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Repairing the long-term damage from Accutane

 
MemberMember
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(@user461766)

Posted : 07/26/2015 4:08 am

Noticed the same thing when drinking and smoking, addicted to cigs and coffee. Cocaine also works wonder for mood and overall mental activity. Its definitely low dopamine. But I guess further ruining your body is not the answer. And stay away from serotonergic drugs, they just gonna mess you even more.

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MemberMember
960
(@tryingtohelp2014)

Posted : 07/26/2015 3:57 pm

Cure the fatty liver, cure accutane side effects.... an old patent.

 

 

The pathological effect of retinoid is ameliorated by a suitable dose of a rescuing agent selected from the group consisting of choline chloride, methionine, betaine, biotin and inositol, the rescuing agent having the property of preventing formation of fatty liver.

 

The experimental evidence presented herein clearly establishes that a group of agents known to prevent formation of fatty liver, when administered in sufficient doses ameliorates the pathological changes induced by retinoids. Without being bound to any theory, it is suggested that these agents presumably accelerate metabolism and excretion of retinoids thereby reducing their toxic or pathological effects.

 

 

SO.... manganese is needed for choline and biotin utilization. it is also needed for glycoslyntransferes (the way accutane metabolites are eliminated from the body)

 

Manganese

Choline

Inositol

TMG (betaine)

methionine

 

https://www.google.com/patents/US4649040

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MemberMember
70
(@whackutane)

Posted : 07/27/2015 6:13 am

Noticed the same thing when drinking and smoking, addicted to cigs and coffee. Cocaine also works wonder for mood and overall mental activity. Its definitely low dopamine. But I guess further ruining your body is not the answer. And stay away from serotonergic drugs, they just gonna mess you even more.

have you tried taking supps to increase dopamine to see what happens?

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MemberMember
14
(@marlin15)

Posted : 07/27/2015 3:44 pm

well, got back from the gastroenterologist today. performed an endoscopy. woke up from the anesthesia to find out i have celiac. have to wait for the biopsy but he said my folds were abnormally thin which is seen in celiac patients.

 

 

i know the fucking accutane did this to me. while you can say autoimmune is for the genetically predisposed, i know this fucking drug did this to me. So fucking depressed. Not because i can't eat gluten, its the mere principle of how this fucking pill fucked my entire life. i know i can manage it, its still the actual thought that i and WE shouldn't be in this fucking position. i want to just shove my fucking gaunt face full of gluten hoping it will give me colon cancer and finally just kill me. IBS, Chrons, all that shit that everyone has is worse than me, I can actually manage it. But to think that it can trigger an autoimmune reaction? fucking bizzaro world.

 

I'm so close to just cashing in my life. Just someone do me in. I'm too much of a pussy to do it myself.

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MemberMember
0
(@nevertakeaccutane)

Posted : 07/27/2015 6:59 pm

Hi guys. Another sufferer here who got his life ruined by accutane. I plan to make a recovery. Is there anyone on the east coast u.s. particularly tristate area that would like to try something new to make a change?

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MemberMember
157
(@tanedout)

Posted : 07/29/2015 4:11 pm

Cure the fatty liver, cure accutane side effects.... an old patent.

 

 

The pathological effect of retinoid is ameliorated by a suitable dose of a rescuing agent selected from the group consisting of choline chloride, methionine, betaine, biotin and inositol, the rescuing agent having the property of preventing formation of fatty liver.

 

The experimental evidence presented herein clearly establishes that a group of agents known to prevent formation of fatty liver, when administered in sufficient doses ameliorates the pathological changes induced by retinoids. Without being bound to any theory, it is suggested that these agents presumably accelerate metabolism and excretion of retinoids thereby reducing their toxic or pathological effects.

 

 

SO.... manganese is needed for choline and biotin utilization. it is also needed for glycoslyntransferes (the way accutane metabolites are eliminated from the body)

 

Manganese

Choline

Inositol

TMG (betaine)

methionine

 

https://www.google.com/patents/US4649040

 

That's a good find! The study does appear to focus on excreting retinoids from the liver however (which would occur naturally anyway) after treatment, so I'm not sure if this combination of supplements would actually go some way to repairing the damage left behind (i.e. tane sides) but a number of the items have led to some improvements to some, so would be interesting to try the combination in a moderate dose.

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MemberMember
157
(@tanedout)

Posted : 07/29/2015 4:30 pm

Noticed the same thing when drinking and smoking, addicted to cigs and coffee. Cocaine also works wonder for mood and overall mental activity. Its definitely low dopamine. But I guess further ruining your body is not the answer. And stay away from serotonergic drugs, they just gonna mess you even more.

Well this could well be down to allopregnanolone. Drinking alcohol increases allopregnanolone, significantly if you've been drinking heavily, and people have often noted reduced sides after a big night out drinking, see this study;

 

http://www.ncbi.nlm.nih.gov/pubmed/12700685

 

Interestingly finasteride (an 5ARI like accutane with very similar/same side effects) has been linked to a reduction in allopregnanolone, even referenced on allopregnanolones wiki pages, so it's likely tane has affected normal production of this in us.

Depression, anxiety, and sexual dysfunction are frequently-seen side effects of 5-reductase inhibitors such as finasteride, and are thought to be caused, in part, by interfering with the normal production of allopregnanolone

https://en.wikipedia.org/wiki/Allopregnanolone

 

Allopregnanolone levels can be increased by taking pregnenolone (note different spelling) of which excess is converted to allopregnanolone. I've actually got some 10mg caps as I a fin sufferer on Longecity found this significantly improved his brain fog symptoms (90% reduction), but I've yet to really try it properly.

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macleod, macleod and macleod reacted
MemberMember
960
(@tryingtohelp2014)

Posted : 07/29/2015 7:10 pm

 

Noticed the same thing when drinking and smoking, addicted to cigs and coffee. Cocaine also works wonder for mood and overall mental activity. Its definitely low dopamine. But I guess further ruining your body is not the answer. And stay away from serotonergic drugs, they just gonna mess you even more.

Well this could well be down to allopregnanolone. Drinking alcohol increases allopregnanolone, significantly if you've been drinking heavily, and people have often noted reduced sides after a big night out drinking, see this study;

 

http://www.ncbi.nlm.nih.gov/pubmed/12700685

 

Interestingly finasteride (an 5ARI like accutane with very similar/same side effects) has been linked to a reduction in allopregnanolone, even referenced on allopregnanolones wiki pages, so it's likely tane has affected normal production of this in us.

>Depression, anxiety, and sexual dysfunction are frequently-seen side effects of 5-reductase inhibitors such as finasteride, and are thought to be caused, in part, by interfering with the normal production of allopregnanolone

https://en.wikipedia.org/wiki/Allopregnanolone

 

Allopregnanolone levels can be increased by taking pregnenolone (note different spelling) of which excess is converted to allopregnanolone. I've actually got some 10mg caps as I a fin sufferer on Longecity found this significantly improved his brain fog symptoms (90% reduction), but I've yet to really try it properly.

Alcohol depletes Vitamin A from the liver

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MemberMember
7
(@wecangetbetter)

Posted : 07/30/2015 11:44 am

 

 

Hey guys like many of you I am experiencing prolonged side effects from an accutane course over 2 years ago, and I am trying to understand what can be done to repair/reverse the damage. However, as much I would like to read through 347 pages I simply do not have that time, so I was hoping if someone could be kind enough to summarize the most effective solutions that this thread has produced. Thanks!

Here's a quick summary of what works- nothing

Pretty much, lol. However, if you change your diet, exercise, and find supplements that work for you, you can look at a 2-3% better quality of life.

There is no 100% cure, but recovery up to 50-75% is possible in my oppinion.

This is complete and utter bullshit guys. There has been plenty of great incite in this thread, but some of the people currently posting are really derailing this thread with their negativity, but I feel for you. Get your pessimistic attitudes away from those who are trying to get better and remain optimistic about getting better. Again improvement doesn't happens over night. With diet changes towards more organic foods such as fruits and vegetables, supplements, exercise, and rest, I have made so much improvement since I first posted and since this whole nightmare began 2 years ago. I never thought I'd feel like this again after how bad I was feeling, but the improvements I have made have given me hope, and where this whole mess has brought me to what I feel is my life calling, and thats Nutrition. Will post soon what has helped me because I definitely believe I have improved significantly.

 

 

Have you guys with ED issues tried NoFap for 90 days or more?

Is the ED being caused mean that you can't even get hard by manual stimulation?

I dont try it, it just happens. Weeks pass and I cant remember when I last ejaculated. I have no urge to have sex or no load to ejaculate. It is just how old people live.

I can get an erection with manual stimulation or if I have a little libido I can get it up.

But before accutane I was ready for 7/24. I never had any kind of ED problem, and I had to do it every two or three days. Usually everyday.

Sounds like you might be deficient in Zinc, but that doesn't mean you may not be eating enough Zinc, you may not be absorbing nutrients properly. And to improve that you must make diet and life style changes, and include a probiotic in your regimen

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MemberMember
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(@wecangetbetter)

Posted : 07/30/2015 12:03 pm

On 7/3/2015 at 2:40 AM, Ottovisual said:

 

On 6/26/2015 at 12:47 AM, Trapt said:
On 7/4/2014 at 6:18 AM, Ottovisual said:

Reporting in.

5 weeks using RSO now.

Total ingested 5 grams.

To be clear, the RSO is still dominating me at this moment. If things are going better/worse, the next week it could be vice versa.

3 months after my last dosage I can give a objective review on side effects.

I started a new job this week which involves a lot of driving so I had to quit the daytime dose because I can't risk having a fuckup with dosing and driving.

What happens is the RSO produces massive amounts of melatonin which is a big healer but also a big sleeper. If someone is ill, the first thing they advise is to take a good night of sleep right ? Imagine having a week of sleep pushed into 1 night.

Also like some already posted, your short term memory is pretty much in standby modus when the RSO is active ( probably its easier to induce sleeping this way ).

If I take a night (big) dose at 8 oclock I feel the melatonin 24 hours and feel quite sleepy the whole 24 hours.

If I dont take a dose, I will get massive amounts of energy, to the point where I want to run over the whole world. I feel like a little boy again playing in the woods with no energy limit. ( maybe to rebound the massive melatonin wearing off ).

The second week there was I point where I got random "new" youth memories. It felt like a door opened to a part of the brain which was locked due to depression.

The moment when I got these memories it felt like synchronizing with my old me, I remembered who I was, I felt empathy again. Instead of black & white I felt colors.

Today I also skipped the daytime dose and I can feel it wearing off when I stop my shift in the afternoon.

I got home and I really really wanted to have sex with my girlfriend. I wanted to touch her body. I am looking for subtle words to explain this. I felt like a Greek god

[Edited link out]

I cannot emphasize this enough though: Moments happen, they make me smile but whether its permanent or not I cannot tell at this point, I need to be off RSO for quite some time.

Currently I'm fixing the dosing issue, the key is consistency and tolerance. There comes a point where you ingest 1 gram a day and the only side effect is a good night rest. If I ingest 1 gram at my current tolerance point, I will be in lalaland for some days.

As for ingestion, I read somewhere Rick ( or one of his associates ) said the goal is to get the RSO to the stomach. I put my RSO in a vitamin like capsule and swallow it. About 1 hour later I feel it kicking in and then I can pull 12 - 16 hours of sleep.

I tried different ways of ingestion, but this one is the easiest and most potent for me on top of that it follows the same route as accutane did so it can repair the whole accutane route. Rectal is said to be the most potent because of all the large blood vessels there and direct absorption into the blood.

Recommended is 1 small daytime dose in the morning and a big sleeper for the evening.

All the best,

Ottovisual,

Can you give us an update with the RSO? What were your post-Accutane side effects? What side effects disappeared with the RSO? What side effects still remain? Are you still using it? Thanks.

 

Hey everybody,

Dig in my archive of posts and you will find my full symptons.

I have been doing great, I would lie if I said I'm 100% cured but the good days outnumber the bad days.

Symptons that remained positive after a low protocol of RSO:

- Weight: I lost about 6-7 KG's after accutane. I was unable to regain those Kg's no matter how hard I trained, no matter what I ate. This is fully restored, I'm currently doing weightlifting and the muscles grow and grow.

- Gum/Dental Health: My gums remain perfectly in shape, my dentist has 0 complains. Before the RSO treatment it was rubbish, retreating and irritated.

- Skin: No more dry skin.

- Libido: So, my libido went from 100 to 60 - 70 post accutane. At this point I would say I'm 90 again. Inmediatly after accutane I got a girlfriend and we are six years together. If I was single I would be 100 again I'm sure. What I noticing now is when I'm flirting with a girl I feel the blood charging my penis and a instant boner is following. Pre-RSO this wasn't the case.

- GI tract: RSO did alot for my GI-Tract, only thing I'm doing now is a probiotic and good fermented food. I have regular bowels and the texture and everything is perfect.

This that still remained negative / midly negative.

- Brain fog. Although people said my personality positively changed when I took RSO ( and they didnt know I took it ) my brain didn't returned back to the extreme sharpness I had before accutane.

Pre-accutane all these verbally options shooted from my sub-councious into my counsciousness when I was discussing something. Post-accutane I felt like a child, just following other people and no input from my side. After the RSO my memory improved ALOT, these random youth memories were shooting through my brain and that made me very very happy.

But the brain fog / alertness pretty much remained the same.

These months I supplemented with some nootropics and Astaxanthin. Now the Astaxanthin pretty much clears my brain fog and give me ALOT of clarity and when I add a nootropic like Piracetam or Noopept I'm 100% myself again. I also firmly believe these nootropics can restore our disrupted brain networks. I'm making 17 hours a day again just like pre accutane and have alot of energy.

Eye-Floaters: Now I speak alot of people who smoked weed and they reported that the floaters increased when using and it took them some years to get some relieve again. Also when I use Astaxanthin and a Nootropic it decreases alot. Also, the only thing we can change about floaters is the perception of floaters. They are always there.

Tinnitus: Decreased from 100 to 60. Again I think this is a brain thing, I dont think it's my ears, I think there are some nerves in my brain over-sensitive or over-simulating.

Sleep: While on RSO you sleep like a baby. I think sleep is a big focus area for us. I dont think we sleep like we should, and we dont recover like normal people do. So while on the RSO the sleep was perfect, but after it was crap.

Just a quick summary of my current health.

My current stack

Astaxanthin - for brain fog

Piracetam or Noopept or Aniracetam - To stimulate my brain again and repairing the disrupted brain networks

ZMA - before bed, to improve the quality of my sleep. This is one the most important supplements I take and very cost effective. Make me dream again so I know I'm doing quality sleep

There are days where I have the full access to my intelligence, where all the suggestions are shooting through my counciousness and the words just roll out my mouth. Where I have full control of the words I'm saying and where I can plan the sentence visually in my head so I can choose the strategy in a discussion. I also can predict people's reaction based on their personality. Just like pre-tane. So things look very good.

These last years are basically years of detoxifying and then years of rebuilding my body and soul. And I'm current;y rebuilding my body and soul.

Still there are days where I have full blown brain fog but this is always followed on a bad night of sleep.

I'm off to get some food.

If you have any questions, just Pm me.

Oh yeah, for the nootropics, some people experience lowered libido for the first weeks. Just read the reports on reddit.

- Otto.

Wow great post, hope this instills some optimism in fellow posters. Astaxanthin is an amazing supplement. What is this RSO you speak of? And a little a while ago I was trying out Melatonin, since it's a hormone the body produces it seemed risky to fool around with, but I was believing if it was used correctly it could really help. I was experimenting with melatonin and would fall asleep like in 30 minutes, but would always wake up so tired and literally wouldn't be able to get up for school and I would just go back to sleep. I believe the dosage was maybe too high and when I was waking up it was still in my system? I'm not sure. Also you mentioned the ZMA and dreaming. around the time i started accutane i started smoking weed, and I would stop dreaming. Then i was sober for 6 months and my dreams returned and I was feeling great. Now I'm smoking again, and not really dreaming is that a bad thing? Does that mean I'm not properly resting? I've been working out a lot so I feel like I've been getting adequate rest, but if dreaming is important for rest cycle and to get proper rest, I may just have to put the weed away. Although I really like weed's upside and think it benefits me

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MemberMember
299
(@macleod)

Posted : 07/30/2015 1:29 pm

Optimism is not insight. There is no positive or negative. There is fact and fiction. As guinea pigs, with no formal medical background, the best thing we can do is work together forming our own hypothesis and collectively try to experiment and disprove each thesis.

 

I've completely changed my diet (I rarely even eat bread, let alone a single soda). I also exercise. I can see physical and health improvements and I recommend it to everyone post Tane since it can only benefit those with digestive issues. However, its impact on mental and overall well being is minimal, because as most of us agree, the problem lies in the hormonal/adrenal systems, and it would take a significant amount of any food/diet to really impact our hormones.

 

Now to continue the topic at hand:

 

Alcohol, yes. It was a great substance for me years 1 - 5 post tane. It helped to regulate my sleep, got rid of my anxiety, made life more enjoyable, social with my friends, food taste better, you name it. I think the posters above are really on to something when they say it affects dopamine and or pregnanolone. So, lets continue researching this.

 

Unfortunately, as tolerance increased, ethanol amounts also had to increase, leading to the negative effects. My pancreas has taken a toll (mainly because of the beta cell's not being able to regenerate normally due to Accutane's effects on cell proliferation). However, I have managed my pancreas issues and have actually seen improvements healing this organ with fasting and supplements.

 

Now some 'positive' firsthand experience from someone 8 years post tane:

 

Diet, exercise, supplements (all around great for the body +10-15%, slight mood enhancer +2-3%)

Fasting (good in moderation, able to regenerate internal cells)

Ethanol (good in moderation, very bad in excess)

Alprazolam (great scientific find, good overall drug in moderation, able to regulate sleep/anxiety)

Melatonin (good in small amounts 1.5 mg under tongue 30min before bed time, 9+hours of sleep with dreams, wake up with energy and erections) (not so good in large amounts 3+ mg, 5-6 hrs of sleep, no dreams)(said to lower estrogen levels, may be good for men post tane)

Sunlight/Tanning (good in moderation, 1-2 hrs a day, great for energy and sleep)

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MemberMember
7
(@wecangetbetter)

Posted : 07/30/2015 2:16 pm

Drinking is not a solution though. I feel great when I drink too, but it's self medicating just masking and further complicating health problems. I rarely drink these days, and I advice everyone who has gone on Accutane to stay away.

Optimism is not insight. There is no positive or negative. There is fact and fiction. As guinea pigs, with no formal medical background, the best thing we can do is work together forming our own hypothesis and collectively try to experiment and disprove each thesis.

 

I've completely changed my diet (I rarely even eat bread, let alone a single soda). I also exercise. I can see physical and health improvements and I recommend it to everyone post Tane since it can only benefit those with digestive issues. However, its impact on mental and overall well being is minimal, because as most of us agree, the problem lies in the hormonal/adrenal systems, and it would take a significant amount of any food/diet to really impact our hormones.

 

Now to continue the topic at hand:

 

Alcohol, yes. It was a great substance for me years 1 - 5 post tane. It helped to regulate my sleep, got rid of my anxiety, made life more enjoyable, social with my friends, food taste better, you name it. I think the posters above are really on to something when they say it affects dopamine and or pregnanolone. So, lets continue researching this.

 

Unfortunately, as tolerance increased, ethanol amounts also had to increase, leading to the negative effects. My pancreas has taken a toll (mainly because of the beta cell's not being able to regenerate normally due to Accutane's effects on cell proliferation). However, I have managed my pancreas issues and have actually seen improvements with healing this organ with fasting and supplements.

 

Now some 'positive' firsthand experience from someone 8 years post tane:

 

Diet, exercise, supplements (all around great for the body +10-15%, slight mood enhancer +2-3%)

Fasting (good in moderation, able to regenerate internal cells)

Ethanol (good in moderation, very bad in excess)

Alprazolam (great scientific find, good overall drug in moderation, able to regulate sleep/anxiety)

Melatonin (good in small amounts 1.5 mg under tongue 30min before bed time, 9+hours of sleep with dreams, wake up with energy and erections) (not so good in large amounts 3+ mg, 5-6 hrs of sleep, no dreams)(said to lower estrogen levels, may be good for men post tane)

Sunlight/Tanning (good in moderation, 1-2 hrs a day, great for energy and sleep)

Good incites. Sunlight is very important and can help with depression. With healthy eating, supplementation, and taking Astaxathin, I go out in the sun all the time, without really sunburning and now my skin tans very nicely,I get compliments all the time. I've also read about Melatonin and I really think it can benefit us people who have been damaged by Accutane because we need more rest than the average person to heal our bodies, and I've read that it lower estrogen also which could benefit a lot of people here, but I really don't know how to best use it

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MemberMember
7
(@wishicouldcry)

Posted : 07/31/2015 8:09 pm

I am having a hard time socializing and just feel pretty on edge all damn day, not sure how much more I can take living in my own brain. I feel like god isnt real anymore. accutane isnt even funny. i absolutely have no idea what to do in the meantime waiting. have been eating healthy as hell and walk around a factory all day, plus its been sunny here and ya that does NOT help with accutane sorrry. its just hot and annoying. im a dull piece of shit. i was funny and in a way kind of autistic, but in a really good loveable way. now i just feel straight retarded. some people think i do drugs, some people think i m just weird but accutane definatly stole my ablitiy to flaunt who i am, i am now left "acting" who i wish i was. this is one big fucked joke. im done u guys. i know you understand. im done just chexkign this thread every day. does anyone want to talk? [removed]. give me a text or call.

apparetnly i took just enough accutane to sink this ship, its been exactly 5 years

btw as the last few pages have said on here 50% recovery would be nice but its more like in the 20% range and 18% of that is just getting use to my shrunkedn brain.

my biggest annoyance is how much energy it takes to have a normal conversation with people, its hard work. i dont want to seem lame, so i pretend and have to dig so deep to think of things to keep conversation flow going.

there is no way in hell i have the stamina to pick up a girl and have a good time. i would end up just sitting there . im not trying to sound that bad but im so damn depressed like always. worrysome thoughts suck. my thought pattern is so fucked. when i see a friend i freak out. im sorry but shouldnt i as a human SMILE when i see a friend?

On 7/17/2015 at 5:11 PM, dortheatos said:

Thanks man, I guess I'm going to shoot myself in the head now ;)

A FUCKING MEN. Honestly we are the chosen ones. i do not suggest this but this is where im at. my mental health is absolutely shattered and then this guy says were damaged for good. god DAMN.

I also have penis issues and shrunken cold to touch. seriously i never thought id be on a damn thread typing this. i should be out driving trucks and enjoying my weekend, but my brain is either on or off and id perfer to just lie here "off" because ive been on all week. adrenal problems much?

i just ordered a bunch more suppliments, i guess im not going to just kill myself and give up. ill be the one, ill take fuckin 10 of each pill a day, anything to bring me to life. if vitamin A posioning fucked me left then maybe vitamin b posioning will bring me back right. i have no idea what im talking about but i am going to try a month of some HEAVY healthy eating, full size meals, (maybe fast on 2 days) and a SHIT ton of suppliments. if it works, ill do it for the rest of my shit life i GUESS.

screw accutane.

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MemberMember
7
(@wishicouldcry)

Posted : 07/31/2015 8:34 pm

Oh did i mention i dont have interest in jack shit anymore. id rather be depressed for some reason

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MemberMember
299
(@macleod)

Posted : 07/31/2015 11:00 pm

I'm very sorry to hear your frustrations. Believe me, a lot of us know your pain. But, lets try to look at the big picture. We are just borrowing this thread on an acne site. There is a lot of useful information we need. Please, lets stay on topic and not scare the moderators and other members with our blunt and grey world outlook.

 

There was one point and time 1 yr post tane where I was unable to run for more than 5-10 minutes without my leg and calf muscles becoming inflamed (shin splints) (I believe accutane atrophies the developing body early) But, I kept trying at it. Ice and run. Run and ice. Eventually, I overcame the shin splints. Then as my distance increased, my knees started developing tendonitis, but yet again with rest, massage, and supplements I actually beat that too. I can now keep up with healthy folk.

 

So, I actually do think we can make progress. Don't feel discouraged or hopeless. I been there. I think everyone should stick around as long as they can. No doubt medicine and science will make progress as well bringing hope to us all.

 

 

 

Hey, for some good news! Looks like Swanson supplements has came to Ebay. I stumbled upon their new account and it seems their prices are lower than everyone else's. Just wanted to share with y'all.

 

http://www.ebay.com/usr/swanson_vitamins?_trksid=p2060353.m1438.l2754

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MemberMember
299
(@macleod)

Posted : 08/02/2015 4:24 am

Always remember: Roche is a special place.

 

 

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timatron, User461766, timatron and 3 people reacted
MemberMember
33
(@ihateaccutane)

Posted : 08/02/2015 4:58 am

We must create a forum web site. One topic with 350 pages is no good (is good but could be better)

Any webmaster here? I can spend some for hosting costs.

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MemberMember
20
(@user461766)

Posted : 08/02/2015 8:18 am

Always remember: Roche is a special place.

 

There is a special place in hell for all of them. About the site, cool, personally don't have any experience in webmastering, altough I would happily contribute

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MemberMember
157
(@tanedout)

Posted : 08/02/2015 12:55 pm

We must create a forum web site. One topic with 350 pages is no good (is good but could be better)

Any webmaster here? I can spend some for hosting costs.

 

It would be good to have an subforum on acne.org for people suffering from accutane sides. I don't know if the site admins would allow this, but I think even with another forum setup, a lot of people would still end up on here. There is already an accutane suffers subforum on All Things Males, but it's hardly used.

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MemberMember
180
(@roland1968)

Posted : 08/05/2015 3:02 pm

Hi all, what do you think about this. I found this comment in a rosacea forum and thougt, i copy it here to this thread.

 

 

"Accutane side effects GONE!! after 3 years

 

Hey guys, i have a very good message and iam happy to share it with you. Short Version of my Story:

 

I took accutane around 3 years ago, short time after i stop taking accutane my symptoms start and get worse by time, my symptoms are:

 

 

Anxiety

Hair loss

Hair thining

Grey hairs

Depression

facial flushing

dry Skin

sensitive skin

Joint pain

and so on....

 

 

Since 3 YEARS i search and looking for a solution, i try so many pills and stuff, i spend up to 3000$ for stuff. nothing works, realy nothing gave the relief of symptoms which i experience at the Moment and i think its important to share this, maybe it helps someone of you.

 

 

 

After i stop accutane, i see so many docs (20-25 i think, cant remember), and nothing helps me.

 

 

 

Than i start to Change my Food, glut free, sugar free, vegetarian, blablabla........... again, nothing helps!! Than i search threw the Internet 24/7 and loose my Job, because i wasnt able to go to work. I read good stories about Magnesium for anxiety.... so i buyed Magnesium and take it. withing the first dose, 90% of my symptoms went away, but it only least for 3-4 days and the symptoms came back, so i stop taking Magnesium......... after 4 months i try it again...... and again, symptoms went away for a few days, same storie.......... and i stop taking it again. i thought it was Placebo maybe or something, but i never experienced Placebo with any other medication.

 

 

i try soooo many medications, yout cant Image. many Kind of ssris, beta blocker, alphablocker, anti histamine, vbeam, blablabla...........

 

 

 

so the end of the Story is: i take Magnesium since 8 days and all i have to say: THANK YOU GOD! now i know, its definatly Magnesium deficieny in MY CASE! the "trick" is, to cut out SUGAR!! why? Because sugar kill your Magnesium Storages, your Body Need 54 Magnesium Moleculs to "destroy" 1 (ONE!!) sugar molecul. you can Google it. there are many reports and studies about it.

 

 

 

I know that some medications induce a Magnesium deficiency, like some SSRI, duiretika, Betablocker, etc. i think that accutane acts the same way and induce a Magnesium deficiency.

 

and dont trust your Docs if they do simple blood tests for Magnesium Status, its not detectable in the blood, because only 1% of the Magnesium circulates in the blood. its not possible to test the intraceullul¤r Magnesium and 80% of the Population have Magnesium deficiency.

 

 

my recommendations for you:

 

 

- take Magnesium, start with 300 mg (glycinate, taurate, orotat) and go up to 800 mg for atleast 1 months!

 

 

- avoid Magnesium OXID, aspartate, Glutamate and Citrat (bad for stomach)

 

- Cut out wheat and sugar

 

- eat only vegetables, fish, chicken, fruits.

 

- dont eat processed Food

 

- take Vitamin b6 with your Magnesium, its the most important Vitamin to resorb Magnesium

 

- give it atleast 1 months

 

 

 

My symptoms are 90% gone, and i think its improves with time. i never thought that i could say that, but now i LOVE MY LIFE. My anxiety is 100% gone, dry Skin much better, hairs much better, flushing around 80% gone, no more warm rooms, exercise or embreassment flushing.

 

 

 

http://drcarolyndean.com/2012/10/magnesium-menopause/

 

 

 

best wishes and sorry for my bad english (LOL).

 

 

BYE! :-)"

 

http://www.rosaceagroup.org/The_Rosacea_Forum/showthread.php?32846-Accutane-side-effects-GONE!!-after-3-years

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MemberMember
960
(@tryingtohelp2014)

Posted : 08/05/2015 11:47 pm

Increasing RBP/ROH and or TTR levels could be a key. this article explains why we have vitamin A toxicity and night blindness at the same time.

[Edited link out]

[Edited link out]

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MemberMember
10
(@kokodu)

Posted : 08/06/2015 8:35 am

Maybe, but in my situation doesn't help to libido.
I have been taking 2,6 g citrate magnesium (400 mg pure magnesium) for 7 months and I don't see any difference.
Probably start a diet could help. Who knows?

so the end of the Story is: i take Magnesium since 8 days and all i have to say: THANK YOU GOD! now i know, its definatly Magnesium deficieny in MY CASE! the "trick" is, to cut out SUGAR!! why? Because sugar kill your Magnesium Storages, your Body Need 54 Magnesium Moleculs to "destroy" 1 (ONE!!) sugar molecul. you can Google it. there are many reports and studies about it.

Quote
MemberMember
70
(@whackutane)

Posted : 08/07/2015 6:40 pm

I just wanted to ay that for the last week I have been taking pretty big doses of L-tryosine and DL-phenylalanine (about 2g sometimes more each) and I have noticed massive increases in mood and general appreciation for life. Not all my symptoms have disapeared and I wouldnt say Im 100% cleared but I am defiantly on my way there now. Feeling 1000% better than I did two years ago.

 

My memory has improved and my brain fog has started to disapear.

 

This also comes after about 3 monts of nofap (PMO reboot) and also abstaining from Porn for over a year.

 

Im still pretty certain I have a copper toxicity from when I took accutane in Dec 2012 and this fix now will only be temporary to prove to myself thats what is happening.

 

My next course of action is to get a hair mineral analysis done and start balacing mineral levels correctly.

 

A member of a website caleld propeciahelp basically uncovered all this...

 

stating that like accutune, finasteride increases estrogen

 

which increases copper

 

Copper creats a toxic substance in the brain which basically breaks down dopamine and most likely other important sutff

 

Lack of dopamine is what causes depression memory loss and all that.

 

His name on the site is 'letsconvenience' and can be found only by a member search for authors in the advanced search function.

 

He goes on to state that the supplements I mentioned before worked well for about 2 months until they stated to diminish, most likely due to dopamine receptors.

 

He then tried to increase his dopamine receptors through the use of certain nootropics and while that did help he understood it was no permanent fix and eventually discovered copper toxicity and went down the path of Hair mineral analysis and supplementation mediated by a practioner called Alex Tuggle.

 

Anyway, check my posts and shit Ive been struggling with this for fucking ages.

 

KOI

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MemberMember
24
(@mike-san)

Posted : 08/08/2015 5:31 am

Interesting ...why not combat raised estrogen (if that is the cause) rather than the downstream effects? Will be very interested in your hair mineral results.

 

It's a bit of a jump to then postulate that high estrogen (if confirmed by a test) is the cause of your high copper (again, if confirmed), which is then the cause of low dopamine (impossible to test for).

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MemberMember
14
(@octopusfrog)

Posted : 08/08/2015 7:38 am

I just wanted to ay that for the last week I have been taking pretty big doses of L-tryosine and DL-phenylalanine (about 2g sometimes more each) and I have noticed massive increases in mood and general appreciation for life. Not all my symptoms have disapeared and I wouldnt say Im 100% cleared but I am defiantly on my way there now. Feeling 1000% better than I did two years ago.

 

My memory has improved and my brain fog has started to disapear.

 

This also comes after about 3 monts of nofap (PMO reboot) and also abstaining from Porn for over a year.

 

Im still pretty certain I have a copper toxicity from when I took accutane in Dec 2012 and this fix now will only be temporary to prove to myself thats what is happening.

 

My next course of action is to get a hair mineral analysis done and start balacing mineral levels correctly.

 

A member of a website caleld propeciahelp basically uncovered all this...

 

stating that like accutune, finasteride increases estrogen

 

which increases copper

 

Copper creats a toxic substance in the brain which basically breaks down dopamine and most likely other important sutff

 

Lack of dopamine is what causes depression memory loss and all that.

 

His name on the site is 'letsconvenience' and can be found only by a member search for authors in the advanced search function.

 

He goes on to state that the supplements I mentioned before worked well for about 2 months until they stated to diminish, most likely due to dopamine receptors.

 

He then tried to increase his dopamine receptors through the use of certain nootropics and while that did help he understood it was no permanent fix and eventually discovered copper toxicity and went down the path of Hair mineral analysis and supplementation mediated by a practioner called Alex Tuggle.

 

Anyway, check my posts and shit Ive been struggling with this for fucking ages.

 

KOI

 

 

thanks for the update man. glad to hear some people are actually doing better. will look into this..

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