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Repairing the long-term damage from Accutane

 
MemberMember
143
(@indigorush)

Posted : 10/12/2013 2:21 pm

It's been a while y'all.

How's things?

Anybody made progress?

My plan:

Lost of rest - mentally and physically.

No more porn.

I'm not convinced that the sexual dysfunction is linked to Accutane anymore.

There's a bunch of guys (young and old) who can't 'perform' in the bedroom with a girl because they've fucked up/de-sensitized their mind with porn.

Also, on the topic of sex, I'm quitting masterbation unless I have a strong urge to erm, beat my meat.

Or jack my beanstalk (I made that one up myself).

With all this recovery, half the battle is mental.

I've learned a lot.

Breathing deeply and allowing yourself to relax helps.

Stress can't be avoided so you have to allow yourself the opportunity to recover, especially with the added worries some of us have had.

Leaving this forum helped me a lot and I barely talk about Accutane anymore.

Because it's boring.. Boring as shit. And nobody else gives a fuck.

So stop going on about it.

Doesn't matter what happened because you can't change it.

Just treat this like any health problem - Give your body the best chance to heal, with good food, good lifestyle choices and make sure to rest when you're tired rather than argue 'I shouldn't be tired this early/this much. I'm only 20', or whatever.

A couple of years ago I was terrified my hair would all turn grey/fall out.

I was scared things would get worse.

Those fears weren't based around facts... just delusions.

Sure.. this drug fucks you up, but I believe we can recover.

Look into 'No Fap' if you're someone who can't get turned on without the stimulation of porn. No Fap actually means no Masturbation too.

Like I said, I'm going to give that a break until my body tells me it's up for it.

A bunch of guys have said there depression/social anxiety and other issues dissolved with No Fap.

Sorry if this seems very random and incoherent after not posting for such a long time, but this is where I'm at right now.

I broke up with my girlfriend about 11 weeks ago (I think) and it's given me the opportunity to better myself and look at my problems objectively.

I'm going to kick these problems out of my life for good this time.

Love y'all x

Quote
MemberMember
223
(@gladiatoro)

Posted : 10/12/2013 6:53 pm

Hey IndigoRush , it's good your making progress , over the years I have come to realize that it's all about symptom management , to be frank that is what it is nothing more nothing less , detox this try that try this etc etc......in the end it is symptom management . And making the best of the situation at hand.

It's been a while y'all.

How's things?

Anybody made progress?

My plan:

Lost of rest - mentally and physically.

No more porn.

I'm not convinced that the sexual dysfunction is linked to Accutane anymore.

There's a bunch of guys (young and old) who can't 'perform' in the bedroom with a girl because they've fucked up/de-sensitized their mind with porn.

Also, on the topic of sex, I'm quitting masterbation unless I have a strong urge to erm, beat my meat.

Or jack my beanstalk (I made that one up myself).

With all this recovery, half the battle is mental.

I've learned a lot.

Breathing deeply and allowing yourself to relax helps.

Stress can't be avoided so you have to allow yourself the opportunity to recover, especially with the added worries some of us have had.

Leaving this forum helped me a lot and I barely talk about Accutane anymore.

Because it's boring.. Boring as shit. And nobody else gives a fuck.

So stop going on about it.

Doesn't matter what happened because you can't change it.

Just treat this like any health problem - Give your body the best chance to heal, with good food, good lifestyle choices and make sure to rest when you're tired rather than argue 'I shouldn't be tired this early/this much. I'm only 20', or whatever.

A couple of years ago I was terrified my hair would all turn grey/fall out.

I was scared things would get worse.

Those fears weren't based around facts... just delusions.

Sure.. this drug fucks you up, but I believe we can recover.

Look into 'No Fap' if you're someone who can't get turned on without the stimulation of porn. No Fap actually means no Masturbation too.

Like I said, I'm going to give that a break until my body tells me it's up for it.

A bunch of guys have said there depression/social anxiety and other issues dissolved with No Fap.

Sorry if this seems very random and incoherent after not posting for such a long time, but this is where I'm at right now.

I broke up with my girlfriend about 11 weeks ago (I think) and it's given me the opportunity to better myself and look at my problems objectively.

I'm going to kick these problems out of my life for good this time.

Love y'all x

Quote
0
(@Anonymous)

Posted : 10/13/2013 5:17 am

I've read that less than 90C is not effective for detoxification.
I've already said it but, for those who still have the side effects of accutane, try the isotherapy after doing some liver flush (7-10), it really work. After the accutane isotherapy i've done an isotherapy for the two antibiotics i took before it (minocycline & doxycycline), it have helped a lot too. I truely can say now that i'm totally fixed from all of the symptoms.

Some quote about mental and diseases:

"Do not repulse the issue, refuse it, as if we do not accept responsibility or we will create subconscious impulses and sends a signal to the body not to send "healing agents" of oxygen, blood flow in the impacted areas."

All thoughts and feelings are instantly translated into biochemical compounds within the brain and within every other part of the body, thereby altering physical appearance and performance. In fact, every bit of mental activity leaves us with a specific physical sensation, known as emotion. Emotions are composites of both mental impulses and physical changes, and they express the totality of ones health at any given time.
Carefully controlled studies have shown that you can reduce your biological age by 10-15 years within ten days, provided your interpretation of your life experience undergoes rapid and positive changes. By contrast, you can also put on 20 extra years within a single day if you enter a state of hopelessness and depression. Hormones produce extremely powerful effects, both in a positive and negative sense. Yet even more powerful than hormones are the thoughts and intentions that trigger them.
New brain research has even gone so far as to claim that whether we heal, or dont heal, from a disease has nothing at all to do with taking medications, but is entirely due to a patients expectation.i So far, medical treatment was believed to be the only determining factor behind the cure or recovery from a particular disease. This new research completely invalidates that theory. So what can you do with this information?

I wish to mention at this point that according to dozens of scientific studies, secretions of the DNAs powerful anticancer hormone, interleukin II, drop under physical and mental duress and increase again when the person becomes relaxed and joyful. The research data clearly reveals the mechanism whereby the central nervous system modulates gene expression and the immune response during psychological stress. Thus, stress has been shown to lower secretions of Interleukin II and thereby increase the incidence of cancer in the body; on the other hand, normal secretion of this hormone keeps cancer at bay. The same has been shown with regard to Interferon, another very powerful hormone that cells secrete to remain cancer-free. This further proves that stress can afflict wounds and by interfering with the hormone-secreting ability of cells allow the bodys wound healing program, that is, cancer, do its life-saving work.

Quote
MemberMember
85
(@and1)

Posted : 10/13/2013 5:36 am

I've read that less than 90C is not effective for detoxification.

I've already said it but, for those who still have the side effects of accutane, try the isotherapy after doing some liver flush (7-10), it really work. After the accutane isotherapy i've done an isotherapy for the two antibiotics i took before it (minocycline & doxycycline), it have helped a lot too. I truely can say now that i'm totally fixed from all of the symptoms.

I have read a couple of books lately which touched in detail on how the topic of detox and they always recommended saunas with temperatures of 60-70C, check what Mark Hyman or Terry Grossman write on the topic. This is also the temerpature used in most studies and coincides with my own experience. The sauna I go to has a temperature of 90 to 95 C on the top level. Initially I started out on the top bench and I would frequently get sick after visiting the sauna, or feel devastated for longer periods of time after having visited the sauna. I have not had any problems eversince switching to the lower level where the temperature is far lower.

I have done liver flushing in the past and it has helped me a great deal. I will start flushing again before the year is over. Most people are very wary of liver flushing until they have tried it. They are willing to try dangerous drugs before trying flushing it is ridiculous. By the way I would assume that liver flushing also speeds up the metabolism of the organs, as EPSOM salt stimulates blood circulation and raises body temperature when bathing in it.

Quote
MemberMember
223
(@gladiatoro)

Posted : 10/13/2013 8:43 am

 

I've read that less than 90C is not effective for detoxification.

I've already said it but, for those who still have the side effects of accutane, try the isotherapy after doing some liver flush (7-10), it really work. After the accutane isotherapy i've done an isotherapy for the two antibiotics i took before it (minocycline & doxycycline), it have helped a lot too. I truely can say now that i'm totally fixed from all of the symptoms.

I have read a couple of books lately which touched in detail on how the topic of detox and they always recommended saunas with temperatures of 60-70C, check what Mark Hyman or Terry Grossman write on the topic. This is also the temerpature used in most studies and coincides with my own experience. The sauna I go to has a temperature of 90 to 95 C on the top level. Initially I started out on the top bench and I would frequently get sick after visiting the sauna, or feel devastated for longer periods of time after having visited the sauna. I have not had any problems eversince switching to the lower level where the temperature is far lower.

I have done liver flushing in the past and it has helped me a great deal. I will start flushing again before the year is over. Most people are very wary of liver flushing until they have tried it. They are willing to try dangerous drugs before trying flushing it is ridiculous. By the way I would assume that liver flushing also speeds up the metabolism of the organs, as EPSOM salt stimulates blood circulation and raises body temperature when bathing in it.

Indigor Rush took saunas as I remember but the chronic systemic dehydration persisted ,I bought a infared sauna and proceeded to use it I years ago and it was too hot and I think I was in there too long and I felt sick for a while after it was like a re-activation of symptoms for me so I would suggest CAUTION with saunas especially infared ones as they penetrate the skin 3 inches . Lower temperatures yes , less time in the sauna if it helps you great but like I said go easy on it. One Derm I read described Isotretinoin for what it is a controlled POISONING , that is in FACT what it truely is.

It's a CUT , POISON , BURN approach typical allopathic medicine , like I said symptom management and until you guys realize this there wil be no progress made on this forum , some things help yes but it is what it is a CHRONIC CONDITION .

Quote
MemberMember
85
(@and1)

Posted : 10/13/2013 1:46 pm

Well, I don't use infrared sauna, I use a regular finnish sauna. From what I have read there exist different kinds of infrared systems, but I am not familiar with the use of infrared sauna and probably would not do it unless supervised by a doc.

At the same time as I started sauna, I began treating my skin almost daily with a mix of olive oil (80%) and a facial skincare cream for infants (20%). The immediate result - within 5 days - was normalised hydration of the skin, you know it is glowing, like it is supposed to be. However, it is too early to tell whether these effects will sustain after decreasing the frequency of the sauna use and application of skincare products/olive oil.

From what I have read regular russian/finnish saunas have been used in the mining industry before our time to detox miners from the exposure to heavy metals, definitely worth a try.

 

I've read that less than 90C is not effective for detoxification.
I've already said it but, for those who still have the side effects of accutane, try the isotherapy after doing some liver flush (7-10), it really work. After the accutane isotherapy i've done an isotherapy for the two antibiotics i took before it (minocycline & doxycycline), it have helped a lot too. I truely can say now that i'm totally fixed from all of the symptoms.

I have read a couple of books lately which touched in detail on how the topic of detox and they always recommended saunas with temperatures of 60-70C, check what Mark Hyman or Terry Grossman write on the topic. This is also the temerpature used in most studies and coincides with my own experience. The sauna I go to has a temperature of 90 to 95 C on the top level. Initially I started out on the top bench and I would frequently get sick after visiting the sauna, or feel devastated for longer periods of time after having visited the sauna. I have not had any problems eversince switching to the lower level where the temperature is far lower.

I have done liver flushing in the past and it has helped me a great deal. I will start flushing again before the year is over. Most people are very wary of liver flushing until they have tried it. They are willing to try dangerous drugs before trying flushing it is ridiculous. By the way I would assume that liver flushing also speeds up the metabolism of the organs, as EPSOM salt stimulates blood circulation and raises body temperature when bathing in it.

Indigor Rush took saunas as I remember but the chronic systemic dehydration persisted ,I bought a infared sauna and proceeded to use it I years ago and it was too hot and I think I was in there too long and I felt sick for a while after it was like a re-activation of symptoms for me so I would suggest CAUTION with saunas especially infared ones as they penetrate the skin 3 inches . Lower temperatures yes , less time in the sauna if it helps you great but like I said go easy on it. One Derm I read described Isotretinoin for what it is a controlled POISONING , that is in FACT what it truely is.

It's a CUT , POISON , BURN approach typical allopathic medicine , like I said symptom management and until you guys realize this there wil be no progress made on this forum , some things help yes but it is what it is a CHRONIC CONDITION .

Indigo had some sauna kit to use at home, it looked very suspicious to me. I really can't see how you can properly take saunas without using a wooden cabin.

Also do you remember a single thing that worked for Indigo? I recall that nothing worked for him the slightest.

Quote
MemberMember
223
(@gladiatoro)

Posted : 10/13/2013 2:47 pm

Well, I don't use infrared sauna, I use a regular Finnish sauna. From what I have read there exist different kinds of infrared systems, but I am not familiar with the use of infrared sauna and probably would not do it unless supervised by a doc.

At the same time as I started sauna, I began treating my skin almost daily with a mix of olive oil (80%) and a facial skincare cream for infants (20%). The immediate result - within 5 days - was normalized hydration of the skin, you know it is glowing, like it is supposed to be. However, it is too early to tell whether these effects will sustain after decreasing the frequency of the sauna use and application of skincare products/olive oil.

From what I have read regular Russian/Finnish saunas have been used in the mining industry before our time to detox miners from the exposure to heavy metals, definitely worth a try.

 

I've read that less than 90C is not effective for detoxification.

I've already said it but, for those who still have the side effects of accutane, try the isotherapy after doing some liver flush (7-10), it really work. After the accutane isotherapy i've done an isotherapy for the two antibiotics i took before it (minocycline & doxycycline), it have helped a lot too. I truely can say now that I'm totally fixed from all of the symptoms.

I have read a couple of books lately which touched in detail on how the topic of detox and they always recommended saunas with temperatures of 60-70C, check what Mark Hyman or Terry Grossman write on the topic. This is also the temperature used in most studies and coincides with my own experience. The sauna I go to has a temperature of 90 to 95 C on the top level. Initially I started out on the top bench and I would frequently get sick after visiting the sauna, or feel devastated for longer periods of time after having visited the sauna. I have not had any problems ever since switching to the lower level where the temperature is far lower.

I have done liver flushing in the past and it has helped me a great deal. I will start flushing again before the year is over. Most people are very wary of liver flushing until they have tried it. They are willing to try dangerous drugs before trying flushing it is ridiculous. By the way I would assume that liver flushing also speeds up the metabolism of the organs, as EPSOM salt stimulates blood circulation and raises body temperature when bathing in it.

Indigor Rush took saunas as I remember but the chronic systemic dehydration persisted ,I bought a infared sauna and proceeded to use it I years ago and it was too hot and I think I was in there too long and I felt sick for a while after it was like a re-activation of symptoms for me so I would suggest CAUTION with saunas especially infared ones as they penetrate the skin 3 inches . Lower temperatures yes , less time in the sauna if it helps you great but like I said go easy on it. One Derm I read described Isotretinoin for what it is a controlled POISONING , that is in FACT what it truly is.

It's a CUT , POISON , BURN approach typical allopathic medicine , like I said symptom management and until you guys realize this there wil be no progress made on this forum , some things help yes but it is what it is a CHRONIC CONDITION .

Indigo had some sauna kit to use at home, it looked very suspicious to me. I really can't see how you can properly take saunas without using a wooden cabin.

Also do you remember a single thing that worked for Indigo? I recall that nothing worked for him the slightest.

Definitely stay away from infared saunas I gave mine to my brother after spending 3 k on it , it is way too potent a Russian/finish sauna is different it is used with a moisture application usually pored on the coals or something to that order I can see benefits there , when I work in the sun I have no problems with sweating etc..

But again use caution excessive heat may detox too much and cause problems. Your right nothing worked for indigo as I recall in fact like me I tried a few

things like stinging nettle/saw palmetto and found it to be of negative consequences , what does work to is plenty of rest , no alcohol and a balanced diet not overloaded with carbs and junk food. Sadly some of these herbal mixtures are actually detrimental to us dht blockers / anti androgens best to stay clear of.

I have a friend who is from Finland there they use saunas all the time he built his own he knows how obviously it's a steam style may be worth looking into.

Quote
MemberMember
85
(@and1)

Posted : 10/13/2013 3:55 pm

 

Well, I don't use infrared sauna, I use a regular Finnish sauna. From what I have read there exist different kinds of infrared systems, but I am not familiar with the use of infrared sauna and probably would not do it unless supervised by a doc.

At the same time as I started sauna, I began treating my skin almost daily with a mix of olive oil (80%) and a facial skincare cream for infants (20%). The immediate result - within 5 days - was normalized hydration of the skin, you know it is glowing, like it is supposed to be. However, it is too early to tell whether these effects will sustain after decreasing the frequency of the sauna use and application of skincare products/olive oil.

From what I have read regular Russian/Finnish saunas have been used in the mining industry before our time to detox miners from the exposure to heavy metals, definitely worth a try.

 

I've read that less than 90C is not effective for detoxification.

I've already said it but, for those who still have the side effects of accutane, try the isotherapy after doing some liver flush (7-10), it really work. After the accutane isotherapy i've done an isotherapy for the two antibiotics i took before it (minocycline & doxycycline), it have helped a lot too. I truely can say now that I'm totally fixed from all of the symptoms.

I have read a couple of books lately which touched in detail on how the topic of detox and they always recommended saunas with temperatures of 60-70C, check what Mark Hyman or Terry Grossman write on the topic. This is also the temperature used in most studies and coincides with my own experience. The sauna I go to has a temperature of 90 to 95 C on the top level. Initially I started out on the top bench and I would frequently get sick after visiting the sauna, or feel devastated for longer periods of time after having visited the sauna. I have not had any problems ever since switching to the lower level where the temperature is far lower.

I have done liver flushing in the past and it has helped me a great deal. I will start flushing again before the year is over. Most people are very wary of liver flushing until they have tried it. They are willing to try dangerous drugs before trying flushing it is ridiculous. By the way I would assume that liver flushing also speeds up the metabolism of the organs, as EPSOM salt stimulates blood circulation and raises body temperature when bathing in it.

Indigor Rush took saunas as I remember but the chronic systemic dehydration persisted ,I bought a infared sauna and proceeded to use it I years ago and it was too hot and I think I was in there too long and I felt sick for a while after it was like a re-activation of symptoms for me so I would suggest CAUTION with saunas especially infared ones as they penetrate the skin 3 inches . Lower temperatures yes , less time in the sauna if it helps you great but like I said go easy on it. One Derm I read described Isotretinoin for what it is a controlled POISONING , that is in FACT what it truly is.

It's a CUT , POISON , BURN approach typical allopathic medicine , like I said symptom management and until you guys realize this there wil be no progress made on this forum , some things help yes but it is what it is a CHRONIC CONDITION .

Indigo had some sauna kit to use at home, it looked very suspicious to me. I really can't see how you can properly take saunas without using a wooden cabin.

Also do you remember a single thing that worked for Indigo? I recall that nothing worked for him the slightest.

Definitely stay away from infared saunas I gave mine to my brother after spending 3 k on it , it is way too potent a Russian/finish sauna is different it is used with a moisture application usually pored on the coals or something to that order I can see benefits there , when I work in the sun I have no problems with sweating etc..

But again use caution excessive heat may detox too much and cause problems. Your right nothing worked for indigo as I recall in fact like me I tried a few

things like stinging nettle/saw palmetto and found it to be of negative consequences , what does work to is plenty of rest , no alcohol and a balanced diet not overloaded with carbs and junk food. Sadly some of these herbal mixtures are actually detrimental to us dht blockers / anti androgens best to stay clear of.

I have a friend who is from Finland there they use saunas all the time he built his own he knows how obviously it's a steam style may be worth looking into.

Where I am from saunas are very popular too. Let me tell you the finnish sauna is a dry sauna actually, but read up on it yourself on wikipedia.

Quote
MemberMember
85
(@and1)

Posted : 10/14/2013 1:53 am

I know, here it is used mostly dry, every 30 to 60 minutes they pour something over the rocks to generate steam and the sensation of heat, but it drys up quickly.

Quote
MemberMember
66
(@jtm88)

Posted : 10/14/2013 10:37 am

Be very careful with Saunas.

Our bodies are already dehydrated. The heat from Saunas can dry you out even more. Normally, you can replenish by drinking tons of water. But our cells can't seem to hold water as well as before. Whatever we drink, we pee right out.

Also, the heat my further exacerbate inflammation and cause further problems with your stomach mucous membrane.

Exercise is still the best way.

I know, here it used mostly dry, every 30 to 60 minutes they pour something over the rocks to generate steam and the sensation of heat, but it drys up quickly.

Quote
MemberMember
85
(@and1)

Posted : 10/14/2013 11:38 am

I know there are considerable differences between the sweating caused by exercise and sauna, but none of you guys has tried it hardcore like I have, but everybody is like be careful.

Quote
MemberMember
66
(@jtm88)

Posted : 10/14/2013 12:17 pm

I tried it for a week. When to my local gym. 15 mins of exercise followed by 10 mins in the Sauna.

Always had a burning sensation with my stomach while in the Sauna. Eyes also became blood red. All these lasted for a few days after the last sauna session.

Could just be my personal experience though.

I know there are considerable differences between the sweating caused by exercise and sauna, but none of you guys has tried it hardcore like I have, but everybody is like be careful.

Quote
MemberMember
85
(@and1)

Posted : 10/14/2013 2:05 pm

 

I tried it for a week. When to my local gym. 15 mins of exercise followed by 10 mins in the Sauna.

Always had a burning sensation with my stomach while in the Sauna. Eyes also became blood red. All these lasted for a few days after the last sauna session.

Could just be my personal experience though.

I know there are considerable differences between the sweating caused by exercise and sauna, but none of you guys has tried it hardcore like I have, but everybody is like be careful.

Well, Ok then I take that back. The sauna must have been to hot for, as I said before I have read time and time again that if you have a toxic laden body you got to stick to low temperatures of around 60 degrees celcius. If you have trouble getting used to going to the sauna make also make sure that you lie down while staying in the sauna, so that your whole body is exposed to the same temperature.

My eyes also become bloodshot, but it has lessened over time considerably. With me the blodshot eyes fade within 15 minutes or so after I leave the sauna.

Quote
MemberMember
223
(@gladiatoro)

Posted : 10/14/2013 3:04 pm

 

I tried it for a week. When to my local gym. 15 mins of exercise followed by 10 mins in the Sauna.

Always had a burning sensation with my stomach while in the Sauna. Eyes also became blood red. All these lasted for a few days after the last sauna session.

Could just be my personal experience though.

I know there are considerable differences between the sweating caused by exercise and sauna, but none of you guys has tried it hardcore like I have, but everybody is like be careful.

It's a form of re-activation is what it is , there is no question our DNA has been permanently changed , I think that is all that's happening and frankly I don't think that's a good idea to use a sauna if you feel sick and have stomach problems/red eyes . Since our skin cell receptors are ^&*( up , I think it's best not to play around and worsen symptoms. I have found I do the best if I don't play with my skin in any way I call it poison level control took me years to figure this out but it's true. Also watch your diet high levels of vit A /retinol are not good for us , basically our whole system has been ^&*( over . We all know about dht blockers / anti adrogens , it's quite a complicated poisoning actually .

Quote
MemberMember
5
(@sunnyhatesacne)

Posted : 10/15/2013 10:30 am

 

I tried it for a week. When to my local gym. 15 mins of exercise followed by 10 mins in the Sauna.

Always had a burning sensation with my stomach while in the Sauna. Eyes also became blood red. All these lasted for a few days after the last sauna session.

Could just be my personal experience though.

I know there are considerable differences between the sweating caused by exercise and sauna, but none of you guys has tried it hardcore like I have, but everybody is like be careful.

It's a form of re-activation is what it is , there is no question our DNA has been permanently changed , I think that is all that's happening and frankly I don't think that's a good idea to use a sauna if you feel sick and have stomach problems/red eyes . Since our skin cell receptors are ^&*( up , I think it's best not to play around and worsen symptoms. I have found I do the best if I don't play with my skin in any way I call it poison level control took me years to figure this out but it's true. Also watch your diet high levels of vit A /retinol are not good for us , basically our whole system has been ^&*( over . We all know about dht blockers / anti adrogens , it's quite a complicated poisoning actually .

Hi Gladiatoro I would like apologize to you before saying this ... Don't get me wrong but your thoughts seems very pessimist.. We know that all of us had an adverse reaction to the drug but that doesn't mean we should give up hope...

The body does what the mind commands... I don't if you know but there has been studies on the placebo effect where they give patients fake drug and surprisingly the body recovers from that illness... So, we got to be positive and believe that we can get rid of this drug for sure..

http://en.wikipedia.org/wiki/Placebo_effect

I am grateful that we all are here and dealing with the similar symptoms and trying to brain storm different ideas on how to get rid of the Accutane..

Quote
MemberMember
5
(@sunnyhatesacne)

Posted : 10/15/2013 11:34 am

 

Lose of Night Vision is mostly likely due to excessive drying of the hyaluronic acid in your eyes.

Highly unlikely Accutane causes Vitamin A deficiency. All evidence from doctors, biochemists, indicate that Accutane is very similar to Vitamin A. Also, most of us eat lots of vegetables as we are trying to fix our bodies. So shoudnt have Vitamin A deficiency.

Digestion 101 on Fat and it's effect on Liver / Accutane

Digestion 101:

The fat digestion starts when we start consuming the food in the mouth.. The Lipase enzyme starts working on the fatty food in our mouth.. The fatty food is hydrophobic so it doesn't get absorbed in the stomach.. When the liver senses the fatty food it triggers the secretion of bile acid which is released from the gall bladder. The bile acid emulsifies the fatty acid (triglycerides) and then it moves to the small intestine . Small intestine has large no of villi which help to break the emulsified fat which go to the blood stream and is absorbed by cells.. The emulsified fatty acid is converted back into the bile acid and is restored into the gallbladder. This process is called Enterohepatic circulation.

http://en.wikipedia.org/wiki/Enterohepatic_circulation

Accutane:

Accutane in reality is nothing but fat that we are consuming.. So, what happens is that when we consume lot of Vitamin A.. It is absorbed and stored in to our liver..

- Excessive vitamin A in liver --> Bile acid have Vitamin A --> IBS

- Excessive Vitamin A in liver --> Excessive Vitamin A in cells --> Dry skin

- Excessive Vitamin A in liver --> Excessive Vitamin in A in hair --> loss of hair

- Excessive Vitamin A in liver --> Less Vitamin D as they compete ---> Bone loss as calcium absorption depends on Vitamin D, Muscle pain

-Excessive Vitamin A in liver --> Less Vitamin E as they compete ---> Less oxidation and muscle pain.

The problem is that since our body has a very good Enterohepatic circulation . The fat is re-circulated in our body very well and we can't really help with it...

Solution I think will work:

-- Consuming a balanced fat ( Coconut oil/ Seasame oil/ Oliver oil/ Ghee) like we did for Acccutane.. It should be consumed early morning as liver is most active in early morning.

-- Consuming the foods that increase the bile acid production

http://www.livestrong.com/article/535096-foods-that-increase-bile-flow/

-- Consuming the foods that help to break the Enterohepatic Circulation by binding the fat into the stool.

http://en.wikipedia.org/wiki/Bile_acid_sequestrant

The natural foods that are rich in binding the fat are natural fibres like psyllium husk, prune juice...

Disclaimer : Remember all these things addition to your diet will initially load the liver so we need to take easy on our liver during this time.. Like the same precaution to follow what we followed when we were on Accutane like no drinking alchoal, rise of cholesterol, higher lipid profile tests as liver is working really hard.

Let me know what do u think about it?

That all sounds great only problem is that ACCUTANE ISN'T VITAMIN A , it's a SYNTHETIC DRUG and acts totally different than a natural form of vit A ,

even ROCHE states we don't know the mechanism behind isotretinoin , but as I have said before I bet they do....

Accutane is not vitamin A. The body handles it differently from natural vitamin A (see Figure 4) and there are a number of lines of evidence showing that it acts as an anti-vitamin A compound that can aggravate vitamin A deficiency. In newborn mice treated with dexamethasone, a drug that induces emphysema-like changes to lung tissue, natural vitamin A helps treat the disorder while the active ingredient of Accutane has no effect and may even make it worse.30 Accutane caused night blindness, a traditional sign of vitamin A deficiency, in a child with cystic fibrosis, whereas vitamin A supplementation resolved the night blindness.31 In rats, the active ingredient of this drug accumulates in the eyes and interferes with vitamin A recycling; rats taking it at high doses took fifty times longer to recover from exposure to intense light than rats that did not take the drug at all.32

A physician published a letter earlier this year reporting that two patients developed depression on Accutane; when the physician took them off the drug and supplemented them with 10-12,000 IU of vitamin A for seven to ten days, the depression resolved and they were able to go back on the drug without it recurring.33 The totality of the evidence strongly suggests that vitamin A deficiency contributes to depression and that Accutane is associated with this mental illness because it interferes with vitamin A metabolism.

Ironically, in order to understand the connection of vitamin D with mental health, we must examine the next criticism levied against vitamin A.

Vitamin D and Eskimo Hysteria

Recent reviews reference a 1985 paper arguing that the high intake of vitamin A among the Arctic Inuit was responsible for a phenomenon of hysteria that they called pibloktoq.34 This disorder involves several days of irritability or withdrawal, a sudden excitation wherein the victim flees the camp and engages in irrational and dangerous behavior, convulsive seizures, a twelve-hour period of coma or stuporous sleep, and a return to normal. The author offers the following lines of evidence supporting a tie to vitamin A toxicity: the Inuit consider polar bear liver, which is the richest source of vitamin A, to be toxic; explorers who eat polar bear liver out of necessity experience drowsiness, irritability, headaches, and nausea within hours of consuming it; and case reports of vitamin A toxicity involve irritability, drowsiness, double vision and anorexia.

Even within this paper the author mentions numerous facts that make this hypothesis problematic. The specific symptoms of pibloktoq are limited to the Arctic and Antarctic and tend to occur in the late winter and early spring. There is no compelling explanation for why vitamin A toxicity would fall within these geographical and seasonal restrictions. The Inuit consider polar bear liver safe as long as the membrane is removed and consider seal liver, which contains half as much vitamin A, safe to eat in unlimited quantities. If vitamin A were the toxic component of polar bear liver, the cultural prohibition against eating the membrane would therefore be useless. Finally, vitamin A toxicity generally accompanies chronically high intakes over time, usually of chemically altered supplemental forms, whereas the hysterical episodes found among the Inuit are acute and sporadic.

In 1972, another author offered a much better hypothesis tying the episodes to hypocalcemic tetany, a disorder of involuntary muscle contractions accompanying severe deficiencies of calcium and vitamin D.35 The muscle contractions occur because the peripheral nerves cannot regulate their impulses in the absence of calcium. The disorder is often accompanied by œemotional and cognitive disorganization and convulsive seizures, probably resulting from the absence of calcium in the central nervous system. Like pibloktoq, episodes are acute and sporadic.

Populations that inhabit areas of the Arctic where fishing is limited or the weather is unsuitable for drying fish”the primary source of vitamin D and calcium in the Inuit diet”have high rates of tetany in infants and muscle cramps, a related symptom, in adults. The bone disease rickets, by contrast, is extremely rare, suggesting that in the physically demanding environment of the Arctic, the Inuit have adapted by giving skeletal development priority over the nervous system. The Inuit have inherited numerous cultural adaptations centered on providing sufficient calcium and vitamin D to the members of their groups, especially to pregnant and lactating women, reinforcing the concept that vitamin D and calcium are periodically limiting factors for good health in these populations.

If we are to investigate the mechanism by which vitamin D may be involved in this illness, we should look first of all to its primary function”maintaining calcium status. One compelling explanation for how vitamin D may prevent the convulsive seizures associated with hypocalcemic tetany and pibloktoq is that it supplies the calcium necessary for the production of endocannabinoids. The marijuana derivative hashish has been used since at least the fifteenth century to treat epilepsy. More recent research has shown that the endocannabinoids named after this drug are powerful inhibitors of glutamate toxicity and many other seizure-promoting excitotoxins. Boosting their levels in the brain helps prevent the experimental induction of seizures, while depleting or antagonizing them lowers the amount of drugs necessary to induce seizures.36

The production of endocannabinoids from arachidonic acid is critically dependent on the supply of calcium since it is the influx of this mineral into the cell that turns on the enzymes responsible for this conversion.17 At a minimum, vitamin D is required to supply sufficient calcium to the brain in order for this influx to take place. Since some cells use vitamin D as a signal to open calcium channels and allow a rapid influx of calcium,19 it is possible that brain cells require vitamin D for endocannabinoid production in this way as well.

One more research that I did and i would like to share with you guys that I have been doing on the Accutane... It is really interesting that the more I study the more i feel that I don't know anything.. I would like to revise my initial assessement that I did for the Accutane:

What is Accutane?

-- Accutane is synthetic form of Vitamin A.. The body needs Vitamin A for different types functions of the body like growth, immunity against diseases, good vision.. When we take foods rich in Vitamin A the body converts these into different retinol through different enzymes.. The body maintains homeostasis for these different retinoids in our body.

http://en.wikipedia.org/wiki/Human_homeostasis

So, in nutshell Vitamin A is not Vitamin A but a bunch of different retinols which are required for the normal functioning of the body. The body can convert the plant food sources to retinols but the reverse is not possible.

The body requires different retinols for eg. (11 cis)-retinoic acid is required for the eye sights.. (13cis)-retinoic acid is the retinol for the Accutane..

How accutane is stored in our body?

Unfortunately the body has no way of converting back the retinols so it get's stored in our liver (50-80% of it) and rest of it get's stored in the fatty cells of our body which may be skin (clear /dry skin) , in the hair (cause hair loss), in the muscles (weak muscles), in the stomach (IBS) , in the eyes ( dry eyes)..

So, the effect of clearing up our skin is due to the overloading of (13 cis) -retinoic acid in our body.

Retinoid excretion from the body ?

So, the main idea for the removal involves removing this excess retinol from the liver.. The liver detoxifies involves converting this retinoid into the water soluble form.

Xenobiotic_metabolism.png

This is a two step process and involves two things :

1. Phase 1 Oxidation (Mediated by P-450 enzymes) : In the oxidation one of the most common modifications is hydroxylation catalysed by the cytochrome P-450-dependent mixed-function oxidase system. These enzyme complexes act to incorporate an atom of oxygen into nonactivated hydrocarbons, which can result in either the introduction of hydroxyl groups With oxidation even a small amount of the

2. Phase 2 Conjugation (Mediated by Glucuronidation) : In subsequent phase II reactions, these activated xenobiotic metabolites are conjugated with charged species such as glutathione (GSH), sulfate, glycine, or glucuronic acid . For retinoids this should happen with glucuronic acid. The hydrolysed active components are converted into water soluble components which can be excreted by our urine or through stool

3. Phase 3 Removal from body : Involves removal of the water soluble components for body through the excretion of urine or stool.

For more information you can go over some of the research paper that show how 13-cis-retionic acid is excreted from our system.

http://dmd.aspetjournals.org/content/38/7/1211.full

This is a research paper published in year 2010 showing how we can do UDP-Glucuronosyltransferase ( Phase -2 ) for removal of retinoid (13-cis-retionic acid) from body.

lease guys go over it and let me know what do you think about it.

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and1, and1 and and1 reacted
MemberMember
223
(@gladiatoro)

Posted : 10/15/2013 12:03 pm

 

I tried it for a week. When to my local gym. 15 mins of exercise followed by 10 mins in the Sauna.

Always had a burning sensation with my stomach while in the Sauna. Eyes also became blood red. All these lasted for a few days after the last sauna session.

Could just be my personal experience though.

I know there are considerable differences between the sweating caused by exercise and sauna, but none of you guys has tried it hardcore like I have, but everybody is like be careful.

It's a form of re-activation is what it is , there is no question our DNA has been permanently changed , I think that is all that's happening and frankly I don't think that's a good idea to use a sauna if you feel sick and have stomach problems/red eyes . Since our skin cell receptors are ^&*( up , I think it's best not to play around and worsen symptoms. I have found I do the best if I don't play with my skin in any way I call it poison level control took me years to figure this out but it's true. Also watch your diet high levels of vit A /retinol are not good for us , basically our whole system has been ^&*( over . We all know about dht blockers / anti adrogens , it's quite a complicated poisoning actually .

Hi Gladiatoro I would like apologize to you before saying this ... Don't get me wrong but your thoughts seems very pessimist.. We know that all of us had an adverse reaction to the drug but that doesn't mean we should give up hope...

The body does what the mind commands... I don't if you know but there has been studies on the placebo effect where they give patients fake drug and surprisingly the body recovers from that illness... So, we got to be positive and believe that we can get rid of this drug for sure..

http://en.wikipedia.org/wiki/Placebo_effect

I am grateful that we all are here and dealing with the similar symptoms and trying to brain storm different ideas on how to get rid of the Accutane..

Sorry I get moody it's a side effect lol...

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MemberMember
1
(@johndavid22)

Posted : 10/15/2013 3:47 pm

hello,

i am a post finasteride user dealing with similar side effects to you guys. this stuff sucks, doesn't it?

i know one guy here managed to use CANNOBIS OIL to cure himself of the post accutane symptoms. i am lucky to live in a state where I can get my hands on it and I will be giving it a go, but I wanted to ask, has anyone else TRIED CANNOBIS OIL?

successful or unsuccessful, has anyone else done it? no one on propeciahelp.com has done it. i want to know if anyone else has tried it?

thank you.

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MemberMember
223
(@gladiatoro)

Posted : 10/15/2013 8:01 pm

Let us know if it works , make sure to use pure grade oil.

hello,

i am a post finasteride user dealing with similar side effects to you guys. this stuff sucks, doesn't it?

i know one guy here managed to use CANNOBIS OIL to cure himself of the post accutane symptoms. i am lucky to live in a state where I can get my hands on it and I will be giving it a go, but I wanted to ask, has anyone else TRIED CANNOBIS OIL?

successful or unsuccessful, has anyone else done it? no one on propeciahelp.com has done it. i want to know if anyone else has tried it?

thank you.

Quote
MemberMember
1
(@johndavid22)

Posted : 10/15/2013 8:39 pm

 

Let us know if it works , make sure to use pure grade oil.

hello,

i am a post finasteride user dealing with similar side effects to you guys. this stuff sucks, doesn't it?

i know one guy here managed to use CANNOBIS OIL to cure himself of the post accutane symptoms. i am lucky to live in a state where I can get my hands on it and I will be giving it a go, but I wanted to ask, has anyone else TRIED CANNOBIS OIL?

successful or unsuccessful, has anyone else done it? no one on propeciahelp.com has done it. i want to know if anyone else has tried it?

thank you.

yeah i'm going to get this stuff called Charlotte's Web cannabis oil. It's one of the most potent ones. i sent my app in almost a month ago, but i know they are going through it now. i should be getting the red card hopefully in the next week or two.

right now i'm doing really heavy diet stuff and doing a few other things that are getting me CLOSE to getting back to baseline, i'm really hoping the cannabis oil will be the final shove over the edge. will keep you guys updated though.

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MemberMember
85
(@and1)

Posted : 10/16/2013 2:50 am

Anybody know what happened to Joseph?

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MemberMember
5
(@sunnyhatesacne)

Posted : 10/16/2013 11:38 am

 

Guys are you serious. I've already told you how to flush out this accutane.

 

Accutane is expelled via the bile, the best thing to expell all the bile without reabsorption is the liver flush by andreas moritz.

You do 6-10 liver flush, 1-2 kidney cleanse and then you do the homeopathic isotherapy like this (i did it in the morning, 30 min before eating) day 1: 30K, day 3: 200K, day 5: XM, day 7: XMK.

 

While doing this isotherapy you need to take 7+day fermented kombucha (who potentially contain udp-glucuronic acid & glucaric acid) + 1 supplement of calcium-d-glucarate (1-2gr 3times per day) + food (artichoke) or supplement (chondroitin, artichoke extract) who contain glucuronic acid (facultative) + a lot of fiber (eat only fruit & vegs**), we can add: psyllium, bentonite, charcoal to prevent reabsorption. This isotherapy isn't easy cause it will bring all the symptoms back for 1-3 weeks but it will be fucking magical to get your old body back smile.png

 

** I've took 20ml of olive oil + 20ml lemon juice after eat some fruits and psyllium+bentonite+charcoal to expell all the bile every morning.

 

PS: I think it's a good idea to have a good stock of real vitamin A & vitamin D (from sun exposure) before doing the isotherapy, that's what i did, i've eat some carrots & took red ice skate liver oil.

I don't know if it's matter but i've took nux vomica (at the same dosage) 10min after the isotherapic isotretinoin.

Great to hear this worked! Can you explain it more in a step-wise way? Did you do the liver flush for X number of days, then the kidney flush, then 7 days of isotherapy? What can and can't you eat on the isotherapy?

I can't tell if i did it the best way but i did first one kidney flush (3week) and then 10 liver flush. the next day of the 10th flush i started the isotherapy.

I avoided dairy & gluten and took only a little bit of chicken & eggs (only cook with water to not oxyde the cholesterol). best thing is to eat only fruit & vegetables.

For the olive oil + citrus in the morning it's really your choice for the method, cause the isotherapy work for 6weeks so you can do it only 1/2 week or only with low dose everyday or every two day, i took a dose who doesnt cause fatigue for me.

For the calcium-d-glucarate it's better to only take 500mg 2 or 3times i think, when i took more i was a little bit tired.

Hi Annoyy I have also started taking Calcium d glucrate but for some reason the first 2 day i took it i got really terrible migrane headaches.. Now the headaches are gone but still they make feel very sleepy and tired ... It is really annoying that sometimes i feel full of energy .. The sex drives increases so much, the muscle pain goes away and then in couple of hours i feel so sleepy and tired again...

I started off with 500 mg daily and is trying to progress to 750 mg but it is making me feel very tired.. do you have any ideas on how i can increase my intake ? Also, how long you took it?

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0
(@Anonymous)

Posted : 10/16/2013 11:53 am

Don't take too much it makes me feel tired and possibly some light headache too. I took 1 or 2gr per day for 2weeks but it was a bad idea, it was too much. 500mg seems fine. But kombucha (7+ day fermented, 14 best) is more important than this d-glucarate. Both combined is perfect. I added too globe artichoke & beetroot each day or too day, artichoke for the glucuronic acid.
kombucha potentially contain directly udp-glucuronic acid

[Edited link out]
glucuronic acid & joints: [Edited link out]

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MemberMember
223
(@gladiatoro)

Posted : 10/16/2013 1:12 pm

How many mg did you take of isotretinoin ?

 

Guys are you serious. I've already told you how to flush out this accutane.

Accutane is expelled via the bile, the best thing to expell all the bile without reabsorption is the liver flush by andreas moritz.
You do 6-10 liver flush, 1-2 kidney cleanse and then you do the homeopathic isotherapy like this (i did it in the morning, 30 min before eating) day 1: 30K, day 3: 200K, day 5: XM, day 7: XMK.

While doing this isotherapy you need to take 7+day fermented kombucha (who potentially contain udp-glucuronic acid & glucaric acid) + 1 supplement of calcium-d-glucarate (1-2gr 3times per day) + food (artichoke) or supplement (chondroitin, artichoke extract) who contain glucuronic acid (facultative) + a lot of fiber (eat only fruit & vegs**), we can add: psyllium, bentonite, charcoal to prevent reabsorption. This isotherapy isn't easy cause it will bring all the symptoms back for 1-3 weeks but it will be fucking magical to get your old body back smile.png

** I've took 20ml of olive oil + 20ml lemon juice after eat some fruits and psyllium+bentonite+charcoal to expell all the bile every morning.

PS: I think it's a good idea to have a good stock of real vitamin A & vitamin D (from sun exposure) before doing the isotherapy, that's what i did, i've eat some carrots & took red ice skate liver oil.
I don't know if it's matter but i've took nux vomica (at the same dosage) 10min after the isotherapic isotretinoin.

Great to hear this worked! Can you explain it more in a step-wise way? Did you do the liver flush for X number of days, then the kidney flush, then 7 days of isotherapy? What can and can't you eat on the isotherapy?

I can't tell if i did it the best way but i did first one kidney flush (3week) and then 10 liver flush. the next day of the 10th flush i started the isotherapy.
I avoided dairy & gluten and took only a little bit of chicken & eggs (only cook with water to not oxyde the cholesterol). best thing is to eat only fruit & vegetables.
For the olive oil + citrus in the morning it's really your choice for the method, cause the isotherapy work for 6weeks so you can do it only 1/2 week or only with low dose everyday or every two day, i took a dose who doesnt cause fatigue for me.
For the calcium-d-glucarate it's better to only take 500mg 2 or 3times i think, when i took more i was a little bit tired.

Hi Annoyy I have also started taking Calcium d glucrate but for some reason the first 2 day i took it i got really terrible migrane headaches.. Now the headaches are gone but still they make feel very sleepy and tired ... It is really annoying that sometimes i feel full of energy .. The sex drives increases so much, the muscle pain goes away and then in couple of hours i feel so sleepy and tired again...

I started off with 500 mg daily and is trying to progress to 750 mg but it is making me feel very tired.. do you have any ideas on how i can increase my intake ? Also, how long you took it?

Quote
MemberMember
157
(@tanedout)

Posted : 10/16/2013 1:13 pm

Annoyy, interested to hear about your solution, so you were advised of this method by a homopath? I like the idea of d glucrate as it removes toxins from the body, but from what I've read you need to use a fairly high dose, and it temporarily reduces steroid hormones too so might not feel like a benefit initially.

Indego, notice you are UK based like me - have you managed to get a DHT test, and what were the results? From what I can see this is liklely to come in low post tane if you're having issues with libido/ED etc. I've just been to the doctors today to request a DHT test and the doctor didn't even know he could request one, but he had the option so one has been requested and I'm going for the blood test on Friday.

Previously had all the usual steroid and sex hormone tests done which came back ok (LH maybe a bit low). Will interested to see what DHT comes back with.

There seems to be a lot of blind hope methods on these forums. People need to push their doctors for tests so they have something to go on. If DHT is low you can raise levels with the herb tribulus (probably at a high-ish dose - working up to 2000mg, and ensure its got a high saponins %, like 95%), and also creatine increases DHT, or go on what a specialist recommends. This is currently my plan - I expect the results to come back showing low DHT, so I will try and raise is either with tribulus/creatine and go back for further tests to see if this has increased DHT and see what effort it's had on other hormones.

I've tried so many herbs and stuff, and some things definitely help a bit like ginseng and gingko, but its not a good enough fix and I want to know what these things are doing, not just take them and hope.

Good luck to everyone, and really push for blood tests and get suggestions from specialists and get the results up here!

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