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Repairing the long-term damage from Accutane

 
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3
(@navile)

Posted : 07/16/2013 5:49 am

Want to test some juice fasting.

Most recommended juice you stumble over right away in every article/book is carrot juice for detoxing the liver. I'm of course aware that we suffer from a toxic vitamin a overdose. Before I knew that accutane is still in my body, I tried once a two weeks fresh pressed carrot juice cure (1 liter a day) meanwhile normal eating. My hands got totally yellow because of all the toxins came out, apart from that my accutane side effects didn't get any worse though. Some of them even got a little bit better during this time.

I saw that juice fasting was recommended in this thread some time ago already to regain health, even if you don't do carrot juice, you eventually get a vitamin a overdose from all the other fruits and especially the vegetables, isn't it?

Since I'm not really an expert on this whole topic yet, I just wanted to ask you for your opinion? Not sure what to do.

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MemberMember
26
(@camaroz28)

Posted : 07/16/2013 6:33 am

I tried once a two weeks fresh pressed carrot juice cure (1 liter a day) meanwhile normal eating. My hands got totally yellow because of all the toxins came out, apart from that my accutane side effects didn't get any worse though. Some of them even got a little bit better during this time.

No Navile, you got the skin yellowing from all the beta-carotene in the carrot juice. If you were really suffering from long-term hypervitaminosis A, you would've felt dreadful (putting it mildly) from all that beta-carotene. Paradoxically, you werent getting the toxins out, but you were willfully ingesting it.

 

http://en.wikipedia.org/wiki/Carotenemia

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MemberMember
26
(@camaroz28)

Posted : 07/16/2013 7:37 am

Navile, sometimes Joseph will induce a case of carotenemia intentionally, to fain jaundice (caused by biliary tract obstruction, of course) for Halloween. He argues that he has to look authentically creepy, if he wants to beat the other kids. The real kicker is this allows Joseph to indulge in trick-or-treating for UDCA. My little chameleon wasn't always so devious.

post-198177-0-53319900-1373978079_thumb.

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MemberMember
157
(@chico-esposito)

Posted : 07/16/2013 8:18 am

 

I tried once a two weeks fresh pressed carrot juice cure (1 liter a day) meanwhile normal eating. My hands got totally yellow because of all the toxins came out, apart from that my accutane side effects didn't get any worse though. Some of them even got a little bit better during this time.

No Navile, you got the skin yellowing from all the beta-carotene in the carrot juice. If you were really suffering from long-term hypervitaminosis A, you would've felt dreadful (putting it mildly) from all that beta-carotene. Paradoxically, you werent getting the toxins out, but you were willfully ingesting it.

http://en.wikipedia.org/wiki/Carotenemia

Camaro is right, you just had carotenemia from the carrot juice.

 

 

Beta carotene doesn't have the same effect in people that have long term accutane side effects. I have a sneaking suspicion that the body has so much retinoic acid available that it doesn't convert beta carotene to retinol anymore, it down regulates the process. Only retinol can push the retinoic acid out of the receptor, because the body doesn't have the option of conversion like it does with carotenoids.

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MemberMember
3
(@navile)

Posted : 07/16/2013 9:42 am

No Navile, you got the skin yellowing from all the beta-carotene in the carrot juice. If you were really suffering from long-term hypervitaminosis A, you would've felt dreadful (putting it mildly) from all that beta-carotene. Paradoxically, you werent getting the toxins out, but you were willfully ingesting it.

http://en.wikipedia....iki/Carotenemia

Camaroz, I know this carotene theorie/fact, but not sure if it's always true? Instead of getting something out, I got more toxic? Just wondering because I have red from several doctors now that it is the toxins coming through the skin because of a liver who can't take it anymore. According to them beetroot and chlorophyll would have to colour skin too. Could it nevertheless be that it had a positive effect on my liver? Looked like it.

Only retinol can push the retinoic acid out of the receptor, because the body doesn't have the option of conversion like it does with carotenoids.

Chico, guess that's the thing you discussed with Joseph? Interested how that will go.

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MemberMember
26
(@camaroz28)

Posted : 07/16/2013 11:33 am

Beta carotene doesn't have the same effect in people that have long term accutane side effects. I have a sneaking suspicion that the body has so much retinoic acid available that it doesn't convert beta carotene to retinol anymore, it down regulates the process. Only retinol can push the retinoic acid out of the receptor, because the body doesn't have the option of conversion like it does with carotenoids.

Boy, there is a real smattering at work here (please provide proof). Look at the table below; there is almost 10,000 IU in half a cup of carrots. There is plenty of beta-carotene and retinol for some fun, yet, Navile professes he actually felt better.

I actually developed problems after years of post Accutane beta-carotene usage. If anything, the conversion is upregulated; your sneaking suspicion doesn't suffice.

Table 2: Selected Food Sources of Vitamin A [8]

Food

mcg RAE per

serving

IU per

serving

Percent

DV*

Sweet potato, baked in skin, 1 whole

1,403

28,058

561

Beef liver, pan fried, 3 ounces

6,582

22,175

444

Spinach, frozen, boiled, cup

573

11,458

229

Carrots, raw, cup

459

9,189

184

Pumpkin pie, commercially prepared, 1 piece

488

3,743

249

Cantaloupe, raw, cup

135

2,706

54

Peppers, sweet, red, raw, cup

117

2,332

47

Mangos, raw, 1 whole

112

2,240

45

Black-eyed peas (cowpeas), boiled, 1 cup

66

1,305

26

Apricots, dried, sulfured, 10 halves

63

1,261

25

Broccoli, boiled, cup

60

1,208

24

Ice cream, French vanilla, soft serve, 1 cup

278

1,014

20

Cheese, ricotta, part skim, 1 cup

263

945

19

Tomato juice, canned, cup

42

821

16

Herring, Atlantic, pickled, 3 ounces

219

731

15

Ready-to-eat cereal, fortified with 10% of the DV for vitamin A, 1 cup (more heavily fortified cereals might provide more of the DV)

127149

500

10

Milk, fat-free or skim, with added vitamin A and vitamin D, 1 cup

149

500

10

Baked beans, canned, plain or vegetarian, 1 cup

13

274

5

Egg, hard boiled, 1 large

75

260

5

Summer squash, all varieties, boiled, cup

10

191

4

Salmon, sockeye, cooked, 3 ounces

59

176

4

Yogurt, plain, low fat, 1 cup

32

116

2

Pistachio nuts, dry roasted, 1 ounce

4

73

1

Tuna, light, canned in oil, drained solids, 3 ounces

20

65

1

Chicken, breast meat and skin, roasted, breast

5

18

0

*DV = Daily Value. DVs were developed by the U.S. Food and Drug Administration (FDA) to help consumers compare the nutrient contents of products within the context of a total diet. The DV for vitamin A is 5,000 IU for adults and children age 4 and older. Foods providing 20% or more of the DV are considered to be high sources of a nutrient. The U.S. Department of Agriculture's (USDA's) Nutrient Database Web site [8] lists the nutrient content of many foods and provides a comprehensive list of foods containing vitamin A in IUs and foods containing beta-carotene in mcg.

 

Camaroz, I know this carotene theorie/fact, but not sure if it's always true? Instead of getting something out, I got more toxic? Just wondering because I have red from several doctors now that it is the toxins coming through the skin because of a liver who can't take it anymore. According to them beetroot and chlorophyll would have to colour skin too. Could it nevertheless be that it had a positive effect on my liver? Looked like it.

It is not a theory, it is a fact that you decided to ignore in favor of extreme conjecture. It didn't harm because you are not suffering from simple hypervitaminosis A. There was plenty of retinol alone which would have induced an effect, plus all the BC.

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MemberMember
3
(@navile)

Posted : 07/16/2013 11:43 am

I'm still on my strict alkaline nutrition by the way. Means only fruits, vegetables, juices, smoothies, nuts, oils. If you look at this list, I get the complete overdose everyday since quite a while. I'm just continuing this nutrition because my once bad blood flow which was caused by the poisoned liver, is better than ever, almost normal, hairloss gone, etc..

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MemberMember
91
(@josephbuchignani)

Posted : 07/16/2013 7:31 pm

There's a reason Camaroz and I get along like oil and water. His digit ratio is extremely feminine - 1.0. Mine is extremely masculine - .91
The result is his lashing out at anyone on the thread who displays strong masculine polarity. He is - in a very literal, medical, and scientific sense - only half a man. Hence the cats, red pumps, snark and feminism.
I know that he feels he is scoring points with the passive aggressive girlish backbiting. But to my ears, he is just endlessly advertising his mother's neolithic-disease-agent-riddled womb's failure to adequately testosteronize her gestating son.
I do wonder whether his persistent attentions are symptomatic of some kind of unresolved homosexual tendency. As I am currently engaged, I think it best to stop responding to what may very well be conflicted flirtation.
In sum, nothing can mitigate our instinctive antipathy. The best course of action would be to ignore each other's personalities and focus solely on content. I will unilaterally do so henceforth.
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MemberMember
26
(@camaroz28)

Posted : 07/16/2013 8:41 pm

I get the complete overdose everyday since quite a while. I'm just continuing this nutrition because my once bad blood flow which was caused by the poisoned liver, is better than ever, almost normal, hairloss gone, etc..

I appreciate you making my point even clearer. There is definitely no hypervitaminosis A at work.

 

 

The result is his lashing out at anyone on the thread who displays strong masculine polarity. He is - in a very literal, medical, and scientific sense - only half a man. Hence the cats, red pumps, snark and feminism.

I thought you looked cute in the little skeleton suit. So, does my characterization of you as cute make me overly feminine too? I am man enough to take it. No, it's not just cats and feminism; you forgot the Mustang and the construction business.

 

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MemberMember
26
(@camaroz28)

Posted : 07/16/2013 9:11 pm

 

I do wonder whether his persistent attentions are symptomatic of some kind of unresolved homosexual tendency. As I am currently engaged, I think it best to stop responding to what may very well be conflicted flirtation.

What petty little man comes here and says that, in this day and age? You have really laid bare your exsanguinated heart, and accompanying spirit. I have had gay men hit on me (I'm honored); and, I have had women that I have just slept with call me possibly gay (I'm honored). Women don't like it when you bring them to climax too quickly, and they can't reciprocate, so they lash out. I guess, no one likes a clearly-defined large deficit, but that is just life. I promise to never comment on your future succession of endless 'recoveries.' How dare you impugn homosexuality, on this site that gives you a voice.

 

 

I know that he feels he is scoring points with the passive aggressive girlish backbiting. But to my ears, he is just endlessly advertising his mother's neolithic-disease-agent-riddled womb's failure to adequately testosteronize her gestating son.

You really do have a raven and vampire bat living in your heart. Steph, I'd like a serving of sexism charges laid against this man(?). I am funny, but you are just dark, and, obviously wounded.

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MemberMember
22
(@sasquire)

Posted : 07/16/2013 11:22 pm

At least accutane keeps us calm :)

So calm.

Stabs random chicken.

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MemberMember
3
(@navile)

Posted : 07/17/2013 11:14 am

I appreciate you making my point even clearer. There is definitely no hypervitaminosis A at work.

could I try blue ice cod liver then, or is there any difference?

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MemberMember
2
(@darran)

Posted : 07/17/2013 4:07 pm

Guys stop being fuckwitts and focus on the goal of the thread, if you want to bicker...please just privet message each other...no one cares and honestly you're really just deterring people from the forum.

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MemberMember
157
(@chico-esposito)

Posted : 07/17/2013 4:50 pm

Guys stop being fuckwitts and focus on the goal of the thread, if you want to bicker...please just privet message each other...no one cares and honestly you're really just deterring people from the forum.

Totally agree and thats not aimed at Joseph because some of his content can be quite informative, it's more so Camaro seeing that he's diluted this thread with countless petty squabbles. It's affected the content and he needs to pack it in.

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MemberMember
26
(@camaroz28)

Posted : 07/17/2013 7:53 pm

Guys stop being fuckwitts and focus on the goal of the thread, if you want to bicker...please just privet message each other...no one cares and honestly you're really just deterring people from the forum.

Hi, formerly (still) irrelevant man; please proceed somewhere else. I am sure your family is really proud.

Totally agree and thats not aimed at Joseph because some of his content can be quite informative, it's more so Camaro seeing that he's diluted this thread with countless petty squabbles. It's affected the content and he needs to pack it in.

Your moronic simplifications needed to be pointed out; I'm sorry you feel so strongly. You have said the dumbest things I have seen on this thread (DHT inhibition irrelevant; retinol ingestion causes massive retinoic acid release). What have you achieved in the past year on this forum?

 

 

I appreciate you making my point even clearer. There is definitely no hypervitaminosis A at work.

could I try blue ice cod liver then, or is there any difference?

You sure can sir; tell, Chico to keep avoiding the egg isle at his local grocery store. I am sure that it takes all he has to accomplish. I almost forgot; he needs to avoid the biscuit isle too.

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MemberMember
91
(@josephbuchignani)

Posted : 07/17/2013 11:30 pm

There is a major difference between blue ice fermented cod liver oil vs blue ice fermented cod liver oil with grass fed butter oil. Dr. Western Price and subsequent testing by the Western Price Foundation found that the cod is much more effective when combined with butter oil. You are only getting the K2 from the butter oil. See here: http://www.westonaprice.org/cod-liver-oil/cod-liver-oil-basics
If you don't want to hear someone, I recommend using the ignore function, which is in your profile area.
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MemberMember
3
(@navile)

Posted : 07/18/2013 1:29 am

 

There is a major difference between blue ice fermented cod liver oil vs blue ice fermented cod liver oil with grass fed butter oil. Dr. Western Price and subsequent testing by the Western Price Foundation found that the cod is much more effective when combined with butter oil. You are only getting the K2 from the butter oil. See here: http://www.westonaprice.org/cod-liver-oil/cod-liver-oil-basics
If you don't want to hear someone, I recommend using the ignore function, which is in your profile area.

I see, I actually also meant the one with butter oil. (green pasture)

"fat-soluble vitamin A naturally found in foods like cod liver oil, liver, and butterfat is safe at up to ten times the doses of water-soluble"

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MemberMember
26
(@camaroz28)

Posted : 07/18/2013 2:47 am

 

I see, I actually also meant the one with butter oil. (green pasture)

"fat-soluble vitamin A naturally found in foods like cod liver oil, liver, and butterfat is safe at up to ten times the doses of water-soluble"

Joey was in a state when he attempted to unravel your attempted meaning. I will PM you later this evening.

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MemberMember
0
(@udca)

Posted : 07/18/2013 6:18 am

You know the afterlife isn't that bad. Navile, just take it at the recommended dosage; ignore the comparisons to water-soluble vitamin A.

Researchers have succeeded in creating water-soluble forms of vitamin A, which they believed could reduce the potential for toxicity.[58] However, a 2003 study found water-soluble vitamin A was approximately 10 times as toxic as fat-soluble vitamin.[

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MemberMember
157
(@chico-esposito)

Posted : 07/18/2013 7:37 am

I'm not going to lower myself to your level camaroz with these ad hominem attacks, but you did raise one point worth retort and that was the fact i devalue the role of dht inhibitors in post accutane problems. I never said that, or if i did i certainly didn't mean too in that context. Dht inhibitors can be problematic for those with post accutane HAIR LOSS, but for other side effects it really isn't a relevant factor.

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MemberMember
85
(@and1)

Posted : 07/19/2013 2:27 am

Found this nice article on the liver. In the BB community you can often find hands on advice for everybody - the layman - to understand which has passed the test of time on both sides of the atlantic. Really like this article.

http://www.t-nation.com/free_online_article/most_recent/liver_let_die

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MemberMember
85
(@and1)

Posted : 07/19/2013 3:16 am

Just came across the following supplement which is mentioned on some BB message boards as being superior to Liv.52. Liv.52 is the supplement which in combination with the other supps I am currently taking has allowed me to avoid withdrawl symptoms after getting off UDCA.

http://www.synthetek.com/products/synthergine-liver-protectant/

ingredients:

Arginine HCL Arginine is required for proper elimination of urea from the body. This occurs through a critical metabolic cycle which detoxifies the body of nitrogen compounds that are manufactured in the liver or by intestinal bacteria action. Subtle impairments of the livers function can often lead to subclinical symptoms of hyperammonemia, which is the condition of poor excretion of urea. Symptoms of hyperammonemia may include chronic fatigue, headache, irritability, occasional diarrhea or nausea, lack of concentration, mental confusion, and intolerance to various foods, particularly high-protein foods.

Sodium Glucuronate is a nutritional substance used by the liver to bind to toxins (excess hormones, food additives, cigarette smoke, etc.) and eliminate them from the system. Of all the chemical reactions taking place in the liver cell, the elimination of toxic substances via glucuronate binding is considered the most important. Clinical studies have shown glucuronate supplementation can improve liver function considerably because it reduces stress on the liver and enhances the organas ability to detoxify.

Di-isopropylamine Dichloroacetate (DADA) is a peripheral and cerebral arteriole vasodilator. DADA assists in hepatic detoxification of heavy metals, nitrites, and organophosphates. DADA provides muscular and hepatic system support in athletic animals, especially during the stress of training and hard physical work, and in the presence of high energy diets. DADA is a potent peripheral and cerebral arteriole vasodilator, and assists in the hepatic detoxification of a number of metallic and chemical metabolites including intoxication by heavy metals, nitrites and organophosphates.

Lysine HCL one of the 8 essential amino acids. It improves immune system function and it helps tissues regenerate themselves after damage (such as liver tissue after toxin damage)

Methionine HCL an essential, sulfur-containing amino acid. It is the source of sulfur for numerous compounds in the body, including the amino acids cysteine and taurine. The body uses sulfur to influence hair follicles and promote healthy hair, skin, and nail growth. Sulfur also increases the livers production of lecithin (which reduces cholesterol), reduces liver fat, protects the kidneys, helps the body to excrete heavy metals, and reduces bladder irritation by regulating the formation of ammonia in the urine. Methionine is a lipotropic a nutrient that helps prevent fat accumulation in the liver, and usually helps detoxify metabolic wastes and toxins.

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MemberMember
0
(@udca)

Posted : 07/19/2013 4:16 am

I am so glad we were warned about UDCA; I guess, I should change my name. I am trying to taper down slowly.

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MemberMember
85
(@and1)

Posted : 07/19/2013 4:42 am

I am so glad we were warned about UDCA; I guess, I should change my name. I am trying to taper down slowly.

To be honest, I am still not 100% convinced that the concept of UDCA is bad.

Maybe pharma has just to go back to the lab to engineer a synthetic bile that is safer, because the idea of supplementing bile, that is, bear bile is actually coming from TMC. Bear bile has historically been used as an ingredient in traditional Chinese medicine. The traditional way to acquire bear bile was to kill a wild animal and remove its gall bladder. My mom was cured of having to use certain pharmaceuticals for the rest of her life after a 18 months treatment with TMC, so I think highly of it. UDCA was working for me, left me with some lasting health gains and it showed me where I can take my health as I did experience some withdrawl after getting off it the first time.

http://en.wikipedia.org/wiki/Bile_bear

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MemberMember
91
(@josephbuchignani)

Posted : 07/19/2013 7:11 am

As far as I can tell, the cases where UDCA is dangerous are cases where any bile is dangerous - which is a problem since the body produces bile with or without supplementation.

Interesting liver supp, thanks.

No significant changes to report. My stomach/bowels are still A+. Trying to eliminate the polyphasic 1am-6am zombie mode. Might dose Blue Ice twice a day to see if that helps. When I finish ironing that out I'll test the rest of the iherb order. Overeating issue from fatigue is gone after adjusting to acacia fiber. DO ramp it up carefully, like the package says. Actually experienced constipation for the first time... ever? Clearly taking probiotics without fiber prebiotics was plain idiocy. What can I say, insoluble veggie fiber's painful results scared me off.

Now if I can just be Limitless round the clock, I'll be satisfied...

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