Isotretinoin (Accutane®)
5
37.1%
4
34.1%
3
15.3%
2
7.3%
1
6.2%

Used Isotretinoin (Accutane®)? Rate It:

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July 23, 2014
bad Isotretinoin (Accutane) experience. causes depression, psychosis and thoughts of suicide
This a story of my own experience with the product. I'm still on it as i'm speaking and it has changed me drastically in the past year. I had mild acne for a period of 5 years. Nothing to woryy about and t seemd treatable with topic containing benzolperoxide and differin. A dermatologist said that i could take it but i wouldn't since i have know to people who got from it. They changed and bcame suicidal of it. After those five years the problem got a little worse and had to have clear skin to able to work and finish my studies so ti took the worst decision of my life in taking this product. This would avoid scarring. When collecting the pills at the phamacy, the phamacist told me he would not take such thing himself als he said the product brings risks and is not to be trusted. This was a promising start. I'm on the product for a year now and i feel worse than ever. I have serious mental problems since i began taking it. I pauzed the treament after 4 months for a month in order to take away the mental problems but it didn't work. They problems improved but will still there so the dermatologist talked me back into taking isotretoin. As i could control those toughts. After a month of intake i started to feel different, alone, i can't find enjoyment in anything anymore. I used to be a sportive person but ever since taking the accutane i had to stop because of serious joints muscle pain, headaches.. i feel like hiding and don't want to get out of the bed anymore. After just a normal day of working i am exhausted already. It feels lik my body and mind have aged 50 years in one year while on the isotretoin. I don't want see my friends aymore and don't seems to find satisfaction in any activity i used to love. Some days i sleep 18h of the 24h in a day... i feel like commiting suicide at least once a day.. This is the situation of the last months and i'm starting to blame the product, as i have never had mental problems with my acne. I just would not get it to me to much. As like everyone has something wrong and acne is quite common. his opions have changed drastically for the worse since i'm on the product. Thinking about the situation makes me easily agited and even hostile towards other people making remarks on it. I feel lonely, even when i was with my girlfriend or with friends, i could not relativise things that weren't a even an issue before.. I have thoughts of avoiding and hiding from my environment, the people around me. Feeling of alienation and nobody understands how it makes you feel. I feel anxious and sometimes agressive. Especially toward people who wronged me or talk on the acne problem to me.. They can't judge, because thay don't know how it changed since that first month. i feel hostile and agressive towards them even though they ment it for the best. Luckily i can keep it under control for now. The there are feeling of being sick because you take pills and go to specialsits. makes you feel even worse. I still take it because the Dermatologist promised me spots would go away eventually. They told me the acne would go away after on yer of intake of 20mg. The product is not effective at all because after one year i still have acne... It helps to clear most of it, but it still it is there and my skil still gets very oily. When i don't take it for 2 days, which i had to do when sick, the situation is back to off already. Now they said we should consider higher doses or another year at least of intake of this rubbish. Another year of this product will be the end for me i guess.. it's rubbish.. it makes me horrible and mentally worse than i ever felt before.. Desperate by the product and the fact it does not work as promised Accutane or isotretoin is a chemothrapy drug. A detail: i know A person who recieved chemotherapy in treatment for cancer. ( This "acne" medicine is still applied for treament of skin cancers, lung cancer and types of leukimia.) The person's treatment included isotretoin and the person suffered from the same mental and lonelyness reactions as me. Something Taking higher amounts is not workable for me on the mental and fysical plan. I feel 80 with constantly pain at my joints and muscles. After one year i haven't got any stable results.. but on the plan of and giving me strange rashes, very dry lips and shedding loads of my hair already it was very effective! I suffer from heavy stomach pain to. I guess this will be a race between the product working permanently or me commiting suicide because of the mental and fysic problems it gave me. Acne never got me depressed, The product did. I think i'm getting of it and hope i will get better. Acne is not worth commiting suicide for, but product isnt either. I Can imagine it has pushed many people over the edge who weren't reported as related to isotretoin or accutane. It almost got me to. But stil the doctor kept on saying this is a "safe product" that wouldn't harm me at all. They are too busy pointing that the depression is caused by the acne but not the product to give themselves a better conscience. In my case everything went wrong after taking it. I think i might go throug alternative treatments far away from those doctor with all thir poison pills. Skin cleaning with lasers or other methods. There are alternatives around
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June 16, 2014
Not worth it in the end (depression, IBS...no thanks)
I did Accutane once 10 years ago. Yes, it did help, but not much more than the run of the mill BP or prescription creams. It was not worth it in the end. It was expensive, the blood tests were more than a minor inconvenience (I'm terrified of needles), I had nosebleeds, etc... I don't know if the deep depression I was going through while on & for a few years afterwards it is a coinidence or not (there are studies saying that it does cause depression though). However, it's the aftermath a few years later that had me regretting this the most. Let's just say I didn't start having "bowel" issues until after this and I don't consider it a coincidence considering all the people who reported IBS after using Accutane. Needless to say, it wasn't worth it and I won't go on a second round. And some of the bigger side effects reported from other user's scared me too (like premature menopause). To be honest, Dan's regimen is working better than Accutane did. I'm giving Accutane 2 star. I would give it 1, but it did help a tiny bit temporarily I guess. The acne came back with a vengence about 2 years afterwards anyway. If it actually did 100% clear my acne and kept it away, I would actually give it 5 stars despite the bad side effects, because acne has had such a detremintal effect on my life from an emotional perspective. But it didn't make me clear, sooooo....no, I wouldn't recommend this.
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January 13, 2014
Made me lose hope

Pros:

I was clear when it was over for a short amount of time
Cheap with insurance

Cons:

Severly chapped lips & dry skin
Joint Pains & Headaches
Reoccurring acne after Accutane

So I tried A LOT of different oral anti-biotics and many different topical creams for my acne and nothing was working. I have moderate inflammatory acne and I told my dermatologist I would take anything at this point to get rid of it. She told me that Accutane is my best bet so of course I agreed. I'm only 14 and my mom was very unsure but she allowed me because she thought I wouldn't have to see the dermatologist ever again after accutane. Well, she was wrong. The side effects were awful. I had joint pain, headaches, and my lips were so chapped that people were asking me how I had crazy chapped lips in the summer.. By my last month (month 5 or 6), I was clear and all i had left were scars but that didn't last long. I do live a healthy lifestyle and work out at least 4 times a week and I have to say I do everything in power everyday to try to get rid of these nasty pimples on my forehead and they don't budge no matter what I do. My acne came back harder than I've ever had it. I have bigger cysts all over my forehead and pimples in places I've never had them in before. I wanted to get clear before my birthday in March but clearly that's not possible anymore.. Right now I'm on no pills but do use Acanya in the morning and Atralin at night, which don't work for me anymore. Seeing my dermatologist at the end of this month, praying there's something out there for me that'll actually clear my skin and keep it clear. I've been starting a dairy-free, wheat-free diet with water as my only drinking option and no junkfood. I've tried everything and I'm starting to think I'm going to have acne forever.
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January 12, 2014
Clears up skin but side effects can be v. severe

Pros:

Clears your skin up
Your skin doesn't even have blocked pores

Cons:

Side effects are severe
Can cause depression, irrational/suicidal thoughts
Sore joints (I couldn't run)

I went on Oratane (Accutane) for my stubborn, moderate acne. It cleared up my skin in 3 months (with an occasional pimple) and my skin's redness faded. Apart from the usual side effects, Accutane caused me to have suicidal/irrational thoughts and (being a sprinter this was awful) I was unable to exercise because my joints where so sore. I have been off it for a week and I feel much better. So, in conclusion, Accutane clears your skin up but you just have to think about if the side effects are worth it. Oh and I suggest going on Accutane only if you have tried every other method.
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November 23, 2013
Dissapointing

Pros:

Clears Cystic Acne
Pores look smaller

Cons:

Depression/Liver problems
Dry flaky skin
Acne comes back

I have suffered from bad cystic acne for about a decade. about 3 years ago I decided to take some time off from college and come home and give Accutane a shot. I was excited to see that my face was clearing up rapidly (I started on 30mg). However, I was constantly nauseous even though I was on a special diet. I also became extremely depressed. I would spend days at a time laying in the couch not being able to move. At this point my blood results were crazy and indicated that my liver was extremely irritated. I stopped treatment immediately for about a month, and then went back on it at 10mg. The side effects were pretty much gone except for super dry lips and dry skin. My skin was so dry that the soles of my feet would flake. After I finished the treatment, my skin looked amazing. I was happy to be done with acne forever. EXCEPT it came back about 2 months after I stopped taking the pill. First mildly, and within a year it was as if I had never done the treatment at all.
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June 21, 2013
Effective but not worth it

Pros:

Clears Acne

Cons:

Scarring
Hair Loss
Other major sideffects

Over the past years I have been suffering significantly from acne. Up until last year I managed to keep it at bay with minocyclin. Regretably, my doctor took me off it because he wasn't comfortable with such long treatments (past 1.5 years) and my acne came back. Instead he prescribed isotretinoin. I held out for half a year to just wait how my skin developed but after it kept getting worse, I started a treatment. Initially I was happy with the results and was suffering from few sideeffects (dry skin and lips, later dry eyes). However within 4 weeks I was visibly losing hair and I started to notice my acne scarring (it never scarred before even though it was much worse. And no, I did not manipulate it or anything). After 7 weeks I aborted the treatment due to feeling depressed, mainly about the scarring and hairloss. I have been of it for several weeks now. What is left is that my skin is a little better but I still get pimples while I have scars all over the place. My hairline has receded by 1-1.5 cm and my hair has gone from being super thick and having a nice texture to being able to having about 60% less hair, the individual hairs being much thinner and the hair itself feeling really dry. I would go back to my state before isotretinoin anyday! Please note that the sideeffects I experienced will not be experienced by everyone. However the possibility is high enough to pose a seriouse risk, so PLEASE read the forums and reports on this medicine before going on it! It is in no way a mirracle worker and while acne will go away over time, some of the sideeffects from isotretinoin may not. Also, I experienced all of these sideeffects with a rather low dose in a short period of time (first week 20mg per day, remaining time 40mg per day for 62-65kg, did 7 weeks of 26 week treatment)
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June 3, 2013
Just do it.
I spent years researching Accutane. At the point the decision was bothering me way more than the acne, I finally decided to take the plunge, age 24. Clearly everyone reacts differently. You won't know how your body will deal with it until you give it a go. I stopped after two weeks due to severely dry eyes. I mean seriously dry. I couldn't see and sometimes went whole nights without sleeping because the pain was so bad, and no products helped. Doctor said this was very rare, especially on my low dose of 20mg. But I don't regret it for a second. At this point, two months after stopping, my skin is mildly dryer, and my eyes are still pretty irritated in the mornings and evenings. But now that I know I will never touch the stuff again, I feel free. Now that my last resort has failed, I have accepted that I will have to get on with my life without perfect skin. So while this isn't an 'Accutane was the best decision I ever made' post, it's not a horror story. Give it a go.
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May 24, 2013

Pros:

Clears Skin Most Effectively

Cons:

Severe Side Effects Possible

Moderately severe acne has been a struggle in my life for quite some time. After over 10+ years of being prescribed virtually every antibiotic/topical on the market and in addition to trying many natural methods and diet changes, I went on the "miracle drug" known as Accutane. I did not take this decision lightly, and had read many reviews on both sides of the fence for this controversial drug. After signing the papers for iPledge and getting health insurance purely for this drug, I finally was prescribed 40mg per day for the first month. I was so excited to be on a drug in which my morning and evening routine were narrowed down to just simply washing and moisturizing my face. I felt much less nervous about my diet and things touching my face and it made a real life style difference that was amazing. Initially, my only side effects were very dry skin and chapped lips, two things that are easily manageable and worth the trade off of clear skin. My skin had virtually no active spots upon taking Accutane besides maybe two very tiny things that came to the surface for perhaps one day and disappeared, I experienced no initial breakout that others often talk about. Then, the unexpected happened out of nowhere. I started having very strange issues. I couldn't swallow very well, water and food was going down my esophagus slowly. My heartbeat was really noticeable at night when going to bed and often times would race or change speeds randomly. I felt a twitching my chest and ribcage off and on, and heart palpitations. Then, worst of all, I started to have a hard time breathing. My lungs felt a little tight and sore and I was struggling to keep my breath. All of this put me with different doctors, nurses, and a week of feeling I couldn't even be left alone. My anxiety was becoming higher and higher, and I couldn't focus with the physical symptoms and anxiousness. Ultimately, the doctors and dermatologist took me off the drug. Sure enough, within one week all of those symptoms either subsided or were greatly reduced. I didn't think I could fit in that small percentage of people with these serious side effects, but it happened to me and it was scary and real. I wanted so badly to continue regardless of the symptoms because I just want the acne to stop plaguing my life, but the breathing issues pushed me over the edge. This drug does in fact damage the physical state and the mental state for some people, and often times permanently. I am happy I made the decision to try it at the least, but I am confirmed in belief that although effective, Accutane is a serious risk. Sure, you can be lucky and have a wonderful experience that changes your outlook on life and confidence, and that is a blessing. On the other hand, there are thousands who have had the opposite result, or initially were cleared only to be left with major health problems down the line that can only be linked back to the drug itself.
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May 23, 2013

Pros:

Known as the miracle drug

Cons:

Maybe allergic to it
Numbness

After trying many products from antibiotics to topical treatments to chemical peels I have tried EVERYTHING for my acne to settle down but it clearly didn't want to at 18 with moderate to severe acne I had finally given up I then went to a dermatologist and got prescribed 40mg of Accutane every other day, so I took my first pill within an hour later half of my tongue and lip got numb so I went to my family doctor ( cause my dermatologist was unavailable ) and took me off it as a suspense of being allergic to it. Know after being on minocycline and tactuo which hasn't really helped much I might give it another shot. Any Suggestions? Highly recommend if you have tried everything. Try and take an allergy test before hand if you suspect that u may be allergic to it.
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April 13, 2013

Pros:

oil free, acne free skin

Cons:

delusions
impaired cognition
colitis
dry skin
schizophrenia

Try Lazer Treatment for Acne before you resort to this.. Ok so yes the effects of it were amazing although not permanent, I decided to not not through the full treatment, because it was literally making me stupid, and often throughout day I'd suddenly not know why I was where I was, my friend's mother took it and got ulcerative colitis for life, and schizophrenia, and I wouldn't be able to think straight, my grades dropped by 2 letter grades, so try everything else out first, you don't want to become acne free but get stuck with colitis for life...

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.