This a story of my own experience with the product. I'm still on it as i'm speaking and it has changed me drastically in the past year. I had mild acne for a period of 5 years. Nothing to woryy about and t seemd treatable with topic containing benzolperoxide and differin. A dermatologist said that i could take it but i wouldn't since i have know to people who got from it. They changed and bcame suicidal of it. After those five years the problem got a little worse and had to have clear skin to able to work and finish my studies so ti took the worst decision of my life in taking this product. This would avoid scarring. When collecting the pills at the phamacy, the phamacist told me he would not take such thing himself als he said the product brings risks and is not to be trusted. This was a promising start. I'm on the product for a year now and i feel worse than ever. I have serious mental problems since i began taking it. I pauzed the treament after 4 months for a month in order to take away the mental problems but it didn't work. They problems improved but will still there so the dermatologist talked me back into taking isotretoin. As i could control those toughts. After a month of intake i started to feel different, alone, i can't find enjoyment in anything anymore. I used to be a sportive person but ever since taking the accutane i had to stop because of serious joints muscle pain, headaches.. i feel like hiding and don't want to get out of the bed anymore. After just a normal day of working i am exhausted already. It feels lik my body and mind have aged 50 years in one year while on the isotretoin. I don't want see my friends aymore and don't seems to find satisfaction in any activity i used to love. Some days i sleep 18h of the 24h in a day... i feel like commiting suicide at least once a day.. This is the situation of the last months and i'm starting to blame the product, as i have never had mental problems with my acne. I just would not get it to me to much. As like everyone has something wrong and acne is quite common. his opions have changed drastically for the worse since i'm on the product. Thinking about the situation makes me easily agited and even hostile towards other people making remarks on it. I feel lonely, even when i was with my girlfriend or with friends, i could not relativise things that weren't a even an issue before.. I have thoughts of avoiding and hiding from my environment, the people around me. Feeling of alienation and nobody understands how it makes you feel. I feel anxious and sometimes agressive. Especially toward people who wronged me or talk on the acne problem to me.. They can't judge, because thay don't know how it changed since that first month. i feel hostile and agressive towards them even though they ment it for the best. Luckily i can keep it under control for now. The there are feeling of being sick because you take pills and go to specialsits. makes you feel even worse. I still take it because the Dermatologist promised me spots would go away eventually. They told me the acne would go away after on yer of intake of 20mg. The product is not effective at all because after one year i still have acne... It helps to clear most of it, but it still it is there and my skil still gets very oily. When i don't take it for 2 days, which i had to do when sick, the situation is back to off already. Now they said we should consider higher doses or another year at least of intake of this rubbish. Another year of this product will be the end for me i guess.. it's rubbish.. it makes me horrible and mentally worse than i ever felt before.. Desperate by the product and the fact it does not work as promised Accutane or isotretoin is a chemothrapy drug. A detail: i know A person who recieved chemotherapy in treatment for cancer. ( This "acne" medicine is still applied for treament of skin cancers, lung cancer and types of leukimia.) The person's treatment included isotretoin and the person suffered from the same mental and lonelyness reactions as me. Something Taking higher amounts is not workable for me on the mental and fysical plan. I feel 80 with constantly pain at my joints and muscles. After one year i haven't got any stable results.. but on the plan of and giving me strange rashes, very dry lips and shedding loads of my hair already it was very effective! I suffer from heavy stomach pain to. I guess this will be a race between the product working permanently or me commiting suicide because of the mental and fysic problems it gave me. Acne never got me depressed, The product did. I think i'm getting of it and hope i will get better. Acne is not worth commiting suicide for, but product isnt either. I Can imagine it has pushed many people over the edge who weren't reported as related to isotretoin or accutane. It almost got me to. But stil the doctor kept on saying this is a "safe product" that wouldn't harm me at all. They are too busy pointing that the depression is caused by the acne but not the product to give themselves a better conscience. In my case everything went wrong after taking it. I think i might go throug alternative treatments far away from those doctor with all thir poison pills. Skin cleaning with lasers or other methods. There are alternatives around

I'd had varying levels of acne since I was 12 and had exhausted every possible solution - antibiotics, topicals, birth control, gluten-free dieting, spironolactone, etc. Some of these treatments would improve my skin for a few weeks or months, but nothing ever lasted. Starting in my mid-20s, doctors started mentioning Accutane as a possible solution, but I'd heard such awful stories about it that I always resisted. Fast-forward to my 30th birthday. I had just gotten off spironolactone, which had worked marvelously for my skin but had also caused an allergic reaction. I decided that I was at the point that I would do ANYthing to finally and emphatically rid myself of acne, so I marched into my dermatologist's office and demanded Accutane. To put it briefly, Accutane was a miracle drug for me, and I experienced only the most minimal (and manageable) of side effects. I had to remain vigilant about skin/lip dryness, but so long as I moisturized faithfully and kept my lips slicked with Aquaphor, it was totally manageable - nothing worse than I experience during, say, a normal mid-Atlantic winter. I also experienced some joint and muscle achiness, but this was only inconvenient, not dehabilitating. At the four-month mark, my dermatologist noticed that my liver enzymes were starting to increase, so she reduced my daily dosage until I finished the course a month later. (They returned to normal after I ended the medication.) This had been my biggest fear - I didn't want to cause any lasting damage to my body - but the beauty of the monthly blood tests is that your doctor should catch any problems before they become irreversible. I've been off for five months now, and I haven't had a single cystic zit since; the worst acne I've seen is a few tiny, non-inflamed zits along my hairline that often pop up before my period. I would still describe my skin type as "oily," but it's not nearly as oily as it was pre-Accutane. And I've had no lasting side-effects or problems - I would absolutely do this all over again, and I feel silly for being so fearful of trying Accutane in the first place. My one key piece of advice: Try to find a dermatologist who is experienced with Accutane. I was fortunate enough to find a doctor who specializes in cosmetic dermatology, so she had the Accutane processes down pat - she told me exactly which cleansers and moisturizers to use, what dietary adjustments would help, etc. (She also put me on an awesome retinoid after, which has helped - along with at-home peels - get rid of the nasty scars and dark spots that remained after Accutane.) I had sworn to myself that I would post my experience with Accutane here, because I had stalked this message board for weeks before starting my course and found the information very helpful. I want to add to the chorus of voices who took Accutane successfully and are glad they did!

I went on Accutane back in August 2012 after suffering with mild-moderate acne for 3 years. I was on a 20mg dosage daily (which was eventually elevated to 40mg), and was on it for a total of 11 months. The first thing I noticed was my acne seemed to take a lot longer to clear up than most stories I'd read - roughly 9 months if I remember correctly. After the first couple of months on 20mg, my dermatologist increased the dose to 40mg, and that gave me really terrible side effects (nose bleeds, back pain, anxiety etc.), as well as a horrible breakout. My mild acne turned horrible on my cheeks - they were almost entirely covered in large spots. I put up with it, thinking it was some sort of initial breakout, but when it was still there about 9 months into the treatment, the derm put me back to 20mg. It was only then that the spots cleared up dramatically, and before I knew it, my face was 100% clear, as well as my back and chest. At the 11 month mark, I came off accutane, however 3 months later, my face begun to break out again. Another factor worth noting is my increase in anxiety, particular about how I looked in social settings. I would also cry at the drop of a hat and found myself spiralling into sad moods every now and then. Now, almost 2 years later, and my facial acne is just as bad as before I went on accutane, however, my back and chest have stayed 100% clear nearly all of the time. I'll be going on accutane again in a few weeks, which will hopefully finish off the job for my face. It works, but only to an extent. Stubborn acne (even if it's mild), may require a second or even third round of the medication.

The only reason I am not giving this 5 stars is because I have just had my last derm appointment and am yet to see what will happen when I stop taking this. Firstly I will say after 4 months I have only one or two very mild spots. Which considering what it was like before is amazing. I just want to share my experience because I know I did a lot of research before taking this. Pros: my skin has cleared up, it's amazing not to have oily skin, don't need to wash my hair constantly. Cons: dry skin: in particular my lips- stock up on Carmex & don't use Vaseline (it doesn't moisturise it creates a barrier.) I got mild eczema, small rashes, dry eyes (get eye drops!) I have in the last two weeks of medication had problems where when I go to the toilet it starts bleeding- this is because it must be drying up every where. Now that is quite a lot of cons but I STILL maintain it's been more than worth it & it's not been as bad as I was expecting. What I used to help my skin through the dryness- Cetaphil moisturiser & Cleanser, eye drops for dry eyes, home made manuka honey and aspirin face wash/ mask, hair masks, head & Shoulders shampoo & conditioner- (you will get dandruff), eve lom cleanser, Carmex, aloe protective restoring mask (body shop), Estée Lauder do a spot treatment that I found good, lancome tient visionarie (non comedegenic foundation), clarins instant smooth perfecting touch (as a primer -also non comedegenic) Things I learned- DONT use an exfoliating glove I took half my skin off doing this. DO moisturise as often as possible (on your body too! (I never moisturised before taking this so a routine for me has taken some time.. But trust me when I missed it out that's when I ended up with eczema. DO avoid perfumed products.- I made the mistake of taking the travel sized soap and glory stuff with me on holiday and ended up with eczema and rashes all over me- they are so perfumed. Don't spray perfume on your skin- Stick to your clothes- same Reason as above! Anyway hope this is helpful! X

I have moderate acne on my face since childhood.Now I am a 19 tear old male and It doesn't seem to go away.I consulted a dermatologist and she prescribed tetracycline,salicylic fave wash and climniskin gel.It worked for a while and after that I couldn't continue the treatment due to public exam and entrance exam.It stayed clear for a few days and now its back.I again consulted the dermatologist and She prescribed Clyndamycin gel,minocycline and salicilic face wash.After two weaks of no improvement I consulted her again and she prescribed ISO- TRETIN 10 which is a 10 mg tablet of ISOTRETINOIN.I have heard of this and extensively read about the drug.She prescribed these with ease.She didn't even mention about the side effects until I asked.Now I am on a cycle.of Isotretinoin on alternate days for two weeks.I asked her if I have to take it for six months and she said not at all necessary.I think my cycle will only be two weeks.I need to know If I will have any change in acne at all after using this...Please reply ......

I always had perfect skin as a child and teenager, right up until I was 18 and I went on the contraceptive pill. After 2 years on the pill I came off as I found that it made me very edgy, plus I wasn't in a relationship anymore and felt no need to continue with it. 6 months later, at 21, I had my first ever acne breakout and it was bad. It started with a few spots, then it covered my entire jawline (classic hormonal acne) the top half of my face was clear, the bottom half was covered in spots that kept coming back again and again. I took antibiotics for a year and tried various topical lotions, used expensive skincare products and herbal remedies, I even tried acupuncture but nothing worked until I went on Roaccutane. I am lucky that I have had an amazing dermatologist throughout the whole of this who has been able to shed some light on the situation; to cut a long story short - the contraceptive pill f**ked up my hormones resulting in adult onset acne. He was swift to get me onto a 3-6 month (it was 5 months in total) course of Roaccutane so as to avoid any deep scarring of the skin. He was strict about skincare products (I can only use oil free cleaner and moisturisers and avoid makeup, using mineral oil free matte powder and blush but no foundations or concealers) and I keep to this routine and try to avoid 'messing about' with different products too much. Roaccutane has been a harsh and difficult journey, I felt like sh*t when I was on it. The dry lips are a distant memory now, but I remember how awful they were (mine sometimes split at the sides and I reapplied lip salve, what felt like, once a minute!) I haven't suffered from any depression but I would feel a tiredness that I have never ever felt before and I can see how people become depressed by this, especially younger acne suffers (I was 23 on my course and felt strong enough to cope.) My whole body ached and I felt completely knocked out. I would come home from work eat and get straight into bed to just lie there or nap for hours and hours. I love the gym, and I found that my knee joints played up (I remember going for a 6 mile run, which would be a normal thing for me to do pre roaccutane, but 2 months into the treatment and I couldn't walk the next day after the run, a pupil at school helped me up the stairs like a woman four times my age - scary) so be prepared to have to completely take it easy and essentially live in a bit of a haze for the months of treatment.... My life was a weird blur during those 5 months, but I could see the light at the end of the tunnel as my skin improved quickly. Once off the drug, the redness, tiredness, chapped lips and joint pain all went away within 2-4 weeks. My honest advice would be - try other options first, research the drug, read up about it, talk to a dermatologist, think about the root of the problem not just a quick fix and be prepared mentally and physically for the treatment. I wish you all the love and luck in the world. Be strong.

I spent many years searching acne.org for solutions to chest and back acne. I tried everything from the Acne.org regimen to other prescriptions. Nothing ever cleared up my acne and I suffered with insecurity from the time I was 13 until I was 25. Finally I decided I had nothing to lose and started Accutane. The only thing I can say is that I wish I would have taken this sooner so I would not have missed out on a lot during my youth (swimming, beaches, etc.) The only side effects I experienced were an upset stomach the first week while my body adjusted to the meds. Of course, the chapped lips and dry nose are annoying, but you can learn do deal with it. I would rather have chapped lips than a breakout any day. It has been about 6 months since I stopped taking the medicine and I have not had one breakout. Accutane has improved my quality of life tenfold and I would recommend it to anyone who is considering it.

I started getting blackheads and whiteheads in elementary school so by the time I was entering high school I had full blown acne. It was more pustules than the deeper cystic acne, though I did occasionally get those too. My dermatologist gave me Accutane right away. This was over a decade ago now so it wasn't as big a deal like it is now. I believe I also started on the highest dose, 40mg 2x daily. During the entire time I was taking Accutane my face looked terrible! Red and flaky yet greasy from the A&D ointment I slathered on. The only side effects I had was dryness, skin, hair, mouth, eyes, nose you name it. I had blood and pregnancy tests every month without complication. I stayed on that dose only 3 of the 6 months I was supposed to because I had a vacation planned and didn't want to be a red flaky mess. I stopped the pills and as my skin came back from the dryness it was perfect! No spots, enlarged pores, excessive oilliness of my hair or face. My skin stayed in this perfect state until I was about 24. Even as my skin became oily again and I started getting clogged pores it did not return to the previous state until I turned 30 last year. So I have had, in my mind, 13 years of great skin for a few months of mild discomfort. I have struggled with lifelong depression and I didn't feel any worse when I was on the medication, having the hope of good skin actually made me feel better if anything. I would actually like to try another course/cycle of Accutane now that my acne has returned, perhaps not as aggressive as the first though. Accutane was a huge success for me and I wish more people had the same experience.

I did Accutane once 10 years ago. Yes, it did help, but not much more than the run of the mill BP or prescription creams. It was not worth it in the end. It was expensive, the blood tests were more than a minor inconvenience (I'm terrified of needles), I had nosebleeds, etc... I don't know if the deep depression I was going through while on & for a few years afterwards it is a coinidence or not (there are studies saying that it does cause depression though). However, it's the aftermath a few years later that had me regretting this the most. Let's just say I didn't start having "bowel" issues until after this and I don't consider it a coincidence considering all the people who reported IBS after using Accutane. Needless to say, it wasn't worth it and I won't go on a second round. And some of the bigger side effects reported from other user's scared me too (like premature menopause). To be honest, Dan's regimen is working better than Accutane did. I'm giving Accutane 2 star. I would give it 1, but it did help a tiny bit temporarily I guess. The acne came back with a vengence about 2 years afterwards anyway. If it actually did 100% clear my acne and kept it away, I would actually give it 5 stars despite the bad side effects, because acne has had such a detremintal effect on my life from an emotional perspective. But it didn't make me clear, sooooo....no, I wouldn't recommend this.

Best thing that ever happened to my skin. I was 16 years old when my derm prescribed this to me, since my moderately severe acne was not improving with topicals or oral antibiotics. I was about 5'6 and 115 pounds at the time so my dose wasn't heavy. I believe I was given 40mg every other day for the first month, then 40mg every day for the next two months, and then for the rest of my course it was 40mg everyday except on MWF I would take 80mg. Overall my course was 8 months and I never got completely clear. However, I saw major improvement and it's the most improvement I've ever seen with my skin (the regimen is a close second). I didn't really experience dry skin on my face, but my hands and lips were extremely dry. It definitely gave me my confidence back. I even got compliments on my skin! My skin was never oily, I didn't have any blackheads, and my cystic acne almost completely disappeared. I did have a few lingering clogged pores, which I believe was the reason why I still had a little acne. I'm 18 now and I was recently diagnosed with PCOS which causes oily skin and acne. I never took birth control pills while on accutane so my hormones likely intervened. After I finished the course my derm gave me differin but we didn't have insurance and my father spent a lot of money on the accutane, so I never got the prescription and I haven't been back since :( I used 2.5% BP and aloe vera to maintain my skin and it was decent for about a year. Did the regimen for half a year but quit to try oil cleansing and all that. Now my acne has completely transformed, in a bad way. I don't get cysts anymore but almost all my acne is pustules, whiteheads, and clogged pores. The regimen got me to a good point but I got lazy, wanted to try new things, and now my skin is worse than ever (still no cysts but I swear it looks worse than before accutane). So all in all, this medication gave me more improvement than any other skincare treatment, and I will be booking an appointment for my derm in the near future so I can take a second round. Oh, and I never get cysts anymore.