Antiandrogen
Reviews
4.1
1330 Reviews
Antiandrogen
Efficacy
68%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Antiandrogen
Side Effects
High
Antiandrogen
Acne.org’s Real World Take
“Spiro” has been shown to work in a real and noticeable way most of the time. However, messing with hormones is messing with hormones and it’s best to proceed with caution.
Antiandrogen
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Spironolactone
Compare To Other Treatments
5
51%
4
28%
3
10.1%
2
4.9%
1
6.1%

Used Spironolactone? Rate It:

Choose from 1 to 5 stars
January 19, 2015
Taking erythromycin and am going to take spiro
I have been taking erythromycin and tactuo gel for over 4 months and am seeing decent results but my derm recommended adding spiro. Wondering if anyone has tried this combo. Also concerned about the initial breakout when starting spiro but maybe the erythromycin will help with that. If anyone has any personal experience would love to know.
December 30, 2014
not sure
48bf skeptical about taking spiro long term went 8 months using trin/1% anyone taken this at this age
December 10, 2014
Starting this treatment next week
**will keep updating as I go** I will be getting married in 9 months. That being said I'm hopeful that'll give my skin enough time to a just to this medication. when i was in my teens (14) i started suffering from acne. i mostly had it in my T-zone with the occasional cystic out breaks on my forehead. at the time my reg. doc gave me a scrip for Duac. this ended up being the wonder drug for me! after being on it for two years, i noticed i had "grown out" of my out breaks and was easily treated with otc so i stopped taking the duac. Fwd to around 20 and i was getting more mild out breaks around my cheek area, my doc then decided it was hormonal and put me on a low dose Birth control pill to balance me. This set my skin over the edge! I've never been so badly and painfully broken out in my cheeks while on the pill. I had black heads, white heads, and cystic acne. I was on the pill for 3 months trying to give it a chance. i couldn't take it and stopped taking it. i then requested to be put back on the duac. unfortunately, duac isn't working as well as it did. it cleared up the black heads and the white heads about 85%, but not the cystic. my cheeks are starting to get a couple of "pits" and its depressing to look at. no amount of make-up will hide them... on top of it my skin has been very oily and my pores are enlarged. reading other reviews on this drug is giving me hope. most everyone else who is posting reviews on this, were having the same problems. my acne isn't as bad as most. i usually have around 2-3 cysts in my cheeks, the duac is keeping the white heads at bay. the cysts come around 1.5 weeks before my period and then finally subside after. then i'm for the most part "clear" of the cysts for about a week or so, till the cycle starts again. I'm nerves about the huge out break everyone describes, but I'm hopeful by summer my skin will finally be clear and i don't have to worry about doing a full face of make up any more.
November 22, 2014
20yo on Spiro feeling impatient
Hello so I will be 30 days on Spiro 50mg a day on 11/27/14 I haven't noticed an impact yet but I am trying to stay patient even though their are days I feel hopeless.. a bit of background of myself I will be 21yrs old in December I was on the birth control implanon (implant on arm) since 2012 of june recently got off of it in May 2014 because I wanted a break from b.c but I have never suffered from acne problems just the normal breakout (2-3 small ones a month) just started breaking out in the end of august 2014 lower of my face mild acne around mouth on jawline n chin so I figured it had to be hormonal sincr I got off the implanon so my gyno put me on orthotricyclen lo I been on that since Sept 21, 2014 but I still have mild acne on lower of my face get new pimples evevery day can SOMEONE give me SOME ADVICE OR SHARE THEIR EXPERIENCE WITH spiro. Please and thank you I have become so unhappy and my confidence has decreased alot! ************8months on pill Hello everyone so I have now been on spironolactone 50mg a day for about 8 months now i did have an initial break out but after the 4month on it i cleared up i didn't have any breakouts just a few small ones that werent noticeable i do still have my red n dark marks from post acne but recently i have noticed that i have been gettin new ones out of nowhere and Im scared that my skin will go back to what it was..I only missed one pill which was on april 27th so what i did was take 2 pills the next day since i missed one the day before..could that have anything to do with why im starting to break out? Can someone plz help me or give me some advice, im freakin out
October 26, 2014
Spironolactone as topical
Hi all!Iam 28, and I have pcos&insulin resistance and thyroid problems. I never eat sugar, have a special carbohyrate-diet with wholemeals, oat, fresh vegetables&fruits and meat, drink lots of water, tea, escpecially spearmint tea, because it's antindogenic. I take metformin xr and tryoid medicine, but my face, and my chest have bad, cystic acne. My doctor said my hormones are mostly ok, (except insulin and tsh ) so this is stress. I tried EVERYTHING,- even accutane & friends - but acne comes back. I didn't belive. :( In my country sadly spironolactone never used as an antiacne and antiandogenic stuff, so I can't try this :( BUT! I've got a pack of spiro, so decided to try to make a face-cream with it. Does is work? Have you ever tried spiro as topical on face? Did you ever tried to break the pills and rub it on face with some cream? Sorry if its stupid, but i havent got a better idea, to try spiro.
August 18, 2014
scared
I'm 15 & I've been going to a dermatologist for 3 years. I've tried every wash, every topical cream, even antibiotics to the point where he's said "we've tried everything." I want to take accutane but I have a tendency to acquire every side effect of every medication I take (the depression is a big factor.) My doctor just prescribed me Spirolactone & I should start it in a few days. After reading these reviews, I'm so hesitant. I'm dreading the initial breakout, I'm actually crying. I hate looking at myself, I feel so ugly, I've been getting made fun of since my acne started, I can't wear certain clothes because they don't cover it, I'm so self concious I barely wanna make eye contact, i spend so much money on makeup to cover it but it's still awful. The last thing I need is it getting worse. I'm so scared :(
June 30, 2014
HELP
3 months ago my doctor put me on a 50mg dosage.. to say the least it did not help with my acne at all it was all around my jaw line and forehead. about a month ago he bumped my dosage to 100mg a day (2 pills) and ever since then my acne got 100xs worse!! Its all over my cheeks and my neck. Does it get worse before it gets better? Should I wait it out? has this happened to anyone ? any info would be great
August 15, 2013
Works but not at first- its a dangerous drug

Pros:

Less oily
Lost 3 pounds

Cons:

HORRIBLE initial break outs for the first 3 weeks
Can cause damage to your body (make sure you get your blood work done every 3 months) and lead to cancer.
Must be dependant on the drug, stops working once you stop taking it

I am 23 years old and just started getting hormonal acne. In high school I had the odd couple break outs that I could usually use some sort of topical solution like differin and they would clear up. My skin would get use to these medications and they would become un effective so I would have to move on to the next treatment. My doctor prescribed me spiro 25mg 3 times a day (75mg/per day).Within the first couple of days I noticed my hair was not as oily and I could go 2 days without showering, which was unheard of before. I lost 3 pounds and I felt very weak and my breasts are super tender. It hurts when people hug me even. My skin started to break out in horrible huge cysts which had never happened to me before. This lasted for 2 and a half weeks. I am probably going to have to get laser therapy to remove the scars these will leave behind. I would cry, not leave the house and get strength from reading other reviews telling me I just had to wait it out. Now that I am in my third week I have noticed my skin clearing up and only a couple new smaller zits. Its also my time of the month so that could be contributing to this. I am going to keep at it for another couple months and wait to see the results. However I feel as though my acne was more manageable before I started this medication. I also researched it up and down (since I had to stay in on the weekends due too my embarrassment of the large pimples that were taking over my cheeks) and found out this medication is SERIOUS. You really need to watch your potassium intake or it could do irreversible damage to your liver and kidneys. I was up set my doctor never mentioned this and am going back so i can get blood work done(this is very important). Also i have read it only works while you are on the medication, its more of a band-aid than a cure. I am scared to go off of it because who knows what my skin will be like. I have also read reports that if you take this drug for a long period of time it can give you cancer. I would only suggest this as a last resort for desperate people. I wish I had been more informed before I started popping these pills.
May 6, 2013
just started and i see a major turn around i must be patient my DR. told me this will take time she has put me on a antibiotic for the mean time im not sure if it is this pill or the antibiotic but it seems to show
April 7, 2013

Pros:

my skin already looks better

Cons:

have to be careful about getting dehydrated

My face never broke out until I started taking birth control a couple months ago and this has already helped my face in a period of 48 hours! I just hope I don't get an initial break out in a couple of days :( the only thing I don't like so far is being so thirsty all the time

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.