On 15/08/2017 at 1:36 AM, ObservantJeep said:

http://business.nasdaq.com/discover/market-bell-ceremonies/detail.html#!/!?ceremonyId=7740

The hype is real.

polarity looks confident in them onhuman trials with Their big smile

The chip technology looks incredible, unfortunately I'm getting behind on these new treatments and don't know which ones to put stock (belief) in.

I am still wondering about FS2. Remember we got an e-mail saying that it completely prevented scars in the phase 1 human trial? There are only 2 phases to go, so I wonder why we haven't heard more about it. Would someone be able to contact them and ask?

20 minutes ago, scarred2468 said:

The chip technology looks incredible, unfortunately I'm getting behind on these new treatments and don't know which ones to put stock (belief) in.

I am still wondering about FS2. Remember we got an e-mail saying that it completely prevented scars in the phase 1 human trial? There are only 2 phases to go, so I wonder why we haven't heard more about it. Would someone be able to contact them and ask?

FS2 did state this but the approval process would take much longer than Polarity. Basically, if Polarity works it will make FS2 Irrelevant.

1 hour ago, scarred2468 said:

The chip technology looks incredible, unfortunately I'm getting behind on these new treatments and don't know which ones to put stock (belief) in.

I am still wondering about FS2. Remember we got an e-mail saying that it completely prevented scars in the phase 1 human trial? There are only 2 phases to go, so I wonder why we haven't heard more about it. Would someone be able to contact them and ask?

Is FS2 a drug ? what is progress of its trial ?

For me, only the complete regeneration of the skin, could delete a scar. I do not believe it in drug, cream ... At present, I think that our biggest hope it is polarity

3 hours ago, scarred2468 said:

The chip technology looks incredible, unfortunately I'm getting behind on these new treatments and don't know which ones to put stock (belief) in.

I am still wondering about FS2. Remember we got an e-mail saying that it completely prevented scars in the phase 1 human trial? There are only 2 phases to go, so I wonder why we haven't heard more about it. Would someone be able to contact them and ask?

Because it does not work, so far they have not provided any results that show that it can prevent and regenerate skin. They have only done phase 1 testing which is a safety test without wounding to see if it has any allergic or other side effect. Furthermore more I don't believe FS2 will works, because a lot of companies who tried it with a single molecule/ cell/ hormone etc badly failed in the past!!! For example Renovo, Ohh we will increase one of the TGF's and scars will be prevented, and they failed! Because skin regeneration is more than just preventing collagen bundles, research from various groups has shown that all the cells in the skin are linked with each other and leaving out one or just applying one will not regenerate skin. For example - Cotsarelis lab could prove that first new hair follicle has to be formed in order to turn the scar forming myofibroblast into fat cells instead of a scar. And in order to regenerate skin to cosmetically the point that you cannot see the scar, i will require all the appendixes only then it can blend in with the surrounding.

7 hours ago, damnBOY said:

look these veins they are superficial veins if polarityte cut the damaged skin both dermis and hypodermis can someone tell me how they will regenerate these veins? these veins are located to hypodermis... if they remove hypodermis they remove these veins a how the hell they will regenerate them ?

Again, those veins and main blood lines are below the skin, and will not be affected, only small bloodlines to supply supplements are in the skin and they get formed automatically. Even scar tissue has connecting blood lines otherwise skin would die off. And regarding stretchmarks I don't think it will be required to cut it out since it's not exactly a fibrotic scar it's that the dermis is super thinned out and the missing appendixes need to be regenerated. So I think Microneedling + Skinte or direct grafting of SkinTE by injections into the stretchmarks (the same way as Tropoelastin would be applied and how currently fat grafting is done). Also polarity uses the phrase application into burns, wounds and scars will result in complete regeneration, if cutting out would be required they would certainly not use the word into scar, they would just say into wounds. Apart from that they also stated the option of grafting / transplanting by injections in their patents. So I am sure that for stretchmarks and minor scars a less invasive way will be applicable 

If we succeed in regenerating the skin with all its appendixes, we would thus have a chance thatscars( atrophic... )Disappear to 100%. Correctme, if I'm wrong sunnyx

Fascinating research

http://www.medicalnewstoday.com/articles/318949.php

any connection of this to scars ?

14 minutes ago, Binga said:

Fascinating research

http://www.medicalnewstoday.com/articles/318949.php

.

On 8/7/2017 at 10:27 AM, Anish004 said:

which scar you are seeing  i am talking about that on up my nose below my eyebrow

MAN UP you mother boy is only a invisible small scar you dont have nothing. My scars are 1000% worse than yours, I have very bad scars in face and shoulders from severe acne.

sorry for my eng.

40 minutes ago, Albaneso said:

MAN UP you mother boy is only a invisible small scar you dont have nothing. My scars are 1000% worse than yours, I have very bad scars in face and shoulders from severe acne.

sorry for my eng.

I agree, I have small burns, most of you are worried about the most trivial stuff. He is worried about a little tiny dot that nobody sees. Good lord.

On 8/15/2017 at 7:16 AM, Anish004 said:

what about this

http://labiotech.eu/uc3-biodan-3d-printed-human-skin/

I see you've been asking about everything. You've got to relax and do some of the research on your own. Nobody will answer everything for you.

I'll answer this one because this was already mentioned by me. Bioprinted skin is a reality and it can replace animal testing to provide more accurate drugs/cosmetics. They use hydrogels and construct the skin through many layers that then connects to each other.

This actually does have implications that it could end scars, but it has yet to be tested on humans. It does take human's cells to build the construct, but there are also external factors that come into play thus requiring FDA phase trials. I believe (don't quote me) they may be able to skip phase 3 trials using this method, but must undergo at least a safety and efficacy trial. In other words: it would take several years even if they started right now.

Bioprinting also, just like PolarityTE, has potential to give birth to the Era of regeneration. It's a race to the finish line, and PolarityTE may take the skin market entirely.

Do some of the research and you'll find lots of useful information that will allow you to raise some good questions. You need to understand how everything works first and even look up some of the medical terms you don't understand.

On 8/9/2017 at 6:57 AM, damnBOY said:

-skinTE has regenerated full thickness fractional skin in swine models, because the skin of pigs is similar to ours it is certain that will work for humans as well
-polarityte hasannounced: if they successfull on the burn Market they will explore entryinto other markets like hair regeneration ,cosmetic/scar revision (they say skinte doesnt only work for wounds and burns but it propagates into old scar tissue and regenerate full fractional skin
-the clinical trials has already started for burnsat july and they will last for 3 months , i dont know howyou can become part of them.
-yes SALT LAKE CITY
, SORRY FOR MY SIMPLICITY OF MY english, enlgishis not my native language

check their Facebook /Twitter and website

Thank you for answering my questions! I don't understand why all of these skin companies are initially aiming toward burn scars. You would think they would simultaneously start trials on all different types of scars..

1 hour ago, CollegeKidd said:

On 9.8.2017 at 0:57 PM, damnBOY said:

-skinTE has regenerated full thickness fractional skin in swine models, because the skin of pigs is similar to ours it is certain that will work for humans as well
-polarityte hasannounced: if they successfull on the burn Market they will explore entryinto other markets like hair regeneration ,cosmetic/scar revision (they say skinte doesnt only work for wounds and burns but it propagates into old scar tissue and regenerate full fractional skin
-the clinical trials has already started for burnsat july and they will last for 3 months , i dont know howyou can become part of them.
-yes SALT LAKE CITY
, SORRY FOR MY SIMPLICITY OF MY english, enlgishis not my native language

check their Facebook /Twitter and website

Thank you for answering my questions! I don't understand why all of these skin companies are initially aiming toward burn scars. You would think they would simultaneously start trials on all different types of scars..

One more time, they designed the product at the first place to treat burns and wound and yes they can treat scars but this is often not their main objective; Burns from Fire, chemicals and acids are worst injuries which often lead to death due to loss of large areas of tissue and if you survive often people are not able to move their arms, legs due to contractual scars, leave alone the massive diformation. So if skin after burns can be regenerated, then it can be applied to anything else. Second point is that of getting clearance, currently there is no treatment for 3rd degree burns therefore approval by regulators is easier since possible side effects are considered as less weighted compared to death. Third point is that of limited resources; trials are costly and time consuming; so it makes common sense to go for the worst injury and have a trial there, instead of waisting resources on minor issues compared to burn victims. Fourth point is how quickly doctors are about to adopt a new technology. For a cosmetic scar issue no doctor would take the risk of a new technology, however in severe burns they have currently no good product, therefore the risk of anything vs. death is more acceptable and therefore the chance higher that the technology will be Applied more willingly. From burns centers it will move to cosmetic surgeons.

9 hours ago, Albaneso said:

MAN UP you mother boy is only a invisible small scar you dont have nothing. My scars are 1000% worse than yours, I have very bad scars in face and shoulders from severe acne.

sorry for my eng.

bro i dont have that just small scar but also large moles on cheeks and acne scars on side of my cheeks.

7 hours ago, Tano1 said:

I see you've been asking about everything. You've got to relax and do some of the research on your own. Nobody will answer everything for you.

I'll answer this one because this was already mentioned by me. Bioprinted skin is a reality and it can replace animal testing to provide more accurate drugs/cosmetics. They use hydrogels and construct the skin through many layers that then connects to each other.

This actually does have implications that it could end scars, but it has yet to be tested on humans. It does take human's cells to build the construct, but there are also external factors that come into play thus requiring FDA phase trials. I believe (don't quote me) they may be able to skip phase 3 trials using this method, but must undergo at least a safety and efficacy trial. In other words: it would take several years even if they started right now.

Bioprinting also, just like PolarityTE, has potential to give birth to the Era of regeneration. It's a race to the finish line, and PolarityTE may take the skin market entirely.

Do some of the research and you'll find lots of useful information that will allow you to raise some good questions. You need to understand how everything works first and even look up some of the medical terms you don't understand.

the reason for asking i am suffering from many scars on my face and i always feel suicidial ...i just want anything that remove my scars completely...i know i became annoying member to everyone...but i am hopeless

14 minutes ago, Anish004 said:

bro i dont have that just small scar but also large moles on cheeks and acne scars on side of my cheeks.

honestly i dont care about this scar which i show in picture but this scar captured in good quality so i asking just as a refferal to acne scars......i feel sad when people dont understand my problem

the reason for asking i am suffering from many scars on my face and i always feel suicidial ...i just want anything that remove my scars completely...i know i became annoying member to everyone...but i am hopeless

I'm going to give you an honest answer. There's not 1 thing that will completely remove a scar. Nothing at all. What we should be grateful for is that we have already witnessed a breakthrough where scarring can now be reversible. It used to be the idea that scars were permanent and they stuck with you for life. Now they believe it can be reversed and even eradicated. That's what I call Hope right here.

Your skin looks fine compared to a lot of other people's. I have a giant 7 inch long scar on my head that can't be hidden. If you want I'll trade you.

SkinTE is your ONLY potential option to get rid of your scars in the near future. If that doesn't work, at least you'll have current treatments that can reduce scarring. They've been on point with everything since they've started the company. Be patient and wait just a couple of months.

58 minutes ago, Tano1 said:

I'm going to give you an honest answer. There's not 1 thing that will completely remove a scar. Nothing at all. What we should be grateful for is that we have already witnessed a breakthrough where scarring can now be reversible. It used to be the idea that scars were permanent and they stuck with you for life. Now they believe it can be reversed and even eradicated. That's what I call Hope right here.

Your skin looks fine compared to a lot of other people's. I have a giant 7 inch long scar on my head that can't be hidden. If you want I'll trade you.

SkinTE is your ONLY potential option to get rid of your scars in the near future. If that doesn't work, at least you'll have current treatments that can reduce scarring. They've been on point with everything since they've started the company. Be patient and wait just a couple of months.

what we have to attain in scarless healing of any wound ...after that any scar excised and made wound and then scarless healing...hope PolarityTe do so ..

stay Positive anish004, others has worse,even if I understands you. Skinte could certainlyHealing your scarsor not. It is necessary to wait humans trials

On 8/15/2017 at 11:11 PM, mjg713 said:

On 8/15/2017 at 10:49 PM, scarred2468 said:

The chip technology looks incredible, unfortunately I'm getting behind on these new treatments and don't know which ones to put stock (belief) in.

I am still wondering about FS2. Remember we got an e-mail saying that it completely prevented scars in the phase 1 human trial? There are only 2 phases to go, so I wonder why we haven't heard more about it. Would someone be able to contact them and ask?

FS2 did state this but the approval process would take much longer than Polarity. Basically, if Polarity works it will make FS2 Irrelevant.

I suppose, however I'd like to see FS2 go through. It is extremely convenient to prevent scarring with a portable chemical, and I think it would allow for more specialized, customized and affordable scar management than repeated in-office procedures.

3 hours ago, Tano1 said:

I'm going to give you an honest answer. There's not 1 thing that will completely remove a scar. Nothing at all. What we should be grateful for is that we have already witnessed a breakthrough where scarring can now be reversible. It used to be the idea that scars were permanent and they stuck with you for life. Now they believe it can be reversed and even eradicated. That's what I call Hope right here.

Your skin looks fine compared to a lot of other people's. I have a giant 7 inch long scar on my head that can't be hidden. If you want I'll trade you.

SkinTE is your ONLY potential option to get rid of your scars in the near future. If that doesn't work, at least you'll have current treatments that can reduce scarring. They've been on point with everything since they've started the company. Be patient and wait just a couple of months.

tano1 say : "There's not 1 thing that will completely remove a scar. Nothing at all"
you think that skinte cannot delete a scar to 100% ? Nevertheless skinte regenerate completely the skin and appendices . Ifthey successful at regenerate a burn of the 3eme degree on humans, theycould regenerate completely the scars

2 hours ago, slave of jesus said:

tano1 say : "There's not 1 thing that will completely remove a scar. Nothing at all"
you think that skinte cannot delete a scar to 100% ? Nevertheless skinte regenerate completely the skin and appendices . Ifthey successful at regenerate a burn of the 3eme degree on humans, theycould regenerate completely the scars

Ah no don't misinterpret what I said. There isn't something currently in the present time that will completely remove a scar. You can only reduce scars at best for now.

SkinTE can definitely change that. It is true that even if they succeed they will take a couple more years to bring scar revisions to market, but we shouldn't be upset for that. The most important thing is succeeding. This would be like a cure for scars because 3rd degree burns are worse to put it shortly. Basically the biggest news we can receive is that it works for burns and they achieve damn near total regeneration. If that gets announced from these human trials like it did for swine then we will all pop open a champagne bottle and toast to us here on this forum.

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23 minutes ago, Tano1 said:

Ah no don't misinterpret what I said. There isn't something currently in the present time that will completely remove a scar. You can only reduce scars at best for now.

SkinTE can definitely change that. It is true that even if they succeed they will take a couple more years to bring scar revisions to market, but we shouldn't be upset for that. The most important thing is succeeding. This would be like a cure for scars because 3rd degree burns are worse to put it shortly. Basically the biggest news we can receive is that it works for burns and they achieve damn near total regeneration. If that gets announced from these human trials like it did for swine then we will all pop open a champagne bottle and toast to us here on this forum.

excuse me! I had badly understood. If skinte made a success.I would have liked that we meet all in reality to celebrate that. Unfortunately, we live not in all in the same country

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