Oral Retinoid
Reviews
3.9
2791 Reviews
Oral Retinoid
Efficacy
87%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Use with EXTREME CAUTION: Causes severe birth defects and fetal death.
Oral Retinoid
Side Effects
High
Oral Retinoid
Acne.org’s Real World Take
The nuclear option. It works reliably and provides long-term remission of acne, and even severe acne, in about ⅔ of people who properly take an adequate dosage. However, it permanently and irreversibly changes the skin and the body forever and users may experience long-term side effects for the rest of their lives. It’ll nuke it, but there is no going back.
Oral Retinoid
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Isotretinoin (Accutane®)
Compare To Other Treatments
5
37.1%
4
33.4%
3
15.5%
2
7.3%
1
6.6%

Used Isotretinoin (Accutane®)? Rate It:

Choose from 1 to 5 stars
July 28, 2008

Pros:

It did clear up my skin all together and the acne is not as bad as it was be4

Cons:

my acne did come back 3years later and i did have side effects

Would i go back??? well i'm trying EVERYTHING be4 i do go back as a last resort .... side effects:: Dry lips (very sore) and eye brows (flakey) my face did swell as well but i heard this is because my dose may have been to high!!! i do now have pains in my joints to the point i can't move have been 4 tests and scans and nuthing is "wrong" pain killers wont fix it i don't no 4 sure if this is to do with the drug but i have seen a few people who have the same thing as me and have also been on this drug...the only reason i would use this as a last resort is because i have had acne since the age of 12 and i'm now 22 by this point you do want to do ANYTHING to be acne free..
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July 6, 2008

Pros:

Makes acne better

Cons:

dry skin achey boness

Skin cleared up a lot all (not all completely gone)but only been on it 3 months i have felt depressed at times should i come of it ? what you think ?
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July 4, 2008

Pros:

Worked after 6 months. Cleared my skin for 5 months.

Cons:

Acne returned after 5 months. Dry lips and nose. Aching body.

Worked well for the time I was on it, as nothing else has worked. But as the acne returned wasn't really a point to it. Was very frustrating going through such a strong medication for little result. Furthermore, it is very toxic. However it works for some, and maybe I was one of the few it didn't work for :( I would say try it once if you are desperate, but don't go on another course if it doesn't work the firs time.
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June 29, 2008

Pros:

it cleared up my acne to a certain extent. i was one of the 10% of people who it didn't work completely for.

Cons:

super dry skin (face, lips, etc)

it was worth it, but it didn't clear it up perfectly. i still use the topical tazorac for breakouts.
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June 12, 2008

Pros:

Will get rid of all your acne and will make you look like you've never had a pimple in your life.

Cons:

Dry eyes and lips. Possibly contributed to minute hair loss.

I had really bad skin as a teenager. About 3 and a half years ago I took Roaccutane for 9 months. My skin cleared up completely. I then left school, travelled around Europe and North America, got married and did a whole lot of things that I never would've enjoyed if I was still covered in zits. My acne never returned and I've basically forgotten what it was like to have acne. Look after yourself while you're on it and you'll be fine.
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June 1, 2008

Pros:

Deinitely works. Acne free for about 2 years. Cleared my skin within the first month. I have never had more beautiful skin.

Cons:

Dry,dry,dry everywhere. Hair began falling out at three months. Immediately stopped taking Acutane. Hair began growing back after 6 months to a year.

I am considering going on Accutane again, as my acne has returned. I don't mind the dryness, but the loss of hair does scare me a bit.
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May 24, 2008

Pros:

Clear skin, smooth skin, smaller pores, never greasy hair

Cons:

chapped lips are the worst for me. i also have some red discoloration where my acne used to by that my doctor says is from the accutane and will go away. also sunburn and pealing face skin

My father had cystic acne in his teens and after two cycles of accutane he never had a zit again. I've had mild acne since I was 11. It was never particularly bad till I turned 15. It got worse and worse, and I had used sh*tty proactive, tons of over the counter, tons of prescription pills and prescription creams and none of it worked, one bit. Finally I got my doctor to prescribe accutane for me and i'm very glad I did. The side effects are a pain in the ass, but after about 2 and a half months i saw definite improvement in my skin. I'm on my fifth month now and today i woke up with my first zit in a few months. It's small though, not like my old acne. I'm very frightened that when I go off treatment it will come back, because my skin is so much clearer now. I'm on 80mg a day, which i think is the highest dosage.
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May 21, 2008

Pros:

Dried up my oily face and scalp, don't have to wash my hair every day, acne is getting better but still not where I want it to be. But doctor said it would get worse before it gets better

Cons:

Blood work, pregnancy tests, dry lips, dry face and scalp, back aches, and nose bleeds

I've been on it for about 6 weeks and I've noticed some improvement but not as much as I'd like. The side effects aren't fun but they are worth it for clear skin! Aquaphor has helped my lips and Cetaphil cream is great on my face! Still haven't solved the dry flaky scalp problem. Doc said acne would get worse before it gets better so I'm trying to be patient. I have friends and family members who took it and never had skin problems again!
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May 19, 2008

Pros:

Cleared my skin within the first week!

Cons:

Dry lips an eyes but when u see it workin like that u forget about the effects.

I never had acne untill i turned 17.It was the worst thing that happened to me.I tryed everything from Proactive to thousands of dollars to docter appotmants. NOTHIN WORKED! I was so frustrated that i lost all selfestem. Then one day i was reading a magasine an found how a treatment named accutane helped them get thire clear faces back.So i went an asked my doctor if i should go on it.HE agreed. The first week i saw major results the started dissapiring one by one each day it got better an better.By the 5 month my whole face was clear an under control. I have know been off it for 3 months an i feel great! I go out more an people complomns my face all the time. So dont wast any more time IF U HAVE ACNE GO ON ACCUTANE! its that simple.
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May 14, 2008

Pros:

NO ACNE! Clear skin, no bumps, really smooth, much smaller pores, not oily, less wrinkles, no redness, clear skin over whole body

Cons:

dry lips, dry eyes

if you have acne, TAKE ACCUTANE!!!!!!!! Do it! I'm 23 and used dozens and dozens of over-the-counter stuff, and many perscription pills and creams-- I finally took accutane, and I wish I would have done it when I was 15- It is the best acne treatment ever mande! I've been on it 3 months, and it is AMAZING! I really can't believe how much it has changed my appearance, confidence, and everything- I've wasted SO much time, effort, and money on stupid acne products that don't work! Over time I've spent probably $200 on proactive, $500 on perscriptions, and literally thousands on face washes and creams and lotions that have NEVER worked! And now it costs me $20 a month, for like 5 months and I don't have to use all that other junk, or spend any time applying stuff or worrying. Basically, you take 2 pills a day, and that's it. No more trying to make all those other products and regiments work.....PLEASE, if you have acne, TAKE ACCUTANE!!!! in my experience, it's the only thing that works!!!!
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.