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[Sticky] Scarless Healing

 
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(@Anonymous)

Posted : 02/27/2019 3:51 am

On 4/12/2018 at 12:20 PM, surgical scar said:

Sell this idea to a cosmetic doctor and if they'll take the liability wake me up. Hope they'll give package discount for filling the wrinkles too...hello my zillionth birthday!

:)

12 minutes ago, surgical scar said:

Seems like you have a very amusing definition of cussing that moderators did not detect

Haven't been "T" and "GP" dead for some time? Why are you invoking their ghosts? Are you feeling that alone :(

Is your trolling tirade over yet? Like I said I'm entertained and don't want to get moderators into this...but you're pushing it with your meltdown and continued bizarre attacking marathon on everyone in your way

Just curious did your therapist put you on pills?...seems like a massive malfunction

I talked about "my" wrinkles? You posted pictures of wrinkles and you're the one following trials on wrinkles... and I took you to school about them and said I don't need to core out my perfect skin and fat to look aged...

You're very struggling with reading comprehension :(

Go to bed kid...trolling ride is over

you took me to school... lol.. whatever you need to tell yourself.  I'm a grad student in oncology while you are a nurse who probably went to community college.  Maybe you should try being nicer so when your heart goes out in 2 years god can put you in heaven :)

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(@surgical-scar)

Posted : 02/27/2019 3:54 am

Just now, FromScarredtoFree said:

:)

Like I said...reading comprehension and sarcasm is not your thing...

I was saying when your delusional fantasies of Polarity's magic injectables and so on come to fruition, we probably all have wrinkles to worry about.

Stop taking your pills and go to bed XO

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(@Anonymous)

Posted : 02/27/2019 3:56 am

Just now, surgical scar said:

Like I said...reading comprehension and sarcasm is not your thing...

I was saying when your delusional fantasies of Polarity's magic injectables and so on come to fruition, we probably all have wrinkles to worry about.

Stop taking your pills and go to bed XO

I don't need anything for my skin. I'm perfectly happy the way I am because I have more important things to worry about. Maybe you should go to bed so you can get to the early bird special tomorrow.

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(@Anonymous)

Posted : 02/27/2019 4:04 am

While this is all very amusing...perhaps we can divert the topic back to scarless healing and away from attacks on mental health  ;)

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(@surgical-scar)

Posted : 02/27/2019 4:32 am

28 minutes ago, acne_skin_queen said:

While this is all very amusing...perhaps we can divert the topic back to scarless healing and away from attacks on mental health  ;)

Agree

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(@beanbagdog)

Posted : 02/27/2019 2:23 pm

Yeah, I come here to see advances in research and insights on scarless healing. Not whiny naysayers or people telling sob stories, which there has been an abundance of lately.

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(@nikki_gargin)

Posted : 02/27/2019 4:09 pm

19 hours ago, Rez77 said:

 

 

Am I only person who saw the humour in this post?

On 2/26/2019 at 9:13 PM, Anish004 said:

skinte application in a wound which is only deep to skin 

earlier pics we have seen were of damage deep to musclesScreenshot_20190227-103724.thumb.jpg.f1bd580f76bd583978e5856a8beb0ccc.jpg

I think what your looking at is wound contraction and decrease in swelling. The brown blob in middle is only bit which is skinte. Can™t expect it to be perfect at 1 month! It will prob be invisible in 2 years eg remodelled. But that™s a tiny wound. Skinte looks good for what it is. But it™s not for most people on here.

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(@golfpanther)

Posted : 02/28/2019 1:35 am

My goodness, some things never change. I forget about the board for a while and come back to see the same old posters hijackingthe board with overt trolling. I just dont understand why nothing changes. This is the most visited and active resource on the web for news about scarless healing and yet a few seem hellbent to do everything in their power to make it about them.

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(@surgical-scar)

Posted : 02/28/2019 1:55 am

@golfpanther Why did you come back just to hijack and troll this page again? Funny you just did what you claim a few do, which you know "the few" was your friend calling your name out of nowhere in his/her meltdown.

How do you "forget about this board" but land right back to restart the drama once your crying buddy drops your name? Go back and dont cease the opportunity to make this page about you again. Take your trolling buddy too to private chat.

Next post better be about scar trials.

 

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(@Anonymous)

Posted : 02/28/2019 2:00 am

2 minutes ago, surgical scar said:

@golfpanther Why did you come back just to hijack and troll this page again? Funny you just did what you claim a few do, which you know "the few" was your friend calling your name out of nowhere in his/her meltdown.

How do you "forget about this board" but land right back to restart the drama once your crying buddy drops your name? Go back and dont cease the opportunity to make this page about you again. Take your trolling buddy too to private chat.

Next post better be about scar trials.

 

Don't worry about it gramps... Maybe you should try to make your lover Rezz77 feel better since he clearly had some sort of meltdown

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(@mybeautifulscars)

Posted : 03/01/2019 5:31 pm

On 2/28/2019 at 2:00 AM, FromScarredtoFree said:

Don't worry about it gramps... Maybe you should try to make your lover Rezz77 feel better since he clearly had some sort of meltdown

Stop trolling us and go hide in a private forum already. You bring nothing here.

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(@mybeautifulscars)
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(@eternal-maldition)

Posted : 03/02/2019 11:26 pm

So. which are the most promising products to achieve the miracle?

 

 

can someone explain to me why fs2 is so mentioned here?

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(@surgical-scar)

Posted : 03/02/2019 11:40 pm

15 minutes ago, Eternal Maldition said:

So. which are the most promising products to achieve the miracle?

 can someone explain to me why fs2 is so mentioned here? 

Read last page

On 2/25/2019 at 5:36 PM, MyBeautifulScars said:

FS2 is a drug in development from a startup company knownas BirchBiomed. They are based in Vancouver, Canada. Researchers at UBC, University of British Columbia, stumbled upon some research doneyears ago focused around kynurenine acid, an amino acid byproduct.

It was proven way back since 1997, that this byproduct when applied topically on a freshwound had anti scarring properties and other potential health benefits.

There are currently two drugs in development, FS1and FS2. They are in clinical trials. FS1(fibrostop1)has the potential of reversing hair loss (this doesn't apply to male pattern baldness but other forms of alopecia) and halting juvenileor type 1 diabetes. The drug is to be taken orally.

FS2 when applied topically seems to reduceexisting scar tissue. It's makers claim also that scar tissue doesn't form in fresh wounds if the cream is applied from the beginning.

Both drugs are in phase 2 clinical trials in Canada and the US. We have to wait for the conclusion of both trials this summer before we can truly say that itis something revolutionary. Don't forget most drugs fail at this stage.

This drug can be a long due revolutionary medical innovation. I however don't believe it can help with atrophic scars which are those nasty pock marks we get after cysts heal. I believe it can do wonders for hypertrophic scars and keloids.

It can potentially break down the bundles of collagen buildup that give the scar its raised appearance. Over time, the scar becomes leveled with the surroundingskin. You still have a mark of some sorts of the original injury. I suppose it's better than having that nasty raised shiny scar. To what extent it can reduce existing scars nobody knows, even its makers can't say.

Here is more info about them however.

http://www.folliclethought.com/birch-biomed-therapies-for-scarring-alopecia-areata/

It may not be scarless healing but it's a start. Although it seemswhen applied fast on fresh wounds, no scar tissue is generated. This right here suggests that Sunogel has a direct competition.

I would like to share some info about OLX101. Another startup from South Korea. They seem to have found a way to switch off genes that keep scars going forever. They inject the scar with a serum and over time, the markfades. They are in phase 1 trials in the UK and phase 2 in South Korea. Hopefully, they don't fail.

Another yet similar product to FS2 is SCX-001. Apparently, nefopam also has anti scarring properties. They are in phase 1 clinical trials in North America.

1) Info to be found here:

https://clinicaltrials.gov/ct2/show/NCT03036306

2) Scarless Laboraties Inc. is another startup trying to push a peptide to improve scars. Recently given the green light to conduct phase 1 and phase 2 trials.

http://labusinessjournal.com/news/2018/oct/25/ucla-based-scarless-labs-wins-fda-approval-study-s/

3) Similar technology to OLX101

http://www.rxipharma.com/technology/rxi-109/

4) Sirnaomics have been given the green light for phase 2 clinical trials

https://www.prnewswire.com/news-releases/sirnaomics-received-green-light-from-us-fda-for-a-clinical-phase-iia-study-of-its-leading-sirna-therapeutic-candidate-stp705-for-treatment-of-hypertrophic-scar-300358166.html

We are surely getting there but it will take time.

Microcoring is targeting skin laxicity at best and I just don't see how scar tissue can heal scar free when excised. Microcoring is not scar free healing. We are simply not there yet.

 

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(@eternal-maldition)

Posted : 03/03/2019 12:05 am

I like olx101

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(@anish004)

Posted : 03/03/2019 1:32 am

scars are shit and fs2 is another type of shit

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(@surgical-scar)

Posted : 03/03/2019 1:39 am

6 minutes ago, Anish004 said:

scars are shit and fs2 is another type of shit

Childish triggered trolls are another kind of shit

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(@anish004)

Posted : 03/03/2019 2:39 am

58 minutes ago, surgical scar said:

Childish triggered trolls are another kind of shit

lmao fs2 will improve ur scar by 10 % or 20% ..and if saying truth is a childish act then its good to be child rather than fake adults

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(@surgical-scar)

Posted : 03/03/2019 2:45 am

7 minutes ago, Anish004 said:

lmao fs2 will improve ur scar by 10 % or 20% ..and if saying truth is a childish act then its good to be child rather than fake adults

lmao truth...says the delusional one who's waiting for Polarity and microcoring for scarless "regeneration" that doesn't happen.

You have no intelligent argument other than trolling tantrums. Don't waste time.

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(@Anonymous)

Posted : 03/03/2019 3:15 am

I wonder where Allergan are at with the TE-HA for scars? They had an interesting press release last Autumn but it™s all gone very quiet :smileys_n_people_15:

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(@mybeautifulscars)

Posted : 03/03/2019 7:00 am

6 hours ago, acne_skin_queen said:

I wonder where Allergan are at with the TE-HA for scars? They had an interesting press release last Autumn but it™s all gone very quiet :smileys_n_people_15:

https://www.prnewswire.com/news-releases/allergan-highlights-key-growth-drivers-for-medical-aesthetics-300713038.html

They are developing a hydrogel which contains tropoelastin, apparently it improved acne scars by up to 78% in a control group for some patients. The last news we have is from September last year. No news ever since.

6 hours ago, Anish004 said:

lmao fs2 will improve ur scar by 10 % or 20% ..and if saying truth is a childish act then its good to be child rather than fake adults

You don't know how much it improves scars and you are already jumping to conclusions just like you and many others were calling us out when we were skeptical about Polarity. Give this product a chance at least before you say anything about it. You have nothing to lose because it will be most likely, a topical cream, probably cheap as an over the counter product and not invasive. 

We all know that FS2 won't get you perfect skin but it's a start. Also, nobody has perfect skin. If you want to look like some model who touches up their pics on Instagram, then scarless healing even if achieved will never satisfy you. There are kids out there every day that develop burn contracture scars that will have severe disfigurement for the rest of their lives, your little facial pockmarks are not so bad if you think of it. And you want perfect skin. I believe you are a narcissist at best and therapy is the best alternative for you. 

Back then, we had people behind Mederma tell us it prevented scars. People would buy the product and well it was a marketing ploy. I am not saying that FS2 is a miracle solution but there are way too many positives than negatives too discredit the findings right now; compared to others who have made false claims like Polarity. 

We have nothing currently out there that helps with scarring unless you dish out thousands of dollars to get that 10 or 20% improvement from plastic surgeons or derms for your acne scars. Maybe FS2 will fail but if it doesn't it will cost at most 10$ off the counter. That raised scar you have on your knee from a child will probably become level with the rest of the skin and nobody will know except under certain lighting. This is way better than anything currently available at the fraction of the cost. 

Go and throw thousands away on microcoring to let some "professional" injure your skin again miraculously hoping that those holes will heal up scar free after nth treatments. Don't come back here claiming you have marks left behind from the incisions and your skin lacks a certain something. Careful what you wish for. 

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(@eternal-maldition)

Posted : 03/03/2019 10:28 am

Thanks for positive information

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(@eternal-maldition)

Posted : 03/03/2019 12:11 pm

Apply this cream /fs2 or other/ on a wide hypertrophic scar causes the skin to regenerate? how would that be?

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(@mybeautifulscars)

Posted : 03/03/2019 12:44 pm

29 minutes ago, Eternal Maldition said:

Apply this cream /fs2 or other/ on a wide hypertrophic scar causes the skin to regenerate? how would that be?

It reduces the appearance of the scar over time. The skin doesn't regenerate by definition. How it does this, nobody knows except it's inventors.They most likely have patented their discovery, so we will never know for several years, patents are good for 100 years. As I stated before, the cream is based on kynurenunine acid which research suggestsway back since 1997, that it has anti-scarring properties.

Scarring itself is a type of skin regeneration. It's a natural part of the healing process. The body acts fast and seals the wound, doesn't care about aesthetics to avoid further infection.

Scar tissue is composed of collagen just like the rest of the skin but it lacks skin pores, melanin and hair follicles. Scar tissue is aligned in one direction as compared to the rest of the skin which collagen is layed down in a random pattern. Hypertrophic or keloid scarring is anoverexpression of collagen, a build up if this protein which produces a very unpleasant lookingscar.

The people behind FS2 claim that it prevents scar formation in new wounds. They don't say if pores, melanin and hair follicles regenerate. The only way to avoid scar formation however is to somehow regenerate pores and hair follicles. That's all I know for now and hopefully FS2 doesn't fail. Clinical trials should end this summer. Phase 3 should start shortly after. Success rate for drugs however is very low at stage 2 trials.

Let's stop the negativity and focus on the positives as people behind FS2 seem to be heading towards the right direction. Sunogel has been around since 3 years ago, even before and there doesn't seem to be any willingness from its maker to move ahead.

I am also looking forward to OLX101 whichswitches off genes to reverse all this collagen buildup. Clinical trials will tell if it truly works. This is a form of gene therapy. Also research at UCI under Cotsarelisis advancing.

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(@ai3forever)

Posted : 03/03/2019 8:10 pm

7 hours ago, MyBeautifulScars said:

Also research at UCI under Cotsarelisis advancing.

Didn't he managed scarless healing in mammals a few years ago? What other research were there?Is he going to makehis treatments public to the masses?

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