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I don't see how adopting such a routine is remotely realistic for the vast majority of people. No, but if this hypothesis were true, many people could influence their acne (and likely other long-ter...

So wait, are you saying usage of Retin-A may be worse than doing nothing for your skin? If the results of that table are right, then the more Retin-A you dump on your skin, the more skin cells in co...

Basically I have been depressed since I was 16, so 4 years, and coincidentally unable to concentrate well, memory loss etc... I doubt this is coincidence. When modern humans live in dim indoor light...

The mechanism described in the study cited requires interacting with the CD36 receptor on the keratinocyte. Since it appears that retinoic acid can upregulate CD36, this increases my skepticism that t...

So you've been experiencing a recurrence of acne since trying your DIY solution? To be specific, if I have a supersize Coke for both lunch and dinner (instead of just for lunch), then I started gett...

The problem with SAD lights is they seem to be insanely expensive (my DIY solution provides a LOT of light for $100 -- that's 6 4-foot bulbs), and none of the ones I've looked at offered any detailed ...

Medical Hypotheses is one of those 'quack' journals which carries no weight whatsoever. No, it's exactly what it states itself to be and serves an important purpose in the medical literature. I did ...

I've been taking the flush kind for a few days now and well I don't flush, at all. So, you're taking the form of niacin that is less safe, that doctors use to lower cholesterol, that has never been s...

Anything's possible, but nothing is proven along these lines AFAICT. But in a related note, on the ability of a low GI diet to influence the composition of the sebum:   The effect of a low glycem...

I'm pretty sure if you trawled through google long enough, you could probably find a success story involving acne and every supplement ever discovered/invented. No, by "literature" I mean scientific...

Thanks for the pointer; I'll definite have to get that article from the University, as the abstract seems to be saying two contradictory things. It's not clear I can significantly increase potassium i...

I now have 6 four-foot Chroma 50 fluorescent bulbs <= 4 feet from my eyes, but the extra bulbs have only been up for a couple days. I'm fairly convinced this is plenty to cause a noticeable and imm...

What benefits do you think copper and folic acid have for acne though? IMO, the copper is to cover their butts due to medical folklore that taking zinc might deplete you of copper. And, who knows, i...

(For adults only, since it's not clear it's been studied in kids, or that there's a known safety record for taking mega-doses of niacinamide for years on end.)   Since people are taking niacin (o...

to insure they got enough UVB and UVA for proper growth. I actually don't want any ultraviolet radiation, since the retinal ganglion cells that suppress melatonin don't respond to UV, so I could see ...

Before I lose it, I note this link:     which contains the claim about light intensity from fluorescent bulbs: You can only get about 1/5 of full sunlight intensity even at one inch from t...

Personally I can't think of any other reasons for this Well, the sun, of course. Unless you're saying you've repeatedly put on sunscreen on days when you stay indoors completely away from the sun....

My new $26 "light therapy" device has passed its first test. In later years, working indoors all day has made digestion a real struggle. Even cutting out sugar and caffeine in the evening often still ...

What should I do in the winter, when the light is dim even outside? I suspect the outdoor light is still bright enough, but I work with books and computer, so I can't manage to sit outdoors in the c...

I'm drawing from your conclusions that the intensity of light isn't as significant as being exposed to a real-light environment? These strange cells in the retina absolutely are intensity-sensitive;...

Would this be screwing up my melatonin cycle or is it not that big of a deal? I sleep in a very dark room and I dont wear anything to cover my eyes btw. Hard to say for any individual case. There ...

I was a lifeguard this summer. I was outside everyday for like 10 hours. Acne still stayed the same, the tan helped abit but not much. Interesting. So, you didn't wear hat or sunglasses when you wer...

1. So you're spending the entire time in daylight, then approx. how many hours is that? 14 hours awake, so 14 hours in daylight? At the peak of summer, I was spending about 10-12 hours outside each ...

Check this article out it says melatonin is a better antiinflammatory than any other antioxidant: Thanks for the article pointer, which had a couple points I hadn't seen before. What's missing the...

Melanoma has increased 50% in women but not men since these lasers hit the market in the 80's...Non melanoma skin cancer has tripled in women under 40... Taking a look at actual data , I see that the...