New Acell photos are up on Dr. Jones' site

 

1.) This is an illustration of what appears to be a run-of-the mill hair follicle like what you'd find in arm skin or on the head, etc (actually the thick hairs on our head tend to go deep into the subcutaneous layer).

 

The context of the picture is facial skin. This diagram is pretty much the same diagram I have found in my physiology and pharmacothearpy textbook about acne.

New pictures right on. Although there's only one. So I guess new picture. It's hard to tell because the picture is not from the same angle as the other one, but it look much improved.

i'm curious, has anyone posted a Q&A with mr. manning from acell? if not, would anyone be interested in compiling one? i have not spoken with him, but have one particular question: how does acell handle pigmentation in regenerated skin?

i'm curious, has anyone posted a Q&A with mr. manning from acell? if not, would anyone be interested in compiling one? i have not spoken with him, but have one particular question: how does acell handle pigmentation in regenerated skin?

As far as pigmentation goes, that's not something I'm hugely concerned about. Take a look at this product: http://www.microskin.com.au/ Unfortunately it's only presently available in Austrailia and costs $700 for the whole kit for facial spraying ($3000 for full-body). It's actual skin cells that match your skin tone that you spray over your skin. It looks totally natural, stays on for 3-4 days, hair can grow through it, and it's waterproof. Pretty cool!

Holdontohope ECM material can be denatured. It could have been denatured accidently and if it was youad get a fibrotic response and people spinning it a certain way maybe to fuck up Acells standing.

Anyway every tissue our body has is very clever, tissues have been regenerating with ecm for thousands and thousands of years.

To every tissue, ECM is kind of like a 3d book, a manual. If page 26 is glued together it cant access the information on page 26 and we get more of a fibrotic response. If pages 36, 37 are glued we get more of a fibrotic response and so on. And if the whole book is glued togethera

Renovo is going to start testing Juvista on scar REVISION this December.

http://clinicaltrials.gov/ct2/show/NCT00742443

Well at least they are trying to test it on REVISION instead of prevention.

The scars are going to be excised, then sutured up with Juvista.

Oh yeah and don't think you can get included to the study because you are excluded if the scar is "within 3 cm of another scar"

Hopefully outcomes will be good and we can add Juvista to our already very limited arsenal.

^ thats interesting !

Atleast there are things coming in few years. I just hope that they really work.

So it seems to me that the concept of acell and juvista is almost the same. Get the scar excised and use one of them to get a scarless healing, or am i mistaken?

A possible dark horse:

http://clinicaltrials.gov/ct2/show/NCT0065...%22&rank=16

These clinical trials and approvals from the FDA sure take a long time to complete.

The updated pics are nice, theres some good improvement. But, they say complete healing takes months. I think you've got to take a 6 months leave if you try it on your face...

And someone has got to do something about asking acell to use it on facial scars. I mean, it can turn positive results for that guy growing hair back, but if noone uses it for acne scars as a clinical application, it still would be useless to us.

oh yea, and heck juvista is not gonna work and its too long...

^ why do you think that Juvista won't work?

and yeah i agree that acell must be tried on a facial scar also

After seeing those updated improvment i would definately be happy with that kind of result even if that was the best that could be achieved. Maybe its low standards after seeing so many poor scar treatments but that result is amazing to me. Holdontohope I think pigmentation is very important and I sure wouldn't want to be applying makeup but once again I don't see why acell would pick and choose what parts of your skin it would regenerate so I can't see it being a problem anyway. I can't wait for more doctors to start playing around with acell.

After seeing those updated improvment i would definately be happy with that kind of result even if that was the best that could be achieved. Maybe its low standards after seeing so many poor scar treatments but that result is amazing to me. Holdontohope I think pigmentation is very important and I sure wouldn't want to be applying makeup but once again I don't see why acell would pick and choose what parts of your skin it would regenerate so I can't see it being a problem anyway. I can't wait for more doctors to start playing around with acell.

It is all about time. Over the weeks there should regeneration, to skin tissue. Hopefully the skin cells and tissue cells will have a free reign and be allowed to nit freely across the 3d ecm material that is not denatured.

After seeing those updated improvment i would definately be happy with that kind of result even if that was the best that could be achieved. Maybe its low standards after seeing so many poor scar treatments but that result is amazing to me. Holdontohope I think pigmentation is very important and I sure wouldn't want to be applying makeup but once again I don't see why acell would pick and choose what parts of your skin it would regenerate so I can't see it being a problem anyway. I can't wait for more doctors to start playing around with acell.

Microskin is not makeup. It is simply a spray containing skin cells that would add an extremely thin layer over your already existing multiple layers of dead skin cells that you have on your face and body right now. I'd prefer not to ever have to use it, but it's pretty cool that this option is out there for both men and women to use.

Melanocytes are the cells in skin that are responsible for pigmentation. Let's hope those develop after the wound is healed.

These are existing charitable foundations which are dedicated to research on skin regeneration and wound healing. Pretty cool. No charitable foundation dedicated to this cause exists in the United States...yet. : )

http://www.blondmcindoe.com/index.shtm

http://www.thehealingfoundation.org/

http://www.raft.ac.uk/news/2008-07-17.html

New Acell photos: http://www.drrobertjones.com/2008/11/new-photo.html

This is a good start i must say. It looks that the scar is healing nicely.

I think you've got to take a 6 months leave if you try it on your face...

Hypothetically speaking if this stuff works, and the downtime turns out to be long ...my plan is to spot treat around 3 or 4 scars at a time ...you know just enough spots where yeah the healing parts are noticeable but not enough to keep you "down" for a matter of time.

I'm sorry, but why exactly would you need 6 months downtime to heal? I can understand it taking 6 months for everything to fully regenerate, but things would have to continue to progress in the meantime. I'm thinking a few weeks downtime is more like it.

I'm sorry, but why exactly would you need 6 months downtime to heal? I can understand it taking 6 months for everything to fully regenerate, but things would have to continue to progress in the meantime. I'm thinking a few weeks downtime is more like it.

Good point...we are just speaking in hypotheticals. The fact is we do not know how long it would take. My guess it would take longer than a regular wound heal because stuff has to actively migrate to the site and then grow ...it just doesn't accumulate out of thin air. The question of downtime is because we are assuming the outer most layer, the layer that is visible will be the last to regenerate/become repigmented so it could be red and raw looking for a while.

http://www.drrobertjones.com/acell.html

Check the new update, really really very impressive. Hair looks to be growing back.

Am i the only one who thinks the hair regrowth just looks like hair surrounding the wound which was shaved before hand?

Am i the only one who thinks the hair regrowth just looks like hair surrounding the wound which was shaved before hand?

No, Lamarr, you aren't the only one. Hair is absolutely NOT growing at the wound edges. It's totally irresponsible (bordering on unethical) of Dr. Jones to write in his blog that he surmises that HAIR is growing at the wound edges when they are clearly mature hairs that were there before the experiment. They are too long to be coming from new follicles. The wound is contracting, which is why everything is being brought closer together. The likelihood that Acell can regrow hair is very low. There is no proof - only photos on their website of animals regrowing fur over healed wounds. Animals have been shown to regrow fur over a healed wound site without the help of ANY regenerative materials like Acell. Humans....not so much.

My advice would be to chill out and stop speculating. We'll know when it's fully healed. Even then, we really won't know what the average aesthetic results will be until Acell is tried several more times and we get to see a variety of outcomes.

I don't know, but to me, I definitely see hairs growing in that pink area which seems like part of the wound. Of course, I have grown hairs out of areas of scars before, so it can happen.

I'm worried that this thing looks too much like any wound would heal, the pink puffy edge is just coming in and is like a guaranteed scar I think.