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Repairing the long-term damage from Accutane

 
0
(@Anonymous)

Posted : 08/27/2014 9:01 pm

For sexual problems you better test: ACTH, CORTISOL, ALDOSTERONE, RENIN, GLUCOSE. And of course bun/urea and creatinine. Optimal value:

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[Edited link out]

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37
(@chiron)

Posted : 08/28/2014 10:09 am

 

My dr says I have prostatitis. He prescribed me antibiotics and alphablocker. Should I use it? There is no pain in that area but other sympthons are common with prostatitis. Pills again

Please guys, give me some feedback. Do you have prostate problems (difficulty to urinate or frequent urination) as well?

I am about to get prostatitis treatment with antibiotics and I dont want to be missdiagnosed.

I have no pain during pee, but low steam, difficulty in urinate and sometimes frequent urination. Do you have the same?

Hey, I actually have the same problem. I believe it has to do with my prostate because I know prostate problems run in my family. The past few months or so I found it takes like a few seconds or more before I urinate. I don't feel the build up like I used to and the flow isn't that strong anymore. It doesn't hurt to pee or anything but I just don't feel the build up or have a strong stream. Also I don't have frequent urination, just takes a while before it comes out like I said. I was supposed to go to the urologist today but rescheduled it for next monday. I am concerned about having to go on drugs if I have an enlarged prostate because I know that the doc would prescribe me some if somethings wrong but really wouldn't want to take it. In a way though if I do have something wrong with my prostate(which I likely do due to my urination problems), maybe it is the cause of my ED, but also maybe not.

I wouldn't mind taking antibiotics but wouldn't want to take a drug for it.

I'll see what he says when I go and see what's wrong. I'll update when after next monday on what he said and what he chooses to do.

I had prostatitis a couple of times. After doing some research I realized that it may be related to stones in my prostate. Stones form when the body is dehydrated especially. I tend to get kidney stones as well. The good news is that apple cider vinegar mixed with water seems to disolve all manner of stones in the body: kidney, liver, prostate, gall and others. Also, when you wake up first thing in the morning drink 3 tall glasses of water. Don't eat for an hour afterward. this works wonders by hydrating your body after sleeping and not getting any water for a large chunk of time. This was a fad diet in Japan a few years back and man, it works. Started normal urination after that.

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33
(@ihateaccutane)

Posted : 08/28/2014 10:36 am

 

 

 

 

 

 

 

 

 

My dr says I have prostatitis. He prescribed me antibiotics and alphablocker. Should I use it? There is no pain in that area but other sympthons are common with prostatitis. Pills again

 

Please guys, give me some feedback. Do you have prostate problems (difficulty to urinate or frequent urination) as well?

I am about to get prostatitis treatment with antibiotics and I dont want to be missdiagnosed.

I have no pain during pee, but low steam, difficulty in urinate and sometimes frequent urination. Do you have the same?

Hey, I actually have the same problem. I believe it has to do with my prostate because I know prostate problems run in my family. The past few months or so I found it takes like a few seconds or more before I urinate. I don't feel the build up like I used to and the flow isn't that strong anymore. It doesn't hurt to pee or anything but I just don't feel the build up or have a strong stream. Also I don't have frequent urination, just takes a while before it comes out like I said. I was supposed to go to the urologist today but rescheduled it for next monday. I am concerned about having to go on drugs if I have an enlarged prostate because I know that the doc would prescribe me some if somethings wrong but really wouldn't want to take it. In a way though if I do have something wrong with my prostate(which I likely do due to my urination problems), maybe it is the cause of my ED, but also maybe not.

I wouldn't mind taking antibiotics but wouldn't want to take a drug for it.

I'll see what he says when I go and see what's wrong. I'll update when after next monday on what he said and what he chooses to do.

I had prostatitis a couple of times. After doing some research I realized that it may be related to stones in my prostate. Stones form when the body is dehydrated especially. I tend to get kidney stones as well. The good news is that apple cider vinegar mixed with water seems to disolve all manner of stones in the body: kidney, liver, prostate, gall and others. Also, when you wake up first thing in the morning drink 3 tall glasses of water. Don't eat for an hour afterward. this works wonders by hydrating your body after sleeping and not getting any water for a large chunk of time. This was a fad diet in Japan a few years back and man, it works. Started normal urination after that.

Thank you for that!

Possibilities so far:

1. Shrunken prostate due to low DHT (source:propeciahelp, but why people do not have problems while finasteride, but they have problems afterwards when they have pfs.)

2. Bacterial or non bacterial prostatis disease

3. Eating Acidosis

4. Stones and dehydration

 

I am not starting antibiotics for sure..

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0
(@Anonymous)

Posted : 08/28/2014 1:22 pm

Acids/toxins from foods are secondary (even if it block detox processes), primary cause of acidosis is natural cellular waste & lack of lymph filtration from the kidneys. Accutane is chemotherapy, it poison & kills a lot of cells, plus poisoning/destroying the intestine, causing even more waste & acidosis, more than you'll have naturally in 20+ years accumulated, only by taking it 6 month.

You really "age" (in a way of toxicity&acidosis accumulation + weakened glands) by taking this drug, you have health issue you should never have before reaching 40-60 years (except if you taked care of your body not eating crap products).

"Nobel Prize winner Alexis Carrel (born June 28, 1873, Sainte-Foy-les-Lyon, Fra. died Nov. 5, 1944, Paris) French surgeon, sociologist, and biologist. He received a 1912 Nobel Prize for developing a way to suture (stitch) blood vessels and laid the groundwork for further studies of blood-vessel and organ transplantation. He also researched preservation of tissues outside the body and the application of the process to surgery, and he helped develop the Carrel-Dakin method of flushing wounds with an antiseptic. His writings include Man, the Unknown (1935), The Culture of Organs (with Charles A. Lindbergh, 1938), and Reflections on Life (1952).
He found a way to keep living tissue cells alive indefinitely. By supplying needed nutrients and clearing away waste, not only did the cells under examination survive, they also showed no signs of deterioration. Dr. Carrel kept a chicken heart alive for twenty-nine years, and it seemed it would go on forever, as long as he continued to do those two things. When he failed to wash away tissue excretions in a timely manner, he would notice that the cells had lower vitality and increased deterioration. The heart finally died when a co-worker failed to clean away the excretions."
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223
(@gladiatoro)

Posted : 08/28/2014 5:10 pm

Yes anonyy the body runs on NUTRITION and certainly NOT TOXIC DRUGS , especially chemo drugs right now I'm taking a four combo herb supplement , hawthorn , garlic , bilberry and cayenne , excellent heart tonic / anti-cancer tonic and general immune system enhancer with obvious nutrients for the entire body , but I can't stress enough H2O due to our chronic dehydration and of course BAXYL .

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0
(@Anonymous)

Posted : 08/28/2014 6:08 pm

Nutrients are secondary, most important thing is proper cell environment (clean one), if it's not clean nutrients can't reach cells properly.

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1
(@sage1)

Posted : 08/28/2014 10:45 pm

Oh, how I long for the days when TUDCA was going to deliver us from evil. You people should heed Loeb's warning on antihistamines. "Most side effects are due to cross-reactivity with unintended receptors" (Wiki.). If you scour hair loss forums (and I am sure many of you are quite devout) you will notice that it is regularly mentioned. You can rest assured that the offending mode of action encompasses more than merely interrupting AR signaling. There is not much that is consistent with the world these days, but I can sure bet that an unsuspecting victim will be treated 'right' here.

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1
(@sage1)

Posted : 08/28/2014 11:11 pm

Indeed!!

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MemberMember
1
(@sage1)

Posted : 08/29/2014 3:35 am

One shouldn't bite the hand that feeds him. Onto other matters: oh, you got me good.

*You should have fiddled with the timestamp.

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MemberMember
33
(@ihateaccutane)

Posted : 08/29/2014 7:39 am

 

 

 

 

 

 

 

My dr says I have prostatitis. He prescribed me antibiotics and alphablocker. Should I use it? There is no pain in that area but other sympthons are common with prostatitis. Pills again

Please guys, give me some feedback. Do you have prostate problems (difficulty to urinate or frequent urination) as well?

I am about to get prostatitis treatment with antibiotics and I dont want to be missdiagnosed.

I have no pain during pee, but low steam, difficulty in urinate and sometimes frequent urination. Do you have the same?

Hey, I actually have the same problem. I believe it has to do with my prostate because I know prostate problems run in my family. The past few months or so I found it takes like a few seconds or more before I urinate. I don't feel the build up like I used to and the flow isn't that strong anymore. It doesn't hurt to pee or anything but I just don't feel the build up or have a strong stream. Also I don't have frequent urination, just takes a while before it comes out like I said. I was supposed to go to the urologist today but rescheduled it for next monday. I am concerned about having to go on drugs if I have an enlarged prostate because I know that the doc would prescribe me some if somethings wrong but really wouldn't want to take it. In a way though if I do have something wrong with my prostate(which I likely do due to my urination problems), maybe it is the cause of my ED, but also maybe not.

I wouldn't mind taking antibiotics but wouldn't want to take a drug for it.

I'll see what he says when I go and see what's wrong. I'll update when after next monday on what he said and what he chooses to do.

I had prostatitis a couple of times. After doing some research I realized that it may be related to stones in my prostate. Stones form when the body is dehydrated especially. I tend to get kidney stones as well. The good news is that apple cider vinegar mixed with water seems to disolve all manner of stones in the body: kidney, liver, prostate, gall and others. Also, when you wake up first thing in the morning drink 3 tall glasses of water. Don't eat for an hour afterward. this works wonders by hydrating your body after sleeping and not getting any water for a large chunk of time. This was a fad diet in Japan a few years back and man, it works. Started normal urination after that.

Thank you for that!

Possibilities so far:

1. Shrunken prostate due to low DHT (source:propeciahelp, but why people do not have problems while finasteride, but they have problems afterwards when they have pfs.)

2. Bacterial or non bacterial prostatis disease

3. Eating Acidosis

4. Stones and dehydration

I am not starting antibiotics for sure..

Sure I am not going to take antibiotics:

 

This pretty lady has drug poisioning too. Not accutane but abx.(had to put spaces to he link)

http:/ /youtu .be/ E8xpg2Wns4o

 

And this man:

http: //youtu. be/ 4oXGWRxs25g

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120
(@pido)

Posted : 08/29/2014 8:53 am

My body feels constantly dry. My skin is fragile, I need to use lip balm all the time, hangovers are horrible, my gums hurt because they get so dry. When I'm home I constantly drink water, but now when I'm back studying I can't drink that much and I've gotten dehydration symptoms: headaches, tiredness etc. God damn this site is slow btw.

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223
(@gladiatoro)

Posted : 08/30/2014 9:53 am

Pido .... welcome to the party....

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153
(@crank92)

Posted : 08/30/2014 10:26 am

Had a thorough read of one of the previous endocannabinoid papers I posted. Here are the highlights, although I'm aware this may only make sense to a select few.

D'Addario, C., Di Francesco, A., Pucci, M., Finazzi Agro, A., & Maccarrone, M. (2013). Epigenetic mechanisms and endocannabinoid signalling. FEBS Journal,280(9), 1905-1917.

It has also been observed that THC and cannabinol can (a) activate the ERK-MAPK cascade, a crucial event for gene activation during mitosis induction, and (b) inhibit gap-junction intercellular communication, required to relieve growth suppression of cells [107].

Altogether, these results show a new activity of eCBs as transcriptional repressors via epigenetic mechanisms and in, in the search of drugs able to reverse methylation abnormalities, they suggest a possible exploitation of eCB signaling in human diseases where DNA methylation is downregulated.

eCB-mediated transcription involves coordinated interactions of CB receptors with acetylases and deacetylases, methylases and demethylases. In addition, eCBs have the potential to trigger extranuclear signaling that activates several kinase cascades, which either directly modify histone tails or indirectly influence functions and/or recruitment of histone-modifying enzymes.

Indeed, epigenetic alterations are reversible and specific interventions that target different epigenetic pathways might have a major impact on health problems, eventually providing a new avenue for innovative therapeutic approaches.

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223
(@gladiatoro)

Posted : 08/31/2014 7:57 am

I guess we should have all read the package insert before taking this %^& . Side effects include....

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153
(@crank92)

Posted : 08/31/2014 11:10 am

"Side effects include side effects not listed on this leaflet"

The amount of hours I spent researching, reading, etc. Probably totalled more than the amount of hours in my final year of university. It definitely robbed me of more than a few % on my overall degree. -_-

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1
(@sage1)

Posted : 09/01/2014 3:04 am

Crank:

"An interesting factor and it is why I included the study that showed decreased T and DHT is that while I'm 'high' it is like I'm right back at square one. No libido, impotence and for whatever reason almost complete lack of cremastic reflex (which was reduced after isotretinoin treatment). I seem to experience a 'rebound effect' the next day that last for a couple of weeks once the high sensation wears off."

So you only mobilize a modicum of the negative and degenerative aspects of cannabis temporarily, because the 'negative' ultimately becomes a 'positive' in your estimation. Again, the rhetoric is impeccable. If you couldn't convert the 'negative,' there is little doubt that the readers wouldn't have been treated to it.

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223
(@gladiatoro)

Posted : 09/01/2014 10:04 pm

To sell chemotherapy as a " therapy" is the biggest deceit in the history of medicine . Whoever masterminded this CHEMO TORTURE deserves a monument in HELL.

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0
(@Anonymous)

Posted : 09/02/2014 1:58 am

Had a thorough read of one of the previous endocannabinoid papers I posted. Here are the highlights, although I'm aware this may only make sense to a select few.

 

D'Addario, C., Di Francesco, A., Pucci, M., Finazzi Agro, A., & Maccarrone, M. (2013). Epigenetic mechanisms and endocannabinoid signalling. FEBS Journal,280(9), 1905-1917.

It has also been observed that THC and cannabinol can (a) activate the ERK-MAPK cascade, a crucial event for gene activation during mitosis induction, and (b) inhibit gap-junction intercellular communication, required to relieve growth suppression of cells [107].

Altogether, these results show a new activity of eCBs as transcriptional repressors via epigenetic mechanisms and in, in the search of drugs able to reverse methylation abnormalities, they suggest a possible exploitation of eCB signaling in human diseases where DNA methylation is downregulated.

eCB-mediated transcription involves coordinated interactions of CB receptors with acetylases and deacetylases, methylases and demethylases. In addition, eCBs have the potential to trigger extranuclear signaling that activates several kinase cascades, which either directly modify histone tails or indirectly influence functions and/or recruitment of histone-modifying enzymes.

Indeed, epigenetic alterations are reversible and specific interventions that target different epigenetic pathways might have a major impact on health problems, eventually providing a new avenue for innovative therapeutic approaches.

nice find.btw cannabinoids have also anti cancer properties and can induce apoptosis which is what isotretinoin does in many types of cell lines.So they(cannabinoids) might induce some unwanted epigenetic changes.Did your genital numbness improve?

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0
(@Anonymous)

Posted : 09/02/2014 3:00 am

Don't know why they removed this page "recently": [Edited link out]

"Successes: no psychiatric registry", i don't know what that mean, maybe they are happy no one finded out the truth? x) Apparently that file proove they already knew about it: [Edited link out]"This is a study by Roche on the effect of isotretinoin on mice. The researchers noted depressive behavior in mice, but this has not been considered important."

Anyway all of that to say they already knew and they don't care so your reports are pretty much useless (i reported it but obv loss of time). You'll have better results tagging every wall on your city with "accutane kills", at least it can prevent some taking it who doesn't know it already x) And there is drugs worse that accutane so even if it's gone, this medical system is still pure crap, pure stupidity with lack of understandment of physiology and the real cause of "diseases".

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18
(@emmyloublood)

Posted : 09/02/2014 3:18 am

I will be taking roaccutane on the 21st of September, 20mg ever other day ( body weight 53kg).

I am keen to know, the people who suffered with side effects and long term effects, what dose were you on?

Obviously reading this thread leaves me with a few worries, however i appreciate that not everyone will have the same experiences.

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MemberMember
153
(@crank92)

Posted : 09/02/2014 7:11 am

On 9/1/2014 at 4:04 PM, Leopold and Stotch said:

Crank:

"An interesting factor and it is why I included the study that showed decreased T and DHT is that while I'm 'high' it is like I'm right back at square one. No libido, impotence and for whatever reason almost complete lack of cremastic reflex (which was reduced after isotretinoin treatment). I seem to experience a 'rebound effect' the next day that last for a couple of weeks once the high sensation wears off."

So you only mobilize a modicum of the negative and degenerative aspects of cannabis temporarily, because the 'negative' ultimately becomes a 'positive' in your estimation. Again, the rhetoric is impeccable. If you couldn't convert the 'negative,' there is little doubt that the readers wouldn't have been treated to it.

Welcome back Monn,

You are correct. I am not the Cochrane review group. I actually committed an even bigger scientific flaw. A more recent and up to date study actually found that chronic cannabis exposure does not cause changes in T.

[Edited link out]

I actually chose the former study as it correlated with my hypothesis. Is that rigorous scientific methodology in action? No, sue me if needs be.

I'm simply trying to find a possible avenue to explain the apparent recoveries through the herb. I'll leave others to study and debate the negative effects. Like any drug it has adverse effects.

Actually, here is an article in The Lancet (excellent journal):

[Edited link out]

General gist = 41% increased risk of psychosis, there were 'substantial confounding factors'. So there is a bit of balance for those interested.

Levianthan, I'll update you in a month or so in regards to RSO. In answer to your question, I would be naive to suggest that it only induces perfect epigenetic changes. So likely yes it will induce some unwanted changes.

On 9/2/2014 at 4:18 PM, emmyloublood said:

I will be taking roaccutane on the 21st of September, 20mg ever other day ( body weight 53kg).

I am keen to know, the people who suffered with side effects and long term effects, what dose were you on?

Obviously reading this thread leaves me with a few worries, however i appreciate that not everyone will have the same experiences.

I took Roaccutane 20mg/day for 10 days in October 2012. Some individuals have experienced severe sides in as little as 2 days which last indefinitely.

I have spoken to individuals who took it back in 1982 when it was released who still suffer side effects.

It is chemotherapy. Remember that.

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1
(@sage1)

Posted : 09/02/2014 8:18 am

I am delighted you were honest about your manipulations, after some light prodding. You should have said: "A more recent and up-to-date study actually found..." That is all, as my brah is watching. We are mourning the passing of Branzino now.

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0
(@Anonymous)

Posted : 09/02/2014 9:16 am

Acne = kidney & lymph congestion, simply as that. Destroying the emunctory (skin) to stop the filtration/acne is highly stupid. Hormonal acne doesn't exist, it's just acids on top of acids (agressive hormones) who can magnify this reaction, not cause it.

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153
(@crank92)

Posted : 09/02/2014 11:33 am

I am delighted you were honest about your manipulations, after some light prodding. You should have said: "A more recent and up-to-date study actually found..." That is all, as my brah is watching.

 

If I didn't accept criticism and change my beliefs based on evidence... I'd probably be religious.

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0
(@moderateacne10years)

Posted : 09/02/2014 2:12 pm

I took Accutane for 6-7 months in December 2010 until May/June 2011 - 40 mg/day. prior to starting Accutane, my doctor didn't seem too worried about side effects, and didn't express that there was a real chance of that happening. When I started I was 26 (31 now) and only had mild/moderate acne. About six months after I finished my course of Accutane, I developed Type 1 Diabetes. After that I had a bunch of other side effects, which include brain fog, dry and itchy skin, joint pain, shoulder surgery to repair torn labrum (which I never even injured, it just sort of started coming out of socket), loss of libido, hair loss, difficulty achieving and maintaining erections. I could deal with all this. But recently, the psychiatric stuff has started and I'm going insane. I have really bad insomnia, which is causing me to be depressed, panic, and have anxiety. I'll be laying in bed, super tired, and I just won't be able to fall asleep. It's like accutane altered my genes and turned something off which normally would allow me to go to sleep. This I can't handle. Has anyone else had this happen? Any ideas on fixing the issue? I'm really scared and could use all the help I can get.

Thanks for reading.

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