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[Sticky] Scarless Healing

 
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(@miro)

Posted : 08/22/2020 1:16 pm

I mean acne scars that are deeper then superficial, , they go deeper yes , and usually the volume loss includes fat loss.

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(@armanilko)

Posted : 08/22/2020 2:34 pm

1 hour ago, Miro said:

I mean acne scars that are deeper then superficial, , they go deeper yes , and usually the volume loss includes fat loss.

I didn't know acne scars could go that far. Maybe that's why they say they still need to work on some farm of acne scarring at elastagen, since it's deeper than the dermis? At least compared to stretch marks which are "only" in the dermis.

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(@rosinsky404)

Posted : 08/22/2020 3:12 pm

20 minutes ago, Armanilko said:

I didn't know acne scars could go that far. Maybe that's why they say they still need to work on some farm of acne scarring at elastagen, since it's deeper than the dermis? At least compared to stretch marks which are "only" in the dermis.

Thats why with acne scars you always hear about people trying to level the scars. You lift them up with subscision to get rid of where they are tethered beneath the skin. You can add filler so they stay lifted up while the subscision heals. You can fill in the icepickswith new skin using CROSS. RF therapy can tighten your skin up so the scars tighten too. Microneedling can help smooth the texture a bit.Then there is stuff like deep chemical peels and lasers to do a more thorough resurfacing. You resurface theskin and address textural problems as the last step for acne scar revision.

I think for when elastagen is first released for acne scarsit willbe most usefulas a last step for retexturing, when all the scars are level and at the surface. Maybe it will have its place as a filler,but I hope what well see is it usedas a topically appliedtreatmentto use after a strong laser or dermabrasion type of procedure- sort oflike recell but better.

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(@nikkigirl)

Posted : 08/22/2020 3:48 pm

Most of these if not all treatments are to just take your money....i know i spent 1000's of dollars on crap that didn't work.....funny...you get your money back if it doesn't work.If that was the case...nobody would be even claiming they could get your scars better!All snake and oil!

38 minutes ago, tortoiseshell9 said:

Thats why with acne scars you always hear about people trying to level the scars. You lift them up with subscision to get rid of where they are tethered beneath the skin. You can add filler so they stay lifted up while the subscision heals. You can fill in the icepickswith new skin using CROSS. RF therapy can tighten your skin up so the scars tighten too. Microneedling can help smooth the texture a bit.Then there is stuff like deep chemical peels and lasers to do a more thorough resurfacing. You resurface theskin and address textural problems as the last step for acne scar revision.

I think for when elastagen is first released for acne scarsit willbe most usefulas a last step for retexturing, when all the scars are level and at the surface. Maybe it will have its place as a filler,but I hope what well see is it usedas a topically appliedtreatmentto use after a strong laser or dermabrasion type of procedure- sort oflike recell but better.

By the way i had rounds of subcision and fillers....didn't do squat for me.

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(@rosinsky404)

Posted : 08/22/2020 4:22 pm

8 hours ago, nikkigirl said:

Most of these if not all treatments are to just take your money....i know i spent 1000's of dollars on crap that didn't work.....funny...you get your money back if it doesn't work.If that was the case...nobody would be even claiming they could get your scars better!All snake and oil!

By the way i had rounds of subcision and fillers....didn't do squat for me.

Im sorry to hear that subcision and fillers didnt work for you. Thats not to say they dont seriouslyhelp a lot of people. There is realistic hope in current technology.

Acne scar treatments are dependent on an individualsscars and healing ability. And there is an order youre supposed to do things in with treatments to get the most improvement possible at this time.

Elastagen wont be a miracle cure. It will just be a new treatment.I think it will help widespread scarring a lot more effectively if a patient already had resurfaced their scars as much as possible before treatment.

If we all got 60% improvement on our scars from elastagen that would be so cool!! I hope it works that way! But elastagen is still probablya long way away,and not everyone will be guaranteed thesame results just like the treatments we have available to us now.

But if you have severe scars and only ever try touse elastagen to treat them you will only see 60% total improvement. If you can improve your skin by 30 or 40%+ withother treatments before you get elastagen- you will end up with a much more thorough result cause youre starting out with less damage.

Thatsmy take anyway

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(@didikaxonim)

Posted : 08/23/2020 12:45 am

8 hours ago, tortoiseshell9 said:

Im sorry to hear that subcision and fillers didnt work for you. Thats not to say they dont seriouslyhelp a lot of people. There is realistic hope in current technology.

Acne scar treatments are dependent on an individualsscars and healing ability. And there is an order youre supposed to do things in with treatments to get the most improvement possible at this time.

Elastagen wont be a miracle cure. It will just be a new treatment.I think it will help widespread scarring a lot more effectively if a patient already had resurfaced their scars as much as possible before treatment.

If we all got 60% improvement on our scars from elastagen that would be so cool!! I hope it works that way! But elastagen is still probablya long way away,and not everyone will be guaranteed thesame results just like the treatments we have available to us now.

But if you have severe scars and only ever try touse elastagen to treat them you will only see 60% total improvement. If you can improve your skin by 30 or 40%+ withother treatments before you get elastagen- you will end up with a much more thorough result cause youre starting out with less damage.

Thatsmy take anyway

i read in a post.elastagen on average 80% would be good

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(@rosinsky404)

Posted : 08/23/2020 2:42 am

1 hour ago, Didikaxonim said:

i read in a post.elastagen on average 80% would be good

You know what- I really hope so :) 

We of course have to wait until the papers come out to see what improvement can look like and learn how it will work. And then we™ll have to wait a while for the elastagen to be made available to the public. 

That could take a long time so I™m going to live in the present until the technology comes out- get as much improvement as I can until the elastagen is perfected and released.

If I get good improvement now- I™ll have even better improvement when elastagen comes out so that™s what I™m focusing on :)

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(@miro)

Posted : 08/23/2020 4:17 am

Well dont wanna ruin all your dreams but :

https://www.businesswire.com/news/home/20180106005027/en/Elastagen-Feature-Breakthrough-Tissue-Repair-Aesthetic-Platform

 

the final study was supposed to be revealed on Q1 2018, and the site they refer to :

www.elastagen.com doesnt even work anymore

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(@voulzeyes)

Posted : 08/23/2020 4:40 am

23 minutes ago, Miro said:

Well dont wanna ruin all your dreams but :

https://www.businesswire.com/news/home/20180106005027/en/Elastagen-Feature-Breakthrough-Tissue-Repair-Aesthetic-Platform

 

the final study was supposed to be revealed on Q1 2018, and the site they refer to :

www.elastagen.com doesnt even work anymore

Elastagenns website had to shut down 2 years ago because of the allergan acquisition, we've known for a long time, lol. You can use the wayback machine though if you want to check it out. Also the final study was actually released... But only to private investors, which is why allergan bought them. The one coming at the end of the year or early 2021 will be public.

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(@miro)

Posted : 08/23/2020 4:46 am

3 minutes ago, voulzeyes said:

Elastagenns website had to shut down 2 years ago because of the allergan acquisition, we've known for a long time, lol. You can use the wayback machine though if you want to check it out. Also the final study was actually released... But only to private investors, which is why allergan bought them. The one coming at the end of the year or early 2021 will be public.

Oh ok, I guess i have to be thatbad guy here that keeps your expectations low :-), however from what i red on site its supposed to be some kind of filler that should regenerate scarred tissue , so they inject it into the scar or something, i really wonder how this possible could work.

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(@gantz)

Posted : 08/23/2020 4:52 am

 

32 minutes ago, Miro said:

Oh ok, I guess i have to be thatbad guy here that keeps your expectations low :-), however from what i red on site its supposed to be some kind of filler that should regenerate scarred tissue , so they inject it into the scar or something, i really wonder how this possible could work.

This tool is marketed as an intradermal implant. It fills the cavity of an atrophic scar.Another application is wound healing, and how tropoelastin works this wayis still unclear for me.

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(@gantz)

Posted : 08/23/2020 5:18 am

53 minutes ago, Miro said:

Well dont wanna ruin all your dreams but :

https://www.businesswire.com/news/home/20180106005027/en/Elastagen-Feature-Breakthrough-Tissue-Repair-Aesthetic-Platform

 

the final study was supposed to be revealed on Q1 2018, and the site they refer to :

www.elastagen.com doesnt even work anymore

I looked at the dermatology summit website and found no mention of elastagen. It is possible that this data was only for investors. By the way, in your newsletter there was the following text: "full study will be submitted for publication in Q1 2018". At this quarter, a month after the summit, elastagen was bought by allergan.

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(@armanilko)

Posted : 08/23/2020 6:08 am

1 hour ago, Miro said:

Oh ok, I guess i have to be thatbad guy here that keeps your expectations low :-), however from what i red on site its supposed to be some kind of filler that should regenerate scarred tissue , so they inject it into the scar or something, i really wonder how this possible could work.

Naaah you're not the bad guy he prob didn't mean that xDD

Also I think it was @lehran who mentioned that it should be seen as an implant more than a filler (although I guess you could call it both honestly, it's a liquid implant). So basically it solidifies into new skin that can grow hair and that can sweat once accepted by the surrounding tissue.

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(@lehran)

Posted : 08/23/2020 6:24 am

-Yeah it was pretty much for "investors eyes" only. Can't really blame them honestly, this is the kind of stuff you release to the public once you know how you'll properly administer it and stuff. And yes, it should be seen as an implant, as it "replaces" the atrophic zones where healthy skin tissue is lacking.

-Here's a link to the old elastagen website since people have been mentioning it: http://elastagen.com /" rel="external nofollow"> https://web.archive.org/web/20190423230745/http://elastagen.com

-Imo here's the most interesting part, that was from 2018: https://imgur.com/a/eAj0XJu

 

 

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(@rosinsky404)

Posted : 08/23/2020 2:04 pm

Im really stoked about the wound repair side of it too because i feel like if you have that down - you are able to retexture/repairskin in a whole new way.

You could get excisions to heal much better, more quickly andyou wouldnt have to worry about tension pulling on the wound as it heals. There might also be a way to get ablative laser or dermabrasion and then have elastagen applied on top so you pretty much grow a brand new synthetic skin. That could work well for surface/textural scars or even anti aging.

If big pharma company allergan bought it pretty much as soon as the investors were presented the data- its probably gonna be really good and easily profitablefor rolling scars and stretch marks. More applications will come later and it will be used off label eventually like botox and silikone 1000gets used off label all the time.

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(@gantz)

Posted : 08/23/2020 2:21 pm

16 minutes ago, tortoiseshell9 said:

There might also be a way to get ablative laser or dermabrasion and then have elastagen applied on top so you pretty much grow a brand new synthetic skin. That could work well for surface/textural scars or even anti aging.

 

No, you cant grow new syntheticskin. Patent of elastagen tells us only about injextion of tropoelastin whichstarts the process of elastogenesis.As a result, elastin fibers begin to form under the skin, which fill the space of the atrophic scar.Don't overestimate expectations

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(@lehran)

Posted : 08/23/2020 3:28 pm

1 hour ago, gantz said:

No, you cant grow new syntheticskin. Patent of elastagen tells us only about injextion of tropoelastin whichstarts the process of elastogenesis.As a result, elastin fibers begin to form under the skin, which fill the space of the atrophic scar.Don't overestimate expectations

Word. Their product has potential, but they're not yet at a point where they can just grow synthetic skin and blood vessels out of nowhere to just completely replace skin on any support. This is planned but it's not going to happen just like that (linking the audio clip):

 

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(@rosinsky404)

Posted : 08/23/2020 4:56 pm

I™m not gonna get my hopes up cause who knows when it™ll even be on the market. :)

@gantz This is helpful though, i didn™t get how it was supposed to work from beneath the surface of the skin. 

I™m really just excited to learn more about it. I can™t wait to find out if this will just be helpful for widespread rolling scars or if this can help individual pits.

I˜m very excited to hear about what it can do for wound repair because I think we™ll be able to do scar excisions a lot better when this technology comes out. 

@lehran thanks for the clip i™ll be sure to give it a listen

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(@yepitsmewee)

Posted : 08/23/2020 8:47 pm

On 8/17/2020 at 1:20 PM, Skin Pessimist said:

Micro coring only removes a small area though. Removing out a wide area of scarred tissue and promoting new healing is something I trust Elastagen more with. There are proof of concept videos showing elastagen sealing an open wound within a minute. If Elastagen works, it's success may depend on the delivery method. Without creating a new wound, Elastagen could be inserted into a rolling scar. That would reduce volume loss, but I doubt it would remove the existing scar tissue. Maybe the existing scar won't be noticeable so it won't matter. The most promising application of Elastagen would be removing the existing scar tissue, creating a new wound, and then applying Elastagen. I'm not sure that sort of process is ready yet.

Some posters disagree with me but I'll continue doubting micro coring unless it is shown to be practical for large scars. Micro coring only removes a narrow area of skin. It seems like something that would work best on ice pick scars. I doubt it will ever be a great option for wider scars, since it would require many sessions. For those scars, you'd probably be better off opting for subcision. Of course, none of us really know for sure. My entire post is full of speculation. We'll have to see

Where are these videos?

 

On 8/14/2020 at 2:28 AM, David4bay said:

Thanks for the update.

Will they have a single needle device to focus on scarred areas? From what I can tell, their smallest device has 10 needles in it. Microcoring is a great technology, but they don't have somethings for very fine scars.

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(@yepitsmewee)

Posted : 08/23/2020 9:08 pm

On 8/6/2020 at 1:16 AM, David4bay said:

For my scars, I'm a big supporter of the tech and logic behind microcoring. I did see a "microcoring-like" device being advertised on YouTube for use in treating wounds with transplanted microcores to speed up healing but until I get more info on the device(width, diameter and safety) to know if the excisions heal scarlessly I can't say it's the same kind of tool cytrellis is creating.

 

If all boxes check out I'll find a way to get it and test it out on a scar on my ankle, at least after 4 sessions 3 months apart in a year I'd be able to objectively say if it works and then go to work on all my scars.

 

Link

[Edited video out]

What link is this? It doesn't show

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(@yepitsmewee)

Posted : 08/23/2020 9:55 pm

On 8/10/2020 at 1:49 PM, skinregenerator said:

Sunogel is still going on

How do you know this?

 

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(@david4bay)

Posted : 08/24/2020 2:53 am

5 hours ago, yepitsmewee said:

What link is this? It doesn't show

It was formerly a public link for a device "Sperry bio", that was being used in the military to extract microcores and use hydrogels to implant them on full thickness wounds to regenerate the tissue, it was suggested that scarring can also be addressed with the device to remove scars but a few days after I contacted her for inquiry she took the video down, she might have not been allowed to talk on the device which is understandable as it also isn't commercialised yet. I have a scald scar on my periorial chin with full appendages so I'm more optimistic micro-coring would be the best fit to remove it piece by piece if it works as planned. I can and do live with the scar though, chicks love it in fact but if I can get rid of it, why not?

On the cellular level, needles that are small enough push cells away and activate a potential difference in cells that prompt healing without scar formation, micro-coring needles go a step further and extract the damaged tissue, and then in theory the surrounding skin closes in on these gaps and heals without scar formation. Clinical trials will reveal if it works on scars also, a person here said he contacted the company on that trial and they said it works great on scars but will need multiple sessions to remove as the volume of tissue removed could range from 5% to 10%(or more given the patent description) of the area of skin treated. The device works well for wrinkles as the results are quick to assess so it is being marketed as an anti-wrinkle device.

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(@gantz)

Posted : 08/24/2020 7:42 am

4 hours ago, David4bay said:

It was formerly a public link for a device "Sperry bio", that was being used in the military to extract microcores and use hydrogels to implant them on full thickness wounds to regenerate the tissue, it was suggested that scarring can also be addressed with the device to remove scars but a few days after I contacted her for inquiry she took the video down, she might have not been allowed to talk on the device which is understandable as it also isn't commercialised yet. I have a scald scar on my periorial chin with full appendages so I'm more optimistic micro-coring would be the best fit to remove it piece by piece if it works as planned. I can and do live with the scar though, chicks love it in fact but if I can get rid of it, why not?

On the cellular level, needles that are small enough push cells away and activate a potential difference in cells that prompt healing without scar formation, micro-coring needles go a step further and extract the damaged tissue, and then in theory the surrounding skin closes in on these gaps and heals without scar formation. Clinical trials will reveal if it works on scars also, a person here said he contacted the company on that trial and they said it works great on scars but will need multiple sessions to remove as the volume of tissue removed could range from 5% to 10%(or more given the patent description) of the area of skin treated. The device works well for wrinkles as the results are quick to assess so it is being marketed as an anti-wrinkle device.

Not surprising, because a facelift is one of the most demanded procedures.

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(@didikaxonim)

Posted : 08/24/2020 2:04 pm

11 hours ago, David4bay said:

It was formerly a public link for a device "Sperry bio", that was being used in the military to extract microcores and use hydrogels to implant them on full thickness wounds to regenerate the tissue, it was suggested that scarring can also be addressed with the device to remove scars but a few days after I contacted her for inquiry she took the video down, she might have not been allowed to talk on the device which is understandable as it also isn't commercialised yet. I have a scald scar on my periorial chin with full appendages so I'm more optimistic micro-coring would be the best fit to remove it piece by piece if it works as planned. I can and do live with the scar though, chicks love it in fact but if I can get rid of it, why not?

On the cellular level, needles that are small enough push cells away and activate a potential difference in cells that prompt healing without scar formation, micro-coring needles go a step further and extract the damaged tissue, and then in theory the surrounding skin closes in on these gaps and heals without scar formation. Clinical trials will reveal if it works on scars also, a person here said he contacted the company on that trial and they said it works great on scars but will need multiple sessions to remove as the volume of tissue removed could range from 5% to 10%(or more given the patent description) of the area of skin treated. The device works well for wrinkles as the results are quick to assess so it is being marketed as an anti-wrinkle device.

who were you associated with and when did you say it?

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(@david4bay)

Posted : 08/24/2020 3:30 pm

1 hour ago, Didikaxonim said:

who were you associated with and when did you say it?

Sorry I don't understand your question. I am talking about devices like Cytrellis clinical trial micro-excision device, and how I contacted a person that has worked on a similar type of technology the "Sperry Bio" system/device on YouTube, the lady I contacted took down the video of the device presentation and did not respond as the device is still under clinical trial and is subject to NDAs about the technology before commercialising. Does that answer your question?

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