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Whats the feeling on micro coring by Cytrellis and Recros Medica whether it will help some scars and it possibly being made available later this year?
Recros medica has a single scalpet 1.5mm for scar resectionand tattoo removal though looks more for body than face.Not sure how scarless 1.5mm coring will be, i think the diameter of the 22 gauge needle Cytrellis use is 0.64mm which they say heals without scarring at this range. Cytrellis is going to release its data from its acne scar trial about November.
Obviously accuracy is a key point to assure only unwanted scar tissue is removed. My main concern with this treatment is when that scar portionis cored out will the edges come together (healthy skin or scared skin) and close the skin up as they say essentially eliminating that portion of the scar making the overall scar much smalleror eliminating it all together....or will it just fill itself with new scar tissue?
Alot of my scars are quite small/finenow almost like scalpel line width with poor texture the main concern. My only goal now is to remove those markings that cause the uneven appearance and subtle rolling nature.All my treatments to date have been based on disruption and breaking down scar tissue to reorganize but the remnants ofthe original scar remain even if considerably smaller now, so it came to my attention ive never had a treatment that actually removes the scar tissue. Take it out completely, Adios.
And if FS2 or OLX101 offers some sort of success at least in reducing scar tissue im sure both treatments combined with Micro coringcould behelpful. Fingers crossed
As for Sunogel who really knows, it seems like just a pipe dream atm.
18 hours ago, AI3forever said:Previously was using Tru Niagen, but due to costs switched tousing Thorne Niacel-250. I take two pills per day which is 500mg.
I think it might work on hairs too. Theres some articles and people claiming that it helps online. No harm trying tosee whether you like the results.
Thanks for the information! Are you taking other supplements with this as well?
12 hours ago, Ravi.kumar.engineer said:Sure thanks for updating , so how long I should wait to see any changes ??
I only suddenly felt my skin was smoother after slightly more than a year. But it could be I didnt realize the improvements until now.
I would say give it at least 3-6 months for full effect. It will take sometime for a body to change like how onecannot expect to be fat to slim too fast even if they were doing exercises/eating right.
7 hours ago, Athina1999 said:Thanks for the information! Are you taking other supplements with this as well?
No, but ive been eating pretty healthily.
11 hours ago, Lapis lazuli said:Thanks for posting these results. I see six photos all of which I see scarring in. So that's not a very promising result in my eyes.
Yes nobody said it would be perfect. I was just highlighting what researchers have able to accomplish thus far with a drug currently in development codenamed RXi-109.
This video contains the names Verpaleand Tonnard. These are plasticsurgeons in private clinic in Belgium. I have visited both. Tonnarddid not show any interest and just offered the general laser/croton oil peel. His colleague Verpalewasmore attentive and answered the guestions. What stopped me: theempty clinic - not much patients. When I asked Tonnard about the price of lipofilling with Sub he said smth around 4000euro. And Verpale said 8000euro! When I said that a different price was given by Tonnard he said that Tonnard was mistaken but quickly dropped the price to 6000euro))) after such a game with a price and no official price list given I left. I went to another fat surgeon Stillaert. Who knows above mentioned Drs very well. He works in the state hospital and the price was around 3000euro. He wornedme that fat was unpredictable and it depends on your individual absorption rate how much would stay. What I did not not understand then that fat molecule was too big to fill in the individual pits. It is more for wavy skin where the bigger areas are sunken. He also said that Nanofat was absolutely useless because of the newest research, by centrifuging fat to the nanofat state all the stem cells die. So all the fat dissolved in 3 months and the surgeon showed no interested any more.Just said you can come for the second time For he same operation. Obviously I did not. Also it was no need to put me under general anaesthetic which I did not understand that time. So he did fat injections, my legs were severely bruised for a month, face also, all dissolved, money gone. I would not recommendfat to anyone with acne scars unless you have wide spread areas of lost tissue. It is for overall volume and no guarantees how much stays.
7 hours ago, Sibel said:This video contains the names Verpaleand Tonnard. These are plasticsurgeons in private clinic in Belgium. I have visited both. Tonnarddid not show any interest and just offered the general laser/croton oil peel. His colleague Verpalewasmore attentive and answered the guestions. What stopped me: theempty clinic - not much patients. When I asked Tonnard about the price of lipofilling with Sub he said smth around 4000euro. And Verpale said 8000euro! When I said that a different price was given by Tonnard he said that Tonnard was mistaken but quickly dropped the price to 6000euro))) after such a game with a price and no official price list given I left. I went to another fat surgeon Stillaert. Who knows above mentioned Drs very well. He works in the state hospital and the price was around 3000euro. He wornedme that fat was unpredictable and it depends on your individual absorption rate how much would stay. What I did not not understand then that fat molecule was too big to fill in the individual pits. It is more for wavy skin where the bigger areas are sunken. He also said that Nanofat was absolutely useless because of the newest research, by centrifuging fat to the nanofat state all the stem cells die. So all the fat dissolved in 3 months and the surgeon showed no interested any more.Just said you can come for the second time For he same operation. Obviously I did not. Also it was no need to put me under general anaesthetic which I did not understand that time. So he did fat injections, my legs were severely bruised for a month, face also, all dissolved, money gone. I would not recommendfat to anyone with acne scars unless you have wide spread areas of lost tissue. It is for overall volume and no guarantees how much stays.
Agree with everything. But I am more interested in micro needling with nanofat. I already did sub with sculptra and most of my scars are textural now. Fat , prp doesn't work when injected.
Binga, you can always try. With needling fat goes to the superficial layers. But again if this fat already been centrifuged and no stem cells left then what is the point.. then one more thing: fat taken from your belly is different from your face. No guarantees that it stays or does smth. I did fat injections to the lips as well, all dissolved completely.
Don't know if this has already been posted but here it is regardless:
It's about FS2 where they say that FS2 isn't scarless healing but merely provides cosmetic enhancement, if I understood correctly in the last section of the article.
Maybe it can help a lot of people "get over" their scars if said enhancement is great enough.
The photos of RXI-109-1402 in action anger me more the more I think of them. They are clearly total bullsh*t where the drug has very little to no effect which we can see especially clearly in the first two cases where it's like a plastic surgeon once told me how when you cut a scar out and let it heal again, the edges of the wound are closer to each other due to contraction which always happens during the healing process. The drug didn't allow for any skin to regenerate. If it had, you could just keep on going until all skin regenerated and there would be no reason to call it a day after one excision.
On 7/8/2019 at 5:46 PM, Lapis lazuli said:Don't know if this has already been posted but here it is regardless:
It's about FS2 where they say that FS2 isn't scarless healing but merely provides cosmetic enhancement, if I understood correctly in the last section of the article.
Maybe it can help a lot of people "get over" their scars if said enhancement is great enough.
The photos of RXI-109-1402 in action anger me more the more I think of them. They are clearly total bullsh*t where the drug has very little to no effect which we can see especially clearly in the first two cases where it's like a plastic surgeon once told me how when you cut a scar out and let it heal again, the edges of the wound are closer to each other due to contraction which always happens during the healing process. The drug didn't allow for any skin to regenerate. If it had, you could just keep on going until all skin regenerated and there would be no reason to call it a day after one excision.
We are in the beginning stages of this. There is still no anti scarring drugs prescribed or available over the counter that offer any improvement.
FS2 may provide better results than RXi-109. We just don't know. If it helps with keloid or hypertrophic by making them leveled with the rest of the skin, I think many people will be happy. FS2 most likely doesn'twork for acne scars as they are atrophic in nature. We have already talked about that before.
This thread is massive and I can't find answers. Is there anyone with scientific knowledge that can say if scarless healing is possible? And if so can they give a conservative estimate as to when that will be? I am just assuming it is unlikely we will see a huge leap in dermatologic treatments in the next 20 years, but that's just my realism talking with no scientific knowledge whatsoever.
12 hours ago, glimfeather said:This thread is massive and I can't find answers. Is there anyone with scientific knowledge that can say if scarless healing is possible? And if so can they give a conservative estimate as to when that will be? I am just assuming it is unlikely we will see a huge leap in dermatologic treatments in the next 20 years, but that's just my realism talking with no scientific knowledge whatsoever.
Possible? Def yes the question shouldnt be if its possible, but if its achievable and viable to the public in a near future.
Studies already shown that wound in fetus heal scarlessly so definately is possible to. But science needs to solve the puzzle to how that can happen in a mature human being.
On 7/23/2019 at 6:40 PM, glimfeather said:This thread is massive and I can't find answers. Is there anyone with scientific knowledge that can say if scarless healing is possible? And if so can they give a conservative estimate as to when that will be? I am just assuming it is unlikely we will see a huge leap in dermatologic treatments in the next 20 years, but that's just my realism talking with no scientific knowledge whatsoever.
https://www.sunogel.com/pipeline/
They say they will complete preclinical studies by the end of the third quarter of this year!
I also spoke to a doctor when I worked in a hospital who said that it's certain to become a reality (scarless healing) but it's not yet known exactly when.
If one wants to get cynical and say that making money is the primary reason they do anything then I think making scarless healing real is definately their goal as I think one can make the most money that way?
Keep your chin up, mate.
25 minutes ago, Lip121212 said:You guys I haven't been on this forum in months.
1.) When is FS2 projected to come out?
2.) What track is Sunogel on? Are they on fast approval process?
FS2 is in phase 2 clinical trials. This is where most experimental drugs fail. If it doesn't fail, we are looking maybe at 5 to 10 yearsfor commercialization.
Sunogel is taking awfully long. They are in pre-clinical trialswhich means they haven't started phase 0. They should start phase 0 at the end of 2019 according to their website. We are looking at 20 years provided their product doesn't fail at phase 0, 1 or 2.
11 hours ago, MyBeautifulScars said:FS2 is in phase 2 clinical trials. This is where most experimental drugs fail. If it doesn't fail, we are looking maybe at 5 to 10 yearsfor commercialization.
Sunogel is taking awfully long. They are in pre-clinical trialswhich means they haven't started phase 0. They should start phase 0 at the end of 2019 according to their website. We are looking at 20 years provided their product doesn't fail at phase 0, 1 or 2.
20 years lmaooooo you dont have a clue
19 hours ago, MyBeautifulScars said:Sunogel is taking awfully long. They are in pre-clinical trialswhich means they haven't started phase 0. They should start phase 0 at the end of 2019 according to their website. We are looking at 20 years provided their product doesn't fail at phase 0, 1 or 2.
Sunogel's CEO(?) said that someone told him he'd rather die than continue living with scars and the CEO said that there was no need to kill yourself because Sunogel's product works. I don't think he would have said that if Sunogel's product was 20 years away from becoming available.
As if he's say to the guy "Just hold on for another 20 years and then you can get your scars fixed!". lol
2 hours ago, damnBOY said:20 years lmaooooo you dont have a clue
I bet you do. Do you have anything else worthwhile to say or just trolling. Are you a poster boy of this product? Are you withholding information that we need to know? Are you still advertising false claims in your hidden forums?
2 hours ago, Lapis lazuli said:Sunogel's CEO(?) said that someone told him he'd rather die than continue living with scars and the CEO said that there was no need to kill yourself because Sunogel's product works. I don't he would have said that if Sunogel's product was 20 years away from becoming available.
As if he's say to the guy "Just hold on for another 20 years and then you can get your scars fixed!". lol
They still haven't started clinical trials. Clinical trials take on average 10 years, there are 4 to 5 stages depending in each country, I heard the old rhetoric that it's a device and it shouldn't take so long but consider this: most experimental drugs fail/devices during the clinical trials. Don't hold your breath on Sunogel for now.
What do you expect for the guy to say? Go commit suicide? Get real!! That is such a lame excuse.
This blogshould be as transparent as possible. Too many poster boys. This is why nobody post anything here anymore.
4 hours ago, MyBeautifulScars said:I bet you do. Do you have anything else worthwhile to say or just trolling. Are you a poster boy of this product? Are you withholding information that we need to know? Are you still advertising false claims in your hidden forums?
They still haven't started clinical trials. Clinical trials take on average 10 years, there are 4 to 5 stages depending in each country, I heard the old rhetoric that it's a device and it shouldn't take so long but consider this: most experimental drugs fail/devices during the clinical trials. Don't hold your breath on Sunogel for now.
What do you expect for the guy to say? Go commit suicide? Get real!! That is such a lame excuse.
This blogshould be as transparent as possible. Too many poster boys. This is why nobody post anything here anymore.
Fs2 have said they are looking to get the product to market as soon as possible with the first one next year (if all goes well). Its not going to take 10 years,phase 3 can be limited market release like eg over seen by selected expertslike what skinte done. Phase 4 is full release but keeping an eye on undiscovered side effects.
5 hours ago, MyBeautifulScars said:I bet you do. Do you have anything else worthwhile to say or just trolling. Are you a poster boy of this product? Are you withholding information that we need to know? Are you still advertising false claims in your hidden forums?
They still haven't started clinical trials. Clinical trials take on average 10 years, there are 4 to 5 stages depending in each country, I heard the old rhetoric that it's a device and it shouldn't take so long but consider this: most experimental drugs fail/devices during the clinical trials. Don't hold your breath on Sunogel for now.
What do you expect for the guy to say? Go commit suicide? Get real!! That is such a lame excuse.
This blogshould be as transparent as possible. Too many poster boys. This is why nobody post anything here anymore.
i didnt expect something better from you are u supporting scars and improvements products i havent underastoond your rollin the thread for a long time , firstly the hydrogel from Sunogel is a device (second level) this type of category takes months for fda approval , the problem with sunogel is funding and money.. you are full of negatively, doctor Sun has posted an scientific paper and he clearly shows skin regeneration in porcine models, now you will say aaaahhh skinte showed regeneration in pigs but it didnt work in humans, no polarityte never shows us clearly complete regeneration in pigs with histological examination, In the other hand doctor sun did it take a look in his paper stop spread negativity all over the thread. Also microcoring is going to market by end of 2019 and scientific evidence it has shown that removing in a microscopic way,the cavities the microcoring is makeheals scar free, it doesnt matter what tissue the cavities have near them. the cavities heal scar free the scar is production of inflammatory signals and a-smaproduction which turns fibroblasts to myofibroblasts. with microcoring the inflammaton is small fibroblasts doenst turn to myofibroblasts and fibroblasts migrates intocavities . so,in long termthe scar will be removed completely.its like this: imagine you remove 25% of the skin in the first treatment,after few treatment the scar will be removed 100% .lasers and microneedlingdoesnt work that way lasers deliver heat in the scar it doesnt remove the structure of the scar it doenst remove the ECM of the scar nothing can do this today, the only way you can remove the scar today is with surgery but this will create a new scarif you dont remove the extracellular matrix of the scar dont expect regeneration. thats why fs2 will never bring 100% regeneration neither injectionsneither creams and lasers