Acne.org Products
also ran into some interesting but hard to believe posts about something called Nobiletin. Jofo you may have some experience with this one. Didn't have much time to look into it in terms of effectiveness and practicality.
Both niacinamide and nobiletin (along with EGCg) are contained in the T-Zone Serum that I'm experimenting with right now. I've been using it twice a day for 20 days so far. I'll post an update if I notice any improvements.
Okay, so here's a quick update. I have seen quite a few things about niacinamide (Vitamin B3) applied topically to reduce oil. I must say this is one that I looked at awhile ago but never followed through with some trials, and I have to thank moderator AKL for reminding me of it.
It is very easy and actually pretty cheap to just buy some niacinamide powder in Bulk Form on amazon, and then just add it to a moisturizer or solution. I haven't had much time to look up the mechanism behind how it works, but I have seen studies confirming it's oily production reducing ability.
I also ran into some interesting but hard to believe posts about something called Nobiletin. Jofo you may have some experience with this one. Didn't have much time to look into it in terms of effectiveness and practicality.
My last midterms and finals are coming up, so I may be MIA for awhile. Physics III is threatening to absolutely destroy my GPA right now, so that is my number one priority LOL. But come summer time the niacinamide experiments will begin.
I look forward to your results. Have you ever considered trying something like b5 or vitamin a topically?
And I totally understand about school. I've pretty much been gone for weeks already. I'm in PHYS 182, and the class average is an F.
Okay, so here's a quick update. I have seen quite a few things about niacinamide (Vitamin B3) applied topically to reduce oil. I must say this is one that I looked at awhile ago but never followed through with some trials, and I have to thank moderator AKL for reminding me of it.
It is very easy and actually pretty cheap to just buy some niacinamide powder in Bulk Form on amazon, and then just add it to a moisturizer or solution. I haven't had much time to look up the mechanism behind how it works, but I have seen studies confirming it's oily production reducing ability.
I also ran into some interesting but hard to believe posts about something called Nobiletin. Jofo you may have some experience with this one. Didn't have much time to look into it in terms of effectiveness and practicality.
My last midterms and finals are coming up, so I may be MIA for awhile. Physics III is threatening to absolutely destroy my GPA right now, so that is my number one priority LOL. But come summer time the niacinamide experiments will begin.
I look forward to your results. Have you ever considered trying something like b5 or vitamin a topically?
And I totally understand about school. I've pretty much been gone for weeks already. I'm in PHYS 182, and the class average is an F.
Yea that's what I'm going to be looking into next. I see so much about various B-vitamins affecting oily skin, so I may try them in some form.
And yea for our last exam on Special Relativity the class average was a 54% 
Our next exam is on Quantum Theories, so that's going to be fun lol
4. Vitamin D Suppresses Sebocyte Cell Proliferation
From this article we see that a metabolite of vitamin D "resulted in a dose-dependent suppression of [sebocyte] cell proliferation, modulation of cell cycle regulation and of apoptosis" in vitro. To get this metabolite called calcitriol, vitamin D needs to be metabolized by the liver and then the kidneys. The article goes on to say that vitamin D is likely important for regulation of sebum production.
This article also says that vitamin D3 "induces time- and dose-dependent modulation of cell proliferation, cell cycle regulation, lipid content and IL6 and IL8 secretion by cultured sebocytes."
I am having difficulty finding actual clinical trials, but I did find this. It said that in mice, removing the vitamin D receptors[in sebocytes] resulted in a number of problems including enlargement of the sebaceous glands and development of epidermal cysts. It says their data imply that vitamin D receptors control collagen production, hair development and growth, and proliferation of sebaceous glands.
I think in our modern way of life, most of us are deficient in vitamin D. I know I am. If you have oily skin, I think getting some sunlight or taking some vitamin D3 is worth a try. I didn't find any clinical trials about its effectiveness at regulating sebum production, but you can easily find plenty of testimonials online.