Acne.org Products
we speak in which scientifically it can make each substance:
Lugol or solution of Lugol is a diatomic iodine solution|I2 (1%) in balance with potassium iodide|KI (2%) in distilled water. It was appointed in honor the French doctor Jean Guillaume Auguste Lugol|J.G.A. Lugol
I ask. the potassium iodine or iodide as it can generate regeneration? it seems to me of science fiction, it is as to put an apple above of a scar and to say that it regenerates the skin.
God wants that this mistaking!
no more words guys, start treatment and then let see.
asked again : any news about juvista?
put eyes on 'decorine' <<< inhibition collagen, and cells can grow
pd: sorry my bad english .
'acell is a joke, i know , i hope all people knows '...
If ECM is non denatured, and the fibrils stay slender you will get site specific tissue. By the fact the intercellular cells can grow through the ECM. (When you are non wounded, the ECM in your body stay non denatured and you do not scar, your intercellular cells can pass through it)
So if it doesn't work then that means the ECM is denatured and has allowed crosslinking...
Trying to remain objective: The two Acell photos for me
1. No scar: The keloid one, you can not see any scarring. There could be some there, the picture may not have picked it up. However going on the picture: this shows the fibrils stayed non-crosslinked as you have site specific tissue with no scarring.
2. Scarring: The other picture of the MOHS, you can see scarring in the top half of the picture (bottom half seemed OK), therefor the ECM used was either denatured or become denatured which crosslinked the fibrils with excess collagen (i.e. you have scarring).
If the second one is the regular pattern I will not be using that type of ECM. If the keliod one was the regular result I'd use the ECM.
we speak in which scientifically it can make each substance:
Lugol or solution of Lugol is a diatomic iodine solution|I2 (1%) in balance with potassium iodide|KI (2%) in distilled water. It was appointed in honor the French doctor Jean Guillaume Auguste Lugol|J.G.A. Lugol
I ask. the potassium iodine or iodide as it can generate regeneration? it seems to me of science fiction, it is as to put an apple above of a scar and to say that it regenerates the skin.
God wants that this mistaking!
no more words guys, start treatment and then let see.
asked again : any news about juvista?
put eyes on 'decorine' <<< inhibition collagen, and cells can grow
pd: sorry my bad english .
'acell is a joke, i know , i hope all people knows '...
If ECM is non denatured, and the fibrils stay slender you will get site specific tissue. By the fact the intercellular cells can grow through the ECM. (When you are non wounded, the ECM in your body stay non denatured and you do not scar, your intercellular cells can pass through it)
So if it doesn't work then that means the ECM is denatured and has allowed crosslinking...
Trying to remain objective: The two Acell photos for me
1. No scar: The keloid one, you can not see any scarring. There could be some there, the picture may not have picked it up. However going on the picture: this shows the fibrils stayed non-crosslinked as you have site specific tissue with no scarring.
2. Scarring: The other picture of the MOHS, you can see scarring in the top half of the picture (bottom half seemed OK), therefor the ECM used was either denatured or become denatured which crosslinked the fibrils with excess collagen (i.e. you have scarring).
If the second one is the regular pattern I will not be using that type of ECM. If the keliod one was the regular result I'd use the ECM.
so, acell is ECM non denatured or not? perhaps if I above put decorin of acell to have better result...
maybe apligraf ECM non denatured ...I have approval regeneration in a photo here.
we speak in which scientifically it can make each substance:
Lugol or solution of Lugol is a diatomic iodine solution|I2 (1%) in balance with potassium iodide|KI (2%) in distilled water. It was appointed in honor the French doctor Jean Guillaume Auguste Lugol|J.G.A. Lugol
I ask. the potassium iodine or iodide as it can generate regeneration? it seems to me of science fiction, it is as to put an apple above of a scar and to say that it regenerates the skin.
God wants that this mistaking!
no more words guys, start treatment and then let see.
asked again : any news about juvista?
put eyes on 'decorine' <<< inhibition collagen, and cells can grow
pd: sorry my bad english .
'acell is a joke, i know , i hope all people knows '...
If ECM is non denatured, and the fibrils stay slender you will get site specific tissue. By the fact the intercellular cells can grow through the ECM. (When you are non wounded, the ECM in your body stay non denatured and you do not scar, your intercellular cells can pass through it)
So if it doesn't work then that means the ECM is denatured and has allowed crosslinking...
Trying to remain objective: The two Acell photos for me
1. No scar: The keloid one, you can not see any scarring. There could be some there, the picture may not have picked it up. However going on the picture: this shows the fibrils stayed non-crosslinked as you have site specific tissue with no scarring.
2. Scarring: The other picture of the MOHS, you can see scarring in the top half of the picture (bottom half seemed OK), therefor the ECM used was either denatured or become denatured which crosslinked the fibrils with excess collagen (i.e. you have scarring).
If the second one is the regular pattern I will not be using that type of ECM. If the keliod one was the regular result I'd use the ECM.
so, acell is ECM non denatured or not? perhaps if I above put decorin of acell to have better result...
maybe apligraf ECM non denatured ...I have approval regeneration in a photo here.
From my personal understanding, Decorin would keep the fibrils slender, stop excess collagen build up (scar) which would enable the intercellular cells to grow through the ECM.
I've seen the apligraf photo and you can see scar free healing.
we speak in which scientifically it can make each substance:
Lugol or solution of Lugol is a diatomic iodine solution|I2 (1%) in balance with potassium iodide|KI (2%) in distilled water. It was appointed in honor the French doctor Jean Guillaume Auguste Lugol|J.G.A. Lugol
I ask. the potassium iodine or iodide as it can generate regeneration? it seems to me of science fiction, it is as to put an apple above of a scar and to say that it regenerates the skin.
God wants that this mistaking!
no more words guys, start treatment and then let see.
asked again : any news about juvista?
put eyes on 'decorine' <<< inhibition collagen, and cells can grow
pd: sorry my bad english .
'acell is a joke, i know , i hope all people knows '...
If ECM is non denatured, and the fibrils stay slender you will get site specific tissue. By the fact the intercellular cells can grow through the ECM. (When you are non wounded, the ECM in your body stay non denatured and you do not scar, your intercellular cells can pass through it)
So if it doesn't work then that means the ECM is denatured and has allowed crosslinking...
Trying to remain objective: The two Acell photos for me
1. No scar: The keloid one, you can not see any scarring. There could be some there, the picture may not have picked it up. However going on the picture: this shows the fibrils stayed non-crosslinked as you have site specific tissue with no scarring.
2. Scarring: The other picture of the MOHS, you can see scarring in the top half of the picture (bottom half seemed OK), therefor the ECM used was either denatured or become denatured which crosslinked the fibrils with excess collagen (i.e. you have scarring).
If the second one is the regular pattern I will not be using that type of ECM. If the keliod one was the regular result I'd use the ECM.
so, acell is ECM non denatured or not? perhaps if I above put decorin of acell to have better result...
maybe apligraf ECM non denatured ...I have approval regeneration in a photo here.
From my personal understanding, Decorin would keep the fibrils slender, stop excess collagen build up (scar) which would enable the intercellular cells to grow through the ECM.
I've seen the apligraf photo and you can see scar free healing.
Seabs, can we get this, or is this something a doc has to do? How is it actually used?
we speak in which scientifically it can make each substance:
Lugol or solution of Lugol is a diatomic iodine solution|I2 (1%) in balance with potassium iodide|KI (2%) in distilled water. It was appointed in honor the French doctor Jean Guillaume Auguste Lugol|J.G.A. Lugol
I ask. the potassium iodine or iodide as it can generate regeneration? it seems to me of science fiction, it is as to put an apple above of a scar and to say that it regenerates the skin.
God wants that this mistaking!
no more words guys, start treatment and then let see.
asked again : any news about juvista?
put eyes on 'decorine' <<< inhibition collagen, and cells can grow
pd: sorry my bad english .
'acell is a joke, i know , i hope all people knows '...
If ECM is non denatured, and the fibrils stay slender you will get site specific tissue. By the fact the intercellular cells can grow through the ECM. (When you are non wounded, the ECM in your body stay non denatured and you do not scar, your intercellular cells can pass through it)
So if it doesn't work then that means the ECM is denatured and has allowed crosslinking...
Trying to remain objective: The two Acell photos for me
1. No scar: The keloid one, you can not see any scarring. There could be some there, the picture may not have picked it up. However going on the picture: this shows the fibrils stayed non-crosslinked as you have site specific tissue with no scarring.
2. Scarring: The other picture of the MOHS, you can see scarring in the top half of the picture (bottom half seemed OK), therefor the ECM used was either denatured or become denatured which crosslinked the fibrils with excess collagen (i.e. you have scarring).
If the second one is the regular pattern I will not be using that type of ECM. If the keliod one was the regular result I'd use the ECM.
so, acell is ECM non denatured or not? perhaps if I above put decorin of acell to have better result...
maybe apligraf ECM non denatured ...I have approval regeneration in a photo here.
From my personal understanding, Decorin would keep the fibrils slender, stop excess collagen build up (scar) which would enable the intercellular cells to grow through the ECM.
I've seen the apligraf photo and you can see scar free healing.
Seabs, can we get this, or is this something a doc has to do? How is it actually used?
It is not for sale in any pharmacy were I live. Someone posted up a link on the decorin thread were it had a price.
What I've learned is decorin is a protein that is found in every unwounded tissue in your body, but it is more or less absent in wounds. It decorates the ECM and stops your non wounded tissues from becoming fibrous.
It has been shown to stop the fibrils from over expressing collagen (scar), so following logic if you apply it onto a wound that is in the process of laying new ECM, it would stop the fibrils from over expressing collagen.
BTW I'm no expert, I just follow what I have learned for myself like we all should.
hi all,
i'v posted this link in another thread, but i think it's interesting here too.
It's about medical needling and it's relationship to regeneration.
maybe someone finds it elucidating.*g*
i don't know.
so long
NEO
Hello
I am also interested in the Lugols Iodine . i want to try on a small scar on my face but BRD warned us about long term iodine use and the potential dangers in another thread. however, i've heard more than a couple people, outside of the canadian doctor that say this stuff works from the bottom up.
if anyone has seen results with this ..i know this is fairly new here....please let everyone know..the regeneration of scars with iodine is worth investigating and yes perhaps we can start another thread with this topic.
one question the stain should not persist..how do we remove the stain..hopefully the stain will not become a permanent problem when other cleansers are used?
Thanks guys
Best of Luck to all ! 
Ok I've been reading all the posts recently.
I started this scarless healing thread back in 2007 and now we are approaching 2010.
So where does scarless healing stand.
The best option I see is still acell. I believe that doctor Jones needs to try another
patient as quite clearly it shouldn't have crusted over as it did and needed to be kept moist.
Acell now shows on its website http://www.acell.com/pandr_surgery.php
"ACell, Inc. has developed a proprietary line of plastic surgery and wound care devices utilizing an advanced regenerative medicine technology. ACellas MatriStem technology is a naturally occurring bioscaffold derived from porcine tissue. When MatriStem is placed into a surgical site or wound, it is resorbed and replaced with new native tissue where scar tissue would normally be expected."
Is everyone just waiting for others to try it out? The product is there so what is causing the lack of take up?
acell is a joke, is a publicity so that the actions of acell raise with lies (the same happens with juvista) the only thing that can give something of hope is the protein decorin, and I have seen a photo treatment scarless with apligraf but not sure...
I believe that juvista this giving the awaited results but is not a hope, by the way is necessary to hope until the 2011 to see the results of phase 3, and for when on sale officially this product?
acell is a joke, is a publicity so that the actions of acell raise with lies (the same happens with juvista) the only thing that can give something of hope is the protein decorin, and I have seen a photo treatment scarless with apligraf but not sure...
I believe that juvista this giving the awaited results but is not a hope, by the way is necessary to hope until the 2011 to see the results of phase 3, and for when on sale officially this product?
We've seen one photo of could be complete scar free healing with acell and one with a bit scarring in it done over a biggish surface area.
It is still early days and is a mixed bag IMO
Anyway if you can have a non denatured ECM you will get scar free healing. The ECM on your unscarred tissue is the result of non-denatured ECM which has masses of the protein decorin keeping the fibrils non-crosslinked...
What we need is non denatured ECM.
The appligraf photo is a precedent to what we want.
acell is a joke, is a publicity so that the actions of acell raise with lies (the same happens with juvista) the only thing that can give something of hope is the protein decorin, and I have seen a photo treatment scarless with apligraf but not sure...
I believe that juvista this giving the awaited results but is not a hope, by the way is necessary to hope until the 2011 to see the results of phase 3, and for when on sale officially this product?
We've seen one photo of could be complete scar free healing with acell and one with a bit scarring in it done over a biggish surface area.
It is still early days and is a mixed bag IMO
Anyway if you can have a non denatured ECM you will get scar free healing. The ECM on your unscarred tissue is the result of non-denatured ECM which has masses of the protein decorin keeping the fibrils non-crosslinked...
What we need is non denatured ECM.
The appligraf photo is a precedent to what we want.
in my country an outstanding scientist that already is 72 years old and continues responding my email q has the same question ' when the tests with humanos' begin;
invention already for many years a colageno membrane, this difference of others in which he is ' direccionado' that is in theory direccion the colageno fibers unfortunately for want of bottoms the tests in humans not yet are realised not if this membrane that direction the colageno could to avoid that the colagen of the skin grows, and that allows the cells to grow, giving like result nonscar.
as always, to wait for and to wait for another option do not have
the page is in Spanish but the control translated to English:
http://www.translate.google.es/translate?h...julio%2F105.php
so that in fact we have 2 problems.
1: to avoid that it grows colageno fibers
2: the address...
this causes that the new skin grows equal q was before, without interlaced fibers of colageno like this in the normal skin. can't the skin not to grow normal.
it seems that the membrane that I put in the Link point 2. is no another product that direction the colageno like in the normal skin. as it is this membrane of the Dr. Grigera
pd: sorry my bad english (i know).
All these treatments seem to be on the table, but either no one uses it or they just don't really do anything, and we are not being informed if that's the case.
But if some of you need to know how scarless healing works, here is something I came accross while bored.
http://www.thenakedscientists.com/HTML/con...interview/1133/
All these treatments seem to be on the table, but either no one uses it or they just don't really do anything, and we are not being informed if that's the case.
But if some of you need to know how scarless healing works, here is something I came accross while bored.
http://www.thenakedscientists.com/HTML/con...interview/1133/
I commit myself, that you have the same deception that I, and want answers like I. I commit myself to put photos of before and after treatments that doa but like your and other few users of this foruma.I those that really are worth the pain. .on this post of the forum is where better the subject struggles, lamentably we do not have tools to experiment.
i mean I itself hoping to have in my handsadecorin, a ECM not denatured, juvista, and the membrane of colageno of the dr. grigera .
those are my 4 pillarsa
that I believe that it is the solution! --------------at least the ECM not denatureda with much decorin above (200 nm). ------------ <<< the real grial im pretty sure
believe me brother if I have some of those things in my handsa I commit myself to put photos of before and latera but until not having thata.don't mention it he serves. only desire that the years happen flying to accede to these new medecines that just now are discovereda is not of another one. I am delay
and the Link that you have put speech of ' osteoporin' and if. imagine, in a wound. to.have a revision and to put, my serious ideal:
a ECM not desnaturalized, decorin 200nm, an injection of juvista (tgf3), and a gel with a osteoporin inhibitor. lol. that if serious the great grial
sometimes i like me to study Biology to be able to know how to use these drugs and to be able them. .o in its defect to ask to him to a biologist that helps me
sorry m.bad english.
acell is a joke, is a publicity so that the actions of acell raise with lies (the same happens with juvista) the only thing that can give something of hope is the protein decorin, and I have seen a photo treatment scarless with apligraf but not sure...
I believe that juvista this giving the awaited results but is not a hope, by the way is necessary to hope until the 2011 to see the results of phase 3, and for when on sale officially this product?
We've seen one photo of could be complete scar free healing with acell and one with a bit scarring in it done over a biggish surface area.
It is still early days and is a mixed bag IMO
Anyway if you can have a non denatured ECM you will get scar free healing. The ECM on your unscarred tissue is the result of non-denatured ECM which has masses of the protein decorin keeping the fibrils non-crosslinked...
What we need is non denatured ECM.
The appligraf photo is a precedent to what we want.
in my country an outstanding scientist that already is 72 years old and continues responding my email q has the same question ' when the tests with humanos' begin;
invention already for many years a colageno membrane, this difference of others in which he is ' direccionado' that is in theory direccion the colageno fibers unfortunately for want of bottoms the tests in humans not yet are realised not if this membrane that direction the colageno could to avoid that the colagen of the skin grows, and that allows the cells to grow, giving like result nonscar.
as always, to wait for and to wait for another option do not have
the page is in Spanish but the control translated to English:
http://www.translate.google.es/translate?h...julio%2F105.php
so that in fact we have 2 problems.
1: to avoid that it grows colageno fibers
2: the address...
this causes that the new skin grows equal q was before, without interlaced fibers of colageno like this in the normal skin. can't the skin not to grow normal.
it seems that the membrane that I put in the Link point 2. is no another product that direction the colageno like in the normal skin. as it is this membrane of the Dr. Grigera
pd: sorry my bad english (i know).
If I interpret you correctly, this sounds like decorin all but in name.
Decorin what it does:
It stops the fibrils in our collagen from over expressing collagen (scarring). At 200nm has completely stopped the collagen over expression in a keloid situation.
When the scarring response has been stopped by decorin, this enables the intercellular cells to crawl through the slender collagen fibrils to create the site specific tissue they intercellular cells do in our non wounded and non scarred tissues.
i need find decorin and tgf b3, that 2 things i think is solucion...the key is to be able to these drugs proteins to begin to prove them. it would want to be able to obtain to decorina and tgf b3 but not who can make that to me.
My apologies if I sound like a broken record here... But I just thought I'd repeat it to pass on information
Regarding decorin, without decorin your tissues build up excess collagen (scar) on the fibrils; on the other hand if you have adequate decorin levels your fibrils stay slender and you do not scar.
Decorin has completely stopped fibroblasts over expreessing collagen at 200nm in a keloid, at the same time in the normal tissues it didn't create mass apoptosis (i.e. cell death).
Decorin levels are extremely low is new wounds, but found by the bucket load in non wounded tissues. They are almost non existant in burns.
Another little bit of information, after exercise when your muscles have been damaged, in order to cut fibrosis your musles over express decorin, this helps to enable your muscles to rehabilitate without fibrosis.
Eterna I do not know were you would get a hold of yje proteins you need but I wish you luck.
I think TGFB3 will be out soon. But I'm not to sure, I'm not to up to date on that protein.
Heres a link, matristem has regenerated hair:
http://www.womenshairlossproject.com/hair-...lly-clone-hair/
Heres a link, matristem has regenerated hair:
http://www.womenshairlossproject.com/hair-...lly-clone-hair/
Okay, so they have proven that the hair can be regenerated through a previous site where hair could not be regrown. But when will it reconnect to their brain that that means it can be used for acne scars, and thus a treatment for scar sufferers can be done?
I spoke with my doctor about the stem cells. HE SAID POINT BLANK IT IS A LONG WAY OFF. hE ALSO SAID THAT THEY've been regenerating limbs and fingers, etc.. with the stem cell techniques for years and none of it has hit market yet. He was not all impressed and not promising at all for it ever hitting market and making any significant difference in acne scars. So, now I have no more hope and have stopped thinking about this.