Go on accutane. It doesn't matter if its hormonal acne, because what the drug does is permanently change the oil production of your skin which causes all acne. I'm one of the first groups ho took it in the 80s and I haven't regretted it in nearly 40 years.

You should read up on something called Estroblock. Heard it’s really helpful for adult severe acne. Let me know if you have any luck!

Hi HasiE82, I was just wondering what you decided to do with the Spiro? Have you continued taking it or did you stop? If so has your skin improved at all? I am also in my 30’s and have adult acne and have been on Spiro since mid-November and I am up to 100 mg which I’ve been on for a month now. I’ve seen very very minor improvements but I still wake up with new zits almost every day. It’s so so frustrating and so embarrassing. I’m a mom of 4 boys and I just can’t believe I’m dealing with this right now in my life. I have read countless reviews from women saying to stick it out because it can take up to 6 months to see results. That feels like a lifetime when we’re in the moment.... I do not believe Accutane is the answer either because it doesn’t not give lasting results most times. But I guess after Spiro it could be our only option.

weid(wo)man, sorry for responding so late but I just saw your comment on my post. Yes, I'm still on spiro. March 3rd will mark 4 months for me. This is what I can tell you: the wait is worth it! I had a terrible initial breakout around month 1 and my acne was worse than ever. To be honest, I didn't have as many cysts, whiteheads, and blackheads until I started my treatment with Spiro. In my case, my acne got worse before it got better. I would have 4 to 5 cysts and every day! And it seemed as if the spiro wasn't working at all. Everything changed for me at the 2 months mark. I stopped having cysts all together and would only get whiteheads (although it was still around 6 or 8 of time at a time, better than having cysts that take forever to heal). Once I hit the 2 months mark, with every day my face got better and I would get fewer whiteheads too. Now, I'm completely free of any spots on my face (knock on wood). My face is much smoother and the only thing I'm waiting for is for the hyperpigmentations to fade. I'm also using tretinoin 0.25% every night and that has been a gamechanger. I have absolutely no blackheads. They are literally all gone (my face used to be covered in them). All in all, I'm so happy with the results and am so glad that I stuck it out. I know how hard it is, trust me. However, these are my experiences and every person is going to respond differently to spiro. I hope it will work for you too. Best of luck and hang in there!

I understand the frustration. But I would encourage you to continue as long as you aren't experiencing any significant side effects. It took 6 months of taking 100mg for me to see results. At 4-5 months I remember feeling defeated, convinced there was no hope of positive results. Stick with it!!

It has also been 3 weeks since I've been on Spiro and I FEEL YOUR PAIN. I feel like my acne has gotten worse on my chin and jaw line as well. Thankfully the acne goes away after a few days but leaves me ugly scars. I am also taking 100MG a day taking (2) 50MG pills in the morning and one in the evening. Haven't experienced any side effects so I will just stick with it! Posts like the one posted by Michigan88 is what keeps my hopes up LOL. I am willing to wait 6 months as long as the results are great!

I take mine at bedtime, so by the time it "kicks in" I pee all day instead. Not ideal, but I can get a solid 8 hours in before my bladder wakes me up!

I feel for you. I'm currently 25 and I started getting really terrible acne when I turned 20. Like you, I had perfect skin all throughout high school. It started out as deep painful cysts on my face and I made the mistake of trying to pop them (trust me, don't) because acne was so new to me. I just wanted them gone. I found a dermatologist who prescribed me a few different types of antibiotics, one which worked well for a few months until I became immune. Birth control made it worse for me and I really didn't want to deal with side effects of accutane so I gave up and tried a holistic approach which included a complicated mix of vitamin supplements morning and night. For a while my acne got better, though it didn’t completely clear up. Then when I was 23 it came back with a vengeance. I began getting cysts on my upper AND lower back, my shoulders, and my hairline. I saw several dermatologists and none of them suggested anything new – until I saw my current dermatologist for the first time and she suggested spironolactone which I had never heard of before. She told me that it appeared as though my acne was caused by a hormonal imbalance. I started taking 200 mg a day for 2 months but stopped because nothing changed other than my periods becoming irregular. Once again, I gave up. A year later I went back to see her out of desperation. She put me back on spiro and told me to give it more time. I'm SO glad that I listened to her advice and gave it more time. I've been on spiro for about a year and a half now and my skin looks just as good as it did in high school. I have to tell you that it takes a while for your body to get used to it but DON’T GIVE UP ON IT! It took 2-3 months before my skin cleared up completely and 4-5 months before my period became regular again. Like some other users I also experienced light-headedness and occasional dizzy spells, but I soon found that dehydration was behind those symptoms. Spiro is a diuretic so it is extremely important to stay hydrated while you’re taking it if you want to avoid symptoms of basic dehydration. I’m not a doctor, but from years of similar personal experience and hours of my own research it sounds to me like your tiredness may be hormone related. Fatigue is a symptom of adrenal imbalance. The adrenal gland is where hormones including testosterone are produced. Since spironolactone is prescribed to counter the overproduction of testosterone (aka the hormone behind your acne) both your tiredness and your acne are probably signs that you’re dealing with a hormonal imbalance. If that is the case then the spironolactone should actually help with both as long as you give it time. I would still tell your doctor about the tiredness next time you see them though, because there’s always the chance that it’s from something totally unrelated. Hope this helps! Good luck!