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Well ok, wounds treated with hydrogel have 6 to 10 times more hair follicles than the control wounds, and besides more hair follicules there are sebaceous glands, more blood vessels, vessels are larger in diameter and there is a normal skin thickness.
And as I said 8mm full thickness wounds are very large wounds for very small animals like mice, and the death rate of control mice was 40%. And 8mm FTE wounds are not very large wounds for pigs and humans.
And here is what dr Sun said to chuckstonchew:
I talked to Dr. Sun again today too. He said Gerecht hopes he can continue to work with the hydrogel if it gets funding by next year as he's been working with dextran for the past 10 years so he knows it better than anyone. But he does start his new position away from Johns Hopkins next month.
He also said that with the 501k process, he thinks the hydrogel could get FDA approval in as little as 3 months. He said they just need one more preclinical test (with pigs - which in his 10 year experience he says regenerate better than mice). He also said that he is confident that it will work on humans if there is funding...
Umm.. Yeah lol, I was talking about scientific papers in general.. not any particular one. If any of you believe that this hydrogel is real.. I can assume that you are jumping around in joy that your troubles are soon coming to an end. But I'm pretty sure none of you are doing that because you know that it is probably more likely that it doesn't work. But I am hopeful..
It regenerated a third degree burn completely, the control did not. fact. No reasoning from an opinion is needed. It was degraded rapidly by the bodies neutrophils, the 'body regenerated completely. This is the find of this current century to us. This is how good this is, and it needs funded asap. They have proven a linear link between cell creation and scaffold digestion <<<<. They have proven scar free heaing of a third degree burn via the rapid digestion of a hydrogel. They have also proven scarring via the slow digestion of a scaffold.<<<<< This to me is transparent. It is transparent to me that the only thing that can stop this is if you put something in your body that is slowly dgested, or you have a poor immune system, those are the only two permutations needed to disrupt it. Now to me all mammals have immune systems neutrophils that would digest this simple hydrogel sugar, And guess what would happen when they digest this rapidly? Can you elucidate it?
anyway - one thing I will say about the gel is this - it managed after third degree burns to grow new skin with hair and appendages on all the mice with hydrogel - and this has NEVER happened in the test mouse's skin before in all of history - heck, 40% of the mice is a control group didn't even survive - what they did was a breakthrough - and if it does the same thing on a larger animals skin - like a pig - and by 'completely regenerated' this means that their skin texture and color returns to normal then we really will have a great hope - I know until the larger animals experiments are done - which I believe they will be - that no one should pin their hopes on this - but as it stands I give this gel a 50/50 chance of helping my scars in the future which is better than the 0% chance I had with anything in development before
This is one of my problems with your and seab's reasoning. Regrowth of appendages happens all the time. It happened in the control mice (see pic below) just as it happened in the fifties when this form of regeneration in adult skin first was discovered. There is no sharp line between perfect regeneration and no regeneration at all.
I've never said appendage regrowth doesn't happen all the time, I've said, appendages do not regenerate in scar tissue, which is a fact.
BTW in that data from the paper the case for the hydrogel is highlighted even more. Also the reason a little appendage growth happened in the control and dressing here is because there was a little regeneration ('note 'incomplete regeneration'); every tissue has a tiny bit of regeneration in healing. It is just the process is usually gazumped by scar tissue which denies the complete regeneration state. Appendages prove healing without scar in were they grow. Still appendages do not grow in scar. In no way have I said there is either scarring or regeneration in a dichotomy here. I've discussed 'complete regeneration' or 'incomplete regeneration.' Incomplete regeneration actually has regeneration and scarring.
Umm.. Yeah lol, I was talking about scientific papers in general.. not any particular one. If any of you believe that this hydrogel is real.. I can assume that you are jumping around in joy that your troubles are soon coming to an end. But I'm pretty sure none of you are doing that because you know that it is probably more likely that it doesn't work. But I am hopeful..
It regenerated a third degree burn completely, the control did not. fact. No reasoning from an opinion is needed. It was degraded rapidly by the bodies neutrophils, the 'body regenerated completely. This is the find of this current century to us. This is how good this is, and it needs funded asap. They have proven a linear link between cell creation and scaffold digestion <<<<. They have proven scar free heaing of a third degree burn via the rapid digestion of a hydrogel. They have also proven scarring via the slow digestion of a scaffold.<<<<< This to me is transparent. It is transparent to me that the only thing that can stop this is if you put something in your body that is slowly dgested, or you have a poor immune system, those are the only two permutations needed to disrupt it. Now to me all mammals have immune systems neutrophils that would digest this simple hydrogel sugar, And guess what would happen when they digest this rapidly? Can you elucidate it?
I don't understand why a complete digestion of a scaffold is so important, there is no complete skin regeneration without complete digestion of a scaffold or what?
I've never said appendage regrowth doesn't happen all the time, I've said, appendages do not regenerate in scar tissue, which is a fact.BTW in that data from the paper the case for the hydrogel is highlighted even more. Also the reason a little hair growth happened in the control and dressing here is because there was a little regeneration ('note 'incomplete regeneration'); every tissue has a tiny bit of regeneration in healing. It is just the process is usually gazumped by scar tissue which denies the complete regeneration state. Appendages prove healing without scar in were they grow. Still appendages do not grow in scar. In no way have I said there is either scarring or regeneration in a dichotomy here. I've discussed 'complete regeneration' or 'incomplete regeneration.' Incomplete regeneration actually has regeneration and scarring.
So first you're saying that appendages don't regenerate in scar tissue, and then you say that there was "a little regeneration" in the control. Either you haven't made up your mind, or you're actually saying that there were spotted areas where there was not enough scar tissue to prevent appendages from regrowing in the control, which is absurd. Appendage regeneration and fibrosis are not two mutually exclusive phenomena.
Anyway, your logic is faulty. This is what we all can agree on:
- There is a range of healing outcomes: from dense scar tissue to perfect regeneration
- Some appendages nearly always regrow in deep wounds, given that the wound is large enough
- The hydrogel increased the number of hair follicles that regrew
How the f.. can you come to the conclusion that the hydrogel perfectly regenerated the skin without even comparing adnexal density to what normal skin should have? Also, note the extremely high standard deviation in hair follicle density in the chart: by the empirical rule, about 16% of the mice in the hydrogel group grew less than ~7 hair follicles / mm (!)
How the f.. can you come to the conclusion that the hydrogel perfectly regenerated the skin...
Again, how about the scientific, peer reviewed publication by doctors at the highly respected Johns Hopkins University that clearly stated 'Complete Skin Regeneration' several times?
This doesn't really seem equivocal to me, I'm not certain why we're arguing over this? Do you think that these doctors are lying or what..?
I mean I know this doesn't necessarily warrant direct translation into humans and thus there could be argument/discussion as to whether or not it'll truly be our skin panacea but I mean, from what we know as of now, it seems pretty promising. Definitely promising enough for us to be excited and hopeful.
I don't understand why a complete digestion of a scaffold is so important, there is no complete skin regeneration without complete digestion of a scaffold or what?
What has been proven in the paper is when the hydrogel digests cells are created. The faster this happens, the less scar, the slower the digestion happens the more scar.
So first you're saying that appendages don't regenerate in scar tissue, and then you say that there was "a little regeneration" in the control. You said.
I have stated as a matter of fact, appendages do not grow in scar tissue. Which is a fact. I have not stated that healing is a dichotomy ever? So I regard you pointing logic here as flawed. Healing can have two outcomes, complete regeneration, or incomplete regeneration. Complete regeneration is the process where you new tissue is exactly like before. Incomplete regeneration is incomplete regeneration, there is a mixture of scar tissue and regeneration. And scar tissue blocks of regeneration. BTW I have cited this standard earlier.
Either you haven't made up your mind, or you're actually saying that there were spotted areas where there was not enough scar tissue to prevent appendages from regrowing in the control, which is absurd. Appendage regeneration and fibrosis are not two mutually exclusive phenomena. You said.
Is it really absurd using the evidence in the paper were the hydrogel got complete regeneration and the control did not, to state that as the hydrogel which had no scarring blocking off tissues it regenerated more appendages and the control? Is that really absurd. I take offense, in you insinuating I havent made up my mind, or using trigger words like absurd here lol. I have never moved the goal posts, I cant rewrite pdfs and websites. And this is not a fing debate (btw that was mock anger). What I have said is backed up and validated in the main, again, this is not my fing opinion. (mock anger again) Appendages cannot regenerate in scar tissue which is a fact.
How the f.. can you come to the conclusion that the hydrogel perfectly regenerated the skin without even comparing adnexal density to what normal skin should have? Also, note the extremely high standard deviation in hair follicle density in the chart: by the empirical rule, about 16% of the mice in the hydrogel group grew less than ~7 hair follicles / mm (!) you said.
Mr Guru, I fing (mock anger) come to the conclusion as that is what it states in the paper, along with the fact they compared the completely regenerated tissue alongside the incompletely regenerated tissue, along with the standard definition of complete regeneration cited again, along with the fact this is the definition the papers authors used http://www.sciencedaily.com/releases/2011/12/111213131956.htm , along with the fact all the skins appendages were regenerated, all cited. You can use incomplete regeneration if you want, but remember it is not cited and we can then say correctly your logic is flawed.
Umm.. Yeah lol, I was talking about scientific papers in general.. not any particular one. If any of you believe that this hydrogel is real.. I can assume that you are jumping around in joy that your troubles are soon coming to an end. But I'm pretty sure none of you are doing that because you know that it is probably more likely that it doesn't work. But I am hopeful..
Hydrogel: New Hope for novice users.
@scars4life - I just noticed that you joined here in 2009 and choose the username 'Scars4life' - I think it's cool that you are skeptical - and it's everyone's right to say anything they want - but am just wondering why you choose that username - was it something to do with renovo or other projects that didn't work out?
anyway - one thing I will say about the gel is this - it managed after third degree burns to grow new skin with hair and appendages on all the mice with hydrogel - and this has NEVER happened in the test mouse's skin before in all of history - heck, 40% of the mice is a control group didn't even survive - what they did was a breakthrough - and if it does the same thing on a larger animals skin - like a pig - and by 'completely regenerated' this means that their skin texture and color returns to normal then we really will have a great hope - I know until the larger animals experiments are done - which I believe they will be - that no one should pin their hopes on this - but as it stands I give this gel a 50/50 chance of helping my scars in the future which is better than the 0% chance I had with anything in development before
Well there really isn't much to my username selection, I don't think I even knew much about renovo at the time, I just thought it was a fitting name. The hot topic when I came around was fixing scars with stem cells. I was pretty much against that, especially with the price tag it carried. But basically every treatment that was gaining popularity I was almost always against and I used to call people out on it, so I guess I was sort of a controversial figure around here. But we are here now and none of them worked, so maybe I wasn't that crazy. As far as hydrogel goes I haven't really made up much opinion on it as I have not done much research on the subject due to the fact that I stopped being a regular here. But this week I finish my MS in Computer Science degree, and I'll come around here more often to see what's up.
If the hydrogel can achieve what is being claimed then we might just have something here. My only problem with it, is not even its validity, but its methods. It just seems way too simple, if the method was to turn of some genes or injections or something, then it would be much more believable. But you know if it sounds too good to be true it probably is. But like I said I don't know much about the matter so I don't want to bring someone's day down.
Just everyone don't pin so much hope on this thing, stay calm ok?
A pessimist is really an optimist with experience. 
@scars4life - I just noticed that you joined here in 2009 and choose the username 'Scars4life' - I think it's cool that you are skeptical - and it's everyone's right to say anything they want - but am just wondering why you choose that username - was it something to do with renovo or other projects that didn't work out?
anyway - one thing I will say about the gel is this - it managed after third degree burns to grow new skin with hair and appendages on all the mice with hydrogel - and this has NEVER happened in the test mouse's skin before in all of history - heck, 40% of the mice is a control group didn't even survive - what they did was a breakthrough - and if it does the same thing on a larger animals skin - like a pig - and by 'completely regenerated' this means that their skin texture and color returns to normal then we really will have a great hope - I know until the larger animals experiments are done - which I believe they will be - that no one should pin their hopes on this - but as it stands I give this gel a 50/50 chance of helping my scars in the future which is better than the 0% chance I had with anything in development before
Well there really isn't much to my username selection, I don't think I even knew much about renovo at the time, I just thought it was a fitting name. The hot topic when I came around was fixing scars with stem cells. I was pretty much against that, especially with the price tag it carried. But basically every treatment that was gaining popularity I was almost always against and I used to call people out on it, so I guess I was sort of a controversial figure around here. But we are here now and none of them worked, so maybe I wasn't that crazy. As far as hydrogel goes I haven't really made up much opinion on it as I have not done much research on the subject due to the fact that I stopped being a regular here. But this week I finish my MS in Computer Science degree, and I'll come around here more often to see what's up.
If the hydrogel can achieve what is being claimed then we might just have something here. My only problem with it, is not even its validity, but its methods. It just seems way too simple, if the method was to turn of some genes or injections or something, then it would be much more believable. But you know if it sounds too good to be true it probably is. But like I said I don't know much about the matter so I don't want to bring someone's day down.
Just everyone don't pin so much hope on this thing, stay calm ok?
A pessimist is really an optimist with experience.
@scars4life congrats on your MS!
I know what you're saying - and when it comes to medical experimentation you have to be especially cautious about getting hopes up!
I am following this with keen interest though - it seems different than all the other things I've read about for regenerating skin - but I also know that the next stage experiments will show whether it really has great potential or not.
For a few years now I've been reading about skin regeneration and all the different methods tried since the 70s - and even before - and why this excited me is from what I read it seemed some sort of new scaffold would be the answer to preventing scarring - and then I read about this scaffold developed from by scientists creating completely new structures within the gel
It's tantalizing - and I'll just have to wait...
re. the science daily interview with the JH team that someone else quoted [ http://www.sciencedaily.com/releases/2011/12/111213131956.htm ]
I found the following interesting...
Sun added, "Complete skin regeneration is desired for various wound injuries. With further fine-tuning of these kinds of biomaterial frameworks, we may restore normal skin structures for other injuries such as skin ulcers."
Gerecht and Harmon say they don't fully understand how the hydrogel dressing is working. After it is applied, the tissue progresses through the various stages of wound repair, Gerecht said. After 21 days, the gel has been harmlessly absorbed, and the tissue continues to return to the appearance of normal skin.
The word 'normal' is used twice - and even normal appearance... but does normal mean - the skin is just functioning and might stil look slightly odd - or would it look just like it did before it scarred? back to the million dollar question lol...
i think
It's kind of interesting too that the scientists say that THEY don't quite know how it's working - somehow that makes me more hopeful about it as I think a lot of breakthroughs are actually quite accidental and scientists have to work backwards to find out how a drug or therapy worked!
@scars4life - I just noticed that you joined here in 2009 and choose the username 'Scars4life' - I think it's cool that you are skeptical - and it's everyone's right to say anything they want - but am just wondering why you choose that username - was it something to do with renovo or other projects that didn't work out?
anyway - one thing I will say about the gel is this - it managed after third degree burns to grow new skin with hair and appendages on all the mice with hydrogel - and this has NEVER happened in the test mouse's skin before in all of history - heck, 40% of the mice is a control group didn't even survive - what they did was a breakthrough - and if it does the same thing on a larger animals skin - like a pig - and by 'completely regenerated' this means that their skin texture and color returns to normal then we really will have a great hope - I know until the larger animals experiments are done - which I believe they will be - that no one should pin their hopes on this - but as it stands I give this gel a 50/50 chance of helping my scars in the future which is better than the 0% chance I had with anything in development before
Well there really isn't much to my username selection, I don't think I even knew much about renovo at the time, I just thought it was a fitting name. The hot topic when I came around was fixing scars with stem cells. I was pretty much against that, especially with the price tag it carried. But basically every treatment that was gaining popularity I was almost always against and I used to call people out on it, so I guess I was sort of a controversial figure around here. But we are here now and none of them worked, so maybe I wasn't that crazy. As far as hydrogel goes I haven't really made up much opinion on it as I have not done much research on the subject due to the fact that I stopped being a regular here. But this week I finish my MS in Computer Science degree, and I'll come around here more often to see what's up.
If the hydrogel can achieve what is being claimed then we might just have something here. My only problem with it, is not even its validity, but its methods. It just seems way too simple, if the method was to turn of some genes or injections or something, then it would be much more believable. But you know if it sounds too good to be true it probably is. But like I said I don't know much about the matter so I don't want to bring someone's day down.
Just everyone don't pin so much hope on this thing, stay calm ok?
A pessimist is really an optimist with experience.
@scars4life congrats on your MS!
I know what you're saying - and when it comes to medical experimentation you have to be especially cautious about getting hopes up!
I am following this with keen interest though - it seems different than all the other things I've read about for regenerating skin - but I also know that the next stage experiments will show whether it really has great potential or not.
For a few years now I've been reading about skin regeneration and all the different methods tried since the 70s - and even before - and why this excited me is from what I read it seemed some sort of new scaffold would be the answer to preventing scarring - and then I read about this scaffold developed from by scientists creating completely new structures within the gel
It's tantalizing - and I'll just have to wait...
re. the science daily interview with the JH team that someone else quoted [ http://www.scienceda...1213131956.htm ]
I found the following interesting...
Sun added, "Complete skin regeneration is desired for various wound injuries. With further fine-tuning of these kinds of biomaterial frameworks, we may restore normal skin structures for other injuries such as skin ulcers."
Gerecht and Harmon say they don't fully understand how the hydrogel dressing is working. After it is applied, the tissue progresses through the various stages of wound repair, Gerecht said. After 21 days, the gel has been harmlessly absorbed, and the tissue continues to return to the appearance of normal skin.
The word 'normal' is used twice - and even normal appearance... but does normal mean - the skin is just functioning and might stil look slightly odd - or would it look just like it did before it scarred? back to the million dollar question lol...
i think
It's kind of interesting too that the scientists say that THEY don't quite know how it's working - somehow that makes me more hopeful about it as I think a lot of breakthroughs are actually quite accidental and scientists have to work backwards to find out how a drug or therapy worked!
A non healing skin ulcer is were the immune system is compromised, usually from end stage diabetes. The whiteblood cell response is no doubt weaker (btw I haven't cited this as fact). Anyway the whiteblood cells is what digests the gel rapidly, which has been stated... I would say an ulcer is different to a normal wound for the reason it wont heal and the immune response is slower. Also after 21 days the regeneration is still immature, e.g the appendage growth isnt at full length yet...
Hi,
New member but have been following this forum for a while. Took a lot of hope from reading the initial publication about the hydrogel. Really would like to know what the latest is. Has there still been no word on funding? It's been around a year since the paper was released but wouldn't the results have known long beforehand? Knowing the hydrogel's potential, not just to help transform lives, but to make millions of dollars it's impossible that some serious progress (prositive or negative) wouldn't have been made in the intervening period. Remember the money Renovo where able to generate. I know what's been reported here by chuckstonchew following contact with Prof Harmon and I'm really grateful for that, as I'm sure a lot of others are. Was there any news on modified hydrogel with the antibiotic layer? I guess we have to be patient, they aren't going to get into details, but that's easier said that done.
Also, I would find it very difficult to believe/understand if Guoming Sun was allowed to leave the project, it looks like he's been the one working on hydrogels from the early days. Losing him would be a big negative. I know there was an issue with funding he's position but a university like JH surely would be able to find the funds. He's still listed as being a member of the Gerecht lab:
http://www.jhu.edu/chembe/gerecht/members.htm
chuckstonchew, have you been in contact with him at all?
I haven't just come on here to release fustration, I do have a suggestion of something we can do to feel a little less helpless. I think we should make chuckstonchew our official contact with JH 
. He's done such a good job already. Maybe if we all were to sign up/create a group large enough then JH may keep us better informed. A genuine group of those affected by scarring.
Just putting it out there to see what you guys think.
Hello genuine. Welcome to the forum. I appreciate your kind words. 
Still no word from Dr. Harmon since the last time I spoke to him in early November. He's a busy man so I don't like to bombard him with emails (I want to stay on his good side) but rest assured, I will speak with him eventually. He seems to be a kind and genuine person and he doesn't mind giving us insight into the project - as was Dr. Sun before his departure. Furthermore, I don't think they can do any type of trials with the new self-adhering, antibiotic version until they've received funding, which again, as of a month ago they have not. So no word on that either I'm afraid.
I will say, when I've spoken to Dr. Harmon and Dr. Sun, they've both referred to their hope to get funding 'next year'. I don't know if the grant they've applied for is something that is rewarded in (hopefully the beginning of) 2013 or what but they've both mentioned this (and I haven't spoken with Dr. Sun since like July or something). Pertaining to Sun being the most experienced and leaving JHU - When I last spoke to him, he also said that Gerecht hopes to bring him back on the team if and when funding is gathered. His Johns Hopkins email has since been deactivated, solidifying his departure. 
I agree though, he needs to be on the team.
I like your idea though. I already consider us to be this type of group and in fact, that's what I refer to us as whenever I contact any of the researchers or other professional places in my hunt for answers and progression. It would be a good move to officialize it though. Maybe we should make an official website/forum or something - with an organization name that we can refer to ourselves as. At this point, I think the people at JHU that I've spoken with do consider us to be a pretty official scar support group, because that's how I've presented us. But in the future (if we work with them on garnering funds for example) it would help for us to be more official and not just some people who talk on the acne.org forums. Ideas/thoughts everyone?
Oh - and on another note, I came across this today -
http://ijl.sagepub.com/content/11/4/264.abstract
Published in late October this year. Seems they have regenerated skin and appendages in a full thickness wound as well.
Good find chuckstonchew! Maybe the hydrogel isn't the only hope for a solution in the near future. And that was in China so it will probably move quicker.
@Maldition, on decorin I actually contacted Dr. Erkki Ruoslahti last year who was/is working CAR-decorin for the treatment of wounds. I posted his exact response some time ago on this board and he stated that no appendages regenerated in the treated tissue. 
But it appears with the hydrogel and news of the novel treatment in China that chuckstonchew posted about we might not need that anyway.
Hello genuine. Welcome to the forum. I appreciate your kind words.
Still no word from Dr. Harmon since the last time I spoke to him in early November. He's a busy man so I don't like to bombard him with emails (I want to stay on his good side) but rest assured, I will speak with him eventually. He seems to be a kind and genuine person and he doesn't mind giving us insight into the project - as was Dr. Sun before his departure. Furthermore, I don't think they can do any type of trials with the new self-adhering, antibiotic version until they've received funding, which again, as of a month ago they have not. So no word on that either I'm afraid.
I will say, when I've spoken to Dr. Harmon and Dr. Sun, they've both referred to their hope to get funding 'next year'. I don't know if the grant they've applied for is something that is rewarded in (hopefully the beginning of) 2013 or what but they've both mentioned this (and I haven't spoken with Dr. Sun since like July or something). Pertaining to Sun being the most experienced and leaving JHU - When I last spoke to him, he also said that Gerecht hopes to bring him back on the team if and when funding is gathered. His Johns Hopkins email has since been deactivated, solidifying his departure.
I like your idea though. I already consider us to be this type of group and in fact, that's what I refer to us as whenever I contact any of the researchers or other professional places in my hunt for answers and progression. It would be a good move to officialize it though. Maybe we should make an official website/forum or something - with an organization name that we can refer to ourselves as. At this point, I think the people at JHU that I've spoken with do consider us to be a pretty official scar support group, because that's how I've presented us. But in the future (if we work with them on garnering funds for example) it would help for us to be more official and not just some people who talk on the acne.org forums. Ideas/thoughts everyone?
Oh - and on another note, I came across this today -
http://ijl.sagepub.c.../4/264.abstract
Published in late October this year. Seems they have regenerated skin and appendages in a full thickness wound as well.
Good find.
Good find chuckstonchew! Maybe the hydrogel isn't the only hope for a solution in the near future. And that was in China so it will probably move quicker.
@Maldition, on decorin I actually contacted Dr. Erkki Ruoslahti last year who was/is working CAR-decorin for the treatment of wounds. I posted his exact response some time ago on this board and he stated that no appendages regenerated in the treated tissue.
But it appears with the hydrogel and news of the novel treatment in China that chuckstonchew posted about we might not need that anyway.
Your non wounded tissues are flooded with decorn 247. The problem with this stuff, imo, is an injection would be used in hours.
Somehow everyone ignored my post, so I'll repost this 
http://www.ncbi.nlm.nih.gov/pubmed/22419870
Although this only brought complete regeneration in second-degree scalding injuries, I think it's still interesting.
This method of using EPO is based on a german patent that's been postet in this topic.
Somehow everyone ignored my post, so I'll repost this
http://www.ncbi.nlm....pubmed/22419870
Although this only brought complete regeneration in second-degree scalding injuries, I think it's still interesting.
This method of using EPO is based on a german patent that's been postet in this topic.
Years with veteran users understand that the solution is something that will not occur quickly, the years will pass and the solution is not found either in one or in ten years. decades pass and the solution will not appear, so hopefully future generations will see, hopefully we will see us being old and today, we're screwed us being young and very lucky to be old to see something new ... I feel very sorry for the novice users to feel hope ...
Somehow everyone ignored my post, so I'll repost this
http://www.ncbi.nlm....pubmed/22419870
Although this only brought complete regeneration in second-degree scalding injuries, I think it's still interesting.
This method of using EPO is based on a german patent that's been postet in this topic.
I just thought this was the same link that was posted on these forums a while back - Looks like this one does go into more detail though. I wonder if they've tried it on a full thickness wound...
Years with veteran users understand that the solution is something that will not occur quickly, the years will pass and the solution is not found either in one or in ten years. decades pass and the solution will not appear, so hopefully future generations will see, hopefully we will see us being old and today, we're screwed us being young and very lucky to be old to see something new ... I feel very sorry for the novice users to feel hope ...
Maldition you've got to be seeing all of the publications being posted that are claiming 'scar free healing' and 'complete skin regeneration' - Throughout your years of following this I know you haven't heard those terms used frequently referring to real achieved results. These scientists are achieving scar free healing NOW. Methods and results are clearly getting much better than they've been in the past - and they're only going to get even better. I know after so long it can be easy to lose hope - But the time may actually be getting close! You can't deny these 'scar free' results!