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[Sticky] Scarless Healing

 
MemberMember
7
(@scarred2468)

Posted : 11/23/2016 11:32 am

Can you find where you read that from?

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MemberMember
7
(@scarred2468)

Posted : 11/27/2016 9:53 am

mjg, where did you read that from, that a dextran hydrogel would take one year? Anyone else there?

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0
(@Anonymous)

Posted : 11/27/2016 1:17 pm

Yeah, I was also under the assumption that a device could be ready in 1 to 2 years.

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MemberMember
36
(@mjg713)

Posted : 11/27/2016 2:47 pm

4 hours ago, scarred2468 said:

mjg, where did you read that from, that a dextran hydrogel would take one year? Anyone else there?

I can't find the direct source but i'm sure someone on here has it, it's in one of the Gemstone press releases I believe. If you want just look the FDA law up, it takes up to 1 year for devices. This IS how long hydrogel would take since it does not contain any drugs. Maybe a little longer before it reaches actual clinical use, but nothing near 8-10 years. Let's just hope it actually works! I want an update.

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MemberMember
48
(@ai3forever)

Posted : 11/28/2016 12:42 am

There is a surgeon who will do a complete head transplant for a patient next year but we don't have scarless healing?

I can't believe that scarless healing is harder to achieve that freaking taking a person's head and placing to another's body.

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MemberMember
24
(@jackdoe)

Posted : 11/28/2016 5:06 am

They don't take it seriously.If more scientists will be engaged in it seriously, we will get scar-free wound healing within 5 years.

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0
(@Anonymous)

Posted : 11/29/2016 12:52 am

19 hours ago, JackDoe said:

They don't take it seriously.If more scientists will be engaged in it seriously, we will get scar-free wound healing within 5 years.

I don't even think it's that people don't take it seriously. I think it's that people are led to believe that it's impossible, which is most likely untrue.

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MemberMember
7
(@scarred2468)

Posted : 11/29/2016 12:29 pm

Yeah, if you look at it as possible, which it certainly is, maybe you'll be more encouraged to crack it. Mjg the thing is a hydrogel might not be a drug but it is a chemical, I would really appreciate it if you could find the gemstone source saying it'd take a year.

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MemberMember
92
(@binga)

Posted : 11/29/2016 4:27 pm

Gemstone released a statement today that they are going to start human trials next year. Also their product is good for hair restoration.

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MemberMember
36
(@mjg713)

Posted : 11/29/2016 5:06 pm

38 minutes ago, Binga said:

Gemstone released a statement today that they are going to start human trials next year. Also their product is good for hair restoration also.

Where is this statement? I don't see anything on their website.

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MemberMember
68
(@rudy1986)

Posted : 11/29/2016 5:38 pm

Facebook

Btw they are pretty direct in stating hair follicle REGROWTH potential..

I mean, this is freakingly huge

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MemberMember
36
(@mjg713)

Posted : 11/29/2016 11:11 pm

5 hours ago, rudy1986 said:

Facebook

Btw they are pretty direct in stating hair follicle REGROWTH potential..

I mean, this is freakingly huge

Take this with a grain a salt. I remember reading about another gel that achieved hair regrowth but it was like very patchy spare hair growth and not your average hair growth. But I guess something is better than nothing.

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MemberMember
108
(@de-rerum-natura)

Posted : 11/30/2016 12:17 am

https://www.ncbi.nlm.nih.gov/pubmed/27665369

take a look at this article

" In this study, using loss- and gain-of-function rodent fetalwoundmodels, we identified that fibromodulin (Fm) is essential for fetal-typescarlesswound healing. In particular, we found that loss of Fm can eliminate the ability of early-gestation fetal rodents to heal without scar. Meanwhile, administration of fibromodulin protein (FM) alone was capable of restoringscarlesshealingin late-gestation rat fetal wounds, which naturally heal with scar, as characterized by dermal appendage restoration and organized collagen architectures that were virtually indistinguishable from those in age-matched unwounded skin".

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MemberMember
7
(@scarred2468)

Posted : 11/30/2016 11:30 am

Rudy, could you please inform us a little
more about sunogel, there's barely any info on the website. Does Dr. Sun have any sort of planned release or start date for clinical trials? Is it dextran based as well with nothing added to it?

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MemberMember
7
(@scarred2468)

Posted : 11/30/2016 3:25 pm

I called Gemstone to ask about what kind of trials the dextran scaffold will require. Left a message and hopefully they'll call me back soon.

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JackDoe, JackDoe and JackDoe reacted
MemberMember
68
(@rudy1986)

Posted : 11/30/2016 7:30 pm

I think sunogel is prepping for the clinical trial.. however, no timeline was ever mentioned to me..

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MemberMember
7
(@scarred2468)

Posted : 11/30/2016 11:18 pm

If the two hydrogels are similar, maybe it's possible that sunogel and gemstone are competing. I hope they both go at it quick. But we don't even know what sunogel's thing is or if it's any different from gemstone

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MemberMember
36
(@mjg713)

Posted : 11/30/2016 11:23 pm

5 minutes ago, scarred2468 said:

If the two hydrogels are similar, maybe it's possible that sunogel and gemstone are competing. I hope they both go at it quick. But we don't even know what sunogel's thing is or if it's any different from gemstone

Why are you so concerned about sunogel? seems like Gemstone is on track for clinical trials, and that is great news.

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MemberMember
36
(@mjg713)

Posted : 12/01/2016 3:14 pm

Hey guys, check this out: http://www.thehindu.com/sci-tech/health/Wild-silk-protein-helps-in-faster-scar-free-healing-of-wounds/article16737907.ece . Not sure about the source but it is interesting nonetheless. The protein fully regenerated full thickness wounds in rabbits with glands and hair growth. Seems like things are really starting to come together for scarless healing.

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0
(@Anonymous)

Posted : 12/01/2016 3:47 pm

I hope by "next year" they mean the beginning of next year, and not the end lol. If they started trials in the Winter or Spring I would be so happy.

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MemberMember
7
(@scarred2468)

Posted : 12/01/2016 8:30 pm

mjg,it's best to put some faith in as many people as we can, like the people in the article you linked. As long as there is a reason for believing they can accomplish what you're looking for. That's why I'm interested in sunogel, I want to put them on a list of potential future cures, but there's literally nothing concrete about them. You're bound to be disappointed if you think Gemstone or any one company can do it, because there will likely be numerous failures until it's done.

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MemberMember
378
(@rez77)

Posted : 12/03/2016 1:19 am

3 years away from human trials. The technology is not realizable yet though either which they don't directly
say in this article. I would say clinical application at your local cosmetic surgeon maybe 10-15 years? Maybe....

http://www.cbc.ca/news/technology/printalive-3d-skin-tissue-printer-wins-canadian-dyson-award-1.2770667

On 12/1/2016 at 3:47 PM, CollegeKidd said:

I hope by "next year" they mean the beginning of next year, and not the end lol. If they started trials in the Winter or Spring I would be so happy.

lol I guess that's the optimism of youth as you are truly a college kid. 10-15 years before clinical application (clinical as in at your doctor's office)

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MemberMember
378
(@rez77)

Posted : 12/03/2016 1:51 am

just so you dingbats realize how slow medicine works look at this newclip from 2007.

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MemberMember
36
(@mjg713)

Posted : 12/03/2016 3:32 pm

14 hours ago, Rez77 said:

3 years away from human trials. The technology is not realizable yet though either which they don't directly
say in this article. I would say clinical application at your local cosmetic surgeon maybe 10-15 years? Maybe....

http://www.cbc.ca/news/technology/printalive-3d-skin-tissue-printer-wins-canadian-dyson-award-1.2770667

lol I guess that's the optimism of youth as you are truly a college kid. 10-15 years before clinical application (clinical as in at your doctor's office)

I have to say you are completely off man. 3d printing of simple tissues of skin, bone, and cartilage will happen in the near future. It will not take 10-15 years because FDA approval does not take that long for this particular procedure. We should see this within 5 years, and this isn't even including the hydrogels being marketed. All that matters is whichever one works and comes fastest. We will probably see much more advanced structures than skin 3d printed in a 10-15 year time frame.

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MemberMember
7
(@scarred2468)

Posted : 12/03/2016 4:30 pm

That printer technology isn't even meant to be scarless, that's not the point of the invention. It's just to close the wound as fast as possible. That's good but not what we're interested in.

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