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Repairing the long-term damage from Accutane

 
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157
(@chico-esposito)

Posted : 06/17/2013 11:49 am

 

I don't doubt that hypervitaminosis A caused your condition, Chico. And the nature of it is interesting support for your Vit A recycling hypothesis - rapid skin shedding seems more like ongoing hypervitaminosis A, than a one-off incident.
I assume the skin shedding accelerates whenever you eat foods containing retinoids?
But again, my question was whether you actually tested that shrimp affects you, or you merely theorize that it would.
" ALSO, I AM SURE THE RESEARCHERS ARE FEVERISHLY TRYING TO WORK OUT HOW TO CLEAR THE RETINOIDS FROM YOUR RECEPTORS."
Sarcasm?
"If storage issues are at work, they play a small role, not the principle role as you always elude to. The problem is the drug inhibiting it's own metabolism., amongst other things."
Sounds right.

It doesn't accelerate the shedding per se, but it gives me all the same symptoms of being back on accutane, my mouth cracks up and needs vaseline, my skin scabs up, eyes get bloodshot and things like this. Does shrimp affect me? it does, but to a lesser extent than other foods, i've eaten it many times, what happens is i can actually feel it pretty much from the moment it's eaten, it's not like a placebo, i can eat out and get something from a restaurant for instance, after about 30 seconds of eating it i can sense that there is retinol in it, just by the way my body reacts. My vision goes a little bit funny and my eyes get sore, i can feel my face heating up, if i put my hand on my cheeks it's warm to the touch, inside my head there is an almost tingly sensation, not like pins and needles but it's a definite physical feeling. The intensity of these symptoms is related to the amount of retinol in the food. Cod liver oil is the worst, butter is really bad too, shrimp would be a lot milder.

It sounds crazy, i feel crazy saying it, but maybe others might relate to the physical reaction they get when they eat retinol containing foods, i don't know maybe it's just me.

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91
(@josephbuchignani)

Posted : 06/17/2013 12:06 pm

And you're still a liar with poor reading comprehension.
"".....in which case use UDCA unless/until it progresses to the point where UDCA starts doing more harm than good. Then get a transplant." And you are still trying to weasel your way out."
Only works if you assume then follows immediately - a faulty assumption.
Very interesting Chico. Sounds like you've repeatedly tested this, and gotten a strong reading at variable strength correlated to retinol content.
I may or may not have noticed something similar, purely as a digestive reaction. Hard to say since I'm sensitive to almost everything, including all fat.
One more methodological objection. What is your baseline? How is it even possible to avoid retinol containing foods? What do you eat? How do you feel at your basline? If you can't get a baseline, you can't reliably isolate a deviation.
Sounds like once again Accutane can screw up unrelated systems most anywhere, in weird chronic ways. They rhyme, but that's all.
Ah Camaroz, I sympathize with your plight. I am after all the descendant of two generations of lawyers. Recently I was even the subject of a certain sci fi / fantasy author's latest book - as the villain. Just do as my memento mori, and grin and bear it.
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85
(@and1)

Posted : 06/17/2013 12:32 pm

You guys know that you are wasting resources in this discussion that is getting us nowhere, namely time and effort.

I'd like to see us - once more people have tried UDCA - to find ways to leverage the "healing" effects of UDCA by combining it with other supplements and protocols to reach the goal of not needing UDCA long-term. As I have writte before I am currently combining UDCA with P&B shakes (psyllium husk and bentonite clay) and drinking a mix of lemon juice and olive oil. I used to take P&B shakes twice daily, now after taking UDCA again, I only take one big shake in the ealry morning.Still too early to draw final conclusions, but my skin is looking better compared to when I was only supplementing with UDCA.

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85
(@and1)

Posted : 06/17/2013 1:38 pm

Paradoxically this study talks about the potential benefits of combining UDCA and retinoic acid:

http://onlinelibrary.wiley.com/doi/10.1002/hep.24047/pdf

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MemberMember
157
(@chico-esposito)

Posted : 06/17/2013 5:15 pm

It's a real shame Liver longer isn't on the market anymore, that was legit TUDCA and that stuff worked, nowadays i doubt whether most of the stuff they sell on the internet is even real. I've got some Brawn TUDCA recently and i bit into a tablet and there is no acidic taste to it whatsoever, it's probably just paracetamol tablets that they put in a nice container at a 1000% mark up, this is the unregulated supplement industry for you, it's the wild west out here. To Joseph and Believe, does your UDCA taste acidic if you bite into the tablet?

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26
(@camaroz28)

Posted : 06/17/2013 9:08 pm

"When you were beating me, I had a BIG problem humbly acknowledging it." Yes right, you keeping telling us that you are so smart, and that you are back at work kicking goals. YOU HAVE NEVER TOLD US WHAT YOU DO GIVEN THAT YOU ARE SO SMART which is odd given your ego. I know why because you are half wit. Know apply some aloe to your ego and move along.

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26
(@camaroz28)

Posted : 06/17/2013 10:00 pm

I'd pile you all in a clown car with Joseph as the driver now that would be entertaining haha

 

Also people- can we stop requoting people's long winded quotes in response just tag themthem, they will see it were here all the freaking time reading every post it's not like your gonna miss it were addressing using user names it's so irritating........

Yes Joseph, as the leader of the clown troupe, please take everyone to the circus to watch your perform. You deserve a bigger stage than this thread.

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MemberMember
91
(@josephbuchignani)

Posted : 06/18/2013 12:43 am

Believe, my pills are so bitter I hate to take them except with food to immediately wash away the taste. There is no coating; it is just 100% easily powdering UDCA.
It wasn't a waste, I learned quite a bit about the liver and liver injuries. The Accutane epithelial connection in the tiny upstream networks is fascinating.
ACV, tea tree oil and benzoyl peroxide have my skin looking better than ever, plus I started showering with herbal lavendar and sandalwood concoctions, very nice.
What a fascinating article about retinoic acid and UDCA working better in combination. So Accutane is certainly ACTIVE in the liver. But of course we already knew that. Nonetheless, I wouldn't try combining them post-injury.
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85
(@and1)

Posted : 06/18/2013 2:30 am

My tablets have a coating and I don't bite on them, so no acidic taste to report. I try to get them down as quickly as possible. However, they are the real stuff, I need a prescription and then go to a pharmacy to get them.

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MemberMember
91
(@josephbuchignani)

Posted : 06/18/2013 3:02 am

"YOU HAVE NEVER TOLD US WHAT YOU DO GIVEN THAT YOU ARE SO SMART which is odd given your ego. I know why because you are half wit."

That's amusing. I'm a trainer for a test that's accepted as an IQ test proxy by a high IQ organization more exclusive than Mensa.

You sure do know how to ask the wrong questions...

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26
(@camaroz28)

Posted : 06/18/2013 4:23 am

"YOU HAVE NEVER TOLD US WHAT YOU DO GIVEN THAT YOU ARE SO SMART which is odd given your ego. I know why because you are half wit."

That's amusing. I'm a trainer for a test that's accepted as an IQ test proxy by a high IQ organization more exclusive than Mensa.

You sure do know how to ask the wrong questions...

And, you were frightened to say this before because? Why the delay and why not make mention of this before, when you last posted? As usual I had caught you out, and it took more time to come up with a sufficient lie. Im still not impressed. What is the name of this exclusive institution (you seem like a name-dropper)? I am not going to call, if you're wondering.

Descended from lawyers ha? I guess you were the letdown out of the bunch. Im guessing there is also a very-productive construction company in there too (you copied everything else I said)? You are so transparent. You are more like a wheel of cheese descending down a hill temporarily acquiring air-time as you skip over a turd. Real wit is clearly evident; you dont have to cut and paste it if you have it. Peace.

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MemberMember
91
(@josephbuchignani)

Posted : 06/18/2013 11:12 am

For those with Accutane digestive difficulties, here's my iHerb purchase stack.

It's very conservative. Most I've previously tested, and know are safe. I'll be testing them this round for effect size. I want to know whether I can make additional gains by focusing on digestion, past the current UDCA + elimination diet + extra water regimen.

There are also a few things in there for skin and allergies and liver, but it's mostly digestive.

cart 1
[Edited link out]
cart 2
[Edited link out]
coupon code:
ZJD339
"Why the delay and why not make mention of this before, when you last posted?"
Because I have you on block, and only read your posts when I'm bored or expect you to say something useful. I didn't expect, so it waited until bored.
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MemberMember
85
(@and1)

Posted : 06/18/2013 3:19 pm

Nice shopping carts.

Black soap really works great for me. From what I read it is a good brand you got, don't know if you are trying this stuff for the first time.

I was considering to buy the same brand/item when I first wanted to try black soap, but chose "dudu osun black soap" and stuck with it. If I remember correctly I chose dudu mainly because you can buy it often times really cheap in bulk on ebay, Whereas iherb orders always go through the customs which is a downer for me. I have gotten 150 g of dudun osun black soap as cheap as 1,50 a piece and shipping was free from the UK as I bought a 16 pack. You can probably get it even cheaper because it is from what I remember an african brand that made its way into Europe and the US through african communities living there. It is like a staple product and not some premium brand with fancy marketing to make it appeal to the health conscious crowd.

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78
(@movingon)

Posted : 06/18/2013 5:40 pm

Why do people shit on other people when they find stuff that works for them??!! It's not possible for anyone here to know all of the long-term effects/short-term effects. everyone is different. People kept telling me that iodine wasn't going to fix me....but it sure has shit has ridden me of joint paint for 2 weeks now. Clearly something is going on with thyroid or elsewhere in my body. I was fine up until about 1 year ago. Perhaps the accutane finally depleted my body's ability to process it's own iodine/blocked it's use. Just a thought. If it works for you, and you've done your research,....try it.

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Gladiatoro, camaroz28, Gladiatoro and 3 people reacted
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148
(@oli-girl)

Posted : 06/18/2013 7:38 pm

You guys make me dizzy trying to catch up and read all the posts in the last couple days while on vacation lol! :)

 

Can't we all get along! We all suffer and it can't help going back and forth like this.

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MovingOn, Gladiatoro, MovingOn and 3 people reacted
MemberMember
91
(@josephbuchignani)

Posted : 06/18/2013 8:18 pm

I'm not at all opposed to iodine. It has a big effect for me too, but is too harsh in supplement form, so I get it in food form instead.

Thanks for the heads up on dudusun. This is my first time trying black soap, so if I like it I might investigate bulk buy.

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MemberMember
26
(@camaroz28)

Posted : 06/18/2013 10:33 pm

Why do people shit on other people when they find stuff that works for them??!! It's not possible for anyone here to know all of the long-term effects/short-term effects. everyone is different. People kept telling me that iodine wasn't going to fix me

Part of this post was sent in PM form. I have decided to post this publically with minor revisions.

I am not doing #2s on people; people poop in their own pants because they are complacent, and then blame the system.

People go insane here when they are told not to take a handful of DHT inhibitors. That is stupid. He was trying to encourage people to take UDCA long term without doctor supervision, because he wants to be seen as the Messiah of this thread. He said that doctors are aware of the contraindication in seemingly applicable cases, but don't care because they want to improve life quality, no matter what. This is not true; doctors were genuinely surprised, and did not intend to harm people. He maintained his rubbish stance, because he was trying to show that you should use it no matter what as the doctors clearly are. He actually said, that one should use it and gain any benefits from it, until such time that one would require transplant surgery. All this was done to preserve his "completely safe" theory. The aforementioned behavior is twisted.

It took him years to decide he has cholestasis, which he doesn't have. He only discovered it, because he was trolling the meathead forums, and decided to become an expert on the condition. I have always done the right thing, despite being a bit smug sometimes to other smug people.

Someone here actually recommended kratom which is a known antiandrogen, and someone else on this forum has actually tried it. I stumbled upon his posts on another forum clearly stating that kratom was messing him up. Other people on the forum told him that it indeed would mess him up, because it is an antiandrogen. He said that when on kratom he could not ejaculate even after an hour of awesome sex. This person despite his knowledge has not stepped in to warn people here (he is always around). See my point; no one here as anyone else back despite protestations to the contrary.

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MemberMember
26
(@camaroz28)

Posted : 06/19/2013 2:26 am

 

Joseph, the problem I have with your regimen is it is so much a coping mechanism. Accutane did deep structural damage. I simply don't see how you will ever be able to constantly manage forever. You will constantly crash. As you constantly report here you're 'cured' and then your very next post is your latest problems.

 

 

It's not all useless, but it's not suitably corrective either. Including the f-ing scallops!

Well said Lukez.

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157
(@chico-esposito)

Posted : 06/19/2013 6:34 am

I can understand the reasoning for him recommending it, although the effects on each individual are different. I think it stemmed from the article that stated hypervitaminosis A can cause cholastasis. Ultimately it's a prescription drug and unless you have your doctors permission your on shaky ground to start with. I personally was going to recommend it, then edited my post because i don't like recommending pharma products, i think natural is the way, but when the damage is severe enough, a little bit of herbs isn't really going to cut it.

In my humble opinion if Joseph is taking 2 grams of this stuff per day, he should be radically upping his monounsaturated fat intake and maybe trying to add certain foods he can not tolerate back into the diet to see whether the udca has done for him what he's suggesting it does. Taking a bile restoring agent and then refusing to eat fat is kind of pointless, the whole point is too increase fat and see how the body handles it with the UDCA.

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91
(@josephbuchignani)

Posted : 06/19/2013 7:32 am

" He said that doctors are aware of the contraindication in seemingly applicable cases, but don't care because they want to improve life quality, no matter what."
Lying again. Provide the quote.
"because he was trying to show that you should use it no matter what as the doctors clearly are. "
Lie.
"He actually said, that one should use it and gain any benefits from it, until such time that one would require transplant surgery"
Lie.
Lukez's point applies to when I was cycling between lvl 0 and 1, jobless, desperate. Of course I will not be overly objective in such a situation; it would be too demotivating.
I'm now stable at lvl 4, making rapid progress to lvl 5. And of course, keen to investigate whether my liver condition is stable or progressive, in the latter case of which UDCA may at some point become counterproductive.
"In my humble opinion if Joseph is taking 2 grams of this stuff per day, he should be radically upping his monounsaturated fat intake and maybe trying to add certain foods he can not tolerate back into the diet to see whether the udca has done for him what he's suggesting it does. Taking a bile restoring agent and then refusing to eat fat is kind of pointless, the whole point is too increase fat and see how the body handles it with the UDCA."
I don't agree that is the whole point. Being functional is the whole point at lvl 4, and UDCA helps that in multiple ways, whether or not one is eating fat.
However, I am running those tests. I've successfully switched to whole fat milk for weeks now, and over the last few days I've tried eating a whole chicken. I still preferentially eat the lean meat, but I'm getting a lot more fat and connective tissue than when I was eating lean frozen pieces. There appear to be no ill effects so far.
I won't look to expand much further than that until I'm done testing the new round of supplements. Isolating effects requires a disciplined intervention schedule. I'm not interested in wasting time generating sloppy data.
What Camaroz fails to realize is I am recommending a UDCA trial to people such as myself whose liver tests have ALREADY COME BACK NEGATIVE. The known dangers of UDCA are for people with diagnosed severe liver conditions. The Venn diagrams for those two groups do not intersect.
I am not sure why his reading comprehension and reasoning are so broken on this issue; perhaps his antagonistic ego blinds him. On androgen issues he's pretty sound for all I can tell.
Anyhow, back to test prep, thanks for the break.
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26
(@camaroz28)

Posted : 06/19/2013 8:30 am

You didn't understand the articles because they went against your untenable "completely safe" stance, which you had to uphold no matter what. You couldn't understand me, because I was kicking your butt on multiple points and you were in a panic. You admitted to having thoroughly misunderstood, and you tried to reconcile with a sloppy ad hoc case of cut and paste. You were caught out on that point and you're STILL really embarrassed.

 

 

My win over you was so unanimous that Steph likened it to me doing a #2 on you. I felt it was a clear victory, but I did not like the characterization, hence the recapitulation for her purposes.

 

I have nothing to say to you. Just keep rolling down the hill.

 

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MemberMember
26
(@camaroz28)

Posted : 06/19/2013 8:50 am

 

The stupid thing is that lots of people see adverse effects reports FROM BLOCKED BILE DUCTS and therefore take massively subtherapeutic doses, leaving money/health/lifespan on the table. RTFP.
The ridiculous thing is that UDCA is so good for you there is even a DEBATE about whether people with BLOCKED BILE DUCTS should STILL take it.

Dummy, right here are your mistakes, and don't call me a liar. This clearly proved your ignorance and stupidity.

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91
(@josephbuchignani)

Posted : 06/19/2013 9:49 am

It's a perfectly legit statement. They've tried it on infants with atresia, for heaven's sake. You already made this point, I answered it, and you dropped my answer. In debate, this is an automatic loss.

Anyhow, I recognize the behavior pattern now. Probably +2SD intelligence, used to being the big fish in the pond, can make useful contributions on subject matter. Often initial altruistic motivation, but does not engage beyond surface level, once disagreement occurs, continues conflict for ego objective. Depth does not increase with conflict duration; misunderstandings of opponent's position are not corrected, since this would compromise ego objective, and more misinterpretations are deliberately and maliciously introduced. Righteous sense of self-justification; extreme rudeness; accustomed to winning by beating up lesser minds. Will keep going indefinitely, but new content absorption and production drops to zero.

It's been an interesting show, thanks.

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MemberMember
26
(@camaroz28)

Posted : 06/19/2013 11:09 am

Anyhow, I recognize the behavior pattern now. Probably +2SD intelligence, used to being the big fish in the pond, can make useful contributions on subject matter. Often initial altruistic motivation, but does not engage beyond surface level, once disagreement occurs, continues conflict for ego objective. Depth does not increase with conflict duration; misunderstandings of opponent's position are not corrected, since this would compromise ego objective, and more misinterpretations are deliberately and maliciously introduced. Righteous sense of self-justification; extreme rudeness; accustomed to winning by beating up lesser minds. Will keep going indefinitely, but new content absorption and production drops to zero.

It's been an interesting show, thanks.

I am staggered; as it again became clear that our tapioca pudding was losing, he again resorted to cutting and pasting to get to higher ground. This time he cut and paste his psychiatrist's assessment of himself and attempted to transfer. Yet again, it clearly is not original work. My synopsis and creativity wins.

Gladiola, I noticed you ensconced behind the thick shrubbery hiding like a scorned spinster waiting to throw rocks (because of the kratom remark), because you have never been loved. I implore you to come out from behind the thick foliage as many other women have and be free.

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MemberMember
23
(@perseverance92)

Posted : 06/19/2013 1:15 pm

I was well aware of the cons of taking Accutane. But i never knew that it could cause erectile dysfunction and low libido.Well,in that case i accept acne and not accutane! [Edited image out] I love my masculinity more than my aesthetics. (Your girl would pardon you for acne but not if you don't perform well,you know [Edited image out]

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acne1776, Chico Esposito, oli girl and 6 people reacted