Antiandrogen
Reviews
4.1
1330 Reviews
Antiandrogen
Efficacy
68%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Antiandrogen
Side Effects
High
Antiandrogen
Acne.org’s Real World Take
“Spiro” has been shown to work in a real and noticeable way most of the time. However, messing with hormones is messing with hormones and it’s best to proceed with caution.
Antiandrogen
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Spironolactone
Compare To Other Treatments
5
51%
4
28%
3
10.1%
2
4.9%
1
6.1%

Used Spironolactone? Rate It:

Choose from 1 to 5 stars
July 24, 2009

Pros:

Feel Fantastic!!!!!

Cons:

None so far

I have only used this for a week, but by the third day I felt the best I have since I was about 16, and I'm now 36. I just feel so Light and active. My greasy Dairy sensitive dermatitis scalp has cleared up completely - I can eat cheese again!!!! YAY!!!! My itchy skin has gone, my oedema and morning fluid-filled head has cleared completely. My sinuses are clear for the first time since I was about 12. For me this is a silver bullet so far, no side effects yet, I will kiss my endocrinologist next time I see him. ( he might not like that! ), haha. Hopefully the good effects will continue. Have lost half a kilo, Probably just fluid. Not going to the loo much more than usual, either. Loving it, haven't used long enough to judge about skin or anything else, but I just feel so good that I don't care if it doesn't clear my acne!
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April 19, 2009

Pros:

cleared up my hormonal acne when nothing else would work

Cons:

can't be used during pregnancy or breast feeding; decreased libido; decreased energy

After going to several dermatologists over the years and trying many different medications that didn't help with my painful acne, I tried a new dermatologist and they recommended spironolactone. It took about 3 months to start seeing consistent results but it has completely cleared up my acne and has been working great for over a year now. Unfortunately the medication cannot be taken during pregnancy or breast feeding. Also, I have noticed decreased libido and energy, which I didn't attribute to the medication until recently when my obgyn mentioned that the hormonal effects of the medication could cause these side effects. Has anyone else noticed these side effects?
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April 16, 2009

Pros:

seems to make the pimples/cysts i get come to a head faster, less oily hair in between washes. mild weight loss (from the diuretic effect of the pills)

Cons:

Excessive thirst ans more frequent periods

I have only been on this medication 3 wks and have not really noticed a difference in my skin, altho I know it takes 2-3 months for improvements to show. I am a 25 year old who suffers with a moderate case of polycystic ovaries (all my andregen levels such as DHEA and testosterone are elevated) I have suffered with acne since I was 13 years old, it is mainly along my jaw line and overall my complexion which permanently looks clogged and I have open pores, I have previously been on the BC pills Dianette, Yasmin & various antibiotics over the years which really did nothing for my acne and the BC pills made me depressed & caused weight gain. since starting Spiro my skin has become slightly worse but this seems common when starting new treatments so i hope its only temporary. I did get 2 periods 2 wks apart since starting it also which never happens to me, (as my cycles are longer than normal due to PCOS) & i did find it a con.Im just waiting in hope now and will report back in a month!!!
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April 6, 2009

Pros:

Less oil, got rid of hormonal acne around the mouth.

Cons:

Fatigue

Absolutey a savior for hormonal acne!!
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April 5, 2009

Pros:

This is the only thing which works consistently. I take 200mg daily and have forgotten about spots!!

Cons:

Thirsty - I have to drink more fluids as this is a diuretic

:)
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March 31, 2009

Pros:

Much clearer skin, less oily- couldn't believe how good my skin was

Cons:

Stomach craps, mood swings, tired, frequently need to empty bladder- the night is the worse, no periods.

I am now 33 and suffered with acne since I was 10 years old. I have tried everything possibly available from the over the counter, herbal remedies, prescribed medication to expensive products but nothing worked. I have taken Spirolactone for a year which was absolutely fantastic- clearer skin like I never seen it before. I have stopped 2 months ago with the recommendation of my GP due to the possible side effects this could have on long term use. My skin has now become much oiler and the dreaded outbreaks of horrible spots on my face/ chest and back as before. I am considering going back onto Spirolactone despite the risk associated such as ovarian cancer.
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March 4, 2009

Pros:

Clear skin, no more oily skin

Cons:

Slight dryness

After being told by my doctor that there is no cure for oily skin, I researched spironolactone online and got another doctor to prescribe it. My skin was so oily I had to blot it a half hour after washing. It really made me feel uncomfortable and unclean. I would wake up to a wet face and new breakouts every morning. It took a while but during my third month on the medication the oil completely stopped. Now I do not blot my face at all and my skin is clear. I encourage anyone who has tried tons of creams, lotions, antibiotics and accutane with no results to try this pill and give it a chance to work.
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February 28, 2009

Pros:

this medication is a miracle. I used to have horribly oily skin and only after about 4 days of use (50mg twice a day), the oil is gone!!! I have a lot of small bumps on my forehead that i'm hoping Spiro will clear up as well.

Cons:

Needing to pee so many times a day

This drug is a miracle. Really. It works because it attacks the root cause of most oil and acne--> androgens. It blocks their receptors so that they don't have an effect. It'll work miracles if you have oily skin or hormonal acne.
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February 13, 2009

Pros:

Miracle Drug!!! Clears up acne, less oily skin and better
skin texture. Could feel it working quickly...

Cons:

Feel a little more tired than usual but well worth the benefits of
this medicine

I am 54 years old and have battled acne since a teenager. Was told I would "outgrow" this by the time I was 20.. Ha.Ha.!! Taken accutane twice and every antibiotic available. This is the ONLY drug that has ever helped to this degree. Guess what?? I discovered spiro on this website and my ob-gyn prescribed 100 mg. daily. I cannot believe the results..it is amazing!! Would love to hear from others my age to see how this drug is tolerated long term. My only regret is that I did not learn about spiro sooner. I would urge anyone who has persistant acne to try it. Now...how can I get rid of all these scars?
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January 26, 2009

Pros:

Glowing skin. Maybe one to two zits in the month

Cons:

Need to be next to a bathroom

I have nothing but praise for this life saver! The first 4-5 months I was on 25 mg then 50 mg per day and I did not see any improvements. It got worst in the amount of breakouts but the cysts were not has uge as before. Although I was warned about the possibility of the acne getting worst before it got better, after five months, I almost gave up and changed dermatologist. The new doc recommended 100 mg per day - and was willing to up the dose if no effects were noticed. At the next follow-up visit, the breakouts stopped. And right now after 8 months on this new dosage, I don't feel I have to put all the topicals (Tazarac, Hydroquinone) to removed the old scars, and spots. I am very grateful for this medicine that took me from 12-15 outbreaks to 1-2 a month...For those who are not yet seeing results, consult you MD for a higher dose. Not sure what I would do w/o spiro when I attempt to be pregnant. I was told I would to stop the meds bef attempting to get pregnant.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.