What Is It?
“CROSS” stands for “Chemical Reconstruction Of Skin Scars.” A chemical peel, usually trichloroacetic acid (TCA), is applied directly on the area of the acne scar in order to maximize the effects of the chemical peel and to spare surrounding skin. During application, the chemical peel is applied by pressing hard for a few seconds, using a sharpened wooden applicator, until a white frosting appears. TCA concentrations greater than 50% increase the efficacy of the peel because of increased thickening of the skin and collagen production.
Good or Excellent Response
Strength of Evidence
65% of patients achieved a good (>50%) or excellent (>75%) improvement in scarring after 3 - 4 sessions
Moderate Response
Strength of Evidence
87% of patients achieved at least a moderate (>25%) improvement in scarring after 3 - 4 sessions
Side Effects
Medium
Medium side effects and adverse reactions