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Seabs is pointing out the possibility to make a FAQ ,so people can understand what is this better.
We need to change the page a bit.What do you think.
I pointed out via pm that the facebook might need a faq, if the page has faqs.
i think its a good idea, does anyone want to do it?
What are the recuring questions you get?
lol! as you can see by the facebook page i dont get any. You would have to create them out of questions we have all asked and think others might or would like to know
someone asked when the gel will be available.So yeah thats one very first question..
Also we need to identify in FAQ,what is hydrogel,how hydrogel can achieve complete skin regeneration.
what is the next steps of the invention,FDA approved time(less time due to its character as device),what is the
practical range of this invention).Please people add more.
Something like the below do wentworth? Or is it to detailed?
FAQs
When will this be available?
We cant say. This is down to John Hopkins and their lawyers. There is however an article in late December 2011 that states it could be available within a few years as this is a device. There is information on the internet of devices being approved after months. So we guess as soon as this is funded this will be approved within months???
BTW this page was created to hopefully create social awareness and maybe push funding along consequentially. Will this pushing along work? We do not know but we think the getting information on here is proactive, benevolent and can only help; so who knows. We want this information out there so this can be funded sooner. We hope you take notice of the page.
References:
http://www.pnas.org/content/early/2011/12/13/1115973108.full.pdf+html
http://www.sciencedaily.com/releases/2011/12/111213131956.htm
What is this?
This is a degradable scaffold. This is a degradable hydrogel that degrades rapidly when inserted in mammal wounds.
More information:
Degradable scaffolds like the comparison control in the test, equally treated have been tested thousands of time on most mammals, their properties and behaviours are well established.
This particular scaffold is a rapidly degrading dextran hydrogel in a 80:20 ratio. It is cited in the paper as a dextran-allyl isocyanate-ethylamine (Dex-AE)/polyethylene glycol diacrylate (PEGDA) in ratio of 80/20, with a loose interior architecture.
And this ratio of scaffold was chosen over the lower ratio 60:40 dextran hydrogel because of the better cell infiltration, lower crosslinking density properties of the 80/20. Cited in the paper.
This is a degradable scaffold that achieved complete regeneration of tissue, when tested against an established reliable standardised control scaffold. The control scaffold this was tested against is a state of the art scaffold called Integra which has been used thousands of times on all mammal wounds. This control scaffold is currently used in many hospitals in standardised burn treatments. In the test the state of the art control behaved typically and regenerated incompletely. Cited in the paper.
The dextran also degrades rapidly (7 to 10 days), is easily ate by the neutrophils, is very soft and also has a smaller porosity than the control, enabling rapid neutrophil and cell infiltration. Cited in the paper.
Reference:
http://www.pnas.org/content/early/2011/12/13/1115973108.full.pdf+html
What has it achieved? Or what makes it stand out?
The rapidly degrading dextran hydrogel was inserted into a fresh wound from a 3rd degree burn, the wound completely regenerated with appendages, and the wound treated by the control behaved typically. Scar free healing, rapid neovascularization and complete skin regeneration was achieved by dextran hydrogel treated wounds.
Collaborating information:
Neovascularization and angiogenesis determine what the outcome will be in wounds and deep burn injuries. Tredget. New blood vessels participate by providing nutrition and oxygen to growing tissues. Li.
It is known first degree burns heal with no scarring and deep second degree burns heal with scarring and are slow healing, they take more than a month to heal.
It is known that generally if a wound takes over 3 weeks to re-epithelize the end point will result in scarring. Also this knowledge with regards to healing time for scarring has been shown scientifically, Cubison et al.
It is also established that when a scaffold degrades via neutrophils cells are created and when a scaffold does not degrade scarring occurs. Khetan S, Kloxin AM et al
It is known skin appendages do not grow is scar tissue.
Further facts from the paper:
A 3rd degree burn was cut out completely with a full thickness excision; leaving a rim of burned tissue. This standard protocol was following the standard treatment in hospitals with regards to 3rd degree burns using the control scaffold. Following this standard protocol enabled a comparison with the established control.
The wounds were checked at various intervals over 5 weeks to compare the dextran and the controls:
At 5 and 7 days the dextran hydrogel treated wounds vascular networks had expanded and developed even more. The dextran hydrogel had rapid neovascularisation and angiogenesis when compared to the controls.
The dextran hydrogel degraded rapidly in 7 to 10 days and cells were created. The scaffold control did not degrade in that time. The neutrophils where stuck in the peripheral of the control scaffold after day 7.
When the wounds were checked at day 14 the dextran hydrogel had demonstrated epithelial repair. Way before day 21. The scaffold control had not as typical.
When the wounds were checked at day 21, the dextran treated wounds had complete regeneration with appendages. The control behaved typically with incomplete regeneration.
After 5 weeks the wound areas were checked one last time, the hydrogel treated wounds had complete regeneration with appendages and the skin width was found to be normal.
Reference:
http://www.pnas.org/content/early/2011/12/13/1115973108.full.pdf+html
The information for these three above FAQs is creative commons, you are free to share. This information is referenced to the best of human ability. Errors may be in this information, please check the references used.
Seabs is pointing out the possibility to make a FAQ ,so people can understand what is this better.
We need to change the page a bit.What do you think.I pointed out via pm that the facebook might need a faq, if the page has faqs.
i think its a good idea, does anyone want to do it?
What are the recuring questions you get?
lol! as you can see by the facebook page i dont get any. You would have to create them out of questions we have all asked and think others might or would like to know
Its not distracting to ask why something promotes healing.
Yes yes i know results matter that can be repeated over and over
and show factual evidence but still its not distracting at all to ask why
somehting could show the way to scarless healing...
But you are right maybe we will never find this knowledge
but thinking like this can expand the limits and even make new theories an treatments.
I believe the technology and scarless healing exists.. as does life extension technology but the leaders, power hungry control freaks that run the world will not allow the people to have these things (only for themselves) because they will want to continue making money through other pharmaceuticals and such but that doesn't mean that we should give up. If anything , our efforts should be that much more to bring this into the mainstream..and having read some of these posts..facebook is a start ( most people on facebook will want to remain anonymous to their friends about this) but collectively we can locate the solution. This is a time to make it happen..we have the internet today which brings us in touch with virtually anyone with the click of a button..all it takes is the right party..when enough people demand something it can break down the barrier...
Well said.
Okay, if there's someone on this thread who is a skin scientist or dermatologist or know a skin scientists or dermatologist would they be able to evaluate the viability of this? I'm not trying to annoy anyone, I want this to be real as much as anyone. I'm simply perplexed why if it's real it hasn't made a bigger splash yet or been developed?
Okay, if there's someone on this thread who is a skin scientist or dermatologist or know a skin scientists or dermatologist would they be able to evaluate the viability of this? I'm not trying to annoy anyone, I want this to be real as much as anyone. I'm simply perplexed why if it's real it hasn't made a bigger splash yet or been developed?
If you really are interested in having a dermatologist evaluate the viability of the hydrogel all you need to do is pick up the phone, call one and ask. I've phoned a few dermatologists in the past. They didn't mind. Of course they are busy people but I think enough of them are willing to take the time to answer a short question.
Okay, if there's someone on this thread who is a skin scientist or dermatologist or know a skin scientists or dermatologist would they be able to evaluate the viability of this? I'm not trying to annoy anyone, I want this to be real as much as anyone. I'm simply perplexed why if it's real it hasn't made a bigger splash yet or been developed?
If you really are interested in having a dermatologist evaluate the viability of the hydrogel all you need to do is pick up the phone, call one and ask. I've phoned a few dermatologists in the past. They didn't mind. Of course they are busy people but I think enough of them are willing to take the time to answer a short question.
I was thinking about this while doing the dishes. haha Here's a phone number:
0251 275 555
Ask for Esther Middelkoop. She'll be able to tell you if it is viable or not. But quite honestly I think she'll just say "We'll just have to wait and see. There might a possibility that it will work but I don't know how likely that is. Scarfree healing will come around but it's probably going to take another 20 to 30 years.".
Okay, if there's someone on this thread who is a skin scientist or dermatologist or know a skin scientists or dermatologist would they be able to evaluate the viability of this? I'm not trying to annoy anyone, I want this to be real as much as anyone. I'm simply perplexed why if it's real it hasn't made a bigger splash yet or been developed?
The science is cold and objective, and note, simple and testable, and not opinion. All any derm could do is objectively note the 'results' with what ever paper they look at.
I believe the technology and scarless healing exists.. as does life extension technology but the leaders, power hungry control freaks that run the world will not allow the people to have these things (only for themselves) because they will want to continue making money through other pharmaceuticals and such but that doesn't mean that we should give up. If anything , our efforts should be that much more to bring this into the mainstream..and having read some of these posts..facebook is a start ( most people on facebook will want to remain anonymous to their friends about this) but collectively we can locate the solution. This is a time to make it happen..we have the internet today which brings us in touch with virtually anyone with the click of a button..all it takes is the right party..when enough people demand something it can break down the barrier...
This is what every scam artist, snakeoil salesman, quack says (conspiracy theories that their 'cures' are forbidden by evil multinational companies, lobbies and governments), the truth is that the essential problem is that we are a type 0 civilization on Kardashev scale, it is the most primitive civilization with the most primitive technology on that scale, I mean it is the fact that 85% of global energy demand is still met by fossil fuels (which are in fact dead plants), we still have no cures for cancer (for example 5 year survival rate for pancreatic cancer is still just 5%, one of the victims of that disease was Steve Jobs, so billionaires are not spared, of course), heart diseases, autoimmune diseases (multiple sclerosis, ALS,...), neurodegenerative diseases (Alzheimer's, Huntington's), in fact ICT is the only one that is rapidly advancing and all other technologies were pretty stagnant (that is because Moore's law was until recently relevant only for ICT), so as a result instead of stuffs like free energy and cures for cancer and other diseases we have smartphones, tablets, social networks, GPS navigation in our cars, broadband connections, consumerism and advertising, digital and cable TV so we can watch MTV, Fashion TV and listen trash music like Lady Gaga, I mean it is mostly useless garbage, it is the cruel reality, however the good news is that we are now in the early transition from a type 0 to a type 1 civilization on Kardashev scale and as a result we now have many new promising experimental technologies, for example we have self driving cars (Google driverless car), electric cars (Tesla Model S), Moore's law is relevant for solar power (the price of solar panels drops by a half every 2 years) and for genetics and medicine, we have nuclear fusion research (ITER, DEMO) and regenerative medicine and stem cells research are one of the fastest growing fields of science, so I advise you to read the book 'Physics of the Future' from Michio Kaku, there you can find pretty optimistic but still realistic vision of the future of many medical and non-medical technologies, one part of the book is dedicated to regenerative medicine and stem cells, scarless skin healing is not mentioned in the book but there are mentions of new experimental cures for spinal cord injury and for heart damage after a heart attack which are essentially the same problem as skin scars.
http://www.amazon.com/Physics-Future-Science-Shape-Destiny/dp/0307473333
I believe the technology and scarless healing exists.. as does life extension technology but the leaders, power hungry control freaks that run the world will not allow the people to have these things (only for themselves) because they will want to continue making money through other pharmaceuticals and such but that doesn't mean that we should give up. If anything , our efforts should be that much more to bring this into the mainstream..and having read some of these posts..facebook is a start ( most people on facebook will want to remain anonymous to their friends about this) but collectively we can locate the solution. This is a time to make it happen..we have the internet today which brings us in touch with virtually anyone with the click of a button..all it takes is the right party..when enough people demand something it can break down the barrier...
This is what every scam artist, snakeoil salesman, quack says (conspiracy theories that their 'cures' are forbidden by evil multinational companies, lobbies and governments), the truth is that the essential problem is that we are a type 0 civilization on Kardashev scale, it is the most primitive civilization with the most primitive technology on that scale, I mean it is the fact that 85% of global energy demand is still met by fossil fuels (which are in fact dead plants), we still have no cures for cancer (for example 5 year survival rate for pancreatic cancer is still just 5%, one of the victims of that disease was Steve Jobs, so billionaires are not spared, of course), heart diseases, autoimmune diseases (multiple sclerosis, ALS,...), neurodegenerative diseases (Alzheimer's, Huntington's), in fact ICT is the only one that is rapidly advancing and all other technologies were pretty stagnant (that is because Moore's law was until recently relevant only for ICT), so as a result instead of stuffs like free energy and cures for cancer and other diseases we have smartphones, tablets, social networks, GPS navigation in our cars, broadband connections, consumerism and advertising, digital and cable TV so we can watch MTV, Fashion TV and listen trash music like Lady Gaga, I mean it is mostly useless garbage, it is the cruel reality, however the good news is that we are now in the early transition from a type 0 to a type 1 civilization on Kardashev scale and as a result we now have many new promising experimental technologies, for example we have self driving cars (Google driverless car), electric cars (Tesla Model S), Moore's law is relevant for solar power (the price of solar panels drops by a half every 2 years) and for genetics and medicine, we have nuclear fusion research (ITER, DEMO) and regenerative medicine and stem cells research are one of the fastest growing fields of science, so I advise you to read the book 'Physics of the Future' from Michio Kaku, there you can find pretty optimistic but still realistic vision of the future of many medical and non-medical technologies, one part of the book is dedicated to regenerative medicine and stem cells, scarless skin healing is not mentioned in the book but there are mentions of new experimental cures for spinal cord injury and for heart damage after a heart attack which are essentially the same problem as skin scars.
http://www.amazon.com/Physics-Future-Science-Shape-Destiny/dp/0307473333
Vladislav, you're a smart guy and I thank you because you give me hope. I'm also terrified of aging. I know it's narcissistic but it frightens me to no end.
I do really believe regeneration of body tissues,is not as complex as commercial medicine wants you to think or at least makes you think.
Seriousy, why do you say that, panos?
I see it in my iodine tincture experiment.I see how regeneration begins from bottom to up.
Who thought an iodine tincture 2% that cost 2.5 euros would beat the hell out of every equipment dermatologists have.
It a slow process but still much better than most of the things others want you to buy.
But who will care about an iodine liquid that cost 3 euros and make a solid routine out of it with some enchanced knowledge.
Naahhh,there is no profit in it.
All we can do is to experiment.Hard core commerial societies is what block us from regenerating.
Dr Derry reported complete scar regeneration of 50year old scar from mole removal in 2009 by topical iodine.
Medical community didnt give a fuck about it all these years.
We need to take all the stuff that have worked for people and make a solid routine.
I do really believe regeneration of body tissues,is not as complex as commercial medicine wants you to think or at least makes you think.
Seriousy, why do you say that, panos?
I see it in my iodine tincture experiment.I see how regeneration begins from bottom to up.
Who thought an iodine tincture 2% that cost 2.5 euros would beat the hell out of every equipment dermatologists have.
It a slow process but still much better than most of the things others want you to buy.
But who will care about an iodine liquid that cost 3 euros and make a solid routine out of it with some enchanced knowledge.
Naahhh,there is no profit in it.
All we can do is to experiment.Hard core commerial societies is what block us from regenerating.
Dr Derry reported complete scar regeneration of 50year old scar from mole removal in 2009 by topical iodine.
Medical community didnt give a fuck about it all these years.
We need to take all the stuff that have worked for people and make a solid routine.
Thanks man. I'll reply to your reply properly when I have the time.
I do really believe regeneration of body tissues,is not as complex as commercial medicine wants you to think or at least makes you think.
Seriousy, why do you say that, panos?
I see it in my iodine tincture experiment.I see how regeneration begins from bottom to up.
Who thought an iodine tincture 2% that cost 2.5 euros would beat the hell out of every equipment dermatologists have.
It a slow process but still much better than most of the things others want you to buy.
But who will care about an iodine liquid that cost 3 euros and make a solid routine out of it with some enchanced knowledge.
Naahhh,there is no profit in it.
All we can do is to experiment.Hard core commerial societies is what block us from regenerating.
Dr Derry reported complete scar regeneration of 50year old scar from mole removal in 2009 by topical iodine.
Medical community didnt give a fuck about it all these years.
We need to take all the stuff that have worked for people and make a solid routine.
I agree that to a degree there is this thing going on where people try to sell us things that only do so much and it's a commercial thing. There's plenty of people who try to make money that way. A dermatologist I spoke to once told confirmed this.
But there really are plenty of people who mean well and who try to have things go forward as fast and as far as they can.
Not the most interesting reply I gave but I said I would reply, so... 
Don't really know what else to say.
http://blip.tv/baldtruthgfq/spencer-kobren-s-the-bald-truth-ep-67-3-26-13-6560692
Someone seems to be coming out with a so-called scarless hair transplant thing. It may be interesting.
Just forget this
The creator is a selfish, investors will want to be part of the profits and the creator of this gel does not want to share anything, which is why they will never find a 'foundation'. creator wants to be free money gain the sole. is imposible.no dream.forget this.
No dream.
Just forget this
The creator is a selfish, investors will want to be part of the profits and the creator of this gel does not want to share anything, which is why they will never find a 'foundation'. creator wants to be free money gain the sole. is imposible.no dream.forget this.
No dream.
Ok.
Just forget this
The creator is a selfish, investors will want to be part of the profits and the creator of this gel does not want to share anything, which is why they will never find a 'foundation'. creator wants to be free money gain the sole. is imposible.no dream.forget this.
No dream.
it should come out in 5 years!
Well there is some true in what Maldition says.
There is a factual basis about Hydrogel. It is valuable.It will help many people.
So it comes down to the team. They should choose a pathway,and this one is very similar to the most fundmanetal way of living that all we should be asking ourselves about. :
Two options:
a) Waiting for fund .FDA approval.Commercial Marketing.
b) Getting out of this crap . A true independent scientist would never care to follow some higher obligatory rules.
A true scientist knows ,that there is only a problem and a solution to the problem.Everything else is just drawing circles around the problem.
A true scientist will join these forums.
What I don't understand is why any of you think this thing is in need of funding!!!??? Seriously, I'm not trying to piss anyone off, I'm just curious, why do you think
it needs funding. I mean if anything if this were possible every major corporation, drug company, pfizer, etc. you name it in the world would basically be trying to woo these guys or the university or whatever. The desirability of this product would be like if Michael Jordan were suddenly a free agent during the height of the Chicago Bulls' success EXCEPT TIMES A BILLION!!!!
I mean this wouldn't just have implications for acne scars or burn scars it would revolutionize humanity. So sorry, I don't believe it. I don't even care if there's a
scientific paper --it could have just been some kind of freak occurrence that happened with the lizards or something and/or they've tried to reproduce it a bunch of times and it hasn't worked. I'm starting to realize it is highly improbably that any of this shit actually works. I think it's important that there are dissenting voices on this thread. Cause SOMEBODY GOTTA KEEP IT REAL.