57 minutes ago, alyssum said:Yeah but it doesn't negate what Longaker said about the wound getting stitched up after. I doubt the writer would just make that up..? I also doubt the clinic will let you leave with an open wound. A bandage would not prevent infection. They mentioned they plan to test verteporfin on cleft lip patients. I don't know for sure but I imagine the patients will be stitched up rather than sent home with a gash on their face.
They won't be sent home at all until they're healed I think, cleft lip patients, cause this is a trial, so they will extensively study the result and healing process for sure.
9 hours ago, NagarNikku_ said:
Lmaoo. Its weird how emer knows that verteporfin will never be approved or helpful. Itd be better if he said there is no proof or research done with verteporfin and humans, but hegoes straight to a definitive no. Hedrather push shitty treatments that are overpriced.
@NagarNikku_The response reads like a bot wrote it.
Dr Chen who is doing the verteporfin trials believes that verteporfin will be available for use in scars in 2-5 years.
https://mobile.twitter.com/kellenchen_/status/1452741411057455104
10 hours ago, Tom_Mason said:@NagarNikku_The response reads like a bot wrote it.
Dr Chen who is doing the verteporfin trials believes that verteporfin will be available for use in scars in 2-5 years.
https://mobile.twitter.com/kellenchen_/status/1452741411057455104
I think Chen was referring to FAKI, not Verteporfin. Verteporfin could be sooner since its already approved.
13 hours ago, gueste said:
Cool stuff.
I guess it seems like.. the verteporfin research spawned different teams..
One with FAKI. In which he says the onlything not fully regenerating is the hair. (Which most of us dont give a **** about).
And the other team is working with verteporfin.. if there evenis such a group, havent heard any wordfrom that side since their originalresearch was published.
From a profit perspective, verteporfin doesnt make much sense to pursue, Im not sure how patentable the use case will beand is damn expensive.
FAKI on the other hand, can become a proprietary device, and potentially cheaper to make. At the cost of the consumers wasted life.
Its hard to ignore the words of a Stanford post doc student, when he says his device completely eliminates scarring. Red flags go off, but its hard to pin point a motive, other than him just hyping up his research.
7 hours ago, Scars4Life said:Cool stuff.
I guess it seems like.. the verteporfin research spawned different teams..
One with FAKI. In which he says the onlything not fully regenerating is the hair. (Which most of us dont give a **** about).
And the other team is working with verteporfin.. if there evenis such a group, havent heard any wordfrom that side since their originalresearch was published.
From a profit perspective, verteporfin doesnt make much sense to pursue, Im not sure how patentable the use case will beand is damn expensive.
FAKI on the other hand, can become a proprietary device, and potentially cheaper to make. At the cost of the consumers wasted life.
Its hard to ignore the words of a Stanford post doc student, when he says his device completely eliminates scarring. Red flags go off, but its hard to pin point a motive, other than him just hyping up his research.
I personally care to have regenerated hair follicles as i lost eyelashes due to my eye issues ( inflammation etc ) but this is incredible news none the less , the future is getting brighter
absolutely irrelevant today,butfunny still. Remember that PolarityTE hype back in 2017? They are still alive lol
On 12/20/2021 at 2:34 AM, gueste said:
I don't understand that very well. or Google translates incorrectly. so we can't get rid of the scars we have with verteporfin? Do they need to do more research to find out?
It just means that they need to cut out the scar before using the drug -- that is, the drug won't dissolve an existing scar if injected into the scar, but if you create a new wound by cutting out the scar, it will heal scarlessly.
BTW, that email is not about Verteporfin but a more experimental drug that is a FAKI inhibitor, preventing the body from sensing tension. The end result is similar and the drug could potentially work in combination with Verteporfin for even better results.
We haven't had any updates on Verteporfin specifically but they should be coming soon.
It's a little confusing because both projects are from Stanford and have many of the same scientists working on scarless healing, but they're two different projects. One involves Verteporfin, and another involves a FAKI inhibitor. The email is talking about the latter.
On 1/1/2022 at 10:44 AM, k95 said:It just means that they need to cut out the scar before using the drug -- that is, the drug won't dissolve an existing scar if injected into the scar, but if you create a new wound by cutting out the scar, it will heal scarlessly.
BTW, that email is not about Verteporfin but a more experimental drug that is a FAKI inhibitor, preventing the body from sensing tension. The end result is similar and the drug could potentially work in combination with Verteporfin for even better results.
We haven't had any updates on Verteporfin specifically but they should be coming soon.
It's a little confusing because both projects are from Stanford and have many of the same scientists working on scarless healing, but they're two different projects. One involves Verteporfin, and another involves a FAKI inhibitor. The email is talking about the latter.
understandably. Thank you. but when verteporfin publishes new data
On 12/28/2021 at 12:33 AM, Scars4Life said:I guess it seems like.. the verteporfin research spawned different teams..
I've been looking into this and the faki hydrogel has been in development since 2017. At least, they have had funds since 2017. There are patents filed since 2019 about using this method. They know what stops scarring, and wanted to repurpose a drug(Verteporfin) so it would be easily accessible. The FAKI research has been before the verteporfin research.
The link to the FAKI project summary: https://doctrc.org/wp-content/uploads/2021/08/Gurtner.pdf
Hoping that we can see some results with verteporfin. Just have to find a surgeon that will be willing to try it since most surgeons are only going to wait for clinical studies to be published which is reasonable.
I have a science background nothing to do with this area but from what I can tell the current trial from Mr Chen is just an advancement on from theVerteporfin drug. By means of a way of efficiently applying it and making a feasible economic path onwards. So therefore if the main base of the drug isVerteporfin and that is already FDA approved then the trials change from having to prove it is safe to proving it is effective. This dramatically shortens the time needed for approval, I was wondering if anyone has contact with a member of the study and can ask them how close they are to there initial plan of starting the human trial of the product by the third quarter of 2022. From this point if all good you should expect approximately 2 years until full approval. However means of production would not be granted till approval, depending on the legal patents, it may take 1-2 years to reach full scale production and if they manage to get full hair regrowth then you are looking at billions added to the potential market. Therefore the chance of months after approval the scale of production being able to cope with demand is near impossible therefore probably encouraging huge prices in the short run or making it near impossible for the cosmetic user to gain access until production is increased.
This mayalso be interesting. Trying to get more info
Dr Fiona Woods is working on a scarless healing cream:PXS-6302
First human trials for scar-less wound healing cream(uwa.edu.au)
I was wondering if anyone has any information on the mouse, pig or human verteporfin trials. As was wondering what kinda dosages are expected and how if they say to inject into wound edges is that still applicable to large scale burns.