Intralesional Verapamil

Compare To Other Treatments

What Is It?

Verapamil is a drug that is normally used as an anti-hypertensive (anti-high-blood-pressure) drug. In the case of raised acne scarring, verapamil is injected directly into the raised scar in order to reduce the size and thickness of the scar. 

Verapamil is not always effective, and is normally used on small to medium sized raised scars. It is unknown, but suspected, that scars may sometimes grow back after treatment.

This procedure is normally repeated up to 8 times in 3-week intervals.

Results

Expand for result statistics
Scar Height Reduction
Average 47% reduction in scarring
Mean improvement in VSS total score
Average 44% reduction in scarring
Mean improvement in VSS pigmentation score
Average 40% reduction in scarring
Mean improvement in VSS height score
Average 53% reduction in scarring
Mean improvement in VSS pliability score
Average 51% reduction in scarring
Mean improvement in VSS vascularity score
Average 49% reduction in scarring
▸ Based on These Clinical Studies & Trials
▾ Based on These Clinical Studies & Trials
  1. Belie, O., Ugburo, A. O., Mofikoya, B. O., T Omidiji, O. A. & Belie, M. F. A comparison of intralesional verapamil and triamcinolone monotherapy in the treatment of keloids in an African population. Niger J Clin Pract 24, 986–992 (2021).
  2. Abou-Taleb, D. A. E. & Badary, D. M. Intralesional verapamil in the treatment of keloids: a clinical, histopathological, and immunohistochemical study. J Cosmet Dermatol 20, 267–273 (2021).
  3. Srivastava, S., Kumari, H. & Singh, A. Comparison of fractional CO2 laser, verapamil, and triamcinolone for the treatment of keloid. Adv Wound Care (New Rochelle) 8, 7–13 (2019).
  4. Aggarwal, A., Ravikumar, B. C., Vinay, K. N., Raghukumar, S. & Yashovardhana, D. P. A comparative study of various modalities in the treatment of keloids. Int J Dermatol 57, 1192–1200 (2018).
  5. Abedini, R. et al. Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars: a randomized controlled trial. Burns 44, 1482–1488 (2018).
  6. Zamanian, A., Nokandeh, M., Behrangi, E., Fazel, Z. & Zahra, A. Comparing efficacy and tolerability of triamcinolone and verapamil in treatment of hypertrophic scars and keloids. Journal of Skin and Stem Cell 4, 1–4 (2017).
  7. Uzair, M., Butt, G., Khurshid, K. & Pal, S. S. Comparison of intralesional triamcinolone and intralesional verapamil in the treatment of keloids. Our Dermatol Online 6, 280–284 (2015).
  8. Jannati, P., Aref, S., Jannati, A. A., Jannati, F. & Moravvej, H. Comparison of therapeutic response of keloids to cryotherapy plus intralesional triamcinolone acetonide or verapamil hydrochloride. J Skin Stem Cell 2, (2015).
  9. Ahuja, R. B. & Chatterjee, P. Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids. Burns 40, 583–588 (2014).
  10. Bilal, M. Clinical outcome of intralesional corticosteroid versus intralesional Verapamil in the treatment of post burn Keloid scars of the head and neck region. Pak J Surg 29, 263–268 (2013).

Side Effects

Side Effects
Low side effects and adverse reactions

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