Hi all,

- has anyone considered that the underlying issue is an overactive sympathetic nervous system?

Hi all,

- has anyone considered that the underlying issue is an overactive sympathetic nervous system?

It looks veryplausible...The target organs of the SNS being most of what is affected in us: eye, heart, stomach, liver, intestine, pancreas, adrenals, gonads. I shift positions so often. I really can't decide whether this is allneurologically driven, hormonal driven, or digestive. Butthen when Iconsider the fact that our cells do not replicate as they used to (wounds heal slower, hair brittle and dry, gingivitis and halitosis, very difficultto increase muscle mass, arthritis of the joints). The changes have to beon a genetic cellular level which is why the side effects are plenty and encompass the entire body. So, yes in a sense I think it's neurological, hormonal, internal, all that and then some if you consider ourselves to be simply statedaffected on a Cellular level. Maybe Nathan was right inproposing that our telomere's were shortened. Skin cells, to internal gut cells, to brain cells...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC34517/
Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation
(2001)

Hi all,

- has anyone considered that the underlying issue is an overactive sympathetic nervous system?

It looks veryplausible...The target organs of the SNS being most of what is affected in us: eye, heart, stomach, liver, intestine, pancreas, adrenals, gonads. I shift positions so often. I really can't decide whether this is allneurologically driven, hormonal driven, or digestive. Butthen when Iconsider the fact that our cells do not replicate as they used to (wounds heal slower, hair brittle and dry, gingivitis and halitosis, very difficultto increase muscle mass, arthritis of the joints). The changes have to beon a genetic cellular level which is why the side effects are plenty and encompass the entire body. So, yes in a sense I think it's neurological, hormonal, internal, all that and then some if you consider ourselves to be simply statedaffected on a Cellular level. Maybe Nathan was right inproposing that our telomere's were shortened. Skin cells, to internal gut cells, to brain cells...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC34517/
Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation
(2001)

any ways to halt telomere shortening other than the usual-- anti-oxidants, healthy living, and anti aging protocols? I honestly think this has something to do with it as well.

Hi all,

I had an interesting idea recently after again noticing my symptoms seem better after a night of drinking/taking nervous system depressants- has anyone considered that the underlying issue is an overactive sympathetic nervous system? Symptoms of this include: chronic fatigue, exercise intolerance, food sensitivities, anxiety, depression, numbness/tingling, irritability, anger, heart pounding or arrhythmia, adrenal fatigue, gastrointestinal disorders, sweating, impotency, candida, high blood pressure/heart disease, and the list goes on. This pretty much covers every one of our symptoms.

I sent a message to my doctor about potential tests/treatments and am waiting to hear back, just thought I'd throw this idea out there. Hope everyone is doing well (as can be expected).

Cheers

EDIT: The more I read about autonomic neuropathy/dysautonomia the more it fits the bill as a progressive disease that accounts for all of our symptoms. Unfortunately the prognosis is not always great, but I am going to be in communication with my doctor and will report back any info I find. If anyone else has any insight on this, please feel free to share in the meantime.

Hi all,

I had an interesting idea recently after again noticing my symptoms seem better after a night of drinking/taking nervous system depressants- has anyone considered that the underlying issue is an overactive sympathetic nervous system? Symptoms of this include: chronic fatigue, exercise intolerance, food sensitivities, anxiety, depression, numbness/tingling, irritability, anger, heart pounding or arrhythmia, adrenal fatigue, gastrointestinal disorders, sweating, impotency, candida, high blood pressure/heart disease, and the list goes on. This pretty much covers every one of our symptoms.

I sent a message to my doctor about potential tests/treatments and am waiting to hear back, just thought I'd throw this idea out there. Hope everyone is doing well (as can be expected).

Cheers

EDIT: The more I read about autonomic neuropathy/dysautonomia the more it fits the bill as a progressive disease that accounts for all of our symptoms. Unfortunately the prognosis is not always great, but I am going to be in communication with my doctor and will report back any info I find. If anyone else has any insight on this, please feel free to share in the meantime.

I have also noticed this over the years. I feel more "normal" and my sex drive and erection fullness are greatly improved after a night of drinking.

Or maybe I'm just saying this because I feel smarter than I did before accutane and I'm ananomaly. Maybe I've just been smoking too much. We'll never know..

If you're suggesting that Isotretinoin made you smarter, that's unlikely. If anything, it makes you dumber since it's known to

cause 21% decreased brain metabolism in the orbitofrontal cortex

. There aren't any benefit to the brain during/after a course of Isotretinoin and it's all net negative. How much badly Isotretinoin affects the brain depends on the individual. So most likely, you got smarter/wiser because of aging.

On 10/26/2015 at 11:36 PM, Modeaa said:

lolaccutane

from going over your posts with my not perfect english i got that you are trying to repair what might be called leaky gut/intestinal permeability + killing candida/yeast/bad microbes.

 

can you please mention about the part of killing the bad candida/yeast/bad microbes about how you are doing it- like what are you taking etc.

 

 

for the leaky gut you just take colostrum and and collegen and gelatin? anything else? thanks.

 

 

 

 

 

.

 

 

 

 

My last stool test (7/21/14) showed that my "Yeast/Fungi" was at >100000 pg DNA/g, which is the highestvalue. I was given some sort of tincture (Biocide something), butnever tested my stoolagain to see if it worked (cost me about $500). I didn't notice a difference. I just ordered these https://drbenkim.com/sunshop/index.php?l=product_detail&p=123 and am expecting to start taking this week. Keep in mind I have been taking (and rotating) probiotics foryears and still got these high yeast results.

My last stool test (7/21/14) showed that my "Yeast/Fungi" was at >100000 pg DNA/g, which is the highestvalue. I was given some sort of tincture (Biocide something), butnever tested my stoolagain to see if it worked (cost me about $500). I didn't notice a difference. I just ordered these https://drbenkim.com/sunshop/index.php?l=product_detail&p=123 and am expecting to start taking this week. Keep in mind I have been taking (and rotating) probiotics foryears and still got these high yeast results.

Do you mind sharing which specific stool test you got? I've gotten both Genova's and BioHealth's comprehensive stool analyses done but detected no yeast overgrowth. I have fibromyalgia and have always been curious about fungal overgrowth but cannot find any whatsoever. Also, I've been on many infection killing protocols with no benefit. I should also mention that I appear to have a lot of mold growing in my house. I don't seem to have any inflammation, though. Not sure if I could have CIRS.

One thing I've noticed is that I seem to beloaded with oxalates. It seems like I excrete oxalates in my stool whenever I eat a very low oxalate diet and am supplementing with about 500 mg of B6 (both inactive and P5P forms) along with magnesium. I've gotten an organic acids urine test which showed high amounts of oxalates being excreted in my urine indicating nutritional hyperoxaluria. I've never had any kidney stones but I'm pretty sure oxalates shouldn't be entering my bloodstream at that rate.

For 2 years (including my 5 month accutane course) I ate an extremely high oxalate diet (loads of sweet potatoes, plantains, almonds, spinach, etc..) and slowly developed chronic, systemic pain. Still not sure if this is my main issue but it's looking very likely. Others with chronic pain may want to look into this. My muscles hurt primarilybut my joints hurt as well. Poor circulation is also another major concern I have. Look up the Low Oxalate group on Yahoo for more detailed information. And maybe there's a link between me having oxalate toxicity and mold exposure..

lolaccutane

from going over your posts with my not perfect english i got that you are trying to repair what might be called leaky gut/intestinal permeability + killing candida/yeast/bad microbes.

can you please mention about the part of killing the bad candida/yeast/bad microbes about how you are doing it- like what are you taking etc.

for the leaky gut you just take colostrum and and collegen and gelatin? anything else? thanks.

My last stool test (7/21/14) showed that my "Yeast/Fungi" was at >100000 pg DNA/g, which is the highestvalue. I was given some sort of tincture (Biocide something), butnever tested my stoolagain to see if it worked (cost me about $500). I didn't notice a difference. I just ordered these https://drbenkim.com/sunshop/index.php?l=product_detail&p=123 and am expecting to start taking this week. Keep in mind I have been taking (and rotating) probiotics foryears and still got these high yeast results.

Do you mind sharing which specific stool test you got? I've gotten both Genova's and BioHealth's comprehensive stool analyses done but detected no yeast overgrowth. I have fibromyalgia and have always been curious about fungal overgrowth but cannot find any whatsoever. Also, I've been on many infection killing protocols with no benefit. I should also mention that I appear to have a lot of mold growing in my house. I don't seem to have any inflammation, though. Not sure if I could have CIRS.

One thing I've noticed is that I seem to beloaded with oxalates. It seems like I excrete oxalates in my stool whenever I eat a very low oxalate diet and am supplementing with about 500 mg of B6 (both inactive and P5P forms) along with magnesium. I've gotten an organic acids urine test which showed high amounts of oxalates being excreted in my urine indicating nutritional hyperoxaluria. I've never had any kidney stones but I'm pretty sure oxalates shouldn't be entering my bloodstream at that rate.

For 2 years (including my 5 month accutane course) I ate an extremely high oxalate diet (loads of sweet potatoes, plantains, almonds, spinach, etc..) and slowly developed chronic, systemic pain. Still not sure if this is my main issue but it's looking very likely. Others with chronic pain may want to look into this. My muscles hurt primarilybut my joints hurt as well. Poor circulation is also another major concern I have. Look up the Low Oxalate group on Yahoo for more detailed information. And maybe there's a link between me having oxalate toxicity and mold exposure..

 

Please take vitamin k2 if you're taking vitamin d. I got what felt like stones (never confirmed) but that feeling cleared up after a week on life extension brand super k complex. I will get a liquid supplement when I finish the bottle. I'm trying to pop less pills. I took Lectin Lock for a while every time I ate grains or tomatoes or white potatoes and my gut felt a LOT better, but I don't want to carry around 20 pills when I eat. I already take loads of betaine HCL and other enzymes and get enough looks as it is. I stopped taking it and healed my gut and they still bother me, but I don't care, if a pretty girl wants to get pizza with me, I'm going. I do react MUCH less though, after lots of interventions (probiotics, fermented foods, colostrum, fish/krill oil, dietary turmeric, etc). There's a similar supplement called ox-absorb if you wanna take a look. Kinda mixed reviews tho. I believe that fixing your immune system, gut, and brain will result in you being able to handle any food at all (not that you'd want to eat it all the time). You may have to avoid the stuff you react to while healing, but usually you're able to add it back in. Sourdough just tastes too good to not eat.

 

I've been reading up on Jack Kruse. Dude's batshit crazy but I think he's on to something. Lots of seafood for that DHA, iodine, selenium and 'electrons' to build the brain. Maybe there was something to that guy on this thread years ago that only ate shrimp and rice and said he felt good? Avoid EMFs and please put the wifi off at night. My sleep score goes down 10 points on the sleep cycle app if the wifi in the room next to mine is on. This is repeatable. I try to only use ethernet straight from my modem without a router, but this isn't always possible. I think it's a good idea to move in that direction. According to Kruse, EMFs cause calcium channel efflux and messes up cell signaling. Look into cold thermogenesis, I used this successfully to help in losing weight but I was only using a vest, not a cold bath, so I probably wasn't getting the full benefit. This isn't necessary but it helps. I'm trying to drink better water. I've been drinking spring water almost exclusively and god damn is it expensive. RO water seems like it makes sense with trace mineral drops added in. What water are you guys drinking?

 

Vitamin d (preferably from the sun for sulfated vitamin d, have sulfur rich foods and cholesterol), vitamin k2, vitamin a, and magnesium all work on calcium metabolism. I remember reading something about beta carotene only forming full vitamin A at nighttime when melatonin is at a certain level. Circadian biology is tied to vitamin a metabolism. Keep to a circadian rhythm. I wear blue blocking glasses at night (only if I'm home lol), use f.lux on my laptop, and sleep in absolute darkness. Even a little bit of light disrupts melatonin signalling and certain pathways that regenerate your body don't turn on. When I wake up I try to go in the sun for at least a couple minutes to set my clock. Your body needs to know if it's day or night. According to Kruse, every cell has a clock gene that responds to circadian signals. If you can wake with the sun and sleep a couple hours after the sun sets, that optimal. Unfortunately, being a musician, this is near impossible, but I'm hoping that clear cycles of full exposure to sun light and absolute darkness will take me in that direction.

 

I personally think it's bullshit that humans aren't meant to eat grains or junk food every now and then. If our immune system, gut, and brain is working, I should be able to walk into a moldy building and eat pizza and be fine. Not that I would do that regularly, but my goal is to be in perfect health, I don't even care about accutane 'side effects' anymore. I can't determine what I felt like before accutane.

 

And this is a friendly reminder to keep knocking down your goals, other than health. Social, business, work, love. Get better everyday. Keep growing. And just spew out knowledge. Throw breadcrumbs in the air and the right people WILL catch on. You never know what makes someone tick. You just might be surprised by the friends you make...

 

Ialso fast occasionally and take powdered charcoal to bind anything that may be in the gut. Long term I think this will really help. I use upgraded coconut charcoal. This also binds to mycotoxins (mold toxins)

Hey guys, 
i am so happy that i found this Forum! 3 years ago i took Roaccutan (isotetrinoin), but Not Long and low dose. I had big side-Effects and stopped taking Roaccutan
My main Problem is the Hyperhidrose (extreme sweating)
i was at 10 Different doctors und tried Many Many Medications: 
somodren
vagantin 
opipramol 
sage tea 
a lot Minerals and Vitamines 
and at Last Zyprexa (olanzapin), which helped me to stop sweating for 1-2 months, bug slowly the Hyperhidrose comes back!! 

I come from Germany and my english isnt realy good, please Be Patient 
i Would prefer to read every page in this Thread but my english is to Bad 

Does anybody had the Same Problem (Hyperhidrose) After taking Roaccutan and can help me??? Any Medications/drugs??
does anybody Know what is going on with my Body??

please help me   
i cant and won't live with this Problem  

Hope anybody reply 

On 10/28/2015 at 12:28 PM, tryingtohelp2014 said:

On 10/28/2015 at 6:54 AM, BillionProblems said:

Hey guys,
i am so happy that i found this Forum! 3 years ago i took Roaccutan (isotetrinoin), but Not Long and low dose. I had big side-Effects and stopped taking Roaccutan
My main Problem is the Hyperhidrose (extreme sweating) [Edited image out]
i was at 10 Different doctors und tried Many Many Medications:
somodren
vagantin
opipramol
sage tea
a lot Minerals and Vitamines
and at Last Zyprexa (olanzapin), which helped me to stop sweating for 1-2 months, bug slowly the Hyperhidrose comes back!!

I come from Germany and my english isnt realy good, please Be Patient
i Would prefer to read every page in this Thread but my english is to Bad

Does anybody had the Same Problem (Hyperhidrose) After taking Roaccutan and can help me??? Any Medications/drugs??
does anybody Know what is going on with my Body??

please help me [Edited image out][Edited image out]
i cant and won't live with this Problem [Edited image out]

Hope anybody reply

you have whats called TEWL. basically it confirms your skin is damaged from accutane, and cant hold onto the water. you literally feel dried out. evening primrose oil (GLA)is the only thing that i come up with.

Hey guys, 
i am so happy that i found this Forum! 3 years ago i took Roaccutan (isotetrinoin), but Not Long and low dose. I had big side-Effects and stopped taking Roaccutan
My main Problem is the Hyperhidrose (extreme sweating)
i was at 10 Different doctors und tried Many Many Medications: 
somodren
vagantin 
opipramol 
sage tea 
a lot Minerals and Vitamines 
and at Last Zyprexa (olanzapin), which helped me to stop sweating for 1-2 months, bug slowly the Hyperhidrose comes back!! 

I come from Germany and my english isnt realy good, please Be Patient 
i Would prefer to read every page in this Thread but my english is to Bad 

Does anybody had the Same Problem (Hyperhidrose) After taking Roaccutan and can help me??? Any Medications/drugs??
does anybody Know what is going on with my Body??

please help me   
i cant and won't live with this Problem  

Hope anybody reply 

you have whats called TEWL.  basically it confirms your skin is damaged from accutane, and cant hold onto the water.  you literally feel dried out.  evening primrose oil (GLA) is the only thing that i come up with.

On 10/28/2015 at 1:17 PM, BillionProblems said:

On 10/28/2015 at 12:28 PM, tryingtohelp2014 said:

On 10/28/2015 at 6:54 AM, BillionProblems said:

Hey guys, 
i am so happy that i found this Forum! 3 years ago i took Roaccutan (isotetrinoin), but Not Long and low dose. I had big side-Effects and stopped taking Roaccutan
My main Problem is the Hyperhidrose (extreme sweating) [Edited lmage out]
i was at 10 Different doctors und tried Many Many Medications: 
somodren
vagantin 
opipramol 
sage tea 
a lot Minerals and Vitamines 
and at Last Zyprexa (olanzapin), which helped me to stop sweating for 1-2 months, bug slowly the Hyperhidrose comes back!! 

I come from Germany and my english isnt realy good, please Be Patient 
i Would prefer to read every page in this Thread but my english is to Bad 

Does anybody had the Same Problem (Hyperhidrose) After taking Roaccutan and can help me??? Any Medications/drugs??
does anybody Know what is going on with my Body??

please help me [Edited image out] [Edited image out] 
i cant and won't live with this Problem [Edited image out] 

Hope anybody reply 

you have whats called TEWL.  basically it confirms your skin is damaged from accutane, and cant hold onto the water.  you literally feel dried out.  evening primrose oil (GLA) is the only thing that i come up with.

Thank you so much for your reply 
okay TEWL i have Never heard before  Sounds intresting, is there a Different between TEWL and a "normal" Hyperhidrose
yes i feel dried out i Must Drink every 30 Minuten, sometimes more and have headache
Funnily enough i have two cans of CLA capsules (Linols¤ure), but i havent tried them. Is that the Same what you use?
it's sold here for weight less
can you give me informations about dosage and effect?
 

On 10/28/2015 at 9:10 PM, marlin15 said:

On 10/28/2015 at 12:28 PM, tryingtohelp2014 said:

On 10/28/2015 at 6:54 AM, BillionProblems said:

Hey guys, 
i am so happy that i found this Forum! 3 years ago i took Roaccutan (isotetrinoin), but Not Long and low dose. I had big side-Effects and stopped taking Roaccutan
My main Problem is the Hyperhidrose (extreme sweating)
i was at 10 Different doctors und tried Many Many Medications: 
somodren
vagantin 
opipramol 
sage tea 
a lot Minerals and Vitamines 
and at Last Zyprexa (olanzapin), which helped me to stop sweating for 1-2 months, bug slowly the Hyperhidrose comes back!! 

I come from Germany and my english isnt realy good, please Be Patient 
i Would prefer to read every page in this Thread but my english is to Bad 

Does anybody had the Same Problem (Hyperhidrose) After taking Roaccutan and can help me??? Any Medications/drugs??
does anybody Know what is going on with my Body??

please help me   
i cant and won't live with this Problem  

Hope anybody reply 

you have whats called TEWL.  basically it confirms your skin is damaged from accutane, and cant hold onto the water.  you literally feel dried out.  evening primrose oil (GLA) is the only thing that i come up with.

tryingtohelp, you sound very knowledgeable. any idea why the entire skin of my body is thinning. This is gradual, and it started right after accutane usage. Its the weirdest thing. I know they say when you're on accutane, your skin is more thin and fragile, but mine never recovered, and is getting worse.

On 10/29/2015 at 6:49 AM, tryingtohelp2014 said:

On 10/28/2015 at 1:17 PM, BillionProblems said:

On 10/28/2015 at 12:28 PM, tryingtohelp2014 said:

On 10/28/2015 at 6:54 AM, BillionProblems said:

Hey guys,
i am so happy that i found this Forum! 3 years ago i took Roaccutan (isotetrinoin), but Not Long and low dose. I had big side-Effects and stopped taking Roaccutan
My main Problem is the Hyperhidrose (extreme sweating) [Edited image out]
i was at 10 Different doctors und tried Many Many Medications:
somodren
vagantin
opipramol
sage tea
a lot Minerals and Vitamines
and at Last Zyprexa (olanzapin), which helped me to stop sweating for 1-2 months, bug slowly the Hyperhidrose comes back!!

I come from Germany and my english isnt realy good, please Be Patient
i Would prefer to read every page in this Thread but my english is to Bad

Does anybody had the Same Problem (Hyperhidrose) After taking Roaccutan and can help me??? Any Medications/drugs??
does anybody Know what is going on with my Body??

please help me [Edited image out][Edited image out]
i cant and won't live with this Problem [Edited image out]

Hope anybody reply

you have whats called TEWL. basically it confirms your skin is damaged from accutane, and cant hold onto the water. you literally feel dried out. evening primrose oil (GLA)is the only thing that i come up with.

Thank you so much for your reply
okay TEWL i have Never heard beforeSounds intresting, is there a Different betweenTEWL and a "normal" Hyperhidrose
yes i feel dried out i Must Drink every 30 Minuten, sometimes more and have headache
Funnily enough i have two cans of CLAcapsules(Linolsaure), but i havent tried them. Is that the Same what you use?
it's sold here for weight less
can you give me informations about dosage and effect?

not CLA... GLA. if you google search TEWL and accutane... some GLA studies come up.

On 10/28/2015 at 9:10 PM, marlin15 said:

On 10/28/2015 at 12:28 PM, tryingtohelp2014 said:

On 10/28/2015 at 6:54 AM, BillionProblems said:

Hey guys,
i am so happy that i found this Forum! 3 years ago i took Roaccutan (isotetrinoin), but Not Long and low dose. I had big side-Effects and stopped taking Roaccutan
My main Problem is the Hyperhidrose (extreme sweating) [Edited image out]
i was at 10 Different doctors und tried Many Many Medications:
somodren
vagantin
opipramol
sage tea
a lot Minerals and Vitamines
and at Last Zyprexa (olanzapin), which helped me to stop sweating for 1-2 months, bug slowly the Hyperhidrose comes back!!

I come from Germany and my english isnt realy good, please Be Patient
i Would prefer to read every page in this Thread but my english is to Bad

Does anybody had the Same Problem (Hyperhidrose) After taking Roaccutan and can help me??? Any Medications/drugs??
does anybody Know what is going on with my Body??

please help me [Edited image out][Edited image out]
i cant and won't live with this Problem [Edited image out]

Hope anybody reply

you have whats called TEWL. basically it confirms your skin is damaged from accutane, and cant hold onto the water. you literally feel dried out. evening primrose oil (GLA)is the only thing that i come up with.

tryingtohelp, you sound veryknowledgeable. any idea why the entire skin of my body is thinning. This is gradual, and it started right after accutane usage. Its the weirdest thing. I know they say when you're on accutane, your skin is more thin and fragile, but mine never recovered, and is getting worse.

I believe its a collagen problem imo. Accutane causes a glycine deficiency by hyper activating the GNMT enzyme. Glycine is the major amino acid in collagen.

im currently taking

8000mg of Glycine powder mixed with some Glutamine

600 mg of magnesium glycinate (more glycine... docotors best brand) with some P5P

10 mg Manganese

tryingtohelp, you sound veryknowledgeable. any idea why the entire skin of my body is thinning. This is gradual, and it started right after accutane usage. Its the weirdest thing. I know they say when you're on accutane, your skin is more thin and fragile, but mine never recovered, and is getting worse.