Acne.org Products
21 hours ago, Candy Says said:21 hours ago, nikkigirl said:I don't think we will ever have anything that actually gives scarless healing.
why?
Because since this thread has been going on for over 10 years....nothing has been found. I don't think a human and a cat will ever mate either. Sure anything is possible but the odds are against it. There is a lot of things humans will never accomplish.
20 hours ago, MyBeautifulScars said:Scarless healing will be possible one day. For the immediate future, no. They have only begun researching the potential of stem cells and how to change certain cells into other types of cells.With all these failed attempts to tackle scarring, they have made great progress. They have found a way to turn myofibroblasts into normal looking skin.
Myofibroblasts are what replace injured skin and any other types of injured tissue in mammals. The process is called fibrosis. The medical field is only starting to treat it as a disease. They however continue to treat scarring as a normal healing process because we have nothing else that can give a better outcome.
These cells are of different quality than normal skin cells. They are a patchwork to seal a wound quickly and effectively to prevent infection. Obviously, these cells are of inferior quality. Other animals are able to produce a blastema and thus regenerate including reptiles and less complex organisms. Mammals are not capable of this.
The key is to turn these fibroblasts into adipocytes, fat cells. The fat cells trigger the regeneration of hair follicles thus giving us a aesthatically great healing results.
A paper was published in early 2017 and posted often on this forum by a team headed by George Cotsarelis and Maksim Pilkus. The study was performed at UCI Penn University. Unfortunately, they have remained silent every since. They found a way to turn these fibroblasts into adipocytes.
It can take another 10 years but we are getting there slowly and surely.
20 hours ago, MyBeautifulScars said:Scarless healing will be possible one day. For the immediate future, no. They have only begun researching the potential of stem cells and how to change certain cells into other types of cells.With all these failed attempts to tackle scarring, they have made great progress. They have found a way to turn myofibroblasts into normal looking skin.
Myofibroblasts are what replace injured skin and any other types of injured tissue in mammals. The process is called fibrosis. The medical field is only starting to treat it as a disease. They however continue to treat scarring as a normal healing process because we have nothing else that can give a better outcome.
These cells are of different quality than normal skin cells. They are a patchwork to seal a wound quickly and effectively to prevent infection. Obviously, these cells are of inferior quality. Other animals are able to produce a blastema and thus regenerate including reptiles and less complex organisms. Mammals are not capable of this.
The key is to turn these fibroblasts into adipocytes, fat cells. The fat cells trigger the regeneration of hair follicles thus giving us a aesthatically great healing results.
A paper was published in early 2017 and posted often on this forum by a team headed by George Cotsarelis and Maksim Pilkus. The study was performed at UCI Penn University. Unfortunately, they have remained silent every since. They found a way to turn these fibroblasts into adipocytes.
It can take another 10 years but we are getting there slowly and surely.
To say that scarless healing will someday be possible and it can take only 10 years is purely speculation. The world might not be around in 10 years....maybe the sun will flare up and destroy life as we know it.....purely speculation.....nobody will know until it happens.
49 minutes ago, nikkigirl said:There is a lot of things humans will never accomplish.
like laser treat your eyesight to perfection.
Im not trolling or anything, im not gonna wait for something to come, I am treating my skin with current methods.
But... skin can regenerate itself. Not like we want but still. Scientist just needs to turn regeneration to the way we like:)
I actually think, that it much closer than we guess. Think about this - I walked today in Moscow and saw HUNDREDS of beauty and aesthetic clinics. All of them treat skin. How many doctors, companies, projects would be ruined if there will be a product that can cure almost any skin problem? skin care is ultimately large business, no one want to be replaced by superior products.
But then I think about soldiers and burn victims, and all theories about doctors conspiracy goes to trashcan. Actually, its not my thoughts I wrote above.
ps. sorry mods, but I have to say: @surgical scar you are an asshole. No need to response, I will not see your messages.
1 hour ago, nikkigirl said:Because since this thread has been going on for over 10 years....nothing has been found. I don't think a human and a cat will ever mate either. Sure anything is possible but the odds are against it. There is a lot of things humans will never accomplish. To say that scarless healing will someday be possible and it can take only 10 years is purely speculation. The world might not be around in 10 years....maybe the sun will flare up and destroy life as we know it.....purely speculation.....nobody will know until it happens.
The number I gave is purely speculative. It can take 10 or 300 years. I don't know. I am just saying they found a method to turn scar tissue into normal looking tissue.
13 hours ago, damnBOY said:Ok mister Iknoweverything this is the key yeah are u a goru of scarless skin? How did u find it will be 10 years ?? Lmaoooo
I just provide information from research I do online. 10 years is a speculative number. What do you do apart from trolling? Can you post something relevant?
@surgicalscar
Some people here don't see SkinTE is a scam. Don't bother changing their point of view.
22 minutes ago, MyBeautifulScars said:Some people here don't see SkinTE is a scam. Don't bother changing their point of view.
pfff. I called him an asshole because of his behavior and words choosing. Im not skinte "supporter", if you would like to check my posts in this thread, you would realize that I was skeptical about polarity all the time. I left private chat long time ago after realizing that these talks doesn't matter if product is not in my doc's office. And if I would be a "supporter" does it even matter? I will forget about all of you motherfuckers once I'll do my last peel and show result to the forum.
Laughing at people's hopes is filthy. That's why he is an asshole.
8 hours ago, Candy Says said:And if I would be a "supporter" does it even matter? I will forget about all of you motherfuckers once I'll do my last peel and show result to the forum.
Make sure you at least keep your word. So dont forget to link me your results so I can see if peels were ever worth raving about. Then you can forget about us after.
what you guys are looking for is 100 percent new skin. THAT WILL NOT HAPPY ANY TIME SOON (at least not within the next 5-10 years).
For someone to come to a simple solution to this would require a true miracle since it would also mean you could have young perfect skin forever. It would be one part of the fountain of youth.
The problem is also that collagen and elastin and atrophy begins to happen to acne scars so they get deeper and look worse. Right now the best you can do is microneedling (many sessions); lasers (again many sessions) plus subcision and excision plus TCA cross plus fat injections plus restylyne injections. If you do ALL of the above and spend close to 30 grand I would say you can maybe 50 percent improvement on your scars. Which listen, isn't that bad at all. Its actually very good. But that is all you can do for the next 10 years to improve acne scars. So instead of wasting time on this forum go make the 30-50 grand USD its gonna cost you so you can at least live your life.
On 7/4/2018 at 10:26 AM, Tano1 said:If they are guilty of lying about their products capability, then they deserve to fail and thats that.
Therein lies the misconception about the Citron report.
There is no suggestion or evidence (yet!) that Polarity lied about the efficacy or capability of their product. Even Citron made it clear in the 2nd paragraph of their report that ..."Citron will not discuss the science behind Polaity TE because it's irrelevant."
The issue that Citron raised is that Polarity TE failed to notify the markets that they had received final rejection of their patent application.
It's not even that Polarity claimed they had a patent. However, they mislead the market by suggesting that there was a risk their patent application could be rejected...when in fact, the application had already been rejected! (A sneaky snake move, right!)
This lack of candour meant that people were buying Polarity Stock stock at high prices, without knowing this fundamental fact.
So...to clarify, the Citron report was about Polarity's shady stock price manipulation, rather than the efficacy of their product.
It is reasonable to ask.. if they can hide a patent rejection, what else could Polarity be hiding from the market?
However, there is no evidence (yet!) to suggest that they are lieing about the capability of their product.
1 hour ago, HCAS said:Therein lies the misconception about the Citron report.There is no suggestion or evidence (yet!) that Polarity lied about the efficacy or capability of their product. Even Citron made it clear in the 2nd paragraph of their report that ..."Citron will not discuss the science behind Polaity TE because it's irrelevant."
The issue that Citron raised is that Polarity TE failed to notify the markets that they had received final rejection of their patent application.
It's not even that Polarity claimed they had a patent. However, they mislead the market by suggesting that there was a risk their patent application could be rejected...when in fact, the application had already been rejected! (A sneaky snake move, right!)
This lack of candour meant that people were buying Polarity Stock stock at high prices, without knowing this fundamental fact.
So...to clarify, the Citron report was about Polarity's shady stock price manipulation, rather than the efficacy of their product.
It is reasonable to ask.. if they can hide a patent rejection, what else could Polarity be hiding from the market?
However, there is no evidence (yet!) to suggest that they are lieing about the capability of their product.
The issue with Polarity is that they claimed they have found a way to regenerate all 3 layers of skin with full appendages. When time came to release photos, the results didn't look good at all.
Big pharma has been attempting to tackle scarring for decades and never found anything that eliminates it completely. It was impossible for 2 young researchers to have found a way to do it just like that. There was no peer reviewed articles. Normally big discoveries like this lead to peer reviewed articles.
Assuming they found a way, instead they rushed to register on the stock market. It all sounded fishy from the start and an attempt to make money. I also find it hard to believe that the institution they did their work would allow them to use, steal intellectual property just like that. The institution would be required to publish an article about the discovery with the institution's name on it.
There was no product. The product they claimed they had was rejected for a patent. It's all downhill from here because someone else has invented it but has yet to commercialize it. If there's no product, there's no business. They need to go back to the drawing boards. And they have a lot of lawsuits to settle for the coming years. I don't believe they can continue to play the sharade any longer. Investors are pulling out slowly leaving them with nothing.
The technology of SkinTE which probably already belongs to another entity and tweaked a little for Polarity can save lives because it could possibly be a substitute to current skin grafts. Issue is that it is prone to infection as documented on here by the "The Recovery of Autome" or something along those lines. Seems this patient developed infection after SkinTE was applied on his wounds. It is not a solution for us acne sufferers to our acne scarring.
25 minutes ago, MyBeautifulScars said:The issue with Polarity is that they claimed they have found a way to regenerate all 3 layers of skin with full appendages. When time came to release photos, the results didn't look good at all.Big pharma has been attempting to tackle scarring for decades and never found anything that eliminates it completely. It was impossible for 2 young researchers to have found a way to do it just like that. There was no peer reviewed articles. Normally big discoveries like this lead to peer reviewed articles.
Assuming they found a way, instead they rushed to register on the stock market. It all sounded fishy from the start and an attempt to make money. I also find it hard to believe that the institution they did their work would allow them to use, steal intellectual property just like that. The institution would have lo7ved to publish an article with their name on it.
There was no product. The product they claimed they had was rejected for a patent. It's all downhill from here because someone else has invented it but has yet to commercialize it. If there's no product, there's no business.
The technology of SkinTE which probably belongs to another entity can save lives because it could possibly be a substitute to current skin grafts. Issue is that it is only prone to infection as documented in here by the "The Recovery of Autome" or something along those lines. It is not a solution for us acne sufferers to our acne scarring.
And I'm saying that you may be proven correct in the future.
But from a purely factual point of view, we do not know (now) whether the product is a failure or not. Pictures are subjective. (Some people here thought the healing was amazing!). Ausome's infection could have been caused by a number of things.
And we do know the Business hasn't been dissolved yet. In fact, after the initial collapse, share prices have crept back up.
So taking an evidence-based view, you are just 'guessing' at this stage. That's not to say your punt might not turn out to be right. But it's still an open question.
On 7/4/2018 at 5:26 PM, Tano1 said:Doesnt look good for PolarityTE at this point Im sure weve all established that. I dont think everyone should be crying and complaining about it though. Several of us have said that we shouldnt ever put all our hope in one basket. If they are guilty of lying about their products capability, then they deserve to fail and thats that.
That was our closest bet for an improvement on current scar treatments because everything else will be a ways away.
In other news, I reached out to Dr. Sun and he replied by asking me for a sample web page of their site that Im almost finished with. Dr. Shen and another are working on improving the site he told me. I dont expect them to use my design, but I more so reached out to him and told him he can use it to get some ideas. It was not much of a surprise that nobody here has offered to help with anything when I posted about this a little while back. From what I heard, they are supposed to start crowd funding and attempting to attract investors soon so this would be crucial for their advertising & getting recognized.
Many here are so persistent on this thread with demanding a solution to their problem, but not many at all want to put any effort into doing anything as I can see here. They just want to be spoon fed and spoiled. Some clearly even wanted Polarity to fail just because they didnt want to be wrong on a forum where nobody cares. Ive learned a lot from the time Ive spent on this thread and in all honesty, I dont think we deserve a cure.
I may have missed out on your earlier post. I may be able to help (as long as it doesn't disclose my information) and maybe some funding.
On 7/4/2018 at 9:23 AM, agelessfrost said:Yes. The only issue with Sunogel is that they're not going through with their human trials.I think people are misunderstanding what I'm saying, with the FS2, a combination of treatments could improve scars radically. It may not be complete regeneration but it will be better than the current treatments available rn.
Wasn't there a whole list of scarless healing product studies? There are other things to look forward to than Sunogel.
That sounds like the product Singapore is working on. It should be available in the next five years.
Any reason why they are not going through human trials? Not enough funding?I messaged Sunogel about using it to treat acne scars awhile ago. They said its one of their goals, no timeframe or how they are going to achieve it though.
16 hours ago, HCAS said:Therein lies the misconception about the Citron report.
There is no suggestion or evidence (yet!) that Polarity lied about the efficacy or capability of their product. Even Citron made it clear in the 2nd paragraph of their report that ..."Citron will not discuss the science behind Polaity TE because it's irrelevant."
No no I didnt mention Citron there at all. I read the report as well. I was stating it to the ones posting about the company lying and committing fraudery. I shouldve used a better choice of words rather than guilty but I agree entirely on everything you had said.
I understand that people have different opinions about Polarity and no one shouldve expected perfection, but their reasoning is comparable to that of a 5th grader. They arent going to discuss the science behind their 3D Platform for the reason given: its irrelevant?
It would be nice if this worked, but if they have been adding sugar to their product to cover false claims, then yea of course I and anyone else would hope their whole company fails for falsifying information. Not that it really matters to me anymore anyway since Ive been too busy to keep up with the forum.
11 hours ago, agelessfrost said:I may have missed out on your earlier post. I may be able to help (as long as it doesn't disclose my information) and maybe some funding.
Appreciate that. I wouldnt need any funding unless he for some reason asked me to design their whole site for them.
No personal information required.
I should be able to send him the sample page by the end of tomorrow. I had some bugs that I fixed and was working on responsive design so it could be viewable comfortably for mobile devices.
Ill message you regardless of his response
On 7/5/2018 at 4:09 AM, nikkigirl said:Because since this thread has been going on for over 10 years....nothing has been found. I don't think a human and a cat will ever mate either. Sure anything is possible but the odds are against it. There is a lot of things humans will never accomplish. To say that scarless healing will someday be possible and it can take only 10 years is purely speculation. The world might not be around in 10 years....maybe the sun will flare up and destroy life as we know it.....purely speculation.....nobody will know until it happens.
We have scarless healing genes in our bodies, it is just hidden inside waiting to unleash with the right factors. I don't see how this can be compared to human and cat mating. By the way, a lot of things can happen in a short time. Just 100 years ago, people still rode on horses for transportation, planes were still rudimentary. Now we have millions of people travelling by flight everyday. Television did not exist. Internet, smartphones did not exist too. Heck we did not even have those until much recently but we can't imagine life without them.
Even in a span of my short lifetime, I've seen lots of changes. People used bloody pagers in my childhood, now it just sounds hilarious. Videos games were pixels back when I was very young, now we have almost lifelike looking graphics and VR. It is not out of the realm of speculation to see say scarless healing is achievable when we are in an era of rapidly improving tech.
Although when it would happen is another story. It could be 100 years later ,Its still a very short timeframe compared to the length of humans existence, but we would not live to see it. Or it could be very very soon, like anytime now. We have no clue, but of course I hope for the latter.
œAusome's infection could have been caused by a number of things. A number of things we can't know 
Uhu right...Number 1, Number 2, Number 3: there is a wide open wound for weeks and months with a bloody gooey medium prime for pathogen growth! Do you think they are going to tell you the horror stories in their presentations?! How many more have had problems and failures?!
Bloody pointless thread. Better off closed than forever going back and forth with la la land inhabitants that just want to take us back to SkinTE and deny realities no matter what evidence and common sense there is. The point of a thread is to absorb new facts so a discussion can evolve and moves on to other steps. Not to keep beating up a dead horse and keep telling a lie in a fantasy bubble until it comes alive! That™s not called "hope"¦that™s self-deception and other kinds of deception, and impediment of progress and moving on.
The only thing subjective about SkinTE results is how horrible each result looks! Scarless healing and non-noticeable damage is NOT subjective there.
There should be no more waste of time about the failed SkinTE œregenerative œbetter-than-scar (forget about scarless) healing. Come back another year if you think you™ll have different news when the results turn miraculously less disastrous and not many patients have had more of their skin scraped off due to infection! And, update us if they have bribed enough people to turn their finally-rejected patent non-rejected in order to develop any more products. And if you can show where the plan is for making imaginary derivatives.
If you think you know more about business write your love letters to Polarity™s troubled team and offer them to help their legal defense. We do not have any reason or motivation to hear about excuses for SkinTE here! In the meanwhile you can move to private message, Polarity stock board, Polarity fantasy page, your mother™s bed, or an actual kindergarten (saying it nicely)¦
If I too don™t act like a lunatic who is about to commit suicide if you don™t tell me SkinTE is going to give me normal skin, and can laugh, it doesn™t mean I don™t have my own feelings and problems. So, stop using your fake childish œhope and pain as a weapon to excuse your trolling and craziness. We™re not your nurse or mama.
On 7/4/2018 at 2:57 PM, MyBeautifulScars said:@surgicalscarSome people here don't see SkinTE is a scam. Don't bother changing their point of view.
Yeah, they can live in their own dreams, but not dominate the thread and stop any sanity/facts from getting into it while disrupting intelligent conversations¦
@Candy Says take your filthy œhope trolling, and you know what you can do with it¦I™ve heard you have a special relationship with¦
10 hours ago, AI3forever said:Any reason why they are not going through human trials? Not enough funding? I messaged Sunogel about using it to treat acne scars awhile ago. They said its one of their goals, no timeframe or how they are going to achieve it though.
Money. At least that™s what it™s said about Sunogel. It's frustrating.
so surgical scar knows better than Denver lough...
The complete healed pics of wounds still havent shown
wait it gonna take time for a wound to completely heal and how it gonna look cosmetically....
the day they release full healed pics and you still find scar in full healed pics ..that day you can call skinTe a fraud
and another point you are comparing acne scar with a 3rd degree burn
acne scar treated by subcision can you treat a 3rd degree contracture scar with subcision ...dont compare both they are different maybe the pics we have seen had MUSCLE damage
and muscle regenration is in polarityTe pipeline as MyoTe ...so how can skinTe regenrate Muscle....stay positive
Parts of the Skinte application broke down from what they believe to be an old infection that they thought they had dealt with but obviously was still there and infected parts of the skinte site. I believe his whole arms were covered with skinte but only patches are being removed and replaced with older methods.
What i find interesting in that is why not take another skinte biopsy? it would be cheaper and less surgery. They therfore must suspect something to do with skinte partial failure and arent taking the risk with him.
Although i dont agree with @surgical scarapproach to this conversation sometimes lol he? Is right that for acne scars at this point in time its a dream. Its not even a garentee in 3rd degree burns eg their target market.
Im going to start researching again and come back with new material. Skinte is getting just arguementative rather than educational now.
4 hours ago, HandyDonjon said:FS2 completely regenerate the skin on the experiments?
Or just minimize scars?
It prevents scarring in fresh wounds but breaks down scar tissue on existing scars. One could imagine that you can excise existing scars, apply FS2 on it and the skin will heal with no scarring.
Yes, that's how I've understood it as well. That FS2 is supposed to prevent the formation of fibrous tissue and thus enable our skin to regenerate normally.
I thought at some point it was only for hypertrophic scars but then someone mentioned that the guy called Ryan from Birch biomed that created FS2 said it was for all scar types.
1 hour ago, Lapis lazuli said:Yes, that's how I've understood it as well. That FS2 is supposed to prevent the formation of fibrous tissue and thus enable our skin to regenerate normally.I thought at some point it was only for hypertrophic scars but then someone mentioned that the guy called Ryan from Birch biomed that created FS2 said it was for all scar types.
its a drug...it will take years to come
24 minutes ago, Anish004 said:its a drug...it will take years to come
Ryan spoke of that in an interview where he mentioned it wasn't yet known how it would be classified. If it's been classified by now officially as a drug then yeah, it's gonna take some time.
6 hours ago, Lapis lazuli said:Ryan spoke of that in an interview where he mentioned it wasn't yet known how it would be classified. If it's been classified by now officially as a drug then yeah, it's gonna take some time.
It's a drug. It's a cream or gel that you apply on a fresh wound like Mederma. They also have made pills of It that you can take orally. It will take a lot of time to be available because it is currently in phase 2 of clinical trials. Also, it prevents type 1 diabetes.
They claim they found a molecule that stops the overexpression of collagen buildup when in the healing phase. That is what FS2 contains.
There was an article that was published about phase 1 results in the Journal of Pharmaceutical Sciences. I am trying to find a copy of it.
I am in no way being a poster boy of this product.
I am posting things on here from my personal research.