Well I don't know, I'm a newbie here in the world of scarless healing, they said in 2 to 3 years I guess, but it hasn't yet been tested in humans, the most important thing is whether it will work in humans!?

Well I don't know, I'm a newbie here in the world of scarless healing, they said in 2 to 3 years I guess, but it hasn't yet been tested in humans, the most important thing is whether it will work in humans!?

 

In other words....a very long time from now....it takes a tremendous amoutn of time for clinical trials and then FDA approval....**sigh** the stress is unbarable

hi, sorry for the off topic, but some time ago, I have found a pdf called "Regeneration of Mammalian Body Parts" talking about Revital and how it can heal third degree burns without scar formation, It has been tested in both animals and humans. But the FDA stopped the inventor of Revital, Dr Harry Robertson.

This has been mentioned by holdontohope in the page 26 of this topic, but it seems no one here has discussed this. Please correct me I am wrong. And, to no continue the offtopic, I would create another topic.

http://www.acne.org/messageboard/index.php/topic/317929-revital-dr-harry-robertson-curative-protein-chicken-feet/

That is a good find alonso.

No_hope, they say this will only require a few years of testing, as this is a device and as such there are no non human tested chemicals to be tested (a few pages back there was an example posted that highlighted a device being approved in 2.5years), however waiting for funding can take 5month+.

still after the testing it needs fda approval and that can take some time. id say within the next 5 years. but thats is just too long to hope and wait for. what if in the end it doesnt ive results as promised? were screwed

No_hope the device highlighted took within 2.5 years to be 'approved.' This device has been estimated at 3 year for approval.

I joined this site just to comment on this thread - after reading it for years and following the whole renovo/juvista SCAM

I'm pretty excited about the hydrogel - it does actually seem to work - and other scientific sites that are reporting on it are using terms like 'scar free' and 'complete regeneration' - plus if you look at the full paper you can actually see that yes, the mouse has regrown skin with full hair where the hydrogel has been applied - which looks like it's other normal skin

also - the fact that no drugs are involved - or stem cells - is a huge advantage, with dextran hydrogels of a different structure already used on skin - so hopefully any human safety issues wont arise

the only things that stood out in the paper was they didn't compare the regenerated mouse skin to 'normal' mouse skin - for example, to say normal skin has this many blood vessels per certain area vs regenerated skin

plus - the other thing is time - no doubt if this was 200 years ago the scientists involved would have cut one of their arms, rubbed some in, and known in a few weeks how well this would work for humans

the paper does say though that it was written in September 2011 - meaning the research would probably have been completed either [i'm guessing] then or in August - ie. nearly over a year ago - so what I'm hoping is that the team are already onto a new animal phase - but just not reporting it [i can see why research scientists don't want to give running updates to the public] - I really, really hope they are not sitting around waiting for funding applications come back!!

or - another outside chance - is that some scientists in another country have thought - that looks promising/profitable - lets copy that - and are researching as we speak - i don't know how likely that is... but I really wouldn't care how it gets here!! I just want it to arrive - or even if I just knew research was in progress it would help me deal better with my scars.

So my question is - does anyone know for sure if further research is being carried out at the moment? or is planned?

d.mars

Hard to say if any research is being done at the moment. Dr. Gerecht's lab has a website and no new publications have been published regarding the dextran hydrogel since the one last year. Here's the link:

http://www.jhu.edu/chembe/gerecht/publications.htm

I also found an application for a patent by the Johns Hopkins Technology Transfer for the hydrogels that was filed in June '10. Before the research paper last year obviously and before they knew the hydrogel would be so effective without adding growth factors etc.

My advice is if you really want to know what's going on with the research, just e-mail Dr. Gerecht and ask. I've contacted several doctors working in the fields of tissue regeneration and regenerative medicine in general and they are very forthcoming (as much as can be expected anyway). Her contact info is listed on her lab's site. Someone should give it a shot.

So its official hydrogel is gonna be our ''saviour'' or at least we hope so. =)

"Saviour"... That's a bit of a stretch, just chill, you don't wanna get overly optimistic.

You know what happened to guy who got overrly optmistic right..?

......

He died

Thanks golfpanther!

I also see from that link that for the last 3 years the team who worked on the latest paper have published one paper per year on dextran hydrogels - so i can't imagine they'd stop now after the last set of findings..

I don't want to get too overexcited - in case the testing falls down some where - but what they have done is pretty amazing - ie. no experiment before has been able to remove all the layers of skin - and then get it to regrow again scar-free - this is a first

also they don't seem to have run to the press with their findings or seem to be hyping it themselves - which I think is a good sign - other scientific blogs/magazines etc as well as people interested in skin and burns seem to have just picked up on it, and they are cautious in a good way too - but are also using the words I like > 'scar-free' and 'complete regeneration'

as for sending an email - that's kind of why I joined - to see if anyone else has - and got a response or not - I guess if an email is sent there will either be a reply with update, which would be great - or no reply - and nothing is lost!

so if anyone has sent an email - did they get a response? or does anyone know of any further research

hyrogel...hmm....i hope I get to say in the future that it changed my life!

"Saviour"... That's a bit of a stretch, just chill, you don't wanna get overly optimistic.

 

You know what happened to guy who got overrly optmistic right..?

 

......

 

He died

 

lol ya i know just being optimistic thats all . rely? was he from the org? thats messed up.

glad your back so you can warn ppl to prevent them from further scarring themeselves from treatments like dermarolling...

Hey I would just like to say that I think that you're totally right about everything you say, I know it because there is one company that develops a treatment for spinal cord injury based on that hydrogel technology, scar on the body and the face can make you a little 'ugly' (and it is highly questionable) but the problem with scars on the spinal cord is much, much more serious - it can make you permanently paralyzed so you can spend the rest of your life in a wheelchair (just because of a small scar on the spinal cord), and so I learned from their web site that there are 'acute' and 'chronic' spinal cord injuries ('chronic' are much worse) and they think that the hydrogel alone is enough for the acute spinal cord injuries, but for the chronic spinal cord injuries it will be necessary to induce neural stem cells and drugs in the hydrogel.

So all in all they were highly successful in trials with monkeys, they were able to regenerate spinal cord injuries in 40 paralyzed monkeys with hydrogel+neural stem cells+drugs treatment (few weeks after the treatment monkeys were running like crazy ), and FDA approved last month they can start with human trials with hydrogels for acute injuries and they say that their hydrogel treatment will be available on the market by the end of 2013, so that means only after 1,5 years of human trials. And for the treatment with hydrogel combined with stem cells and drugs they expect they will get FDA approval for human trials in 2015.

And they have one Nobel prize winner in an advisory board as well as some other important people. And a very important indicator that is not a scam (like Renovo) is the fact that insiders (employees of the company) currently own 37% of shares of the company (in the case of Renovo that percentage was more closer to 0%) so that should mean that they really believe in the future of their company.

So I'm very interested in that company and their work, I'll write more about it in a few days because right now I have no enough time but I will have in a few days, I think everyone will like it.

Looking forward to reading, Vladislav!

Also, I don't know if you guys have heard of this site but I think it's interesting:

http://www.petridish.org/

I wonder if Gerecht's lab would be interested in doing something like that. I know I'd give money to fund projects I thought would be of benefit to people. I think they might need to do a better job marketing though (more like Kickstarter) because I'd never heard of them until today.

Maybe we should contact Gerecht and see if she's heard of this site and if she'd be interested.

hi, sorry for the off topic, but some time ago, I have found a pdf called "Regeneration of Mammalian Body Parts" talking about Revital and how it can heal third degree burns without scar formation, It has been tested in both animals and humans. But the FDA stopped the inventor of Revital, Dr Harry Robertson.

This has been mentioned by holdontohope in the page 26 of this topic, but it seems no one here has discussed this. Please correct me I am wrong. And, to no continue the offtopic, I would create another topic.

 

http://www.acne.org/...n-chicken-feet/

 

 

revitol is already out and people have reported no signs of change with 8 months of use so i think its another scam.

@vlad does that mean hydrogel will be available for the end of next year?!?!??! if so thats amazing news!!

@vlad does that mean hydrogel will be available for the end of next year?!?!??! if so thats amazing news!!

 

No, it is intended for the treatment of spinal cord injury, not for skin scarring. And that treatment is not based on dextran hydrogel, it is based on some other hydrogel.

Looking forward to reading, Vladislav!

 

Here it is the company's website

http://www.invivotherapeutics.com/

There on that site you can find lots of information about what they are doing, there are a lot of text, pictures, videos, animations, presentations and so on.

And here is a very interesting youtube video:

Their technology is similar to that John Hopkins University hydrogel stuff:

http://www.invivotherapeutics.com/our-research/

And this is a nice presentation of their company:

http://invivotherapeutics.com/pdf/InVivo-Investor-Presentation-7-2-12.pdf

Here you can see their management team and their advisors:

http://www.invivotherapeutics.com/about-us/our-team/

Richard Roberts -1993 Nobel Laureate in Medicine

http://en.wikipedia.org/wiki/Richard_J._Roberts

Bob Langer:

http://en.wikipedia.org/wiki/Bob_Langer

George Nolen - ex-CEO of Siemens in the US (69,000 employees)

http://www.invivotherapeutics.com/about-us/our-team/george-nolen/

So skin scarring is NOTHING compared to the spinal cord scarring so KEEP YOUR SPINAL CORD SAFE!!!

BTW CEO of InVivo Therapeutics Frank Reynolds owns 22.5% of the comapny's shares (that are currently worth $34 millon) and Rober Lagner owns about 12.6% of the company's shares (that are currently worth $19 million).

Ownership

http://investing.money.msn.com/investments/five-percent-ownership?symbol=NVIV

They sold only a small portion of the shares they own in the last 2 years that are worth slightly more than $3 million (that is nothing considering that they both own shares that are worth about $50 million).

Insider Trades

http://investing.money.msn.com/investments/insider-transactions?view=All&symbol=us:NVIV

So if they decide to hold majority of their shares until the announcement of results of clinical trials that means they really believe in the future of their company and that is not a scam - so in that case if the results of the clinical trials are failure than it means they could lose up to $50 million.

hate to burst your bubble vlad but spinal cord injury's is irrelevant to this forum....

hate to burst your bubble vlad but spinal cord injury's is irrelevant to this forum....

 

No, it is not irrelevant because the same kind of technology can be used both for the scars on the spinal cord and the scars on the skin, principle is the same. And all that is regenerative medicine.

you said yourself its just for spinal cord scarring not scarring for the skin..... kinda contradicted yourself lol

in other words we can use the same hydrogel for spinal cord scarring for our facial scars?

Well I'm trying to talk about hydrogel technology in general. And of course that hydrogel mixed up with NEURAL stem cells and methylprednisolone cannot regenerate skin wounds... I said that same kind of TECHNOLOGY could be used for skin wounds, not same kind of treatment.

http://vidiowiki.com/watch/d4jgt9g/_The_ovary_as_a_model_for_scar_free_healing

revitol is already out and people have reported no signs of change with 8 months of use so i think its another scam.

 

 

Never heard of anyone using chicken feet paste/composition on wounds (can you show me where?), I know they used the 19 amino acids found in the feet in some test which failed, but that is not the chicken feet.

 

 

So my question is - does anyone know for sure if further research is being carried out at the moment? or is planned?

 

d.mars

 

The last I heard on this is that they are applying for funding, which can take 5months plus (its been about 7months since the articles were released). When they get the funding there is precedent of a devices being approved after 2.5years.

Here's the axolotl again:

http://ashleyseifert.com/research/

Im using derma rolling. I hope it helps my scarring.