling more numb and unhuman in the end. This goes for most prescription drugs (as we've learned).

Instead, lets try to compromise the mental health of already emotionally vulnerable people even more!!

10/10 troll, ignore. Still do look into taking taurine and stuff the other guys recommend as well :) 

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MemberMember
13
(@alantookaccutanewow)

Posted : 12/12/2015 10:53 am

1 minute ago, Fchawk said:

Instead, lets try to compromise the mental health of already emotionally vulnerable people even more!!

10/10 troll, ignore. Still do look into taking taurine and stuff the other guys recommend as well :) 

 

I am not a troll and you can go away now' I've had it until the end. Still look into NOT taking suppliments and eating raw food. 

 

Who do do you believe? It's not a pressured question I mean to whoever is reading, WHO do you believe! The people suggesting synthetic supplementation or the people suggesting they've felt generally more happy and well, lol eating real life. 

Quote
0
(@Anonymous)

Posted : 12/12/2015 11:06 am

21 minutes ago, Fchawk said:

Yo, just read what I've written above. The things that are likely to help include Taurine(pivotal in vitamin A regulation), Creatine can increase DHT and testosterone, and BCAAs help as well, particularly Leucine. I am pro-vitamin A, having taken 4 million IU in the last 6 weeks, though if you do not want to have so much, at very least take a little, because I could take the amount I've taken over the last 6 weeks and have them in two weeks, and continue that level of consumptionfor 6-18 months before I will suffer from chronic toxicity. At the level I am taking them now I could continue for years, although I don't think I will need to because I feel I have already gained some small benefit in the last 6 weeks(see above)

 

http://www.ncbi.nlm.nih.gov/pubmed/10951254 (Isotretinoin can bind to retinoid acid receptors, and even though it usually has a lower affinity for those receptors, due to the massive concentrations of it, especially relative to its usual concentration, it is prioritised. Simplified, my theory is that by taking so much vitamin A, I can induce a "The world ain't big enough for the both of us" scenario where Isotretinoin is kicked out of my system by all the other retinoic acids)

http://escholarship.org/uc/item/88t998r8 (Isotretinoin can cause symptoms of Vitamin A deficiency).

Anyway, seems to be more life and optimism on the forum than I've seen before, keep it up!

 

Thanks for the response, just read what you've written.

I took between5,000 and 10,000IU of vitamin A a day (through cod liver oil) for about a month back in August, but I didn't really notice anything. I definitely think I've got some issues with fat malabsorption, so if taurine helps with that then I might revisit supplementing vitamin A.

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MemberMember
960
(@tryingtohelp2014)

Posted : 12/12/2015 12:36 pm

2 hours ago, Fchawk said:

 

 

Thats all, I think I agree with the majority of people here until I go on my Vitamin A train, whereby I happily distinguish myself as an extremist, and so I allow myself to potentially crash and burn in your place but hopefully I am on the right track (Would be happy in anyone was on the right track). Physically I am feeling stronger, fitter and healthier than ever, can't wait to get my hands on some taurine.

 

Good luck, keep it up!

We're all gonna make it :) 

Safest DHT booster is creatine. I've heard boron can be good as well, but haven't  used it personally

'

Listen, i believe that taurine is the start of a long reaction.  One of the main  reactions is the ability to absorb fats again.  this will naturally include Vitamin A D E K.   so i would stop all vitamin A supplementation while on taurine.  thats my opinion. i could totally be wrong about that.   you wont need to take any extra fat soluable vitamins... your body will naturally start to absorb these at its own pace.  you could be hampering your bodies detoxification process by adding something else to get rid of.   i think the taurine needs time.  so everyone asking me if its ok to take extra vitamin D... no.  

 

but i do believe everything starts with this step.  by upregulating the PI3K/AKT pathways, we will naturally kick the upregulated FOXO1 out of the nucleus... ending a lot of our side effects.  now this includes that whole list of supplements....and a lot of us have already gravitated towards these compounds for different reasons anyway... taurine creatine DHA ,bcaas, colostrum, tudca TMG etc etc.

 

the one reason i focus on taurine is... out of all of the PI3K/AKT promoters, it also has the proven vitamin A conjugation aspect.  it is specifically listed as a treatment for hypervitaminosis A.  this is also the reason i focused on manganese.  accutane is only conjugated in one of two ways.  one is thru taurine, and the other is thru the manganese based UGT glucurondination  pathway.  both of these substances get used up over time while taking any drug... and thats why it takes accutane 4-6 months to work.  it needs to overrun your bodies own ability to detoxify itself.   some people have more ability than others (genetic or diet based)  to keep up.  these are the people that need multiple courses of accutane to work imo.

taurine also fits a lot of the side effects...even acting like a natural SSRI(GABA promoter)... that was an interesting post about SSRI and collagen btw. 

 

walden rev... btw my hair shedding has been reduced by about 90%.   i have a full head of hair.... but if i were to run my hands thru my hair, i would notice so many broken hairs... it was ridiculous.   this could be the healing of fibrosis. this would also be the same healing that is taking place in your liver.  i dont know about you, but thinking back now... one of the weirder side effects i went thru while on the drug.... is that i lost all of the hair around my ankles/lower leg, and they never came back.  will be interesting to see if they start coming back.

 

its funny, 20 years ago i went to a holistic doctor and told her all of my side effects, and she prescribed p-5-p.   i thought she didnt even hear me and was an idiot.  never took it.    turns out she mightve been right all along in helping me.  in that, p-5-p is the main nutrient your body needs, in addition to sulfur based foods,  to make taurine naturally.

Quote
0
(@Anonymous)

Posted : 12/12/2015 12:46 pm

7 minutes ago, tryingtohelp2014 said:

 

How much taurine are you taking?

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MemberMember
76
(@yetanotheraccutanevictim)

Posted : 12/12/2015 1:05 pm

@FchawkHow are you ingesting that many IUs of vit A? Is it supplemental, from liver, cod liver oil, or what?

 

Also, that paper showed that it would take 1mil IU retinolper day to mimic the side effects of taking 1-2mg/kg per day of accutane. However, how many IUs of synthetic vitamin A are in the actual accutane pills? Does anyone know the conversion of isotretinoin mg to IUs of vitamin A?

I took 80mg of generic accutane (Claravis) for 4 months and 40mg for 1 month. In total, it was 10,800 milligrams of accutane. My weight at the time was 120 pounds or 55kg.

 

@sam1w2eTaking 3-5g per day of taurine is a good amount. Make sure it's a high quality supp brand. I also recommend people take glycine, taurine, and phosphatidyl choline together withvitamin C to have maximum benefit to bile production. There is a rectal supplement known as Glytamins that people should try out. It bypasses everything and goes straight to the liver via the portal vein. Looks very effective.

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MemberMember
42
(@relentless-to-find-tane-cure)

Posted : 12/12/2015 2:23 pm

5 hours ago, AlanTookAccutaneWow said:

 You keep taking your supplements and studying how you think the body works fictionally. *facepalm*

We are not studying fiction. I am studying biology, chemistry and physics to understand how the body works.

A supplement can provide ingredients that are nearly as crucial to the body as oxygen is. 
All food turns to electrons. We dont have a protein or carbohydrate transport chain in our body, we have an electron transport chain that makes ATP from electrons, the electrons come from food. 

This is not fiction. You can be deficient in taurine even though you eat meat. And maybe supplementing taurine can help fix something.

Its like saying you should build a house without a hammer and nails or any other tools. Supplements and foods, lifestyle stuff like fasting are all tools. Use all the tools that work FOR YOU and dont use the ones that doesnt work. But if it doesnt work for you it can work for someone else.

You go sit in the sun and stop eating and you'll be dead in a few weeks. Fasting is just a tool, and it has a great benefits if used sparingly. Do intermittent fasting if you love fasting so much. I get hypoglycemic so id rather do ketosis than fasting. 

And i already get sun :) I already have done fasting on occassion for 2 years. Ive fasted for 1 week. Ive done juice fasting, ketogenic fasting. Ive done cold thermogenesis, sauna, sun, fake sun and ive also tried a bunch of supps, foods and other things.

Fasting is really good but you are severely limiting yourself by sticking to "fasting, sun and complaining and saying things like GIVE ME SOME BOOZE!!!1"

Make a effort to help people here or fk off dude. People have already reported your posts countless times and a moderator has stated in the thread that the off topic bullshit that people like you type in here has to stop.

 

Start reading about supps on examine.com or pubmed, and tell me they dont work. Its like saying accutane doesnt work for acne.. And alcohol doesnt work for being drunk. All you need is a day of fasting and you will be drunk? 
Fasting is good because it promotes autophagy but it can also seriously harm you in the longrun. 

3 minutes ago, Relentless1k said:
3 hours ago, AlanTookAccutaneWow said:

Do NOT take antidepressants. You've been warned! They will mess with more chemicals in your brain and also generally leave you feeling more numb and unhuman in the end. This goes for most prescription drugs (as we've learned).

 

Do NOT take any pills. 

 

You can with enough effort (shopping: knowing people, and of course hunting gathering skills) get every amino acid, vitamin, variety, that you need to wake up feeling refreshed, each day, and dealing with whatever comes your way on a totally awesome energetic level. 

 

So what if i go and hunt some animals and put them in pills, or make some veggies and put them in pills. Will this harm me?
Pills do not equal bad. Allthough synthetic pharma bullshit is dangerous. I still dont think anti depressants are a no no if natural ways failed at restoring your mental health. Some people actually do get their life turned around from anti depressants..

Quote
MemberMember
42
(@relentless-to-find-tane-cure)

Posted : 12/12/2015 2:42 pm

2 hours ago, tryingtohelp2014 said:

'

Listen, i believe that taurine is the start of a long reaction. One of the main reactions is the ability to absorb fats again. this will naturally include Vitamin A D E K. so i would stop all vitamin A supplementation while on taurine. thats my opinion. i could totally be wrong about that. you wont need to take any extra fat soluable vitamins... your body will naturally start to absorb these atits own pace. you could be hampering your bodies detoxification process by adding something else toget rid of. i think the taurine needs time. so everyone asking me if its ok to take extra vitamin D... no.

 

but i do believe everything starts with this step. by upregulating the PI3K/AKT pathways, we will naturally kick the upregulated FOXO1 out of the nucleus... ending a lot of our side effects. now this includes that whole list of supplements....and a lot of us have already gravitated towards these compounds for different reasons anyway... taurine creatine DHA ,bcaas, colostrum, tudca TMG etc etc.

 

the one reason i focus on taurine is... out of all of the PI3K/AKT promoters, it also has the proven vitamin A conjugation aspect. it is specifically listed as a treatment for hypervitaminosis A. this is also the reason i focused on manganese. accutane is only conjugated in one of two ways. one is thru taurine, and the other is thru the manganese based UGT glucurondination pathway. both of these substances get used up over time while taking any drug... and thats why it takes accutane 4-6 months to work. it needs to overrun your bodies own ability to detoxify itself. some people have more ability than others (genetic or diet based) to keep up. these are the people that need multiple courses ofaccutane to work imo.

taurine also fits a lot of the side effects...even acting like a natural SSRI(GABA promoter)... that was an interesting post about SSRI and collagen btw.

 

walden rev... btw my hair shedding has been reduced by about 90%. i have a full head of hair.... but if i were to run my hands thru my hair, i would notice so many broken hairs... it was ridiculous. this could be the healing of fibrosis. this would also be the same healing that is taking place in your liver. i dont know about you, but thinking back now... one of the weirder side effects i went thru while on the drug.... is that i lost all of the hair around my ankles/lower leg, and they never came back. will be interesting to see if they start coming back.

 

its funny, 20 years ago i went to a holistic doctor and told her all of my side effects, and she prescribed p-5-p. i thought she didnt even hear me and was an idiot. never took it. turns out she mightve been right all along in helping me.in that, p-5-p is the main nutrient your body needs,in addition to sulfur based foods, to make taurine naturally.

 

You my friend are onto the most useful info ive seen here.

Keep doing your thing! I believe we can figure out a solution together (me, you and all the others in here)
Its funny how all these nutrients that will likely help us by doing this and that in the body also helps pretty much every other system in the body. We do get enough BCAA if we eat seafood/meat tho. But i take BCAA personally because my digestion sucks after accutane, still working on reversing that.

The whole protein folding stack fits with our findings as well (taurine, creatine, beta alanine, trehalose, TMG and glycine)
We need more glycine after accutane. Likely also SAM-e. At least according to the studies accutane impairs that. (I believe through fast conversion of SAM to SAH and something that metabolises glycine or gets rid of it is upregulated or downregulated which increases the need for it to do its basic jobs)

 

P-5-P and the other active b vitamins are crucial, they have been so powerful in me that i have to take really low doses because the effects are so strong that it gets me extra anxious (the effects are really good and signs of healing, but too much at once)

"Many reasons for fat malabsorption and it could be related to deficient taurine and/or phosphatidylcholine a sign of low methylation and insufficient sulfur in the diet." - Dr Ben Lynch

 

 

DHA is crucial to all people as well, obviously.

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MemberMember
960
(@tryingtohelp2014)

Posted : 12/12/2015 2:44 pm

54 minutes ago, Relentless1k said:

We are not studying fiction. I am studying biology, chemistry and physics to understand how the body works.

A supplement can provide ingredients that are nearly as crucial to the body as oxygen is. 
All food turns to electrons. We dont have a protein or carbohydrate transport chain in our body, we have an electron transport chain that makes ATP from electrons, the electrons come from food.

You go sit in the sun and stop eating and you'll be dead in a few weeks. Fasting is just a tool, and it has a great benefits if used sparingly. Do intermittent fasting if you love fasting so much. I get hypoglycemic so id rather do ketosis than fasting. 

And i already get sun :) I already have done fasting on occassion for 2 years. Ive fasted for 1 week. Ive done juice fasting, ketogenic fasting. Ive done cold thermogenesis, sauna, sun, fake sun and ive also tried a bunch of supps, foods and other things.

Fasting is really good but you are severely limiting yourself by sticking to "fasting, sun and complaining and saying things like GIVE ME SOME BOOZE!!!1"

Make a effort to help people here or fk off dude. People have already reported your posts countless times and a moderator has stated in the thread that the off topic bullshit that people like you type in here has to stop

 

 

heres some simple math on eating healthy and supplementation .

 

the body contains 70 grams (70,000 mg)  of taurine

the average diet consists of 58 mg of taurine.

how long would it take you (potentially being completely depleted mind you) to build your stores back up by eating raw and healthy?!

plus you would have to subtract your bodies daily needs on top of this.  what if the body needs 50mg of that a day just to function( so you dont go blind, or have constant irregular heartbeats etc) , much less build up any type of reserve to have extra amounts available for detoxification. 

so under that scenario, you would be adding a net +8mg a day total to your reserve of a potential 70,000mg deficieny.

that would be 8 x 365 x 24 = 70000mg

24 YEARS it would take you

 

eating healthy would take an eternity to fix any type of a major problem, which we could all agree we have.

Remember  my theory is:  accutane could shut off our bodies own ability to make taurine naturally by upregulating GNMT, basically destroying the methionine used to make taurine.  And if this GNMT enzyme stays upregulated even after stopping this drug (which has been proven), our homeostatic ability to maintain a proper balance would permanently be shut off.   also by depleting  our bodies initial pool size to conjugate months of accutane ingestion.

 

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MemberMember
42
(@relentless-to-find-tane-cure)

Posted : 12/12/2015 2:48 pm

1 hour ago, yetanotheraccutanevictim said:

\

@sam1w2eTaking 3-5g per day of taurine is a good amount. Make sure it's a high quality supp brand. I also recommend people take glycine, taurine, and phosphatidyl choline together withvitamin C to have maximum benefit to bile production. There is a rectal supplement known as Glytamins that people should try out. It bypasses everything and goes straight to the liver via the portal vein. Looks very effective.

Stuff goes directly to the liver from the stomach as well though, not a lot of stuff actually gets altered by stomach acid.

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(@relentless-to-find-tane-cure)

Posted : 12/12/2015 3:28 pm

"Theres only one food that matters, and im not kidding when i say that. Its DHA" - Dr. Jack Kruse

You guys are at least correct that seafood is good (and ive never said its not), but food is not that important as long as you get enough electrons to make enough ATP where you sustain life. Nutrients are super important but they dont HAVE TO come from food. Kruse doesnt recommend a lot of supplements tho, but he does support supplementing all the nutrients and instead only eating foods that actually matter, which turns out is seafood and other good fat sources. And enough glucose that your body can operate on. But again you could supplement glucose

So in a nutshell a simplified really healthy diet would be this:

Seafood (high quality wild caught)

Greens

Nutrients, glucose and the rest of your fat can come from supplements (Oils and butter are supplements, they are not whole foods)

Just get enough DHA/EPA and protein from seafood, enough fiber and all the beneficial plant chemicals from vegetables. (Eat a ton of them and all the different colors)

Of course have some fruit, especially berries. Get the rest of your fats from black cumin seed oil, olive oil, coconut and palm oil, MCT oil, grass fed butter. More glucose and starch can be supplemented, or eaten. Up to you. Best food source is likely purple sweet potatoes. Regular sweet potatoes are good too.

All grains and legumes are toxic. Nuts and seeds can be good but not if you have bad digestion + they can easily overload you with too much omega 6.

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(@yetanotheraccutanevictim)

Posted : 12/12/2015 5:23 pm

Be aware that sweet potatoes are incredibly high in oxalates and led to my demise. Not all people have problems with them but just putting that out there. They cause muscle and joint pain.

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(@relentless-to-find-tane-cure)

Posted : 12/12/2015 5:29 pm

You can pressure cook them or take calcium to bind to oxalates?Pressure cooker also kills any lectins that are present

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(@tryingtohelp2014)

Posted : 12/12/2015 5:31 pm

probably not the oxalates, probably the 800% vitamin A giving u pains

 

http://nutritiondata.self.com/facts/vegetables-and-vegetable-products/2667/2

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(@yetanotheraccutanevictim)

Posted : 12/12/2015 5:41 pm

10 minutes ago, tryingtohelp2014 said:

probably not the oxalates, probably the 800% vitamin A giving u pains

 

http://nutritiondata.self.com/facts/vegetables-and-vegetable-products/2667/2

Well it's actually pro-vitamin A. Plants don't have vitamin A. And it's not the vitamins in it causing my pain. It actually is oxalates, unfortunately. They built up during and after I took accutane. Probably due to the increased intestinal permeability and the antibiotics wiping out my oxalate degrading bacteria. I literally excrete oxalates in my stool now. It's crazy. The more nutrients I get, the faster I excrete the oxalates. It's called oxalate dumping. I get all tingly and shaky when "dumping." If I'm all tingly and twitchy in the afternoon one day, I know that the next morning I will excrete oxalates in my stool. Happens like clockwork. I'm tempted to post some pictures of my oxalate stools for all to see. Maybe it's best if you take my word :)

 

I'm thinking about purchasing EDTA in suppository form to chelate the oxalates. Not sure yet. It's like $90 per month.. I'm tired of trying supplements that end up in failure. We'll see though. Maybe that'll be my x-mas gift...

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(@alantookaccutanewow)

Posted : 12/12/2015 6:47 pm

]

5 hours ago, Relentless1k said:

We are not studying fiction. I am studying biology, chemistry and physics to understand how the body works.

A supplement can provide ingredients that are nearly as crucial to the body as oxygen is. 
All food turns to electrons. We dont have a protein or carbohydrate transport chain in our body, we have an electron transport chain that makes ATP from electrons, the electrons come from food. 

This is not fiction. You can be deficient in taurine even though you eat meat. And maybe supplementing taurine can help fix something.

Its like saying you should build a house without a hammer and nails or any other tools. Supplements and foods, lifestyle stuff like fasting are all tools. Use all the tools that work FOR YOU and dont use the ones that doesnt work. But if it doesnt work for you it can work for someone else.

You go sit in the sun and stop eating and you'll be dead in a few weeks. Fasting is just a tool, and it has a great benefits if used sparingly. Do intermittent fasting if you love fasting so much. I get hypoglycemic so id rather do ketosis than fasting. 

And i already get sun :) I already have done fasting on occassion for 2 years. Ive fasted for 1 week. Ive done juice fasting, ketogenic fasting. Ive done cold thermogenesis, sauna, sun, fake sun and ive also tried a bunch of supps, foods and other things.

Fasting is really good but you are severely limiting yourself by sticking to "fasting, sun and complaining and saying things like GIVE ME SOME BOOZE!!!1"

Make a effort to help people here or fk off dude. People have already reported your posts countless times and a moderator has stated in the thread that the off topic bullshit that people like you type in here has to stop.

 

Start reading about supps on examine.com or pubmed, and tell me they dont work. Its like saying accutane doesnt work for acne.. And alcohol doesnt work for being drunk. All you need is a day of fasting and you will be drunk? 
Fasting is good because it promotes autophagy but it can also seriously harm you in the longrun. 

So what if i go and hunt some animals and put them in pills, or make some veggies and put them in pills. Will this harm me?
Pills do not equal bad. Allthough synthetic pharma bullshit is dangerous. I still dont think anti depressants are a no no if natural ways failed at restoring your mental health. Some people actually do get their life turned around from anti depressants..

 

 

ALL you have done here is argue with me, to where I feel like I am basically having a conversation with myself. Food does not turn to electrons, (Who is teaching you kids this funny stuff, although ill admit it does SOUND believable). Food is digested and either used or stored as energy. A protein carbohydrate transport chain? Yeah, Ok! Take a look at your muffler bearings while were "on topic" here. 

Its it my sense of humor that pisses you off lol?

Oh im so sorry that through my efforts of trying to bring something to the table, I have not done that at all. Yeah RIGHT, You know that I have provided my heart on this, and there is nothing wrong with that, ya grinch. 

Id be dead if i didn't eat in the sun for two weeks? MAYBE. Thanks for the pointer?

NOOO! I am not going to read about supplements. Face palm number 3! I have taken them all, I know they just screw us humans up in the long run. I guess... if you want to take them and then throw something else off, for the rest of your life :huh:

 

Your point fired back at itself. Accutane works for acne? of course it does! But HERES the point: were the side effects worth it? Hell no!  These synthetics only cover up problems (And they charge so much for these supplements).

 

Give me some booze!

Who the hell puts animals or veggies in pills? Why would you. Hello, the beauty is NOT in the pill. 

Fasting does NOT harm you in the long run, You should probably rest more when you fast, and be aware that life will go into a sort of "Slow motion" if you will, there is not a medical definition or consequence to this, its just how it is!

Ok, well, then take your supplements if you think they are food. You can report me all you want. I REALLY don't care. I am only here to tell the truth. You're wasting your time studying biology and all this crap dude, its ALL fiction. Everything you learn in class is completely useless crap. More information for you, when you get out of school, you can spend the next ten years simply paying off your debts for whatever bullshit they taught you. Antidepressants do NOT turn lives around, lol, they make people that already are unhealthy (American diet, hello?) locked into misery. 

 

I don't know what else to tell you but Im not going to argue, again, about these stupid theories on what vitamin A does to FOX1 and Taurine up regulation. Its ALL MADE UP! Dude! You could study it for the next 1000 years and you'd still REALLY, Have figured out nothing. Doctors don't even know how serotonin works (yet). Why do you think everything has side effects, because its just craaaaaap. 

Why would you type this made up crap, while attacking me? I already said, leave me to be me. If you continue to quote my posts with this sort of masked hatred, I will CONTINUE to treat it just as when anyone else talks to me. So don't pick at me and I won't pick at you. We should be able to keep the thread going JUST FINE.

Take your brainwash somewhere else please.

 

 

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(@Anonymous)

Posted : 12/12/2015 7:23 pm

32 minutes ago, AlanTookAccutaneWow said:

I am only here to tell the truth. You're wasting your time studying biology and all this crap dude, its ALL fiction.

 

 

Reaction-Pic---You-gotta-be-kidding-me.jpg

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(@alantookaccutanewow)

Posted : 12/12/2015 7:32 pm

I think that its funny how many people believe that through studying the human body, they are going to figure out something amazing. We aren't meant to be able to hack the body in ANY way without consequences.

 

Do you think they studied in depth about formation ofacne when they "invented" a drug like accutane? Nah, they just found that HEY THIS STUFF WE CREATED WORKS FOR ACNE, MAKE MORE!

 

There is no way to classify anything, we can make up silly names for what we see under the microscope but really we have no idea what is happening on even the first level. I know that YOU have been TOLD, what it is, but this is just what THEY think it is. Which really still means, no one knows, LOL!The point is, don't bother, but DO, think about what you put into your mouth! We can play the supplement game all day but I just don't want to see anyone waste any more thought on that when we could be experimenting with, well, much funner things.

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(@guitarman01)

Posted : 12/12/2015 10:35 pm

I would be careful on supplementing vitamin A. I tried that awhile back at maybe up to 75k iu once per day for a short amount of time. The thing is you dont notice some chronic effects until its too late. this was years ago i did this, and one side effect to this day is that It created many more fine lines on my hands, and calluses right below my fingers that havent gone away since. also gave me more eye floaters, and joint pain in one of my knees . the placebo effect can be strong I know, but i dont think massive doses of vitamin a is the answer.

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(@fchawk)

Posted : 12/13/2015 12:48 am

8 hours ago, tryingtohelp2014 said:

probably not the oxalates, probably the 800% vitamin A giving u pains

 

http://nutritiondata.self.com/facts/vegetables-and-vegetable-products/2667/2

 

You can't get vitamin A toxicity from Beta-Carotene, your body will stop turning it into vitamin A (which is why I don't have it, I want to overwhelm it a little ;)

 

13 hours ago, tryingtohelp2014 said:

Listen, i believe that taurine is the start of a long reaction.  One of the main  reactions is the ability to absorb fats again.  this will naturally include Vitamin A D E K.   so i would stop all vitamin A supplementation while on taurine.  thats my opinion. i could totally be wrong about that.   you wont need to take any extra fat soluable vitamins... your body will naturally start to absorb these at its own pace.  you could be hampering your bodies detoxification process by adding something else to get rid of.   i think the taurine needs time.  so everyone asking me if its ok to take extra vitamin D... no.  

 

but i do believe everything starts with this step.  by upregulating the PI3K/AKT pathways, we will naturally kick the upregulated FOXO1 out of the nucleus... ending a lot of our side effects.  now this includes that whole list of supplements....and a lot of us have already gravitated towards these compounds for different reasons anyway... taurine creatine DHA ,bcaas, colostrum, tudca TMG etc etc.

Interesting... I agree with pretty much everything here, taking taurine creatine DHA ,bcaas, colostrum, tudca TMG etc. will improve the health of anyone suffering symptoms. I think while these may bring you to a baseline much closer to the norm of the general populace, so if you took it for a few months you would have few symptoms, and even if you stopped your symptoms that reappeared would be much reduced. However I think they would still reappear (Hope I'm wrong!), and I think the way to take that last step will be to address the underlying issue of the retinoid imbalance that caused all this, and take Vitamin A, along with taurine etc for a few months, which I hope would allow us to get of everything once and for all

Keep in mind that that means I am agreeing with the first few months TTH2014's treatment, and I will have continued to update in a few months when it becomes clear what the results of my treatment are, so you can choose which route to take after that when we have all the facts on the table :) 

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