Holdontohope it was a webcast, but I'm sure the website publishes most of its talks on a creative commons eventually. I did record it, and can give you a rough transcript of that piece if you want.

Holdontohope it was a webcast, but I'm sure the website publishes most of its talks on a creative commons eventually. I did record it, and can give you a rough transcript of that piece if you want.

Kirk: I'd love a transcript if it wouldn't be too much trouble. Thanks.

Did you guys even read my post? -_-

I addressed the subcutaneous thing already.

Also, I remember someone saying that the Adipose or fatty tissue of deep wounds would be unable to regenerate, but he says he fully believes it will. He said in clinical trials with animals, damage to the bone was fully regenerated all the way through, in some cases with just one application. He then joked that animals heal way better than humans though.

Adipose tissue is the main composition of the subcutaneous layer.

I also implied their confidence in follicle regeneration through this statement.

In the case of doctor Umar, he said that one of his guys was supposed to meet with him last week Friday? I think? But there was a scheduling conflict. He said last he heard Dr. Umar was awaiting the pictures to send to Acell. He also stated that hair regrowth also takes longer than simple skin regrowth as once the skin is in place it takes a few more weeks for follicles and stuff to regenerate.

Now as far as will it regenerate this, will it regenerate that. Mike manning said this. "It will regenerate whatever your DNA says should be there." Simple as that. Of course that's within reason, you can't cut off your leg and expect to rub some powder in it to grow back (at least not in the current incarnation of Acell lol). I mean think about this guys, what is this thing supposedly doing..?

It's supposed to:

-Inhibit the inflammation that causes scarring

-Attract natural healing elements from within ones own body

Now, say it really does do that. Then it should regenerate what was there, no? If it does and acts as it says it does, I don't see any reason it wouldn't regenerate or just "leave out" some bodily structure. Remember, this allegedly isn't scar tissue it's supposed to grow here...it's new tissue. Big difference between the two. As I said, in the veterinary world, they have had 100% regrowth of everything from bone to fur. And you know what you need for fur....? Follicles

I too have VERY extensive scarring. And even with the advent of this hope Acell brings, I too wonder HOW I would apply it =/ A DEEP dermabrasion works in theory, but one would have to go deep enough to destroy all the scar tissue. I am considering trying a test spot on my shoulder or chest, as Acell I think will best benefit my body scarring.

I don't think you mentioned this Zhou, but do you know if the scar treated was on the face? I know several people were enquiring about that. Thanks.

Did you guys even read my post? -_-

 

I addressed the subcutaneous thing already.

 

Also, I remember someone saying that the Adipose or fatty tissue of deep wounds would be unable to regenerate, but he says he fully believes it will. He said in clinical trials with animals, damage to the bone was fully regenerated all the way through, in some cases with just one application. He then joked that animals heal way better than humans though.

 

Adipose tissue is the main composition of the subcutaneous layer.

 

I also implied their confidence in follicle regeneration through this statement.

 

In the case of doctor Umar, he said that one of his guys was supposed to meet with him last week Friday? I think? But there was a scheduling conflict. He said last he heard Dr. Umar was awaiting the pictures to send to Acell. He also stated that hair regrowth also takes longer than simple skin regrowth as once the skin is in place it takes a few more weeks for follicles and stuff to regenerate.

 

Now as far as will it regenerate this, will it regenerate that. Mike manning said this. "It will regenerate whatever your DNA says should be there." Simple as that. Of course that's within reason, you can't cut off your leg and expect to rub some powder in it to grow back (at least not in the current incarnation of Acell lol). I mean think about this guys, what is this thing supposedly doing..?

 

It's supposed to:

-Inhibit the inflammation that causes scarring

-Attract natural healing elements from within ones own body

 

Now, say it really does do that. Then it should regenerate what was there, no? If it does and acts as it says it does, I don't see any reason it wouldn't regenerate or just "leave out" some bodily structure. Remember, this allegedly isn't scar tissue it's supposed to grow here...it's new tissue. Big difference between the two. As I said, in the veterinary world, they have had 100% regrowth of everything from bone to fur. And you know what you need for fur....? Follicles

 

I too have VERY extensive scarring. And even with the advent of this hope Acell brings, I too wonder HOW I would apply it =/ A DEEP dermabrasion works in theory, but one would have to go deep enough to destroy all the scar tissue. I am considering trying a test spot on my shoulder or chest, as Acell I think will best benefit my body scarring.

 

Zhou I've read your posts, in my last posts I was just using someone elses information to reaffirm what I know (I know it regenerates every tissue), and what you know, and others know.

Holdontohope the talk was about 30minutes... What I will do is put a transcript of that part about the regeneration of easy tissue, like skin, bladder when I get round to it soon.

Thanks for the infro zhou.

And yeah, same as Datura's question. What is the location of the scar treated?

I don't think you mentioned this Zhou, but do you know if the scar treated was on the face? I know several people were enquiring about that. Thanks.

I actually don't know =( I didn't think to ask.

Here is something I was wondering though...

Picture this:

You get a small excision, and treat it with Acell (whether it be the powder or sheet). Compress it with a regular bandage etc.,. Now, wouldn't you theoretically be able to do that without sutures? No matter the area? I mean if Acell "inhibits" scar tissue formation, shouldn't this be a feasible method? I've gotten some pretty big cuts and scrapes before that have healed without stitching (granted many were not full surface though)... So, why can't one simply apply Acell and compress it with a bandage, and let it seal back up on it's own? I mean you would just need to make sure you wouldn't bleed out right? lol Sure it might take a little while longer to heal, but shouldn't it bridge the gap on it's own, since your DNA "says" there should be skin there?

Picture this:

 

You get a small excision, and treat it with Acell (whether it be the powder or sheet). Compress it with a regular bandage etc.,. Now, wouldn't you theoretically be able to do that without sutures? No matter the area?

I don't see why not. Doctors who utilize dermal grafting to repair scars often just use bandages to cover up the healing area.

Isn't Acell first formed in liquid form before turned into sheets? In which case, maybe we would benefit slowly by liquid injections?

Anyway I found an interesting article to cheer people up!

Scientists regrow damaged tissue

http://thetartan.org/2008/10/13/scitech/stemcells

saw this article the other day.

http://www.marketwatch.com/news/story/intr...D&dist=hppr

i'm wondering if this is legit or if this is just some typical fat transfer and another ploy by some decietful doctor to take our hard earned money.now we're getting stem cell creams and lotions.damn,the cosmetic surgery community can be so corrupt.

Interesting articles guys.. Thanks for sharing

and yeah, the Acell sounds promising..

Does anyone know when will we be able to use the Acell?

Hey guys, I found this on some hairloss forum. On Friday, Oct. 31st, Acell was officially tested on an excised strip scar from a hair transplant procedure. (In case you don't know - Strip scars occur when a strip of full-thickness skin dense with hair is removed from the back of the scalp. The strip is then dissected to painstakingly remove the follicles, which are then individually implanted into the bald areas of the head. The procedure leaves a linear scar on the back of the head that often stretches and widens over time, leaving a wide, hairless scar.)

Here's the link to pics right before a portion of the scar was excised, and immediately after, as a big, gaping wound, covered in Acell powder and two Acell sheets:

http://www.drrobertjones.com/acell.html

KEEP IN MIND: The progression of photos are posted from bottom to top, not top to bottom (which would have made more sense.) This procedure was performed TWO DAYS AGO, and the results will not be posted for probably a month. The wound is in the very beginning stages of healing.

Anyways, it's exciting to see this. Ideally, I wish they would reapply Acell with as many layers as it takes until it's healed completely. I also wish they were applying Low Level Laser Therapy (LLLT) to the wound, as it's been proven to be a great adjunct therapy to Acell as it accelerates healing and dramatically decreases scar formation.

I spoke with Mike Manning again from Acell and he mentioned that they were also testing Acell on FUE donor sites. The FUE procedure stands for Follicular Unit Extraction, where follicular units of hair are extracted from the back of the head and implanted on bald areas of the scalp. The units are extracted with tiny punches from .6mm - 1mm in diameter, leaving little holes in the back of the scalp. Sometimes they are stitched closed if they're closer to 1mm in size or bigger. Mike said the doc (I don't know who the doc is) was filling each hole with Acell powder. The only problem with this is that Acell is broken down very quickly, and it might disrupt the healing process to try and apply more powder to the very tiny healing wound. I suggested that instead of using powder, they tightly roll a sheet of Acell, creating a little "stick" that can be pushed into each hole. This way, and as Acell dissolves and is converted into tissue, it is met with yet another layer of Acell until the wound closes completely. I hope that makes sense. He said it was a great idea and promised he would talk to Acell engineers about how to do that.

How does this apply to us? Well, for acne scar sufferers with ice pick scars and/or tiny scarred pores, they could be punch-excised, and, instead of stitched closed or grafted with skin, the method mentioned above could be applied to this scenario.

Anyways, it's exciting to see some progress.

^ wow that's really interesting !! thanks alot holdontohope.

What i understood is that this patient already had a hair transplantation before, which obviously leaves a scar at the back. And now he is trying to treat the scar (or trying to get more hair at the back to use it). You can see from the first pic (the first one from the bottom) that there is no hair in that area, which means that he underwent the prodcedure before. Anyway, we are not interested in the in hair transplantation procedure here. The scar results is what we want

Thanks again holdontohope !

That's great that Mike Manning is so receptive to hearing outside ideas and was willing to share this with the engineers. I know a lot of times it can be frustrating just to get someone to hear your ideas. Perhaps, I'll give him a call myself and see if I can be included in an upcoming trial. I've heard a lot about acell being used in the area of hair transplants and people seem to think it's promising, but we all know seeing is believing, so I'll be keeping up with this guy's progress to see how this scar heals.

That is really exciting... I do wish I could see what the original scar looked like a little bit better.

The following link has NOTHING to do with the little Acell test shown above as performed by Hair Transplant doctor, Dr. Jones. The following link is to the government website showing that the clinical trial sponsored by the United States Army Institute of Surgical Research. I have no idea what it means. I have no idea, but I will call Acell about it, and post later.

http://clinicaltrials.gov/ct2/show/NCT00352729

I checked the website holdontohope. But i couldn't understand everything.

Can you help me please. Does it mean that it has already been tested or what?

Okay, now I'm confused:

 

http://clinicaltrials.gov/ct2/show/NCT00352729

 

WTF??? I'm gonna call Acell about this.

Please do, as I am confused as well...

I edited my previous post with the clinical trials link on the previous page regarding this link: http://clinicaltrials.gov/ct2/show/NCT00352729

I'll go ahead and repeat myself right here:

Please take note that the url address above that links to the study using Acell on skin graft donor sites for burns was funded by the United States Army Institute of Surgical Research and has NOTHING TO DO with the link I posted yesterday afternoon concerning the Acell test performed by Dr. Jones. That is still going on, but we, of course don't have the results, as the wound is only 3 days old.

I'll call Acell later and inquire about this "terminated" study.

Regarding this link: http://clinicaltrials.gov/ct2/show/NCT00352729

Just spoke with Mike Manning. He had no knowledge of the study being terminated. He was actually quite surprised, but said it could mean a number of things and will be calling some other Acell contacts who know more about this study to find out. He took my number and said he'd call me back by tomorrow - maybe sooner - as the guy who *might* know what's going on won't be in til then.

Before we all freak out, this might mean absolutely nothing, as I just noticed that at the bottom of the page it says "Last Updated: January 8, 2008". So, if it means nothing, then I'm sorry for the false alarm. Regardless, Mike did say that he would be surprised if the study was terminated. He said something to the effect of "If this is true, then I'll be surprised as they said things were going so well with the initial Acell tests on skin graft donor sites that they'd begin testing it on actual burns..." Something like that. Anyways... I"ll keep ya updated. I still think it's exciting that Acell is being tested on the excised hair transplant scar.

Holdontohope here is a transcript of that bit,

Interviewer: Can you envision the end of common organ transplants in your lifetime?

SB: Yes I can. If were, if we learn how to extend this technology, right now we can do a pretty good job of forming normal simple tissues, urinary bladder skin tissues like that. Really the challenge we have right now is can we do this for whole organs, like liver, like kidneys, hearts and so forth.

please keep us updated holdontohope..

thu its kinda weird.. its their company and they don't know who's using it ..

I don't think that the clinical trial result is anything to worry about in terms of Acells effectiveness. The impression that I got was that Acell was perhaps not suited to those burns or that the method of delivery hadn't been perfected but certainly not a failure of the product itself. If failure were the case I don't think Acell would have put in all the effort in terms of court cases and the like and would have just cut their losses.

I agree with you, Tom. The truth is that we have no idea what that means. The exciting thing is that Acell is being tested on open wounds, and we're going to soon know just how effective it can be. This blog will be updated regularly on the guy's Acell/wound-healing progress: http://www.drrobertjones.com/acell.html

The only things that concern me is that sutures were used on the wound, and we know that wound tension of any kind can worsen scarring. Also, only a portion of the scar was excised (scar goes across entire back of head), so we have yet to see if any scar tissue is regenerated or if it's normal skin.

For now, we wait.