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1 hour ago, damnBOY said:it needs 4-6 treatments, if you do the math , first treatment 25% scar coverage this means you remove 25% of the scar you wait 3 monthes you remove other 25% of the scar you wait 3 monthes another 25% after 4 treatments you will have remove 100% but lets say the last treatments the healthy skin is more than scar and you cant see were is the scar to be sure that you will have remove 100% of the scar you do more two treatments , in total you have removed 150% of the affected area.... the studies says you can remove up to 40% without scarring but lets say you want to 100% safe and you go down to 25% you will need 1-1,5 year to remove every scar from your body. the study says Thirty-two 1 — 1-inch sites per flank received either 20 or 40 percent treatment coverage. Photographs were taken and punch biopsies were performed at days 0, 7, 28, 56, and 84. Biopsy specimens were evaluated for histology and collagen content.
RESULTS:
All treatment sites healed quickly, with no evidence of scarring or infection. Coring sites were easily identified and contained increased fibroblast activity and newly synthesized collagen. At 1 month, the papillary dermis and epidermis of the coring sites were up to 196 percent thicker compared with controls (p < 0.001). The coring sites had enhanced undulating rete ridges-consistent with regeneration. At 3 months, a pronounced increase in collagen fibers and newly organized and augmented elastic fibers was seen. Enzyme-linked immunosorbent assay confirmed an 89 percent increase in collagen content in these coring sites (p < 0.001).
CONCLUSIONS:
This novel approach to skin rejuvenation was found to effectively induce the microscopic and biological endpoints of skin rejuvenation. This may provide a new modality for the safe and cost-effective treatment of age-related rhytides, skin laxity, photodamage,
in fact skin appendages can grow in healthy skin does anybody here has so big scars like burn scars with skin grafts and artificial skin I don't know how effective microcoring will be in these situations where affected areas are with artificial skin and skin grafts but for common acne scars , surgical scars , small scars , striae distancae of course it will but in these situation skin appendages are not a big deal you have most of the appendages , sweat glands are going down to hypodermis and the hair root also going down to hypodermis
How's SkinTE working out?
16 hours ago, MyBeautifulScars said:It will take 100000 + treatments to remove all that scar tissue.If you have the funds and time, you should definitely try it. If you ask me, it's not worth it.
Nope. It removes0.6mm per microcore. My scar is 1cm wide. You can do the math on that and yes I got the money to pay so why not? I dont expect perfect like some these folk so for me its a no brainier. I want as much fibrotic tissue gone as possible, thats my only goal. I think you will be surprised you know how much it could help if you scars were at least broken down in terms of appearance x
20 hours ago, PTAA said:How do you know there will be no appendages?
Because there is no appendages in fibrotic scar tissue so how micro coringout there scar wil bring back all the glands? Unless the individual still has them within the scar tissue which is possible then how will they magically reappear? Depends on level of damage like dammboy said.
1 hour ago, nikki_gargin said:Nope. It removes0.6mm per microcore. My scar is 1cm wide. You can do the math on that and yes I got the money to pay so why not? I dont expect perfect like some these folk so for me its a no brainier. I want as much fibrotic tissue gone as possible, thats my only goal. I think you will be surprised you know how much it could help if you scars were at least broken down in terms of appearance x
Because there is no appendages in fibrotic scar tissue so how micro coringout there scar wil bring back all the glands? Unless the individual still has them within the scar tissue which is possible then how will they magically reappear? Depends on level of damage like dammboy said.
appendages can grow back in a healthy skin that's why sometimes lasers and microneedling trigger hair follicle formation
People may find this interesting. Porcine study. If you look closely at the orange freckles you can see they have become wider vs the control. Looking like the skin has stretched also? This looks very good.
Fig. 1. Treatment sites preoperatively (left), postoperatively (second from the left), and 1 week (second from right) and 8 weeks (right) after a 25-gauge needle group at 40 percent coverage: solid needles (above) and coring needles (below).
3 minutes ago, nikki_gargin said:People may find this interesting. Porcine study. If you look closely at the orange freckles you can see they have become wider vs the control. Looking like the skin has stretched also? This looks very good.
What is this? Can you post a link please?
3 minutes ago, PTAA said:What is this? Can you post a link please?
3 minutes ago, PTAA said:What is this? Can you post a link please?
This skin contracts, heals and releases. You can see by the dots there pull inwards and then relax
8 minutes ago, nikki_gargin said:This skin contracts, heals and releases. You can see by the dots there pull inwards and then relax
This makes sense considering tissue expansion has been thoroughly proven. This means the tissue will come back as the skin stretches. Amazing! I think this might be what we've waited for. Excision without scarring!
50 minutes ago, PTAA said:This makes sense considering tissue expansion has been thoroughly proven. This means the tissue will come back as the skin stretches. Amazing! I think this might be what we've waited for. Excision without scarring!
not exactly . skin tightening happens only if you close the holes in first place usually with elastic membrane if you don't close the holes then skin tightening will not happen basically it will but at very small extent
1 hour ago, nikki_gargin said:This skin contracts, heals and releases. You can see by the dots there pull inwards and then relax
the skin contracts because of myofibroblast activation microcoring doesn't trigger myofibroblast activation and skin doesn't contracts if you see the before and after the skin didn't tight at all... look at the patent they said that microcoring will be usefull to release scar contraction
2 hours ago, nikki_gargin said:Do you have references or linkto your micro coring and Cytrellis quotes please?
40 minutes ago, damnBOY said:not exactly . skin tightening happens only if you close the holes in first place usually with elastic membrane if you don't close the holes then skin tightening will not happen basically it will but at very small extent
the skin contracts because of myofibroblast activation microcoring doesn't trigger myofibroblast activation and skin doesn't contracts if you see the before and after the skin didn't tight at all... look at the patent they said that microcoring will be usefull to release scar contraction
I mean wound contracture for healing, not scar contracture. You can clearly see the pull but only during the healing in the pics. Then it is relaxed again after 8 weeks. All wounds contract during closure. Even the black dots have been stretched, you can see.
the skin tightening is through contraction in wrinkles the wounds are small enough to pull together and close, scarless.but there is net lose in actual skin. Because the skin is so elastic however its not a problem. And improved collegen and the wound site. because as you know it is for removal of excess or unwanted skin. Or no one would loose any skin from the procedure.
Thanks for resources.
19 hours ago, damnBOY said:not exactly ¦. skin tightening happens only if you close the holes in first place ¦ usually with elastic membrane if you don't close the holes then skin tightening will not happen basically it will but at very small extent
the skin contracts because of myofibroblast activation microcoring doesn't trigger myofibroblast activation and skin doesn't contracts if you see the before and after the skin didn't tight at all... look at the patent they said that microcoring will be usefull to release scar contraction
Wouldn't it be preferable if there is skin tightening? If the excised tube is in the middle of a valley, then the regenerated tissue will still be too low in depth. I would want the wounds to tighten and close so that eventually the deepened areas are shrunk and removed. I've attached an illustration of what I'm saying.
23 minutes ago, PTAA said:Wouldn't it be preferable if there is skin tightening? If the excised tube is in the middle of a valley, then the regenerated tissue will still be too low in depth. I would want the wounds to tighten and close so that eventually the deepened areas are shrunk and removed. I've attached an illustration of what I'm saying.
It would take multiple treatments. and will likely never be perfect again, but you can get the dip to be almost unnoticeable in principle going by your illustration, I see what you mean. Honestly some people here are wrong in how this works. it deletes the skin, doesn't regenerate the skin. In the link below is Cytrellis publication that says in the anti ageing pic 5% skin removed. If there was no contraction and wound closure it would not tighten the skin at all. see for yourself and decide for yourself.
there is also a stretch mark pic, you can see again it has deleted some of it, not regenerated some of it. Also proof in the fact that the down time is 3 days. our bodies aren't regenerating shit in 3 days! lol
https://attendais.com/wp-content/uploads/2019/05/CytrellisBiosystems.pdf
Hello, I would like to thank everyone for the contributions you bring to this important forum. Here I was able to learn and learn many things.I would like to ask this if someone can answer me: I have a round, white and atrophic burn scar on my upper lip that borders on the skin above my lip. I have no skin grafts. Can Microcoring help me eliminate this scar completely? Is it also suitable for burn scars and lips? 1 hour ago, 0009774 said:Hello, I would like to thank everyone for the contributions you bring to this important forum. Here I was able to learn and learn many things. I would like to ask this if someone can answer me: I have a round, white and atrophic burn scar on my upper lip that borders on the skin above my lip. I have no skin grafts. Can Microcoring help me eliminate this scar completely? Is it also suitable for burn scars and lips?
Is there a gap between your lip border and the scar? How wide is the scar? Have you spoke to a plastic surgeon about scar revision? Im sure that could be improved with a z Plasty or something? Micro coring might be better after another intervention esp as its atrophic.
I have a surgical scar left over from excision of a burn scar. If the skin is thin in the scar it may not contract as it should with micro core? We wouldnt know that though but I would suggest you prep the area to get the best result in the future, by making the most of technology now.
19 minutes ago, hopfullady said:I cant wait to see how concentrated the procedure can be. I hope we are able to use it in a precise fashion to target mostly scar tissue. Has anyone seen what the tool looks like for Cytrellis ? I see Recros medica has images of their devices posted.
They do say about more than one tool so I reckon theyre using it in the scar trial.
14 hours ago, nikki_gargin said:Is there a gap between your lip border and the scar? How wide is the scar? Have you spoke to a plastic surgeon about scar revision? Im sure that could be improved with a z Plasty or something? Micro coring might be better after another intervention esp as its atrophic.
I have a surgical scar left over from excision of a burn scar. If the skin is thin in the scar it may not contract as it should with micro core? We wouldnt know that though but I would suggest you prep the area to get the best result in the future, by making the most of technology now.
Thanks for the reply Nikki. There is no gap between the lip edge and the scar. The scar is white, surgical inside the lip and white and sunken outside for oncological therapy by liquid nitrogen. It is 8 mm long and 4 mm wide. I heard several plastic surgeons, nothing can be done. I would hope that microcoring can eliminate it with various small removals. 1 hour ago, 0009774 said:Thanks for the reply Nikki. There is no gap between the lip edge and the scar. The scar is white, surgical inside the lip and white and sunken outside for oncological therapy by liquid nitrogen. It is 8 mm long and 4 mm wide. I heard several plastic surgeons, nothing can be done. I would hope that microcoring can eliminate it with various small removals.
Maybe they believe they will disfigure your lips if they try? Well fingers crossed for you in the future x
1 hour ago, 0009774 said:Thanks for the reply Nikki. There is no gap between the lip edge and the scar. The scar is white, surgical inside the lip and white and sunken outside for oncological therapy by liquid nitrogen. It is 8 mm long and 4 mm wide. I heard several plastic surgeons, nothing can be done. I would hope that microcoring can eliminate it with various small removals.
Maybe they believe they will disfigure your lips if they try? Well fingers crossed for you in the future x
18 hours ago, hopfullady said:Hi, do you guys believe its possible fora large volume of scartissuein aspecific area lets say the abdomen tobe treated with micro coring? If the scars areseparated by healthy skin?
full of the area will be treated with microcoring if scars are separated by healthy skin
Thanks for the info damnBOY, have a lot of hope thanks to you. If the microcoring proves successfull finally we will have something that can remove scar tissue without creating another scar.
Also one more month till the end of preclinicals from Sunogel, lets hope it worked out for them couse honestly I do thing Sunogel might be the ONE!
1 hour ago, AlexZ77 said:Thanks for the info damnBOY, have a lot of hope thanks to you. If the microcoring proves successfull finally we will have something that can remove scar tissue without creating another scar.
Also one more month till the end of preclinicals from Sunogel, lets hope it worked out for them couse honestly I do thing Sunogel might be the ONE!
when sunogel preclinical will end ???
and they are performing preclinical on human or swine ????
Just now, Anish004 said:when sunogel preclinical will end ???
and they are performing preclinical on human or swine ????
It says on their website that they plan to end them by september.
we dont know if they are doing anytrails on humans rn,probably not cause human trials usually start during clinicals
14 hours ago, AlexZ77 said:I have a question, do you guys know when microcoring is coming out to market?
They say they are looking at late 2019 but maybe thats for anti aging purpose first as that trial is done. They have a lot of prerequisites like eg if you have had filler in the scar you need to wait two years post filler, 1 year post fat graft, so long after laser etc so read their patent it will tell you x