Acne.org Products
On 24/05/2018 at 6:43 AM, Sniffy said:Hopefully you dont have to fly to America. They are in talks with major Biopharma companies now about possible distribution of Skinte Internationally which makes sense. At least for elective treatments like acne scars it makes sense to send them your biopsy and then have them send back your Skinte kit to country you live in. Any treating doctor can use the kit thats why they designed the real time app for doctors using Skinte.Unless they are looking at labs to process skinte in other coutries or they will just process everything from Utah.
yes you are likely right. Some of the best burn surgeons are in USA and Canada, UK and Australia because native doctors to countries such as pakistan come and work here for the NHS to better their training. They are trying to put in place a 'call of duty' for these doctors to donate some practice to their countries as their university was paid for by the state. Watched a thing last night with Dr Ali Jawad who is a burn surgeon help acid attack victimes back in Pakistan. Man those people need Skinte but i fear they wont have the expertise of Surgeons to help them.
Anyways. Yes i want to see some results on non burn scar revision first before i jump in. As we are not 'in need' with lack of skin or function to risk it looking worse. I emailed Sunogel to give them a poke lol common Dr Sun acne.org loves you!
On 5/23/2018 at 4:51 PM, nikki_gargin said:im interested for an insicion scar so would be all 3 layers effected for sure. I read somewhere the hypodermis does not renew as part of skin shedding renewal. I think this is done within the epidermal junction with the dermis if i read it right.
I try really hard not to get desperate but i feel the technology is so close thats its a realistic goal in the next 10 years. People can get their faces replaced now. I mean...imagine that idea 20 yea4s ago? ....sigh.
Tano, do you plan to speak with Swanson again?
Yes the epidermis does shed and regenerate itself every so often and it is the only layer that can. Most people would think that because of that ability, the skin regenerates from the outside in, but that wouldn™t be true. The epidermis does regenerate itself yes, but the dermis actually contributes to epidermal regeneration.
In short, if you had an injury extending into the dermis then the epidermal layer can not regenerate until the dermis re-establishes itself and its network of blood vessels otherwise it impedes proper epidermal establishment. Pretty much it throws the epidermis out of its neat and formal regenerative pattern and creates an abnormal repair.
As you can see the epidermis has layers within it as well and upon injury, the stratum basale which is the bottom layer of the epidermis, would regenerate first and then contribute to filling up from the bottom up through all layers. Even with no injury and just natural shedding, the bottom layers contribute to regenerating a new top layer when the uppermost layer is shed.
So although the hypodermis doesn™t go through some natural shedding process and doesn™t regenerate itself upon injury same with the dermis, it does contribute to dermal regeneration through a wnt pathway that can be manually directed to form adipocytes and adipose fat and then follicles (already studied by researchers) which are right directly above it to provide a proper dermal regeneration and in turn a proper dermal regeneration would contribute to a proper epidermal regeneration. Start from the bottom of an injury and move up.
I dont have any plans to contact Swanson right now. There™s no point until we get the final results. They are doing well with gaining popularity and acceptance from both the providers and patients.
In my call with him, he said they were only focused on a nationwide rollout and said international expansion would probably not be for awhile if at all. Fast forward to present day and here they are not even in 1/4th of burn centers in the country yet and the latest news was them discussing international availability. So I™d say they™ve been doing quite well so far. We™re more concerned with a cosmetic result though so we™ll see how that turns out.
1 hour ago, Anish004 said:hey they say reduced scar formation...first they said complete skin regeneration...
This has already been discussed before. There have been many terms used from Reduced, Scarless, Complete Regeneration, Full thickness skin, Far less Scarring......
keep in mind some of these descriptions were used before human trials. Most recent they have been saying "grown full thickness skin" and the young guys mother described it as "far less scarring" so make what you will of that. We have already heard of sweat glands and hair growth from deep wounds so there are definitely some positives without seeing finals results yet or use on small defects that are more relevant to us.
8 hours ago, Anish004 said:hey they say reduced scar formation...first they said complete skin regeneration...
As Sniffy stated, this has been discussed before several times.
The term "reduced scar formation" has been used throughout by PolarityTE. Why? Because SkinTE had a margin (which is scar tissue) in their preclinical results. It was too small to see with the naked eye but it was there, meaning they can't claim it's completely scarless.
Some might find that margin troubling, but as long as it's too small to see and the regenerated skin looks like normal skin, I don't think any of us will really care.
9 hours ago, golfpanther said:As Sniffy stated, this has been discussed before several times.The term "reduced scar formation" has been used throughout by PolarityTE. Why? Because SkinTE had a margin (which is scar tissue) in their preclinical results. It was too small to see with the naked eye but it was there, meaning they can't claim it's completely scarless.
Some might find that margin troubling, but as long as it's too small to see and the regenerated skin looks like normal skin, I don't think any of us will really care.
i know this is hard to answer right now but if anybody know than answer
the margin is from all side means suppose a circular wound regenerated using skinTe that to whole circumference therese is a margin ??
or just on one side ?
44 minutes ago, Anish004 said:i know this is hard to answer right now but if anybody know than answer
the margin is from all side means suppose a circular wound regenerated using skinTe that to whole circumference therese is a margin ??
or just on one side ?
The margin is where the normal skin meets with the excision wherein SkinTE was placed. So, the entire circumference of a circular wound would have the margin if human results are the same as preclinical ones.
1 hour ago, agelessfrost said:Wow SkinTE truly sounds like the holy grail. Is there any way a normal person can take part in its clinical trial? I have severe stretch marks on 70% of my body - and it's at the point where I can't even wear a bra or a belt without bleeding....
you cant take part in clinical trial nobody knows where thats taking place
polarityTe said they will release pics from human trials in 1st half of 2018 and 1st half of 2018 is just on end 1 month away...
we will see pics anytime..
if they believe in luck then i think they release pics on 8 june ..coz complete 1 year back on 8 june 2017 they released preclinical results(lol its just a assumption)
18 hours ago, agelessfrost said:Wow SkinTE truly sounds like the holy grail. Is there any way a normal person can take part in its clinical trial? I have severe stretch marks on 70% of my body - and it's at the point where I can't even wear a bra or a belt without bleeding....
Sorry to hear about your condition.
As Anish stated, at this point the trial participants have already been chosen. Plus, since SkinTE went straight to market without first getting FDA approval, it's not operating like most trials where it would be posted on clinicaltrials.gov.
Mid to late stage healing results should be coming soon so we'll all know how well it worked for burns. If what was posted on the Facebook page about the young man's recovery using SkinTE holds (i.e. burn down to the bone that is now regenerating sweat glands and hair follicles) then I think we'll all be very optimistic about future cosmetic applications.
If nothing comes before this, you can bet new images and results will be presented here:
On 29/05/2018 at 6:33 PM, golfpanther said:If nothing comes before this, you can bet new images and results will be presented here:
yes definately! They have another conference thing on 7th or 8th June so that might have extra pics uploaded as well. It will be 6th month so end of June is 1st half gone of this year.
22 hours ago, golfpanther said:None of us can give you that answer, Rudy. I think it will be an improvement over skin grafts at least, but beyond that it's just guessing.
Depending upon the viscosity of the paste my guess is it can be used as a filler similar to fat grafting.
1 hour ago, AI3forever said:I am wondering, how do they stop the paste from falling off your face when they apply it to your excised skin?
Pretty sure this was covered in Tano's post, but it's an adhesive bandage that is placed over the site. I think it creates a water barrier of some kind too in order to keep the wound bed moist.
On 5/24/2018 at 4:04 PM, SimpleMutton said:I remember last year we were saying the same things
They have to make an announcement about possibility to use SkinTE even for acne scars.
I'd do it immediately, it's on my back and really need that. My life is shit because of scars
Im same boat with you my life is totally devastated from scars.
On 01/06/2018 at 11:18 PM, Binga said:On 01/06/2018 at 1:06 AM, golfpanther said:None of us can give you that answer, Rudy. I think it will be an improvement over skin grafts at least, but beyond that it's just guessing.Depending upon the viscosity of the paste my guess is it can be used as a filler similar to fat grafting.
Im not sure just injecting it will work wonders unless it really does propagate into scar tissue, time will tell if it does this like it showed in Pigs.
The unknown for smaller scars that are not so deep is Whether scar tissue needs to be completely removed first or it can just be disrupted to create a wound bed to trigger new healing with SkinTe introduced. The latter is a far more appropriate approach to acne scars.
It will be interesting to see the 10 year old boys final results after he had only top layers of scarred skin removed. How much does it improve the look of the skin both contraction and texture with deeper fibrotic scar tissue still sitting under his new SkinTe
i need some motivation can i ask that everybody here
what types and how severe scarring you are suffering from ?
and carrying these scars u all had been able to live your life till now so
whats your current stage means a student or have a job or a worker
sorry for my bad eng...it isnt my native language
but reply please
student age 23, scars since 2014. they are sever probably a 8. mostly boxcar and rolling. This year i have had several tx including infini rf, and will be getting successions plus fillers. it has a affected me pretty bad but i hope this year i can soften the scars out a bit.