Bactrim/Septra : (trimethoprim-sulfamethoxazole) Oral Antibiotic

Brand:
Reviews
3.9
420 Reviews

Active Ingredients:
Sulfamethoxazole and Trimethoprim.

Inactive ingredients:
Docusate sodium 85%, sodium benzoate 15%, sodium starch glycolate, magnesium stearate and pregelatinized starch.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

5
40.5%
4
31%
3
14.8%
2
5.7%
1
8.1%

Used Bactrim/Septra : (trimethoprim-sulfamethoxazole) Oral Antibiotic? Rate It:

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April 22, 2011

Pros:

None, except it was cheap. Wish I could give it a negative "1".

Cons:

Hives/rash. Fever. Coughing. Shortness of breath. Headache. Nausea.

I had a severe allergic reaction to this antibiotic. I ran a fever for 5 days and on the 5th day broke out in a horrible rash from head to toe! Once the fever broke I began to feel the extreme itchiness of the rash. I was in agony for next 48 hours. No sleep and no relief. Finally doc got me on Medrol dose pack to calm it down. This was so unusual because I'm one of those people that can take any kind of medicine, eat anything, drink anything, without any problem at all. Well not anymore! Next step is Accutane I guess. I've maxed out all the antibiotic options (Doryx, Solodyne, Oracea). Wish me luck!
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November 23, 2009

Pros:

I have been Septra and Spirlactalone for about a year off and on. When I discontinue the medication the acne comes back. I have been on many different types of acne medication for about 20 years and this is the only one that has ever worked.

Cons:

Its an antibiotic so yeast infections are common (at least for me with any antibiotic)

IT WORKS WONDERS. It may not clear the small little pimples, but those are the least of my problems but it does keep them at bay. I don't get very many of those anymore. It takes care of the half dollar sized cysts that would take over my chin and cheeks for months at a time. I have a very old school Dermotologist and he is the first person to take me off the "childish" treatments other dermotologist had always put me on to treat my acne (which is no longer teenage acne). I have a feeling I am a lifer on the meds tho. (I don't mind as long as they don't cause life long problems)
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January 25, 2012

Pros:

DEFINITIVELY WORKS. I have been on it for a couple of weeks and within a week i could see noticeable differences. I have had maybe 4 to 6 new bumps on my face and within a day or two its almost like they are gone!!

Cons:

I have to take it twice a day and i forget to take it in the morning sometimes... haha. Haven't had a problem yet.

I have had acne since I was about 13. I had a normal amount of confidence in myself until I got acne and no one else did. I dealt with my acne for years using different antibiotics, ranging from tetracycline, minocycline, and most recently solodyn. Also i have been on plenty of topical like benzyl peroxide and others. I really let my acne take control of me by not wanting to go hang out with friends or do certain things because i hated when people would look at my acne and not at me! Now im 18 and im on this sulfamethoxazole, i am more confident than ever before and my acne is no longer an issue. Its a great product for those who dont have extremely bad acne, but yet still have noticeable bumps or pimples on their face. It helped me greatly!!!!
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December 20, 2010

Pros:

best acne med ive ever taken.
very effective with no side effects.
works fast.
worth the time and effort.

Cons:

pill is bigger than usual.
i broke out once i got off it but not severly.

take this if you have bad acne and have tried a whole lotta meds. side note: the depression people get when taking acne meds in my opinion is because you have acne and cant get rid of it or are scared to get it again or something to that effect. ive taken a buttload of pills and never became extra depressed. my depression always stemmed from the fact that i had acne.
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June 17, 2011

Pros:

Cleared me up

Cons:

Caused depression
Lost in appetite
Big capsules

I took this and Spiro for a month.Stoped for a week and had two big cystic acne. I then went back on it a week ago. Now I am suffering a lot of depression, emotional break downs, the blues. I think this medicine has caused this. :(
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February 4, 2016
Hi! How are you doing with everything? I know this was a long time ago, but I stopped spiro today and am starting Bactrim tomorrow to help with this breakout. Spiro caused me so much emotional pain and acne that I consider it one of the worst decisions of my life. Hope you are okay!
May 11, 2010

Pros:

Started clearing up my acne within the first week. So far I have been on it for close to a month and I have noticed a much faster healing times for the few pimples I am still getting. My skin is much less oily and I haven't had any cystic type acne all month. (Typically I get at least a few of those huge, painful ones every month)

Cons:

My stomach has been OFF. I am going to the bathroom several times a day, feel very bloated and gassy and have had some stomach aches. I have heard that long term use is also not recommended.

I have tried every cream, birth control pill and antibiotic, and so far this has been working the best for me. The only things I haven't tried are spernolactone and accutane. If the stomach problems continue, I may try an androgen blocking drug such as spernolactone before dealing with gas and constant bathroom breaks.
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August 21, 2010

Pros:

Cleared my skin instantly

Cons:

I am allergic to the product and it took me two weeks to find out, which was at work.

This product worked great for me at first but as soon as I had an allergic reaction things went down hill. I had a rash covering my entire body and couldn't stop myself from shivering. I had hallucinations at night and suffered from a slight depression. So I would say it's worth it if your not allergic because it worked great at first!
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February 24, 2012

Pros:

This stuff worked great for me...it kept my skin clear for about 2 years on a low maintenance dose. Very easy to take, no dry skin, and no side effects that I noticed.

Cons:

I had to give it up when I got pregnant, and cannot go back on it while I am nursing my baby. So, I had terrible skin while pregnant, and it's terrible now. Absolutely worth it for a healthy baby, but it's not much fun to look in the mirror.

I have had acne to varying degrees since I was about 13. I have tried everything, including accutane (which, for the record, did not really clear my skin, but the doc said it would sort of "re-sensitize it" so that things that previously didn't work may work after taking it). Once I finished the accutane, my doc put me back on low dose Bactrim. I told her we were wasting time because we tried it when I was younger and it didn't work. I was wrong. My skin was perfect in a week, and I was able to keep it that way by taking the Bactrim just once every other day!
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November 1, 2011

Pros:

works well to clear acne in short period of time; though tablet form is large, it dissolves rather easily in your mouth when divided into sections and taken with water (it seems flavorless, as well), i.e., if you have trouble swallowing pills, you can still take this drug rather easily : )

Cons:

possible development of allergy to drug; possible development of resistance to drug; adverse health effects resulting from long term use (esp. related to immune system, liver); big pill (but see "pros")

Bactrim worked great for me the first couple of times I took it for acne. It cleared my skin relatively quickly during the first two courses (about 10-14 days), but the third course was a complete failure and may have actually exacerbated my acne. Prior to the third course of Bactrim, I had never experienced any known allergic reactions to the drug. However, the third time I took it, about three weeks in, I developed a rash on my chest and behind my ears. I stopped it that day and never went back on the drug. The rash lingered for a couple of days, disappeared and then reappeared for a few days a couple of weeks later (likely because the Bactrim was still in my system). Meanwhile, my acne began noticeably improving (it seemed to only be getting worse while I was taking the Bactrim) and is nearly erradicated as I write this. (No, I do not believe Bactrim was the cause of my acne, but I do think it may have made it worse due to my apparent allergy to the drug). I attribute these signs of allergy to Bactrim because there was no other change in my lifestyle at the time and, indeed, the rash appeared right after I took the Bactrim and long before I had anything to eat that day. There really is no other explanation and rashes are apparently a common side effect of Bactrim (presumably b/c a lot of people are allergic to it). Overall, I think Bactrim is a great drug to take for a short term solution to your acne woes, but I would not say it is a permanent fix given its potential to lose its efficacy and the chance that you may develop an allergy to it over time. Also, long-term use of antibiotics appears to be damaging to the liver and may affect your ability to fight off future infections. I have been told by multiple pharmacists and doctors that Bactrim is one of the antibiotics you particularly do not want to become immune to given that is is used to treat so many different infections (all of which likely pose a greater risk to your health than acne).
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October 12, 2011

Pros:

NONE

Cons:

Gave me stevens-johnson syndrome, scariest experience of my life! i have never had drug allergies so I did not know what to think in the beginning. If this is an allergy you do not know you have this is how it works... The first day you take it you are fine- the second time your body develops IGE antibodies to make your body think something is attacking it, The comes the flu like symptoms---aches, terrible immobilizing pains, joint stiffness sharp pain, headaches, high fevers 102+ hives

cont... HIVES red bumps everywhere, itchy eyes, stomach cramping, nausea, diarrhea, weakness, shortness of breath. Even after I stopped taking it , it took over 5 days for the disgusting rash to even begin to disapear. Id rather have zits than die!
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