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The Effects Of Topical Agent (Kelo-Cote Or Contractubex) Massage On The Thickness Of Post-Burn Scar Tissue

MemberMember
456
(@sirius-lee)

Posted : 01/27/2014 8:55 pm

An interesting article worth sharing:

 

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840175/

 

 

Abstract

 

Background

 

We conducted an experimental study to compare the effect of massage using topical agents (Kelo-cote or Contractubex) on scar formation by massaging the healed burn wound on the dorsal area of Sprague-Dawley (SD) rats.

 

Methods

 

Four areas of second degree contact burn were made on the dorsal area of each of 15 SD rats, using a soldering iron 15 mm in diameter. After gross epithelialization in the defect, 15 SD rats were randomly divided into four groups: the Kelo-cote group, Contractubex group, Vaseline group, and control group. Rats in three of the groups (all but the Control group) were massaged twice per day for 5 minutes each day, while those in the Control group were left unattended. For histologic analysis, we performed a biopsy and evaluated the thickness of scar tissue.

 

Results

 

In the Kelo-cote and Contractubex groups, scar tissue thicknesses showed a significant decrease, compared with the Vaseline and control groups. However, no significant differences were observed between the Kelo-cote and Contractubex groups. In the Vaseline group, scar tissue thicknesses showed a significant decrease, compared with the control groups.

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MemberMember
16
(@pursuit-of-happyness)

Posted : 01/27/2014 10:00 pm

that's seem to be good for people suffer from hypertrophic scars not atrophic scars , i also read studies about Chinese topical called mebo ointment ,it's work well with healing burns wounds , it's contain Sesame Oil ,Beta-sitosterol ,Berberine and other amino acids , i plan to to try it with micro needling , the problem that the topical contain powerful anti inflammatory agents and that's may effect the mechanism of needling that work by trigger controlled wound and inflammation is part of process , and that's may effect the outcome of needling !!

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MemberMember
456
(@sirius-lee)

Posted : 01/28/2014 3:53 am

Interesting. Is the mebo ointment widely available? Anyway keep us posted with your progress. As for me, I've only recently picked up copper peptide so I want to see how good it is before making the switch to something else. Otherwise, I'll be all over the map.

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MemberMember
42
(@leadingforce)

Posted : 01/28/2014 8:00 pm

oil usually clog pores

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