Acne.org Products
1 hour ago, golfpanther said:That would be ideal. Even though my scars aren't from acne, I feel your pain.Let's all keep an eye on PolarityTE and Sunogel and hold them to their burden.
I don't mind the childhood scars I got from accidents through cuts or scrapes. Everybody has them. Recently, I got another one from a drinking glass that broke.
I must say one stupid car accident in my teenager years left me with a dozen scars all over. They make another good story to tell.
I have also some other scars from other incidents which taught me some valuable life lessons.
What I do mind though is for my facial craters and white scars covering my back and shoulders to go. It would be such a relief to finally beat acne and get rid of the trades it left behind.
I hope SkinTE and Sunogel will be the first approaches to eliminate disfigurement but I believe we are still a few years before all this becomes reality.
1 hour ago, Anonymouz1 said:I don't mind the childhood scars I got from accidents through cuts or scrapes. Everybody has them. Recently, I got another one from a drinking glass that broke.I must say one stupid car accident in my teenager years left me with a dozen scars all over. They make another good story to tell.
I have also some other scars from other incidents which taught me some valuable life lessons.
What I do mind though is for my facial craters and white scars covering my back and shoulders to go. It would be such a relief to finally beat acne and get rid of the trades it left behind.
I hope SkinTE and Sunogel will be the first approaches to eliminate disfigurement but I believe we are still a few years before all this becomes reality.
bro ..if you have scars from car accident on your face than they are really bad..but if is on another body part then its not a matter...face scars are always main priority to everyone
sry for my bad eng
Regarding hyperpigmention how will we know if the new regenerated skin will not develop hyperpigmention as a result of the trauma?
If acne scarring is not very deep in terms of contour and the main issue was mostly texture would there be no margin to worry about if the damaged texture was dermasanded/dermabrasion down? Im aware margin is not a major concern given they say you would need a microscope to see it
Also what about redness be it broken capillaries under the skin from past trauma like a background redness, does Skinte and/or Sunogel reorganize blood vessels within the skin or under?
skinte sounds very promising and news of them moving into this huge facility is very positive. They wouldnt make such a move unless they knew what this product was going to do, i think thry know exactly what it can achieve and they have talked the talk and now they are ready to walk the walk. They have been bullish about their product from day dot so fingers crossed its a game changer.
On 12/23/2017 at 9:26 AM, kim6288 said:On 12/22/2017 at 10:20 PM, rudy1986 said:how do we get into one of the places that is using this now on scar revisions
My guess is you have to be in an emergency room somewhere with severe burns. This is how they decided to proceed. They are US based, so also you must be in the US.
Also what if this fails and you get a worse disfigurement than before.
4 hours ago, Anonymouz1 said:My guess is you have to be in an emergency room somewhere with severe burns. This is how they decided to proceed. They are US based, so also you must be in the US.Also what if this fails and you get a worse disfigurement than before.
As stated in their press release, it's not only being used for burns but also a wide variety of skin issues.
An easy guess would be it's at Johns Hopkins, given the founders connection to the university and that of their chief clinical officer. Outside of that, it's probably at prestigious burn and plastic surgery centers in the US. I think Swanson mentioned that there are 126 burn centers in America. I mean, you could technically just try calling all of them and find out.
7 hours ago, golfpanther said:As stated in their press release, it's not only being used for burns but also a wide variety of skin issues.An easy guess would be it's at Johns Hopkins, given the founders connection to the university and that of their chief clinical officer. Outside of that, it's probably at prestigious burn and plastic surgery centers in the US. I think Swanson mentioned that there are 126 burn centers in America. I mean, you could technically just try calling all of them and find out.
in press release there is word "scar revison" which totally means treatment of preexisting scars.mso i assume that they are planning into cosmetic market also and not only burn patients
however yes burn or acid attack victims should always be given first priority.
8 hours ago, DinkumFridge said:
good article, we'll know in a couple of months if this is THE CURE (and not just some random stupid improvement) or it's another failure
20 hours ago, Anish004 said:in press release there is word "scar revison" which totally means treatment of preexisting scars.mso i assume that they are planning into cosmetic market also and not only burn patients
however yes burn or acid attack victims should always be given first priority.
If you look back a bit on this thread you will see I posted an interview I did with Swanson from PolarityTE. He told me at the time (2 days before the press release) that SkinTE was being used for a variety of wound types.
In terms of contacting the burn centers, that was merely a jumping off point if you were inclined to take up the effort to find where SkinTE currently is being used. I'm not encouraging anyone to do that, but it's an option if someone wanted.
3 hours ago, SimpleMutton said:12 hours ago, DinkumFridge said:good article, we'll know in a couple of months if this is THE CURE (and not just some random stupid improvement) or it's another failure
Even if it's an improvement and not 100% scarless healing, I still believe its an improvement nonetheless. These guys were innovative and probably are pushing others to truly come up with a scarless healing method.
If you get 95% improvement on those acne scars, a lot of people with disfigurement will go through this to achieve a somewhat normal appearance. Let's face it fillers, dermabrasion, skin needling and laser resurfacing will never get you 95% improvement.
On 12/16/2017 at 11:41 PM, golfpanther said:This picture from their site explains it:
As you can see, it's applied to a wound. So, if you want to get rid of an existing scar you would need to excise it to create a wound bed for the hydrogel to be put into.
Sunogel was formed in 2015, but their paper detailing how they achieved complete regeneration in pigs using Dr. Sung's new DexIEME. To clarify, Sun used to work at Dr. Sharon Gerecht's lab at Johns Hopkins where they created the original dextran hydrogel (DexAE) that went on to be patented and used as the main piece of technology when Gemstone Biotherapeutics was formed. Sun's new hydrogel (DexIEME) is different the one that got "perfect skin" (pully directly from the paper) in pigs.
Here's a link to the paper. It's free to read right now since it was one of the most read papers in the last few months:
http://onlinelibrary.wiley.com/doi/10.1002/adhm.201700659/full
Whatever happened to Gemstone's hydrogen?
25 minutes ago, Anonymouz1 said:Even if it's an improvement and not 100% scarless healing, I still believe its an improvement nonetheless. These guys were innovative and probably are pushing others to truly come up with a scarless healing method.If you get 95% improvement on those acne scars, a lot of people with disfigurement will go through this to achieve a somewhat normal appearance. Let's face it fillers, dermabrasion, skin needling and laser resurfacing will never get you 95% improvement. Whatever happened to Gemstone's hydrogen?
Their hydrogel, the DexAE version, didn't give the same results in pigs as it did in mice. I'm assuming they're still moving forward in some regards but as of now it looks like a dead end in terms of complete regeneration.
One thing that worries me about Sunogel is that while Sun's version of the hydrogel got perfect skin in pigs, it's undoubtedly derived from the research done while he was at JHU with Gerecht. That could become problematic because that hydrogel is patented. It's one of things I want to bring up when I talk to him.
24 minutes ago, golfpanther said:Their hydrogel, the DexAE version, didn't give the same results in pigs as it did in mice. I'm assuming they're still moving forward in some regards but as of now it looks like a dead end in terms of complete regeneration.One thing that worries me about Sunogel is that while Sun's version of the hydrogel got perfect skin in pigs, it's undoubtedly derived from the research done while he was at JHU with Gerecht. That could become problematic because that hydrogel is patented. It's one of things I want to bring up when I talk to him.
From my understanding then, apart from SkinTE and Sunogel, we really don't have at the moment, any other leads.
I hope SkinTE proves to be succesful.
Also as you mentioned, Cotsarelis' research is just in the preliminary phase.
On 12/24/2017 at 10:35 AM, Anonymouz1 said:My guess is you have to be in an emergency room somewhere with severe burns. This is how they decided to proceed. They are US based, so also you must be in the US.Also what if this fails and you get a worse disfigurement than before.
that is not going to happen dude seriously. I live in the U.S. in driving distance to John Hopkins. It would be a Christmas miracle if they could help me
19 hours ago, golfpanther said:If you look back a bit on this thread you will see I posted an interview I did with Swanson from PolarityTE. He told me at the time (2 days before the press release) that SkinTE was being used for a variety of wound types.In terms of contacting the burn centers, that was merely a jumping off point if you were inclined to take up the effort to find where SkinTE currently is being used. I'm not encouraging anyone to do that, but it's an option if someone wanted.
I think its at John Hopkins maybe I will get to go there and fix my problem
26 minutes ago, kim6288 said:that is not going to happen dude seriously. It will be either completely healed or you won't be able to see it. and I do live in the US. how did you get to talk to this guy? Can you find out from him what states it is being used? I guess Utah where the headquarters is located?
I simply reached out to him via their website. I was quite surprised that they were willing to talk to me as well. Our convo was pretty much everything that was covered in the press release, plus some other information I posted on here.
In terms of it failing and getting worse disfigurement than before, I agree, that's unlikely to happen. My guess is that they are first using SkinTE on smaller areas of skin, even in burn victims. So instead of removing entire sections of skin grafts to apply SkinTE, they're probably removing a small portion to see what results they get. If it proves to work like it did in pigs then they'll do the rest.
On Polarity's facebook page it is all about burn victims. If it does show
improvement on acne scars it will still take time to train plastic surgeons and derms. I hope it does work because it will help out a lot of acne scar people....mentally mostly. Just be ready for the let down in case it doesn't work. I am personally waiting a few years until i know this treatment works long term on patients before i put money into it.
47 minutes ago, nikkigirl said:On Polarity's facebook page it is all about burn victims. If it does show
improvement on acne scars it will still take time to train plastic surgeons and derms. I hope it does work because it will help out a lot of acne scar people....mentally mostly. Just be ready for the let down in case it doesn't work. I am personally waiting a few years until i know this treatment works long term on patients before i put money into it.
lol train for what? they just have to make an excision, they already know how to do it
1 hour ago, nikkigirl said:On Polarity's facebook page it is all about burn victims. If it does show
improvement on acne scars it will still take time to train plastic surgeons and derms. I hope it does work because it will help out a lot of acne scar people....mentally mostly. Just be ready for the let down in case it doesn't work. I am personally waiting a few years until i know this treatment works long term on patients before i put money into it.
You will know well before a few years if it works. The product is on patients as we type on this board and data will be released over the first half of 2018. Either way, you'll have your answer very soon.
On 12/24/2017 at 2:56 PM, golfpanther said:As stated in their press release, it's not only being used for burns but also a wide variety of skin issues.An easy guess would be it's at Johns Hopkins, given the founders connection to the university and that of their chief clinical officer. Outside of that, it's probably at prestigious burn and plastic surgery centers in the US. I think Swanson mentioned that there are 126 burn centers in America. I mean, you could technically just try calling all of them and find out.
Thank you ! yes maybe at John Hopkins! I just called there to find out