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Trifarotene (Aklief®)

Topical Retinoid
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Trifarotene works through the following mechanisms:

Anti-keratinization activity

Trifarotene reduces the production of keratin (a sticky skin protein), which helps skin cells shed from the skin. This helps clear and prevent clogged pores.

Anti-inflammatory activity

Trifarotene reduces inflammation in the skin.

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© 1996-2025 The American Acne Association. All rights reserved. Our website services, content, and products are for informational purposes only. The American Acne Association does not provide medical advice, diagnosis, or treatment. See additional information.
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