Topical Retinoid / Topical Antibacterial
Reviews
3.7
579 Reviews
Topical Retinoid / Topical Antibacterial
Efficacy
67%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Topical Retinoid / Topical Antibacterial
Side Effects
Low-Medium
Topical Retinoid / Topical Antibacterial
Acne.org’s Real World Take
A way of using benzoyl peroxide in combination with the topical retinoid, adapalene, that studies show works a bit better than benzoyl peroxide alone. Comes with side effects for the first weeks and can bleach fabric. Note: When used correctly, benzoyl peroxide on its own can completely clear the skin.
Topical Retinoid / Topical Antibacterial
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Adapalene / Benzoyl Peroxide (Epiduo®)
Compare To Other Treatments
5
38.2%
4
27.3%
3
11.1%
2
8.6%
1
14.9%

Used Adapalene / Benzoyl Peroxide (Epiduo®)? Rate It:

Choose from 1 to 5 stars
July 6, 2016
Miracle product
I have a long on and off relation with my acne..last year I finally decided to go to a dermatologist...he prescribed me clindamycin with phosphate in the day time and deriva-BPO(very similar to epiduo...but it contains adapalene as microsphere)...I followed the regime but didn't know that this is going to make my skin very sensitive to sun....so I ended up getting really red cheeks...and it looked almost like I have burned them...I felt itchy all the time though my pimples where gone but this thing was worse than acne... so I finally left it and decided never to use it again.... after some months I again started breaking out with small zits...all over my cheeks...and I decided to try castor oil to cure it....worst decision it didn't work..and of course got worse...I went all natural and tried treating my acne with vicco turmeric cream...it actually was helpful I reducing my acne...but of course u know natural process and products got to take their own sweet time...I suddenly realized that I had deriva-BPO and I can actually remove my acne if I use it properly...so very reluctantly I decided to give it a try...I use to do my basic CTM at night..and then apply a really hydrating mask from aroma magic... since I didn't wanted to use any moisture during the treatment...and take a really small amount..and spread it across the acne prone area...and the next day I was soo surprised with the results that I couldn't believe my eyes...that I am going to have clear skin finally... within two days guys most of my acne where gone.... believe you me....if you have moderate to mild acne just go for it...and remember during this treatment period... sunscreen must be ur best friend otherwise u r for sure going to burn ur face
This Was Helpful

6 user(s) found this helpful

Report
May 25, 2016
it works!
I got this from my dermatologist, LOVE IT! Gets rid of all of my acne without being too drying!
This Was Helpful

6 user(s) found this helpful

Report
May 22, 2016
This stuff work!!!!
About a year ago my skin was probably the worst shape It has ever been, It was all red and blemishy it had black heads and white heads, large amount of pimples and even pimples underneath my skin, they basically covered my face. Putting foundation and concealer on my face to try and cover it up made it worse, since I was blocking up my pores. I finally decided to see a derm since it was getting pretty bad. She recommended me epiduo, at first I was afraid since many people did say that this product didn't work and that it made your skin all flaky and dry, and it made your skin worse. The first few weeks I used it was pretty awful I broke out more, and my skin was all dry and red, and I was using this daily. Suddenly after like a month went by it started to work, my acne was gone. I had no more acne but I had scars from acne I was trying to get rid of before using epiduo. If you have skin that is just like mine then I would totally recommend this product. Epiduo can make a huge change in your skin.
This Was Helpful

6 user(s) found this helpful

Report
July 11, 2014
Good Stuff
Acne has been a problem for me. It was so thick on my cheeks I looked like a pepperoni pizza. It was gross! So, I saw my doctor and she prescribed Epiduo. I used it for a long time and it got rid of my break outs. But the thing was, I would always get them again. It would go away then in about 2 days a new one would come up. Last week, I found out the quickest and safest way to clear your face. Wash your face, put aveeno all over, apply epiduo on the face, then add tea tree oil on top of your face. The epiduo will dry out the acne and the tea tree oil helps kill it. The lotion just keeps your face moist. Sometimes you can breakout because of the weather. Ive been doing this whole process and my face has been clear. Im not kidding like this stuff is legit. If you follow this same process I'm like 98% sure it will work on you.
This Was Helpful

6 user(s) found this helpful

Report
June 4, 2013
Recommend

Pros:

Clearing my skin!
Preventing new breakouts

Cons:

Initial breakout
Takes patience
Can make skin dry

I've been using epiduo for just over two months now & I highly recommend it! However, during the 2-3 week stage I definitely felt like giving up. The initial breakout was TERRIBLE. I've never had any cysts before in my life & then suddenly day 16 hit & my face exploded. I basically saw no improved from that day onwards right until around day 50, & so I was disappointed as I began feeling like it was just yet another benzoyl peroxide product that doesn't work for me. I decided to stick with it & by day 66 I was hardly getting any new spots forming. At the moment (day 70), although my old scars are still there (which I'm praying will fade over time), I only have three active spots on my chin, which considering I used to have millions over my forehead & around my mouth & nose, it's a definite achievement in my eyes! My one & only criticism would be that I now have both dry AND oily skin. I've always ridiculously oily skin, but now I sometimes get dry patches as well which is a little awkward when knowing how much/what moisturiser to apply (when using epiduo I'd always recommend apply moisturiser day & night). I did experience a little bit of burning for the first week or so with a slight red tint to my skin, but nothing too major, & also my skin did become very dry for the first two weeks. I'm glad I persevered though! I also really recommend the epiduo app if you have an iPhone :-) p.s apologies for the lengthy review!
This Was Helpful

6 user(s) found this helpful

Report
March 15, 2013

Pros:

almost immediate results
lasting result
great for sensitive skin
odorless
easy to use

Cons:

slight dryness
somewhat expensive

I started epiduo when my dermatologist recommended I try it and gave me a few samples, I had acne on my back chest, and face at that time. I used it once and when I got out of bed the next day, my mother immediately commented on how well it had worked. even before I tried epiduo I was using aveeno moisturizer, but when I realized my skin was still a little dry, I switched to cetaphil I would recommend this for anyone, it is a definite life changer.
This Was Helpful

6 user(s) found this helpful

Report
March 7, 2013

Pros:

cleared my acne and scars
one tube lasts several months

Cons:

first month face very red, itchy
large scaley looking pores at first
developed contact dermatitis around eyes (I believe from epiduo getting on pillow case since I don't use near my eyes)

I have been using this product for over 4 months and it has cleared my acne completely. The first month was rough, but from month 1 - month 2, saw drastic improvement. Still had lots of redness, so I decreased usage to once before bedtime every other night. Only had one zit the week after I decreased dose, cleared quickly, been acne free ever since. I'm in my 30s and have been dealing with moderate to severe acne since around age 19. Tried numerous products, including accutane, all worked well at first then my skin would become twice as bad as before. I had given up on prescription products years ago, but after having children my skin became impossible to manage. I'm so glad I gave it a shot. I use cerave foaming facial cleanser twice a day, complex 15 face cream in morning, and skinceuticals phloretin c, also in the morning. Epiduo every other night.
This Was Helpful

6 user(s) found this helpful

Report
January 29, 2013

Pros:

Has cleared up ALL acne (including blackheads).
Skin is significantly less oily throughout the day.
Has faded my acne scars/red marks significantly.

Cons:

Very drying and itchy at first.
Horrible initial breakout - but I am using it in conjunction with spironolactone so the breakout may have just been caused by that.

This medication is wonderful and I'll probably use it forever. After two-three months I completely stopped experiencing the redness, dryness, etc. and all that was left was clear, soft, (almost) scarless skin! I'm extremely pale so red marks have forced me to wear lots of makeup whenever I see anyone outside of my family, but after 5 months using this medication I use concealer on maybe 2-3 faded spots and NO other face makeup. Having clear skin changes so much and the wait is so worth it.
This Was Helpful

6 user(s) found this helpful

Report
December 1, 2012

Pros:

Clears up acne FAST

Cons:

Mild stinging and peeling when you first start using it.

This works like a miracle! I was lucky enough to never suffer from acne in High School or college - I had near perfect skin. Once I moved to Manhattan I started breaking out from "adult acne." I tried everything, from duoc to a 6 month round of 80mg a day accutane. Accutane made my skin amazing and did help but some acne still came back about 10 months later. My DR put me in Epiduo and it has been amazing. I would def recommend that everyone try this product and stick with it because it is really amazing!! Keeps my skin clear and glowing!
This Was Helpful

6 user(s) found this helpful

Report
September 23, 2012

Pros:

Within the first few weeks it did clear my acne, then it all changed --- look at the con's....

Cons:

- Dried up skin so bad
- Burned my skin for the first few weeks
- soar-ness of skin and burning sensation.
- Made my acne 10 times worse!...
- not worth it!.

I went to my GP about my acne, i was getting down about having 10 spots roughly.. I was prescribed this treatment i regret the day i purchased this. The first couple of weeks i did see a massive improvement then the 2 week in initial break out occurred and i thought ok..fine!...then i thought it would go away and it did sort of but then 4 weeks in i went from 10acne spots roughly to 40!...left me with horrific scarring and my skin has been thinned out so much. I went back to my gp and she told me to use it still so i did for another 4 weeks and each morning i would wake up to another new spot that would only add to the scars. To me this product is not worth it anymore, it might be great for others but for my skin is was not... it made my acne 10 times worse then before, left with scarring and little open pores on my cheeks. I use this product only once a day and within 2 months my skin feels destroyed.
This Was Helpful

6 user(s) found this helpful

Report

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.