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2 hours ago, beautifulambition said:
It depends on the scar. Ice pick is different than what Im talking about. I saw dr pimple poppe Sandra lee said filler of any kind is for rolling scars anyways. Im talking about fibrotic tissue not missing tissue.
Just now, nikki_gargin said:It depends on the scar. Ice pick is different than what Im talking about. I saw dr pimple poppe Sandra lee said filler of any kind is for rolling scars anyways. Im talking about fibrotic tissue not missing tissue.
Thanks though. Useful for some.
Does it need more than a tiny bit of fat?
If only I had enough fat to go around and so much of it didn't get wasted through the process.
I already have weirdly hollow asymmetrical sites from my last fat donation. Not to mention the agony of tolerating the liposuction without general anesthesia when you have a tight low fat body.
Overweight people are so lucky. So many ways fat can get recycled for so many places.
This is a generalized comment as I dont want to debate or have to respond. Educating for the greater good of specifically acne scars, that is the website and sub forum we are on.Thistopic has been side tracked now with treatments instead of scarless healing.
Fat has been around for quite some time, they were using it in the middle age as filler(even animal fat). After helping thousands with their scars that fat is often not a good option for"acne scar." Westopped using it around 2010 as it just was not a good option for the various reason you can read in the links and explanations. Re-absorption, lumpiness, needing to do multiple procedures, it not lasting any longer than a filler, being aggressive - you have to have some lipo to get the fat, high operation / treatment costs, 70-90% of fat does not last and is re-absorbed. Discoloration, a dangerously large cannula is needed and that has had some side effects in the face. Micro was supposed to solve all this but it did not, ... processing meant the fatbroken down quicker.
""Fibrotic scars"", ... most scar cases are fibrotic in nature that are acne scars, ... you have a mixture of discussions above with various kinds of other scars and locations that react differently on the body.
How would injecting fat help when what is needed again this is only for acne scars(this is what I specialize in), need to be broken - the tethers not filled with fat. If you have a widespread underlying atrophy issue of fat loss that is a different matter say your cheek needs a massive(over 3" and deep) fill. Why is fat still used, ... it does great for"wide" spread scars, and body scars needling a massive volume of filler.
I can see it being injected into fibrotic tissue in say surgery scars, but that is not the purpose of this website or forum, it's acne scars.
Some countries it's dirt cheap - eastern Europe, Middle East, Some South Asian Countries. But the rest of the world has moved onto fillers which are much more predictable and often reversible if needed. Like everything treatments change.
Itmight be viable in the future if they could isolate the delicate stem cells and protect them, they cannot now no matter what method they say won't do this. A body scar can be hundreds if not thousands of mm's wide, ... acne scars are only on avg 50 mm(2") and under.
Hope your fat transfer goes well. It is very popular for fake abs(under the muscle) and body reconstruction, not so much for breasts as it can migrate or look uneven.
The future we will see even longer lasting fully reversible fillers, but for now we have some good ones that are highly predictable.
FYI Dr Sam Lam a expert in fat grafting(wrote a book and lectures) as read above from 2010, stopped doing fat grafting in all scar cases then, he had done thousands on rolling, box car and icepick. He now uses fillers.
23 hours ago, nikki_gargin said:It depends on the scar. Ice pick is different than what Im talking about. I saw dr pimple poppe Sandra lee said filler of any kind is for rolling scars anyways. Im talking about fibrotic tissue not missing tissue.
Thanks though. Useful for some.
I don't believe fat grafting is the way to go for acne scars. Fat grafting elevates the skin, that's about it. Scar tissue is devoid of fat tissue which is what normal skin has. I keep repeating this but Cotsarelis and his team found a way to turn scar tissue into fat tissue which signals the development of skin pores and the skin remodels into normal looking skin again. Now this is from Cotsarelis who promises a cure for baldness for years but has yet to deliver.
When it comes to fat grafting, the body will not keep it in place and it might get lost in a few years. The body will not regenerate what is lost because scar tissue is there. With scar tissue, the body just accepts it and will do nothing unless off course you re-injure the scar.
2 hours ago, MyBeautifulScars said:I don't believe fat grafting is the way to go for acne scars. Fat grafting elevates the skin, that's about it. Scar tissue is devoid of fat tissue which is what normal skin has. I keep repeating this but Cotsarelis and his team found a way to turn scar tissue into fat tissue which signals the development of skin pores and the skin remodels into normal looking skin again. Now this is from Cotsarelis who promises a cure for baldness for years but has yet to deliver.
When it comes to fat grafting, the body will not keep it in place and it might get lost in a few years. The body will not regenerate what is lost because scar tissue is there. With scar tissue, the body just accepts it and will do nothing unless off course you re-injure the scar.
Maybe not for acne scars then. But like you said fat being delivered into the scar tissue does help make it appear more normal according to the research.
i wasnt looking to debate @beautifulambitionJust sharing the info I found in research papers. I appreaciate perhaps not useful to majority of people here but still worth sharing as people may have surgical scars also.
@nikki_gargin No problem with you posting or talking about whatever
, I know there are all different types of scars here. Was clarifying as I had way to many emails asking me about fat and "acne scars" after that. Just want to clarify.
Hi guys!
I would like to ask you a question. Im 18 rn and I have some scarring on my back from acne and I fully understand that right now its not possible to fix it but I would love to have at least hope. Do you think scarless healing will be possible within the next 20 years, like can we say for sure that by 2040 thereis very high chance that there will be treatments that could regenerate skin?
Btw sry for my english its not my first language
5 hours ago, AlexZ77 said:Hi guys!
I would like to ask you a question. Im 18 rn and I have some scarring on my back from acne and I fully understand that right now its not possible to fix it but I would love to have at least hope. Do you think scarless healing will be possible within the next 20 years, like can we say for sure that by 2040 thereis very high chance that there will be treatments that could regenerate skin?
Btw sry for my english its not my first language
If the world hasn't ended by then, yep for sure come back in 20 years
On 6/14/2019 at 8:07 PM, AlexZ77 said:Hi guys!
I would like to ask you a question. Im 18 rn and I have some scarring on my back from acne and I fully understand that right now its not possible to fix it but I would love to have at least hope. Do you think scarless healing will be possible within the next 20 years, like can we say for sure that by 2040 thereis very high chance that there will be treatments that could regenerate skin?
Btw sry for my english its not my first language
20 years....I reckon within 10. Birchbiomed have 3 months left on a trial. So lets see how that turns out as a it of a feeler.
I know everyone here is meh SkinTE but they are the first of a kind. Its like the first computer game...now look where we are. Also things upgrade quick. Perfection 100% perfect maybe will be 20 or 30 years. But 90% will be much sooner. Like now games are only getting marginally better in quality because its nearly perfect, compared to the leap into then 00s and late 90s with 3D etc from 2d 70s and 80s
13 hours ago, nikki_gargin said:20 years....I reckon within 10. Birchbiomed have 3 months left on a trial. So let™s see how that turns out as a it of a œfeeler.
I know everyone here is meh SkinTE but they are the first of a kind. It™s like the first computer game...now look where we are. Also things upgrade quick. Perfection 100% perfect maybe will be 20 or 30 years. But 90% will be much sooner. Like now games are only getting marginally better in quality because it™s nearly perfect, compared to the leap into then 00s and late 90s with 3D etc from 2d 70s and 80s
So, there are several start ups involved in hypertrophic/keloid scar research or treatment development. Many are trying to use gene therapy to silence some genes. One such drug is RXI109 which went through 2 clinical trials already. The company behind this drug changed names recently to Phio Pharmaceuticals. However, we don't have any news regarding further trials for many months.
Another company to watch is OLiX Pharmaceuticals. Both startups are using RNA to alter DNA and suppress the formation of fibroblasts which are responsible for scar tissue. RNA sequencing is a bit of an ancestral method of synthesizing proteins. Living organisms still use this method to repair damaged DNA. DNA is basically two copies of RNA, viruses cannot repair damaged DNA as they only one strand of RNA, so viruses are still considered living organisms however scientists view them as some sort of primordial or beginning stages of life.
Here are some results of RXI-109.
My guess is that FS2 should give you similar results. Kynurenine seems to play an important role in suppressing fibroblasts as well.
So as you can see, we are at the beginning stages of scar treatments. Lasers have been around for a decade or so and most dermatologists are moving away from these, they rather use subcision, fillers or TCA peels for atrophic scars. For hypertrophic scars, lasers still work best because they burn away the excess tissue.
ScarX pharmaceuticals is another company involved in developing another promising drug codenamed SCX-001. They have found that yet another protein beta-catenin is involved in scar formation.
FS2, RXi-109, OLX101 and SCX-001 are all in the beginning stages of development and will take several years to market.
Polarity likes to advertise itself as the next alternative to regenerate skin but I'm skeptical. The company has had its ups and downs over the last 2 years. Many here were overhyped about them in 2017 but they slowly disappeared from the board. The few pics they have released are not scarless although the healing outcome may be better for some patients. Sunogel is another startups making bold claims like Polarity. Their website hasn't been updated for a while but it does state that by the end of this year, they should move ahead. Micro-coring is yet another method which some here swear off. We all know that it will take many treatments and years to remove scars this way.
There are other companies I have not listed here and I believe I provide an unbiased perspective on this topic. Some members have gone into private boards promoting certain startups. I feel they have a hidden agenda and don't want to be exposed.
This to say that for scarring, I believe we would need to wait several years. The scar treatment market will witness exponential growth in the coming years.
5 hours ago, MyBeautifulScars said:So, there are several start ups involved in hypertrophic/keloid scar research or treatment development. Many are trying to use gene therapy to silence some genes. One such drug is RXI109 which went through 2 clinical trials already. The company behind this drug changed names recently to Phio Pharmaceuticals. However, we don't have any news regarding further trials for many months.
Another company to watch is OLiX Pharmaceuticals. Both startups are using RNA to alter DNA and suppress the formation of fibroblasts which are responsible for scar tissue. RNA sequencing is a bit of an ancestral method of synthesizing proteins. Living organisms still use this method to repair damaged DNA. DNA is basically two copies of RNA, viruses cannot repair damaged DNA as they only one strand of RNA, so viruses are still considered living organisms however scientists view them as some sort of primordial or beginning stages of life.
Here are some results of RXI-109.
My guess is that FS2 should give you similar results. Kynurenine seems to play an important role in suppressing fibroblasts as well.
So as you can see, we are at the beginning stages of scar treatments. Lasers have been around for a decade or so and most dermatologists are moving away from these, they rather use subcision, fillers or TCA peels for atrophic scars. For hypertrophic scars, lasers still work best because they burn away the excess tissue.
ScarX pharmaceuticals is another company involved in developing another promising drug codenamed SCX-001. They have found that yet another protein beta-catenin is involved in scar formation.
FS2, RXi-109, OLX101 and SCX-001 are all in the beginning stages of development and will take several years to market.
Polarity likes to advertise itself as the next alternative to regenerate skin but I'm skeptical. The company has had its ups and downs over the last 2 years. Many here were overhyped about them in 2017 but they slowly disappeared from the board. The few pics they have released are not scarless although the healing outcome may be better for some patients. Sunogel is another startups making bold claims like Polarity. Their website hasn't been updated for a while but it does state that by the end of this year, they should move ahead. Micro-coring is yet another method which some here swear off. We all know that it will take many treatments and years to remove scars this way.
There are other companies I have not listed here and I believe I provide an unbiased perspective on this topic. Some members have gone into private boards promoting certain startups. I feel they have a hidden agenda and don't want to be exposed.
This to say that for scarring, I believe we would need to wait several years. The scar treatment market will witness exponential growth in the coming years.
They are very good pictures for 3 months. Less tightening of surrounding tissues and not hypertrophic. If I had that drug I wouldn™t have some of the issues I have now.
Like you said it™s early stages but the market seems to be really into this science. University of Birmingham UK have said they aim to make scarring history within a generation. Bold claim.
Btw, this is not the holy grail or anything. But i've been taking NAD+ supplements for 1 year plus and noticed some difference in my scars. Like they have become less pronounced. Nad+ is said to be able to reverse aging and replenish cells. It might had an effect on my scars looking better.
Maybe someone else can try this method and report if similar improvements?
3 hours ago, AI3forever said:Btw, this is not the holy grail or anything. But i've been taking NAD+ supplements for 1 year plus and noticed some difference in my scars. Like they have become less pronounced. Nad+ is said to be able to reverse aging and replenish cells. It might had an effect on my scars looking better.
Maybe someone else can try this method and report if similar improvements?
those difference can be from this supplement also or can be natural also....also what type of changes in ur scar u r talking about please xplaim
is it scar depth or elevation or its texture or something else
5 hours ago, Anish004 said:those difference can be from this supplement also or can be natural also....also what type of changes in ur scar u r talking about please xplaim
is it scar depth or elevation or its texture or something else
Scars look softer and smoother now. Probably a little improvement of everything. Like if you are short sighted taking off your spectacles willmake any details less pronounced. Kind of like that with my scars before and after.
I will go on to say my scars now look moderate-ish when it was severe before. Take note though from many people post minor scars as moderate, my moderate is probably severe to them.
Initially, I took these pills to look younger.Once I had someone commenting on me looking like a teen. (Could be the way I dress or that genetically I have a naturally boyish face). Im 30 btw. Most people usually guess me a few years younger or ask me if im still schooling.
Because of the effect of the pills replenishing my cells, it could have made my scars less pronounced.
Also, there are other benefits of these pills. Purpotedly, it gives an energy boost and also helps in weight loss and muscle growth too.
For energy boost, I did not see any effect but it could be because I have constant depression it messes up with my energy/mood.
I did see some weight loss/muscle growth but i alsohave been eating rather healthily and working out.
I recommend trying these pills if you want an alternative scar treatmentmethod. Also, the other benefits it has is also a plus.
18 hours ago, AI3forever said:Scars look softer and smoother now. Probably a little improvement of everything. Like if you are short sighted taking off your spectacles willmake any details less pronounced. Kind of like that with my scars before and after.
I will go on to say my scars now look moderate-ish when it was severe before. Take note though from many people post minor scars as moderate, my moderate is probably severe to them.
Initially, I took these pills to look younger.Once I had someone commenting on me looking like a teen. (Could be the way I dress or that genetically I have a naturally boyish face). Im 30 btw. Most people usually guess me a few years younger or ask me if im still schooling.
Because of the effect of the pills replenishing my cells, it could have made my scars less pronounced.
Also, there are other benefits of these pills. Purpotedly, it gives an energy boost and also helps in weight loss and muscle growth too.
For energy boost, I did not see any effect but it could be because I have constant depression it messes up with my energy/mood.
I did see some weight loss/muscle growth but i alsohave been eating rather healthily and working out.
I recommend trying these pills if you want an alternative scar treatmentmethod. Also, the other benefits it has is also a plus.
thatweight lossthing is not good for me...as i am already very undedweight due to strict acne diet...once i used to wear L size tees now even S size runs loose for me...all credits to acne
On 6/19/2019 at 4:47 AM, AI3forever said:Scars look softer and smoother now. Probably a little improvement of everything. Like if you are short sighted taking off your spectacles willmake any details less pronounced. Kind of like that with my scars before and after.
I will go on to say my scars now look moderate-ish when it was severe before. Take note though from many people post minor scars as moderate, my moderate is probably severe to them.
Initially, I took these pills to look younger.Once I had someone commenting on me looking like a teen. (Could be the way I dress or that genetically I have a naturally boyish face). Im 30 btw. Most people usually guess me a few years younger or ask me if im still schooling.
Because of the effect of the pills replenishing my cells, it could have made my scars less pronounced.
Also, there are other benefits of these pills. Purpotedly, it gives an energy boost and also helps in weight loss and muscle growth too.
For energy boost, I did not see any effect but it could be because I have constant depression it messes up with my energy/mood.
I did see some weight loss/muscle growth but i alsohave been eating rather healthily and working out.
I recommend trying these pills if you want an alternative scar treatmentmethod. Also, the other benefits it has is also a plus.
I read through that , looks good , which specific brand you use ?? And what is the dosage ?? Does it work on hairs ?? Like less thining Or reversing greying ?
21 hours ago, Ravi.kumar.engineer said:I read through that , looks good , which specific brand you use ?? And what is the dosage ?? Does it work on hairs ?? Like less thining Or reversing greying ?
Previously was using Tru Niagen, but due to costs switched tousing Thorne Niacel-250. I take two pills per day which is 500mg.
I think it might work on hairs too. Theres some articles and people claiming that it helps online. No harm trying tosee whether you like the results.
11 hours ago, AI3forever said:Previously was using Tru Niagen, but due to costs switched tousing Thorne Niacel-250. I take two pills per day which is 500mg.
I think it might work on hairs too. Theres some articles and people claiming that it helps online. No harm trying tosee whether you like the results.
Sure thanks for updating , so how long I should wait to see any changes ??
Whats the feeling on micro coring by Cytrellis and Recros Medica whether it will help some scars and it possibly being made available later this year?
Recros medica has a single scalpet 1.5mm for scar resectionand tattoo removal though looks more for body than face.Not sure how scarless 1.5mm coring will be, i think the diameter of the 22 gauge needle Cytrellis use is 0.64mm which they say heals without scarring at this range. Cytrellis is going to release its data from its acne scar trial about November.
Obviously accuracy is a key point to assure only unwanted scar tissue is removed. My main concern with this treatment is when that scar portionis cored out will the edges come together (healthy skin or scared skin) and close the skin up as they say essentially eliminating that portion of the scar making the overall scar much smalleror eliminating it all together....or will it just fill itself with new scar tissue?
Alot of my scars are quite small/finenow almost like scalpel line width with poor texture the main concern. My only goal now is to remove those markings that cause the uneven appearance and subtle rolling nature.All my treatments to date have been based on disruption and breaking down scar tissue to reorganize but the remnants ofthe original scar remain even if considerably smaller now, so it came to my attention ive never had a treatment that actually removes the scar tissue. Take it out completely, Adios.
And if FS2 or OLX101 offers some sort of success at least in reducing scar tissue im sure both treatments combined with Micro coringcould behelpful. Fingers crossed
As for Sunogel who really knows, it seems like just a pipe dream atm.
18 hours ago, AI3forever said:Previously was using Tru Niagen, but due to costs switched tousing Thorne Niacel-250. I take two pills per day which is 500mg.
I think it might work on hairs too. Theres some articles and people claiming that it helps online. No harm trying tosee whether you like the results.
Thanks for the information! Are you taking other supplements with this as well?
12 hours ago, Ravi.kumar.engineer said:Sure thanks for updating , so how long I should wait to see any changes ??
I only suddenly felt my skin was smoother after slightly more than a year. But it could be I didnt realize the improvements until now.
I would say give it at least 3-6 months for full effect. It will take sometime for a body to change like how onecannot expect to be fat to slim too fast even if they were doing exercises/eating right.
7 hours ago, Athina1999 said:Thanks for the information! Are you taking other supplements with this as well?
No, but ive been eating pretty healthily.