Okay, thanks.

Hold your horses guys..

remember, in the abstract it is clearly state "regenerative BURN wound heling"

No "acnescar" ...

It doesn't matter. It promotes skin regeneration.

A third degree burn is much more difficult to regenerate than any acne scar.

The skin is complete destroyed and even fat, bone, muscles are affected.

Agree. Acne scars will be treated easier. Most of them are in the dermis.

Just azking for opinion..

is the hydrogel still considered as device? If so, the clinical trial would be fast

Just azking for opinion..

is the hydrogel still considered as device? If so, the clinical trial would be fast

It will be fast if it is successful. If it is not then.....

I know some of you contacted researches. Did you ask them specifically about acne scars? Just wondering what they talk about it.

 

Just azking for opinion..

is the hydrogel still considered as device? If so, the clinical trial would be fast

It will be fast if it is successful. If it is not then.....

What bothers me is that they said Acellular

Anyway, how do you know that it is unsuccessful?

I know some of you contacted researches. Did you ask them specifically about acne scars? Just wondering what they talk about it.

Yeah like i said, how about acne scars? might turn out to be better if we have 3rd degree burn than acne in the end

I'm sure it works on acne scarring. Just wondering if they have plans. You guys have got contacts, so you may ask.

We all read the study where the hydrogel has shown complete regeneration. What does it mean? It means it is POSSIBLE! They continue to work on. They may add growth factors, stem cells, but I believe that they are not necessary. We're close.

Roach, why do you think that dding those things are'nt necessary?

They said that.

The team, led by principal investigator Sharon Gerecht, had originally planned on infusing the hydrogel with stem cells and growth factors. Due to processes they don't fully understand, however, the gel in its basic form was able to grow new skin - complete with hair follicles, blood vessels and skin oil glands. The growth process takes 21 days.

Here it is.

However, I think if they add growth factors and stem cells, it will be completely successful.

no. that was the rat model.

all the models are different. even within humans, old people and young people need different tuning for the hydrogel

no. that was the rat model.

all the models are different. even within humans, old people and young people need different tuning for the hydrogel

How u know that?

it works by helping the body heal. 70 year old man and 1 year old baby heals very differently

There's really no problems. Just take supplements with vitamins, protein, amino acids, and so on and so forth and use good topical stuff before treatment.

Scar free healing my ass acell.

Bringin people hopes to ruin

There's really no problems. Just take supplements with vitamins, protein, amino acids, and so on and so forth and use good topical stuff before treatment.

This is nonsense

Lol what? This is the basic of biology. Those things help the body. How will your body recover without resources?

Are you saying you will be able to recover from skin damage like a baby would if you took supplements??

Currently available skin grafts and skin substitute for healing following third-degree burn injuries is fraught with complications, often resulting in long-term physical and psychological sequelae. Synthetic treatment that can promote wound healing in a regenerative fashion would provide an off-the-shelf, non-immunogenic strategy to improve clinical care of severe burn wounds. Here, we demonstrate vulnerary efficacy and accelerated healing mechanism of dextran-based hydrogel in third-degree porcine burn model. The model was optimized to allow examination of the hydrogel treatment for clinical translation and its regenerative response mechanisms. Hydrogel treatment accelerated third-degree burn wound healing by rapid wound closure, improved reepithelialization, enhanced extracellular matrix remodeling, and greater nerve reinnervation, compared to the dressing treated group. These effects appear to be mediated through the ability of the hydrogel to facilitate a rapid but brief initial inflammatory response that coherently stimulates neovascularization within the granulation tissue during the first week of treatment, followed by an efficient vascular regression to promote a regenerative healing process. Our results suggest that the dextran-based hydrogels may substantially improve healing quality and reduce skin grafting incidents and thus pave the way for clinical studies to improve the care of severe burn injury patients.

Thats what the abstract said

Nope. I mean if I take supplements I will heal better.

Rudy, I don't get it... Please explain it in a nutshell.

I need all of your opinion on the abstract of porcine model guys...

What do you guys think??

The abstract said that hydrogel on pigs got regenerative healinh mechanism by enhancing healing speed

Inflammation is rapid but bried in 1 week only